Hydroxychloroquine for treatment of non‐hospitalized adults with COVID‐19: A meta‐analysis of individual participant data of randomized trials

por Mitjà, Oriol, Reis, Gilmar, Boulware, David R., Spivak, Adam M., Sarwar, Ammar, Johnston, Christine, Webb, Brandon, Hill, Michael D., Smith, Davey, Kremsner, Peter, Curran, Marla, Carter, David, Alexander, Jim, Corbacho, Marc, Lee, Todd C., Hullsiek, Katherine Huppler, McDonald, Emily G., Hess, Rachel, Hughes, Michael, Baeten, Jared M., Schwartz, Ilan, Metz, Luanne, Richer, Lawrence, Chew, Kara W., Daar, Eric, Wohl, David, Dunne, Michael
Publicado 2023

First‐in‐human study of JNJ‐63709178, a CD123/CD3 targeting antibody, in relapsed/refractory acute myeloid leukemia

por Boyiadzis, Michael, Desai, Pinkal, Daskalakis, Nikki, Donnellan, William, Ferrante, Lucille, Goldberg, Jenna D., Grunwald, Michael R., Guttke, Christina, Li, Xiang, Perez‐Simon, Jose Antonio, Salamero, Olga, Tucker, Trevor, Xu, Xiaoying, Yang, Jay, Pemmaraju, Naveen, Alonso‐Dominguez, Juan Manuel
Publicado 2023

Evaluation of levocetirizine in beagle dog and cynomolgus monkey telemetry assays: Defining the no QTc effect profile by timepoint and concentration‐QTc analysis

por Engwall, Michael J., Baublits, Joel, Chandra, Fiona A., Jones, Zack W., Wahlstrom, Jan, Chui, Ray W., Vargas, Hugo M.
Publicado 2022

Clinical, methodology, and patient/carer expert advice in pediatric drug development by conect4children

por Cheng, Katharine, Mahler, Fenna, Lutsar, Irja, Nafria Escalera, Begonya, Breitenstein, Stefanie, Vassal, Gilles, Claverol, Joana, Noel Palacio, Nuria, Portman, Ron, Pope, Gavin, Bakker, Martijn, van der Geest, Tessa, Turner, Mark A., de Wildt, Saskia N.
Publicado 2022

CARE program: NCI and FDA interagency collaborations to support oncology small business entrepreneurs

por Pond, Monique A., Narayanan, Deepa, Zhang, Kehui, Fau, Danielle, Summers, Jeffrey, Carranza, Dorn, Weingarten, Michael
Publicado 2023

Empowering drug development: Leveraging insights from imaging technologies to enable the advancement of digital health technologies

por Izmailova, Elena S., Maguire, R. Paul, McCarthy, Timothy J., Müller, Martijn L. T. M., Murphy, Philip, Stephenson, Diane
Publicado 2022

Using an animal model to predict the effective human dose for oral multiple sclerosis drugs

por Liu, Wei, Yu, Zhiheng, Wang, Ziyu, Waubant, Emmanuelle L., Zhai, Suodi, Benet, Leslie Z.
Publicado 2022

In vivo human keyhole limpet hemocyanin challenge in early phase drug development: A systematic review

por Drennan, Philip G., Karponis, Dimitrios, Richards, Duncan, Coles, Mark, Fullerton, James N.
Publicado 2022

Noninvasive assessment of carotid plaque with subharmonic aided pressure estimation from a US contrast agent: A preliminary study

por Li, Rui, Zhang, Yukang, Zheng, Shuai, Cheng, Linggang, Zhang, Yanfen, Chen, Zhiguang, He, Wen, Zhang, Wei
Publicado 2023

The randomized, single‐ and multiple‐ ascending dose studies of the safety, tolerability, pharmacokinetics of CSPCHA115 in healthy Chinese subjects

por Jing, Shan, Liu, Wenfang, Yang, Kexu, Lin, Yang, Yao, Xuekun, Sun, Guilan
Publicado 2022

The impact of genetic variability in urate transporters on oxypurinol pharmacokinetics

por Hishe, Hailemichael Z., Stocker, Sophie L., Stamp, Lisa K., Dalbeth, Nicola, Merriman, Tony R., Phipps‐Green, Amanda, Wright, Daniel F. B.
Publicado 2022

The relationship between high density lipoprotein cholesterol and sepsis: A clinical and genetic approach

por Liu, Ge, Jiang, Lan, Kerchberger, V. Eric, Oeser, Annette, Ihegword, Andrea, Dickson, Alyson L., Daniel, Laura L., Shaffer, Christian, Linton, MacRae F., Cox, Nancy, Chung, Cecilia P., Wei, Wei‐Qi, Stein, C. Michael, Feng, QiPing
Publicado 2023

Distinct microbial communities across a climatically versatile summit in the Lesotho highlands

por Patel, Jasmin, Grab, Stefan, De Maayer, Pieter
Publicado 2023

Sexual size and shape dimorphism, and allometric scaling in the pupal and adult traits of Eristalis tenax

por Ludoški, Jasmina, Francuski, Ljubinka, Gojković, Nemanja, Matić, Bojana, Milankov, Vesna
Publicado 2023

Predation of endangered Arctic foxes by Golden eagles: What do we know?

por Jackson, Craig R., Rød‐Eriksen, Lars, Mattisson, Jenny, Flagstad, Øystein, Landa, Arild, Miller, Andrea L., Eide, Nina E., Ulvund, Kristine Roaldsnes
Publicado 2023

A DNA barcode reference library for CITES listed Malagasy Dalbergia species

por Rakotonirina, Tahinarizaka Jenny, Viljoen, Erika, Rakotonirina, Antso Harimanantsoa, Leong Pock Tsy, Jean Michel, Radanielina, Tendro
Publicado 2023

Differential genotype response to increased resource abundance helps explain parallel evolution of Daphnia populations in the wild

por Lyberger, Kelsey, Schoener, Thomas W.
Publicado 2023

Red deer Cervus elaphus blink more in larger groups

por Rowe, Zeke W., Robins, Joseph H., Rands, Sean A.
Publicado 2023

BRD4‐PRC2 represses transcription of T‐helper 2‐specific negative regulators during T‐cell differentiation

por Zhao, Li, Wang, Yiqi, Jaganathan, Anbalagan, Sun, Yifei, Ma, Ning, Li, Ning, Han, Xinye, Sun, Xueying, Yi, Huanfa, Fu, Shibo, Han, Fangbin, Li, Xue, Xiao, Kunhong, Walsh, Martin J, Zeng, Lei, Zhou, Ming‐Ming, Cheung, Ka Lung
Publicado 2023

Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL‐10

por Richter, Felix Clemens, Friedrich, Matthias, Kampschulte, Nadja, Piletic, Klara, Alsaleh, Ghada, Zummach, Ramona, Hecker, Julia, Pohin, Mathilde, Ilott, Nicholas, Guschina, Irina, Wideman, Sarah Karin, Johnson, Errin, Borsa, Mariana, Hahn, Paula, Morriseau, Christophe, Hammock, Bruce D, Schipper, Henk Simon, Edwards, Claire M, Zechner, Rudolf, Siegmund, Britta, Weidinger, Carl, Schebb, Nils Helge, Powrie, Fiona, Simon, Anna Katharina
Publicado 2023