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  1. 1269301
    “…Biguanide metformin is the first‐line and most widely prescribed anti‐diabetic drug for patients with type 2 diabetes. …”
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    Metformin induces muscle atrophy by transcriptional regulation of myostatin via HDAC6 and FoxO3a
  2. 1269302
    “…Importantly, we found that pH240R did not affect virus-cell binding, endocytosis, or egress but did affect ASFV assembly; noninfectious virions containing large aberrant tubular and bilobulate structures comprised nearly 98% of all virions observed in ASFV-ΔH240R-infected PAMs by electron microscopy. …”
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    Deletion of the H240R Gene of African Swine Fever Virus Decreases Infectious Progeny Virus Production Due to Aberrant Virion Morphogenesis and Enhances Inflammatory Cytokine Expression in Porcine Macrophages
  3. 1269303
    “…Realizamos o teste de normalidade de Shapiro-Wilk e o teste t de student para amostras pareadas. …”
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    PERFIL DE MICRORGANISMOS E DE RESISTÊNCIA AOS ANTIMICROBIANOS EM UM HOSPITAL PÚBLICO DE REFERÊNCIA PARA TRATAMENTO DE COVID-19 NO ESPÍRITO SANTO ANTES E DURANTE O PRIMEIRO ANO DA PANDEMIA
  4. 1269304
    por Tshikudi, D M, Eissa, N, Diarra, A, Ghia, J
    Publicado 2022
    “…Chromogranin-A (CHGA), a pro-peptide secreted by enteroendocrine cells, is highly expressed in colonic tissues of patients with UC. …”
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    A182 THE LACK OF CHROMOGRANIN A IMPACTS COLONIC EPITHELIAL CELLS MARKERS IN AN EXPERIMENTAL MODEL OF ULCERATIVE COLITIS
  5. 1269305
    “…However, the role of PAF1C in the regulation of flowering time at chilling temperatures (i.e., cold temperatures that are above freezing) and whether PAF1C affects other FLC-clade genes (MAF2–MAF5) remains unknown. …”
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    Polymerase II–Associated Factor 1 Complex-Regulated FLOWERING LOCUS C-Clade Genes Repress Flowering in Response to Chilling
  6. 1269306
    “…SIMPLE SUMMARY: Genetic resources on turkeys are scarce, considering both domestic and wild birds. Smaller, dark-colored Italian heritage breeds such as Brianzolo and Nero d’Italia have been selected for centuries in outskirt areas due to their coping ability in poor environments and high brooding ability. …”
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    Morphological Characterization of Two Light Italian Turkey Breeds
  7. 1269307
    “…Compared to E3, E4 increases while E2 protects against AD risk. At 6 months of age, prior to the onset of plaque pathology, E3, but not E4, protected against hAPP/Aβ-induced impairments in spatial memory retention in the Morris water maze. …”
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    Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced Behavioral Alterations and Cognitive Impairments and Insoluble Cortical Aβ42 Levels
  8. 1269308
    “…Surrogate virus neutralization test (sVNT) against wild type and delta variant, and anti-spike-receptor-binding-domain IgG (anti-S-RBD IgG) were compared as geometric mean ratio (GMR) at day 14 and 90 between LD and SD arms. …”
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    A randomized clinical trial of a booster dose with low versus standard dose of AZD1222 in adult after 2 doses of inactivated vaccines
  9. 1269309
    “…This study tested that hypothesis by identifying all non-native bees among 11,275 bees previously collected from 45 species of flowering woody plants across hundreds of urban sites. …”
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    Non-Native Non-Apis Bees Are More Abundant on Non-Native Versus Native Flowering Woody Landscape Plants
  10. 1269310
    “…Neuron-sparing surgery was performed in 56 cases (40%), while percutane-ous thermal ablation (TA) in 84 cases (60%). …”
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    Comparison of the Results of Therapy for cT1 Renal Carcinoma with Nephron-Sparing Surgery (NSS) vs. Percutaneous Thermal Ablation (TA)
  11. 1269311
    “…RESULTS: In this study, we discovered a novel activity of U-STAT1 that alters the nucleo-cytoplasmic distribution of cytokine-stimulated P-STAT1. While the dimerization-deficient mutant R602L/Y701F was not able to display cytokine-induced nuclear accumulation, it inhibited the nuclear accumulation of co-expressed IFNγ-stimulated wild-type P-STAT1. …”
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    An inhibitory effect on the nuclear accumulation of phospho-STAT1 by its unphosphorylated form
  12. 1269312
    “…In addition, clay pots were placed outside the hut to collect outdoor resting mosquitoes. The F1 progeny of wild-caught mosquitoes were also used in these experiments. …”
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    Behavioral responses of pyrethroid resistant and susceptible Anopheles gambiae mosquitoes to insecticide treated bed net
  13. 1269313
    “…Hut tests were conducted against free-flying wild pyrethroid metabolically resistant Anopheles arabiensis and Culex quinquefasciatus. …”
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    Influence of testing modality on bioefficacy for the evaluation of Interceptor(®) G2 mosquito nets to combat malaria mosquitoes in Tanzania
  14. 1269314
    “…To the best of our knowledge, the present study was the first to report co-expression of p53 and aurora kinase family members in MIBC, and although wild-type p53 may regulate the aurora kinases in preclinical models, the adverse prognostic value of tumor AURKA overexpression was independent from baseline tumor p53 protein expression in the present cohort. …”
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    Clinical outcomes associated with expression of aurora kinase and p53 family members in muscle-invasive bladder cancer
  15. 1269315
    “…Transformed U937 AML cells over-expressing WT BCAT1, showed lower levels of intracellular ROS compared with cells over-expressing the CXXC motif mutant (CXXS) or Vector Controls, indicating that the BCAT1 CXXC motif may buffer intracellular ROS, impacting on cell proliferation. …”
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    The BCAT1 CXXC Motif Provides Protection against ROS in Acute Myeloid Leukaemia Cells
  16. 1269316
    “…Since phrenic motoneuron pools are located at the C3–C5 spinal level, we investigated two models of preclinical cSCI mimicking human forms of injury, namely, one above (C3 hemicontusion—C3HC) and one below phrenic motoneuron pools (C6HC) in wild-type swiss OF-1 mice, and we compared their effects on respiratory function using whole-body plethysmography and on diaphragm activity using electromyography (EMG). …”
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    Diaphragmatic Activity and Respiratory Function Following C3 or C6 Unilateral Spinal Cord Contusion in Mice
  17. 1269317
    “…All of the 1RS arms in 1BL.1RS and 1AL.1RS translocations contained pSc119.2, pTa71, pSc200 and pSc250, but the presence of the TaiI family was not observed. …”
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    Variations of subtelomeric tandem repeats and rDNA on chromosome 1RS arms in the genus Secale and 1BL.1RS translocations
  18. 1269318
    “…The constraint is difficult to overcome as chickpea germplasm including wild species either lacks pod borer resistance or if possessing resistance is cross-incompatible. …”
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    Introgressing cry1Ac for Pod Borer Resistance in Chickpea Through Marker-Assisted Backcross Breeding
  19. 1269319
    “…The study included 133 patients [53% AL, 41% wild‐type (wt) ATTR‐CA, & 6% hereditary ATTR‐CA]. …”
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    Clinical features and predictors of atrial fibrillation in patients with light‐chain or transthyretin cardiac amyloidosis
  20. 1269320
    “…The distribution of variables was checked with Shapiro-Wilk tests. The Mann–Whitney U test was used to compare two independent samples, while the Kruskal–Wallis test was used to compare more samples. …”
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    Stress coping strategies used by nurses during the COVID-19 pandemic
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