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1269641“…Small intestinal segments were stained for tuft (DCLK1(+)) and goblet cells (PAS(+)). As a surrogate of successful infection, IL-4 and IL-10 were measured in supernatants from concanavalin-A treated splenocytes. …”
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1269642por Zhang, Jing, Yuan, Quan, Wang, Yongxiang, Wang, Yuzhou, Yuan, Wenqing, Xia, Ningshao, Wen, Yumei, Li, Jisu, Tong, Shuping“…Cotransfection with an expression construct for L/M proteins reversed high extracellular p41/p44 associated with L-minus mutants, suggesting that L protein retains p43 in wild-type HBV to promote its intracellular degradation. …”
Publicado 2022
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1269643por Moyo, Anesu Conrad, Dufossé, Laurent, Giuffrida, Daniele, van Zyl, Leonardo Joaquim, Trindade, Marla“…Eight candidate genes, likely responsible for C(30)-carotenoid biosynthesis, were identified on the wild-type genome region corresponding to the deleted segment in the non-pigmented mutant. …”
Publicado 2022
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1269644por Meng, Xiangkun, Huang, Zhe, Inoue, Aiko, Wang, Hailong, Wan, Ying, Yue, Xueling, Xu, Shengnan, Jin, Xueying, Shi, Guo‐Ping, Kuzuya, Masafumi, Cheng, Xian Wu“…METHODS: Male 9‐week‐old wild‐type (CTSK(+/+), n = 10) and CTSK‐knockout (CTSK(−/−), n = 10) mice were injected subcutaneously with Lewis lung carcinoma cells (LLC; 5 × 10(5)) or saline, respectively. …”
Publicado 2022
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1269645por Sadeghzadeh, Hadi, Mehdipour, Ahmad, Dianat-Moghadam, Hassan, Salehi, Roya, Khoshfetrat, Ali Baradar, Hassani, Ayla, Mohammadnejad, Daryush“…Magnetism promotes stem cells' adherence to biocompatible scaffolds toward osteoblast differentiation. …”
Publicado 2022
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1269646“…Most members of the general public find it difficult to identify poisonous wild mushrooms, resulting in family food poisoning. …”
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1269647por Nantanee, Rapisa, Aikphaibul, Puneyavee, Jaru-Ampornpan, Peera, Sodsai, Pimpayao, Himananto, Orawan, Theerawit, Tuangtip, Sophonphan, Jiratchaya, Tovichayathamrong, Punyot, Manothummetha, Kasama, Laohasereekul, Tysdi, Hiransuthikul, Narin, Hirankarn, Nattiya, Puthanakit, Thanyawee“…Antibody responses were evaluated by surrogate virus neutralization test(sVNT) against delta variant and wild type, and anti-spike-receptor-binding-domain immunoglobulin G(anti-S-RBD IgG) at prior, day14, 28, 90, and 180 post booster. …”
Publicado 2022
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1269648por Han, Sida, Feng, Yiwei, Guo, Min, Hao, Yining, Sun, Jian, Zhao, Yichen, Dong, Qiang, Zhao, Yanxin, Cui, Mei“…METHODS: Models of PQ-induced neurodegeneration were established by intraperitoneal (i.p.) injection of PQ in wild-type (WT) and organic cation transporter-3–deficient ([Formula: see text]) mice. …”
Publicado 2022
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1269649por Chang, Chun-Chao, Kao, Wei-Yu, Liu, Chih-Yi, Su, Hui-Hsien, Kan, Yu-An, Lin, Pao-Ying, Ku, Wei-Chi, Chang, Kang-Wei, Yang, Ruey-Neng, Huang, Chi-Jung“…Furthermore, in HCT116 p53(−/−) cells, CSE1L expression was already high at interphase, increased at prophase, peaked during metaphase before declining at cytokinesis but remained relatively high compared with that in HCT116 expressing wild-type p53. …”
Publicado 2022
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1269650“…Cytotoxicity assay showed that AWME3 is safe for human HEK293 cells at IC(50) 266.1 μg/ml, while bactericidal for all the strains of bacteria at the same concentration. …”
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1269651por Li, Muyang, Philantrope, Fredrick, Diot, Alexandra, Bourdon, Jean-Christophe, Thompson, Patricia“…We show that SMG1, a phosphatidylinositol 3-kinase-related kinase, when inhibited in p53 wild-type MCF7 and HepG2 cells, significantly alters the expression of cholesterol pathway genes, with a net increase in intracellular cholesterol and an increased sensitivity to Fatostatin in MCF7. …”
Publicado 2022
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1269652por Damuka, Naresh, Orr, Miranda E., Bansode, Avinash H., Krizan, Ivan, Miller, Mack, Lee, Jillian, Macauley, Shannon L., Whitlow, Christopher T., Mintz, Akiva, Craft, Suzanne, Solingapuram Sai, Kiran Kumar“…Target engagement and mechanism of action using in vitro, in vivo, and ex vivo methods were evaluated here. METHODS: In vitro cell uptake assay was performed in SH-SY5Y neuronal cells with [(11)C]MPC-6827, with various MT stabilizing and destabilizing agents. …”
Publicado 2022
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1269653“…However, the mechanism behind the loss of adipose tissue remains ill-defined. In this study, we found that cancer cell-derived exosomes highly expressed miR-425-3p. …”
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1269654por Jin, Jianjun, Du, Mengmeng, Wang, Jian, Guo, Yubo, Zhang, Jiali, Zuo, Hao, Hou, Yunqing, Wang, Shanshan, Lv, Wei, Bai, Wei, Wang, Jin, Zhan, Xizhen, Peng, Yaxin, Tong, Qian, Chai, Jin, Xu, Zaiyan, Zuo, Bo“…The tibialis anterior (TA) muscle weight of 3‐month‐old wild‐type (WT) mice decreased by 33.24% after DEX treatment (P < 0.001), while the muscle weight loss of 3‐month‐old SYISL knockout mice was only 18.20% after DEX treatment (P < 0.001). …”
Publicado 2022
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1269655por Bruno, Silvia, Landi, Vincenzo, Senczuk, Gabriele, Brooks, Samantha Ann, Almathen, Faisal, Faye, Bernard, Gaouar, Suheil Semir Bechir, Piro, Mohammed, Kim, Kwan Suk, David, Xavier, Eggen, André, Burger, Pamela, Ciani, Elena“…A sequence comparative analysis among the three species within the Camelus genus confirmed the expected higher genetic distance of C. dromedarius from the wild and domestic two-humped camels compared to the genetic distance between C. bactrianus and C. ferus. …”
Publicado 2022
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1269656por Sukhan, Zahid Parvez, Cho, Yusin, Hossen, Shaharior, Yang, Seok-Woo, Hwang, Nam-Yong, Lee, Won Kyo, Kho, Kang Hee“…Due to a decline in production in the wild, marine aquaculture has been initiated in Korea. …”
Publicado 2022
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1269657por Bisetegn, Habtye, Feleke, Daniel Getacher, Debash, Habtu, Erkihun, Yonas, Ebrahim, Hussen“…BACKGROUND: Schistosomes are blood dwelling parasites that affect more than 260 million people globally, and over 800 million people are at risk of infection in 74 countries. …”
Publicado 2022
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1269658por Xu, Xiaoyan, Zheng, Guangmei, Ren, Yushan, He, Xiaohua, Peng, Biwen, Hu, Xuemei, Liu, Wanhong“…METHODS: Toxoplasma gondii-infected wild-type (WT) pregnant mice and 2B4 knockout (2B4(−/−)) pregnant mice were established for in vivo study. …”
Publicado 2022
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1269659por Nyuykonge, Bertrand, Siddig, Emmanuel, Mhmoud, Najwa, Nyaoke, Borna, Zijlstra, Ed, Verbon, Annelies, Bakhiet, Sahar, Fahal, Ahmed, Van de Sande, Wendy“…S4.5 MYCETOMA CLINICAL TRIAL ON FOSRAVUCONAZOLE TREATMENT IN EUMYCETOMA– TOP LINE RESULTS, SEPTEMBER 22, 2022, 10:30 AM - 12:00 PM: OBJECTIVES: Eumycetoma is a neglected tropical disease characterized by large subcutaneous swellings and the formation of grains and most commonly caused by Madurella mycetomatis. …”
Publicado 2022
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1269660“…METHODS: Young (2 month) and old (18 month) wild‐type (WT) and PGC1α transgenic male and female mice (Tg) were injected with cisplatin (C; 2.5 mg/kg) for 2 weeks, while control animals received saline (n = 5–9/group). …”
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