MRI and fluid biomarkers reveal determinants of myelin and axonal loss with aging

por Walker, Keenan A., Duggan, Michael R., Gong, Zhaoyuan, Dark, Heather E., Laporte, John P., Faulkner, Mary E., An, Yang, Lewis, Alexandria, Moghekar, Abhay R., Resnick, Susan M., Bouhrara, Mustapha
Publicado 2023

PLP1 gene mutations cause spastic paraplegia type 2 in three families

por Yao, Li, Zhu, Zeyu, Zhang, Chao, Tian, Wotu, Cao, Li
Publicado 2023

White matter hyperintensity, neurofilament light chain, and cognitive decline

por Dhana, Anisa, DeCarli, Charles, Dhana, Klodian, Desai, Pankaja, Wilson, Robert S., Evans, Denis A., Rajan, Kumar B.
Publicado 2022

A machine learning approach to predict quality of life changes in patients with Parkinson's Disease

por Alexander, Tyler D., Nataraj, Chandrasekhar, Wu, Chengyuan
Publicado 2023

Clinicoradiologic data of familial cerebral cavernous malformation with age‐related disease burden

por Kim, Seondeuk, Moon, Jangsup, Jung, Keun‐Hwa, Anh, Seon‐Jae, Lee, Han Sang, Jang, Yoonhyuk, Park, Kyung‐Il, Lee, Sang Kun, Chu, Kon
Publicado 2023

The phenotypic and genotypic features of Chinese patients with oculopharyngeal muscular dystrophy

por Lin, Feng, Yang, Kang, Lin, Min‐ting, Zheng, Fu‐ze, Chen, Long, Ding, Yuan‐liang, Ye, Zhi‐xian, Lin, Xin, Wang, Ning, Wang, Zhi‐qiang
Publicado 2023

Common pathophysiology for ANXA11 disorders caused by aspartate 40 variants

por Natera‐de Benito, Daniel, Olival, Jonathan, Garcia‐Cabau, Carla, Jou, Cristina, Roldan, Mònica, Codina, Anna, Expósito‐Escudero, Jessica, Batlle, Cristina, Carrera‐García, Laura, Ortez, Carlos, Salvatella, Xavier, Palau, Francesc, Nascimento, Andrés, Hoenicka, Janet
Publicado 2023

Long‐term clinical, imaging and cognitive outcomes association with MS immunopathology

por Kalinowska‐Lyszczarz, Alicja, Tillema, Jan‐Mendelt, Tobin, William Oliver, Guo, Yong, Weigand, Stephen D., Metz, Imke, Brück, Wolfgang, Lassmann, Hans, Giraldo‐Chica, Monica, Port, John D., Lucchinetti, Claudia F.
Publicado 2023

Real‐world evaluation of ocrelizumab in multiple sclerosis: A systematic review

por Montalban, Xavier, Matthews, Paul M., Simpson, Alex, Petrie, John L., Sammon, Cormac, Ramagopalan, Sreeram, Disanto, Giulio, Kuhle, Jens
Publicado 2023

The potential and pitfalls of artificial intelligence in clinical pharmacology

por Johnson, Martin, Patel, Mishal, Phipps, Alex, van der Schaar, Mihaela, Boulton, Dave, Gibbs, Megan
Publicado 2023

Consistent methods for fat‐free mass, creatinine clearance, and glomerular filtration rate to describe renal function from neonates to adults

por O'Hanlon, Conor J., Holford, Nick, Sumpter, Anita, Al‐Sallami, Hesham S.
Publicado 2023

Bayesian PBPK modeling using R/Stan/Torsten and Julia/SciML/Turing.Jl

por Elmokadem, Ahmed, Zhang, Yi, Knab, Timothy, Jordie, Eric, Gillespie, William R.
Publicado 2023

FOXO3A‐short is a novel regulator of non‐oxidative glucose metabolism associated with human longevity

por Santo, Evan E., Ribel‐Madsen, Rasmus, Stroeken, Peter J., de Boer, Vincent C. J., Hansen, Ninna S., Commandeur, Maaike, Vaag, Allan A., Versteeg, Rogier, Paik, Jihye, Westerhout, Ellen M.
Publicado 2023

The influence of flip‐flop in population pharmacokinetic analyses

por Kuan, Isabelle H. S., Wright, Daniel F. B., Duffull, Stephen B.
Publicado 2023

N‐homocysteinylation of α‐synuclein promotes its aggregation and neurotoxicity

por Zhou, Lingyan, Guo, Tao, Meng, Lanxia, Zhang, Xingyu, Tian, Ye, Dai, Lijun, Niu, Xuan, Li, Yiming, Liu, Congcong, Chen, Guiqin, Liu, Chaoyang, Ke, Wei, Zhang, Zhaohui, Bao, Anyu, Zhang, Zhentao
Publicado 2022

Treatment with the senolytics dasatinib/quercetin reduces SARS‐CoV‐2‐related mortality in mice

por Pastor‐Fernández, Andrés, Bertos, Antonio R., Sierra‐Ramírez, Arantzazu, del Moral‐Salmoral, Javier, Merino, Javier, de Ávila, Ana I., Olagüe, Cristina, Villares, Ricardo, González‐Aseguinolaza, Gloria, Rodríguez, María Ángeles, Fresno, Manuel, Gironés, Nuria, Bustos, Matilde, Smerdou, Cristian, Fernandez‐Marcos, Pablo Jose, von Kobbe, Cayetano
Publicado 2023

Notch activation shifts the fate decision of senescent progenitors toward myofibrogenesis in human adipose tissue

por Boulet, Nathalie, Briot, Anaïs, Jargaud, Valentin, Estève, David, Rémaury, Anne, Belles, Chloé, Viana, Pénélope, Fontaine, Jessica, Murphy, Lucie, Déon, Catherine, Guillemot, Marie, Pech, Catherine, Veeranagouda, Yaligara, Didier, Michel, Decaunes, Pauline, Mouisel, Etienne, Carpéné, Christian, Iacovoni, Jason S., Zakaroff‐Girard, Alexia, Grolleau, Jean‐Louis, Galitzky, Jean, Ledoux, Séverine, Guillemot, Jean‐Claude, Bouloumié, Anne
Publicado 2023

Quantitative systems pharmacology model of GITR‐mediated T cell dynamics in tumor microenvironment

por Ji, Yan, Madrasi, Kumpal, Knee, Deborah A., Gruenbaum, Lore, Apgar, Joshua F., Burke, John M., Gomes, Bruce
Publicado 2023

Neuronal HLH‐30/TFEB modulates peripheral mitochondrial fragmentation to improve thermoresistance in Caenorhabditis elegans

por Wong, Shi Quan, Ryan, Catherine J., Bonal, Dennis M., Mills, Joslyn, Lapierre, Louis R.
Publicado 2022

Verifying in vitro‐determined enzyme contributions to cannabidiol clearance for exposure predictions in human through physiologically‐based pharmacokinetic modeling

por Yeung, Cindy H. T., Beers, Jessica L., Jackson, Klarissa D., Edginton, Andrea N.
Publicado 2023