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  1. 1269701
    “…Nearly all subgroups demonstrated robust and continuous increases in CD4+ T-cell count from Weeks 96 to 240, with mean change from BL exceeding 200 cells/mm(3) in all RC subgroups, including those with BL viral loads ≥ 100,000 c/mL or CD4+ T-cell counts < 20 cells/mm(3) (Table 2). …”
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    365. Durable efficacy and robust CD4+ T-cell count improvement observed across age, race, sex, and geographic subgroups of heavily treatment-experienced people with multidrug-resistant HIV-1 after 240 weeks of fostemsavir treatment
  2. 1269702
    “…CONCLUSION: We uncovered an MRSA-specific host transcriptional signature that was driven in large part by suppressed mitochondrial responses necessary for essential immune functions in oxidative killing of S. aureus. Given the importance of respiratory functions and reactive oxygen species in eliminating intracellular S. aureus, this finding may offer new insights into persistence of MRSA BSI relative to other bacteria. …”
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    240. Transcriptional signatures differentiate pathogen- and treatment-specific host responses in patients with bacterial bloodstream infections
  3. 1269703
    por Marine, David, Lenhart, C. H.
    Publicado 1911
    “…The effect of iodin on the thyroid hyperplasia has been studied in the early, middle, and late stages. All stages react with iodin, the mild degrees seemingly more rapidly than the severer degrees. …”
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    FURTHER OBSERVATIONS AND EXPERIMENTS ON THE SO-CALLED THYROID CARCINOMA OF THE BROOK TROUT (SALVELINUS FONTINALIS) AND ITS RELATION TO ENDEMIC GOITRE
  4. 1269704
    por Noguchi, Hideyo, Akatsu, Seinai
    Publicado 1917
    “…Many of the anti-pallidum sera killed their own strains. Normal rabbit serum exhibited only a slight degree of inhibition. …”
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    IMMUNOLOGICAL STUDIES ON PURE CULTURES OF VARIOUS SPIROCHETES
  5. 1269705
    por Blake, Francis G., Cecil, Russell L.
    Publicado 1920
    “…While all the above features of the disease produced in monkeys are characteristic of influenza in man, none are pathognomonic and, in fact, it is doubtful whether uncomplicated influenza possesses any pathognomonic features by which it may be diagnosed certainly in the absence of an epidemic. …”
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    STUDIES ON EXPERIMENTAL PNEUMONIA : IX. PRODUCTION IN MONKEYS OF AN ACUTE RESPIRATORY DISEASE RESEMBLING INFLUENZA BY INOCULATION WITH BACILLUS INFLUENZÆ.
  6. 1269706
    por Lurie, Max B.
    Publicado 1929
    “…In 1925 and 1926 0.01 mg. of this bovine strain regularly killed rabbits in about 30 days after intravenous inoculation (8), but in this experiment none of the 3 rabbits died within 65 days after a similar infection and 2 rabbits were still living 110 days after injection.…”
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    THE FATE OF TUBERCLE BACILLI IN THE ORGANS OF REINFECTED RABBITS
  7. 1269707
    “…RESULTS: Key recommendations, listed by category, include: early goal-directed resuscitation of the septic patient during the first 6 hrs after recognition (1C); blood cultures prior to antibiotic therapy (1C); imaging studies performed promptly to confirm potential source of infection (1C); administration of broad-spectrum antibiotic therapy within 1 hr of diagnosis of septic shock (1B) and severe sepsis without septic shock (1D); reassessment of antibiotic therapy with microbiology and clinical data to narrow coverage, when appropriate (1C); a usual 7–10 days of antibiotic therapy guided by clinical response (1D); source control with attention to the balance of risks and benefits of the chosen method (1C); administration of either crystalloid or colloid fluid resuscitation (1B); fluid challenge to restore mean circulating filling pressure (1C); reduction in rate of fluid administration with rising filing pressures and no improvement in tissue perfusion (1D); vasopressor preference for norepinephrine or dopamine to maintain an initial target of mean arterial pressure ≥ 65 mm Hg (1C); dobutamine inotropic therapy when cardiac output remains low despite fluid resuscitation and combined inotropic/vasopressor therapy (1C); stress-dose steroid therapy given only in septic shock after blood pressure is identified to be poorly responsive to fluid and vasopressor therapy (2C); recombinant activated protein C in patients with severe sepsis and clinical assessment of high risk for death (2B except 2C for post-operative patients). …”
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    Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
  8. 1269708
    por Estrada, Karol, Styrkarsdottir, Unnur, Evangelou, Evangelos, Hsu, Yi-Hsiang, Duncan, Emma L, Ntzani, Evangelia E, Oei, Ling, Albagha, Omar M E, Amin, Najaf, Kemp, John P, Koller, Daniel L, Li, Guo, Liu, Ching-Ti, Minster, Ryan L, Moayyeri, Alireza, Vandenput, Liesbeth, Willner, Dana, Xiao, Su-Mei, Yerges-Armstrong, Laura M, Zheng, Hou-Feng, Alonso, Nerea, Eriksson, Joel, Kammerer, Candace M, Kaptoge, Stephen K, Leo, Paul J, Thorleifsson, Gudmar, Wilson, Scott G, Wilson, James F, Aalto, Ville, Alen, Markku, Aragaki, Aaron K, Aspelund, Thor, Center, Jacqueline R, Dailiana, Zoe, Duggan, David J, Garcia, Melissa, Garcia-Giralt, Natàlia, Giroux, Sylvie, Hallmans, Göran, Hocking, Lynne J, Husted, Lise Bjerre, Jameson, Karen A, Khusainova, Rita, Kim, Ghi Su, Kooperberg, Charles, Koromila, Theodora, Kruk, Marcin, Laaksonen, Marika, Lacroix, Andrea Z, Lee, Seung Hun, Leung, Ping C, Lewis, Joshua R, Masi, Laura, Mencej-Bedrac, Simona, Nguyen, Tuan V, Nogues, Xavier, Patel, Millan S, Prezelj, Janez, Rose, Lynda M, Scollen, Serena, Siggeirsdottir, Kristin, Smith, Albert V, Svensson, Olle, Trompet, Stella, Trummer, Olivia, van Schoor, Natasja M, Woo, Jean, Zhu, Kun, Balcells, Susana, Brandi, Maria Luisa, Buckley, Brendan M, Cheng, Sulin, Christiansen, Claus, Cooper, Cyrus, Dedoussis, George, Ford, Ian, Frost, Morten, Goltzman, David, González-Macías, Jesús, Kähönen, Mika, Karlsson, Magnus, Khusnutdinova, Elza, Koh, Jung-Min, Kollia, Panagoula, Langdahl, Bente Lomholt, Leslie, William D, Lips, Paul, Ljunggren, Östen, Lorenc, Roman S, Marc, Janja, Mellström, Dan, Obermayer-Pietsch, Barbara, Olmos, José M, Pettersson-Kymmer, Ulrika, Reid, David M, Riancho, José A, Ridker, Paul M, Rousseau, François, Slagboom, P Eline, Tang, Nelson LS, Urreizti, Roser, Van Hul, Wim, Viikari, Jorma, Zarrabeitia, María T, Aulchenko, Yurii S, Castano-Betancourt, Martha, Grundberg, Elin, Herrera, Lizbeth, Ingvarsson, Thorvaldur, Johannsdottir, Hrefna, Kwan, Tony, Li, Rui, Luben, Robert, Medina-Gómez, Carolina, Palsson, Stefan Th, Reppe, Sjur, Rotter, Jerome I, Sigurdsson, Gunnar, van Meurs, Joyce B J, Verlaan, Dominique, Williams, Frances MK, Wood, Andrew R, Zhou, Yanhua, Gautvik, Kaare M, Pastinen, Tomi, Raychaudhuri, Soumya, Cauley, Jane A, Chasman, Daniel I, Clark, Graeme R, Cummings, Steven R, Danoy, Patrick, Dennison, Elaine M, Eastell, Richard, Eisman, John A, Gudnason, Vilmundur, Hofman, Albert, Jackson, Rebecca D, Jones, Graeme, Jukema, J Wouter, Khaw, Kay-Tee, Lehtimäki, Terho, Liu, Yongmei, Lorentzon, Mattias, McCloskey, Eugene, Mitchell, Braxton D, Nandakumar, Kannabiran, Nicholson, Geoffrey C, Oostra, Ben A, Peacock, Munro, Pols, Huibert A P, Prince, Richard L, Raitakari, Olli, Reid, Ian R, Robbins, John, Sambrook, Philip N, Sham, Pak Chung, Shuldiner, Alan R, Tylavsky, Frances A, van Duijn, Cornelia M, Wareham, Nick J, Cupples, L Adrienne, Econs, Michael J, Evans, David M, Harris, Tamara B, Kung, Annie Wai Chee, Psaty, Bruce M, Reeve, Jonathan, Spector, Timothy D, Streeten, Elizabeth A, Zillikens, M Carola, Thorsteinsdottir, Unnur, Ohlsson, Claes, Karasik, David, Richards, J Brent, Brown, Matthew A, Stefansson, Kari, Uitterlinden, André G, Ralston, Stuart H, Ioannidis, John P A, Kiel, Douglas P, Rivadeneira, Fernando
    Publicado 2012
    “…We identified 56 loci (32 novel)associated with BMD atgenome-wide significant level (P<5×10(−8)). Several of these factors cluster within the RANK-RANKL-OPG, mesenchymal-stem-cell differentiation, endochondral ossification and the Wnt signalling pathways. …”
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    Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
  9. 1269709
    por Jacobs, Kevin B, Yeager, Meredith, Zhou, Weiyin, Wacholder, Sholom, Wang, Zhaoming, Rodriguez-Santiago, Benjamin, Hutchinson, Amy, Deng, Xiang, Liu, Chenwei, Horner, Marie-Josephe, Cullen, Michael, Epstein, Caroline G, Burdett, Laurie, Dean, Michael C, Chatterjee, Nilanjan, Sampson, Joshua, Chung, Charles C, Kovaks, Joseph, Gapstur, Susan M, Stevens, Victoria L, Teras, Lauren T, Gaudet, Mia M, Albanes, Demetrius, Weinstein, Stephanie J, Virtamo, Jarmo, Taylor, Philip R, Freedman, Neal D, Abnet, Christian C, Goldstein, Alisa M, Hu, Nan, Yu, Kai, Yuan, Jian-Min, Liao, Linda, Ding, Ti, Qiao, You-Lin, Gao, Yu-Tang, Koh, Woon-Puay, Xiang, Yong-Bing, Tang, Ze-Zhong, Fan, Jin-Hu, Aldrich, Melinda C, Amos, Christopher, Blot, William J, Bock, Cathryn H, Gillanders, Elizabeth M, Harris, Curtis C, Haiman, Christopher A, Henderson, Brian E, Kolonel, Laurence N, Le Marchand, Loic, McNeill, Lorna H, Rybicki, Benjamin A, Schwartz, Ann G, Signorello, Lisa B, Spitz, Margaret R, Wiencke, John K, Wrensch, Margaret, Wu, Xifeng, Zanetti, Krista A, Ziegler, Regina G, Figueroa, Jonine D, Garcia-Closas, Montserrat, Malats, Nuria, Marenne, Gaelle, Prokunina-Olsson, Ludmila, Baris, Dalsu, Schwenn, Molly, Johnson, Alison, Landi, Maria Teresa, Goldin, Lynn, Consonni, Dario, Bertazzi, Pier Alberto, Rotunno, Melissa, Rajaraman, Preetha, Andersson, Ulrika, Freeman, Laura E Beane, Berg, Christine D, Buring, Julie E, Butler, Mary A, Carreon, Tania, Feychting, Maria, Ahlbom, Anders, Gaziano, J Michael, Giles, Graham G, Hallmans, Goran, Hankinson, Susan E, Hartge, Patricia, Henriksson, Roger, Inskip, Peter D, Johansen, Christoffer, Landgren, Annelie, McKean-Cowdin, Roberta, Michaud, Dominique S, Melin, Beatrice S, Peters, Ulrike, Ruder, Avima M, Sesso, Howard D, Severi, Gianluca, Shu, Xiao-Ou, Visvanathan, Kala, White, Emily, Wolk, Alicja, Zeleniuch-Jacquotte, Anne, Zheng, Wei, Silverman, Debra T, Kogevinas, Manolis, Gonzalez, Juan R, Villa, Olaya, Li, Donghui, Duell, Eric J, Risch, Harvey A, Olson, Sara H, Kooperberg, Charles, Wolpin, Brian M, Jiao, Li, Hassan, Manal, Wheeler, William, Arslan, Alan A, Bas Bueno-de-Mesquita, H, Fuchs, Charles S, Gallinger, Steven, Gross, Myron D, Holly, Elizabeth A, Klein, Alison P, LaCroix, Andrea, Mandelson, Margaret T, Petersen, Gloria, Boutron-Ruault, Marie-Christine, Bracci, Paige M, Canzian, Federico, Chang, Kenneth, Cotterchio, Michelle, Giovannucci, Edward L, Goggins, Michael, Bolton, Judith A Hoffman, Jenab, Mazda, Khaw, Kay-Tee, Krogh, Vittorio, Kurtz, Robert C, McWilliams, Robert R, Mendelsohn, Julie B, Rabe, Kari G, Riboli, Elio, Tjønneland, Anne, Tobias, Geoffrey S, Trichopoulos, Dimitrios, Elena, Joanne W, Yu, Herbert, Amundadottir, Laufey, Stolzenberg-Solomon, Rachael Z, Kraft, Peter, Schumacher, Fredrick, Stram, Daniel, Savage, Sharon A, Mirabello, Lisa, Andrulis, Irene L, Wunder, Jay S, García, Ana Patiño, Sierrasesúmaga, Luis, Barkauskas, Donald A, Gorlick, Richard G, Purdue, Mark, Chow, Wong-Ho, Moore, Lee E, Schwartz, Kendra L, Davis, Faith G, Hsing, Ann W, Berndt, Sonja I, Black, Amanda, Wentzensen, Nicolas, Brinton, Louise A, Lissowska, Jolanta, Peplonska, Beata, McGlynn, Katherine A, Cook, Michael B, Graubard, Barry I, Kratz, Christian P, Greene, Mark H, Erickson, Ralph L, Hunter, David J, Thomas, Gilles, Hoover, Robert N, Real, Francisco X, Fraumeni, Joseph F, Caporaso, Neil E, Tucker, Margaret, Rothman, Nathaniel, Pérez-Jurado, Luis A, Chanock, Stephen J
    Publicado 2012
    “…In an analysis of 31,717 cancer cases and 26,136 cancer-free controls drawn from 13 genome-wide association studies (GWAS), we observed large chromosomal abnormalities in a subset of clones from DNA obtained from blood or buccal samples. …”
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    Detectable clonal mosaicism and its relationship to aging and cancer
  10. 1269710
    por Vimaleswaran, Karani S, Cavadino, Alana, Berry, Diane J, Jorde, Rolf, Dieffenbach, Aida Karina, Lu, Chen, Alves, Alexessander Couto, Heerspink, Hiddo J Lambers, Tikkanen, Emmi, Eriksson, Joel, Wong, Andrew, Mangino, Massimo, Jablonski, Kathleen A, Nolte, Ilja M, Houston, Denise K, Ahluwalia, Tarunveer Singh, van der Most, Peter J, Pasko, Dorota, Zgaga, Lina, Thiering, Elisabeth, Vitart, Veronique, Fraser, Ross M, Huffman, Jennifer E, de Boer, Rudolf A, Schöttker, Ben, Saum, Kai-Uwe, McCarthy, Mark I, Dupuis, Josée, Herzig, Karl-Heinz, Sebert, Sylvain, Pouta, Anneli, Laitinen, Jaana, Kleber, Marcus E, Navis, Gerjan, Lorentzon, Mattias, Jameson, Karen, Arden, Nigel, Cooper, Jackie A, Acharya, Jayshree, Hardy, Rebecca, Raitakari, Olli, Ripatti, Samuli, Billings, Liana K, Lahti, Jari, Osmond, Clive, Penninx, Brenda W, Rejnmark, Lars, Lohman, Kurt K, Paternoster, Lavinia, Stolk, Ronald P, Hernandez, Dena G, Byberg, Liisa, Hagström, Emil, Melhus, Håkan, Ingelsson, Erik, Mellström, Dan, Ljunggren, Östen, Tzoulaki, Ioanna, McLachlan, Stela, Theodoratou, Evropi, Tiesler, Carla M T, Jula, Antti, Navarro, Pau, Wright, Alan F, Polasek, Ozren, Hayward, Caroline, Wilson, James F, Rudan, Igor, Salomaa, Veikko, Heinrich, Joachim, Campbell, Harry, Price, Jacqueline F, Karlsson, Magnus, Lind, Lars, Michaëlsson, Karl, Bandinelli, Stefania, Frayling, Timothy M, Hartman, Catharina A, Sørensen, Thorkild I A, Kritchevsky, Stephen B, Langdahl, Bente Lomholt, Eriksson, Johan G, Florez, Jose C, Spector, Tim D, Lehtimäki, Terho, Kuh, Diana, Humphries, Steve E, Cooper, Cyrus, Ohlsson, Claes, März, Winfried, de Borst, Martin H, Kumari, Meena, Kivimaki, Mika, Wang, Thomas J, Power, Chris, Brenner, Hermann, Grimnes, Guri, van der Harst, Pim, Snieder, Harold, Hingorani, Aroon D, Pilz, Stefan, Whittaker, John C, Järvelin, Marjo-Riitta, Hyppönen, Elina
    Publicado 2014
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    Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study
  11. 1269711
    por Azmil, Ameerah Mohd, Bansal, Gaurav Jyoti, Davies, Eleri, Wallis, Matthew, Kilburn-Toppin, Fleur, Taylor-Phillip, Sian, Buckley, Anne, Healy, Nuala, Quinn, Aine, O’Keeffe, Sylvia, Ang, Teri, Maxwell, Anthony, Lim, Yit Y., Harkness, Elaine, Emsley, Richard, Astley, Susan, Gadde, Soujanya, Ang, Teri, Maxwell, Anthony, Lim, Yit Y., Harkness, Elaine, Emsley, Richard, Astley, Susan, Gadde, Soujanya, Ferguson, Jennifer, Stevens, Guy, Hills, Robert, Thomas, Kate Gower, Rajan, Sabrina, Sharma, Nisha, Kishore, Ajit, O’ Dowd, John, Murphy, Claire, Lindsay, Ken, Dadayal, Guneesh, Moody, Anne Nielsen, Whitaker, Madeleine, Wolstenhulme, Stephen, Bull, Jane, Sharma, Nisha, Culpan, Anne-Marie, Roszkowski, Natalia, Grima, Alexis, Stahnke, Michaela, Rubin, Caroline, Walker, Ruth, Oeppen, Rachel, Puttagunta, Srikanth, Gray, Karen, Puri, Shama, Sharma, Nisha, Millican-Slater, Rebecca, Pascaline, Sana, Hajaj, Mohamad, Flinn, Janet, Thomson, Kim, Elsberger, Beatrix, Turnbull, Anne, Bagnall, Mark, York, Joanne, Benney, Stuart, Goyal, Amit, Topps, Ashley, Barr, Simon, Pikoulas, Panagiotis, Pritchard, Susan, Maxwell, Anthony, Greenhalgh, Sophie, Sreenivas, Muthyala, Greenhalgh, Sophie, Sreenivas, Muthyala, Greenhalgh, Sophie, Sreenivas, Muthyala, Nandhra, Anju, Sharma, Sheetal, Gulati, Archita, Razzaq, Furhan, Khan, Sana, McKillen, Jacqueline, Larkin, Rupert, Sreenivas, Muthyala, Kamat, Sachin, Goncalves, Carla, Tan, Alan, Eleti, Asha, Vidyaprakash, Nithya, McMahon, Michelle A., Dall, Barbara J. G., Sharma, Nisha, Majid, Faisal, Sreenivas, Muthyala, Rattehalli, Ramachadra, Gaur, Vandana, Mackenzie, Alistair, Warren, Lucy, Patel, Mishal, Halling-Brown, Mark, Wilkinson, Louise, Young, Kenneth, Tanner, James, Wallis, Matthew, Currie, Rachael, Balyes, Sharron, Wragg, Julie, Zamfir, Georgiana, Ayra, Pallavi, Marsden, Max, Butterworth, James, Sinha, Shona, Desai, Anil, Metafa, Anna, Whitaker, Madeleine, Nielsen-Moody, Anne, Wolstenhulme, Stephen, Sharma, Nisha, Bull, Jane, Ward, Laura, Heller, Samantha, Hudson, Sue, Wilkinson, Louise, Taylor, Kathryn, Xyda, Argyro, Turnbull, Anne, Allen, Steven, Orlowski, Elizabeth, York, Joanne, Downey, Kate, Sidebottom, Richard, Wallis, Matthew, Lodhi, Ahmad, Harkness, Elaine, Maxwell, Anthony, Howell, Anthony, Evans, Gareth, Gadde, Soujanya, Astley, Susan, Lim, Yit, Chen, Yan, Lepine-Williams, Elizabeth, Henderson, Steven, Litherland, Janet, Altaf, Naveed, Bury, Yvonne, Forester, Nerys, Chin, Mei Chan, Litherland, Janet, Taylor, Caroline, Skippage, Pippa, Sian, Aneet, McAvinchey, Rita, Evans, Tom, Stevens, Guy, Nisbet, Sian, Murray, Alex, Thomas, Kate Gower, Castillo, Raquel Clark, Markham, Hannah, Oeppen, Rachel, Thomas, Timothy, Jain, Anil, Molderson, Jaanilka, Wan, Joseph, Newman, Helen, Lowes, Simon, Lunt, Linsley, Sultana, Sadia, Chillal, Varun, Sreenivas, Muthyala, Dalton, Rebecca, Reeves, David, Sergeant, Jamie, Harkness, Elaine, Gadde, Soujanya, Maxwell, Anthony, Lim, Yit, Astley, Susan, Edwards, Liz, Jenkins, Kate, Stevens, Guy, Jain, Anil, Molderson, Jaanilka, Shaikh, Shaheeda, Sidebottom, Richard, O’Flynn, Elizabeth, Bombroffe, Laura, Hughes, Julie, Scurr, Erica, Wilson, Robin, Jones, Lyn, Govindarajulu, Sasirekha, Sahu, Ajay K., Brown, Matthew, Allen, Steve, O’Flynn, Liz, deSouza, Nandita, Rahim, Rumana, Wasan, Rema, Goligher, Jane, Wijesuriya, Shalini, Morel, Juliet, Peacock, Clare, Michell, Michael, Iqbal, Asif, Evans, David, Batohi, Bhavna, Wasan, Tavleen, Phillips, Vivien, Manuel, Eden, Bowman, Gillian, Satchithananda, Keshthra, Batohi, Bhavna, Fang, Cheng, Michell, Michael, Morel, Juliet, Shah, Chirag, Wijesuriya, Shalini, Peacock, Clare, Rahim, Rumana, Wasan, Rema, Goligher, Jane, Satchithananda, Keshthra, Altaf, Naveed, Forester, Nerys, Hodkin, Leanne, Horgan, Keiran, Dodwell, David, Sharma, Nisha, Moloney, BM, Casey, M. C., Breathnach, A., Dwyer, R. M., McLoughlin, R., Sweeney, K. J., Malone, C., Healy, M. J., Kerin, M. J., Forester, Nerys, Lowes, Simon, Mitchell, Elizabeth, Twiddy, Maureen, Maxwell, Anthony, Sharma, Nisha, Dobson, Hilary, Vinnicombe, Sarah, Evans, Andrew, Grant, David, Bishop, Briony, Giggens, Roxanne, Bhuva, Shaheel, Royds, Jennifer, Camilleri, Francesca, Babu, Gauripriya, Beveridge, Carolyn, Geach, Rebecca, Klimczak, Katherine, Massey, Helen, Lyburn, Iain, Wan, Joseph, Jain, Anil, Molderson, Jaanilka, Salehi-Bird, Seema, Nishtala, Sahithi, Gunning, Liz, Changaradil, Deepthi Vinayan, Bansal, Jyoti, Davis, Joanna, Sharma, Ashwini, Del Voscovo, Elena, Etheridge, Harriet, Butler, Aisling, Fenne, David S. J., Rubin, Gary, Burt, Helen, Ridley, Nick, Taylor, Sarah, Sreenivas, Muthyala, Seth, Subodh, Seth, Archana
    Publicado 2016
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    British Society of Breast Radiology Annual Scientific Meeting 2016: Manchester, UK. 6-8 November 2016
  12. 1269712
    por Nolte, Ilja M., Munoz, M. Loretto, Tragante, Vinicius, Amare, Azmeraw T., Jansen, Rick, Vaez, Ahmad, von der Heyde, Benedikt, Avery, Christy L., Bis, Joshua C., Dierckx, Bram, van Dongen, Jenny, Gogarten, Stephanie M., Goyette, Philippe, Hernesniemi, Jussi, Huikari, Ville, Hwang, Shih-Jen, Jaju, Deepali, Kerr, Kathleen F., Kluttig, Alexander, Krijthe, Bouwe P., Kumar, Jitender, van der Laan, Sander W., Lyytikäinen, Leo-Pekka, Maihofer, Adam X., Minassian, Arpi, van der Most, Peter J., Müller-Nurasyid, Martina, Nivard, Michel, Salvi, Erika, Stewart, James D., Thayer, Julian F., Verweij, Niek, Wong, Andrew, Zabaneh, Delilah, Zafarmand, Mohammad H., Abdellaoui, Abdel, Albarwani, Sulayma, Albert, Christine, Alonso, Alvaro, Ashar, Foram, Auvinen, Juha, Axelsson, Tomas, Baker, Dewleen G., de Bakker, Paul I. W., Barcella, Matteo, Bayoumi, Riad, Bieringa, Rob J., Boomsma, Dorret, Boucher, Gabrielle, Britton, Annie R., Christophersen, Ingrid, Dietrich, Andrea, Ehret, George B., Ellinor, Patrick T., Eskola, Markku, Felix, Janine F., Floras, John S., Franco, Oscar H., Friberg, Peter, Gademan, Maaike G. J., Geyer, Mark A., Giedraitis, Vilmantas, Hartman, Catharina A., Hemerich, Daiane, Hofman, Albert, Hottenga, Jouke-Jan, Huikuri, Heikki, Hutri-Kähönen, Nina, Jouven, Xavier, Junttila, Juhani, Juonala, Markus, Kiviniemi, Antti M., Kors, Jan A., Kumari, Meena, Kuznetsova, Tatiana, Laurie, Cathy C., Lefrandt, Joop D., Li, Yong, Li, Yun, Liao, Duanping, Limacher, Marian C., Lin, Henry J., Lindgren, Cecilia M., Lubitz, Steven A., Mahajan, Anubha, McKnight, Barbara, zu Schwabedissen, Henriette Meyer, Milaneschi, Yuri, Mononen, Nina, Morris, Andrew P., Nalls, Mike A., Navis, Gerjan, Neijts, Melanie, Nikus, Kjell, North, Kari E., O'Connor, Daniel T., Ormel, Johan, Perz, Siegfried, Peters, Annette, Psaty, Bruce M., Raitakari, Olli T., Risbrough, Victoria B., Sinner, Moritz F., Siscovick, David, Smit, Johannes H., Smith, Nicholas L., Soliman, Elsayed Z., Sotoodehnia, Nona, Staessen, Jan A., Stein, Phyllis K., Stilp, Adrienne M., Stolarz-Skrzypek, Katarzyna, Strauch, Konstantin, Sundström, Johan, Swenne, Cees A., Syvänen, Ann-Christine, Tardif, Jean-Claude, Taylor, Kent D., Teumer, Alexander, Thornton, Timothy A., Tinker, Lesley E., Uitterlinden, André G., van Setten, Jessica, Voss, Andreas, Waldenberger, Melanie, Wilhelmsen, Kirk C., Willemsen, Gonneke, Wong, Quenna, Zhang, Zhu-Ming, Zonderman, Alan B., Cusi, Daniele, Evans, Michele K., Greiser, Halina K., van der Harst, Pim, Hassan, Mohammad, Ingelsson, Erik, Järvelin, Marjo-Riitta, Kääb, Stefan, Kähönen, Mika, Kivimaki, Mika, Kooperberg, Charles, Kuh, Diana, Lehtimäki, Terho, Lind, Lars, Nievergelt, Caroline M., O'Donnell, Chris J., Oldehinkel, Albertine J., Penninx, Brenda, Reiner, Alexander P., Riese, Harriëtte, van Roon, Arie M., Rioux, John D., Rotter, Jerome I., Sofer, Tamar, Stricker, Bruno H., Tiemeier, Henning, Vrijkotte, Tanja G. M., Asselbergs, Folkert W., Brundel, Bianca J. J. M., Heckbert, Susan R., Whitsel, Eric A., den Hoed, Marcel, Snieder, Harold, de Geus, Eco J. C.
    Publicado 2017
    “…In two-stage meta-analyses of genome-wide association studies for three HRV traits in up to 53,174 individuals of European ancestry, we detect 17 genome-wide significant SNPs in eight loci. …”
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    Genetic loci associated with heart rate variability and their effects on cardiac disease risk
  13. 1269713
    “…The primary endpoint was overall survival, analysed in the intention-to-treat population, using a two-stage meta-analysis of pooled individual patient data. All three trials have completed 2 years of follow-up. …”
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    First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials
  14. 1269714
    por Galluzzi, Lorenzo, Vitale, Ilio, Aaronson, Stuart A., Abrams, John M., Adam, Dieter, Agostinis, Patrizia, Alnemri, Emad S., Altucci, Lucia, Amelio, Ivano, Andrews, David W., Annicchiarico-Petruzzelli, Margherita, Antonov, Alexey V., Arama, Eli, Baehrecke, Eric H., Barlev, Nickolai A., Bazan, Nicolas G., Bernassola, Francesca, Bertrand, Mathieu J. M., Bianchi, Katiuscia, Blagosklonny, Mikhail V., Blomgren, Klas, Borner, Christoph, Boya, Patricia, Brenner, Catherine, Campanella, Michelangelo, Candi, Eleonora, Carmona-Gutierrez, Didac, Cecconi, Francesco, Chan, Francis K.-M., Chandel, Navdeep S., Cheng, Emily H., Chipuk, Jerry E., Cidlowski, John A., Ciechanover, Aaron, Cohen, Gerald M., Conrad, Marcus, Cubillos-Ruiz, Juan R., Czabotar, Peter E., D’Angiolella, Vincenzo, Dawson, Ted M., Dawson, Valina L., De Laurenzi, Vincenzo, De Maria, Ruggero, Debatin, Klaus-Michael, DeBerardinis, Ralph J., Deshmukh, Mohanish, Di Daniele, Nicola, Di Virgilio, Francesco, Dixit, Vishva M., Dixon, Scott J., Duckett, Colin S., Dynlacht, Brian D., El-Deiry, Wafik S., Elrod, John W., Fimia, Gian Maria, Fulda, Simone, García-Sáez, Ana J., Garg, Abhishek D., Garrido, Carmen, Gavathiotis, Evripidis, Golstein, Pierre, Gottlieb, Eyal, Green, Douglas R., Greene, Lloyd A., Gronemeyer, Hinrich, Gross, Atan, Hajnoczky, Gyorgy, Hardwick, J. Marie, Harris, Isaac S., Hengartner, Michael O., Hetz, Claudio, Ichijo, Hidenori, Jäättelä, Marja, Joseph, Bertrand, Jost, Philipp J., Juin, Philippe P., Kaiser, William J., Karin, Michael, Kaufmann, Thomas, Kepp, Oliver, Kimchi, Adi, Kitsis, Richard N., Klionsky, Daniel J., Knight, Richard A., Kumar, Sharad, Lee, Sam W., Lemasters, John J., Levine, Beth, Linkermann, Andreas, Lipton, Stuart A., Lockshin, Richard A., López-Otín, Carlos, Lowe, Scott W., Luedde, Tom, Lugli, Enrico, MacFarlane, Marion, Madeo, Frank, Malewicz, Michal, Malorni, Walter, Manic, Gwenola, Marine, Jean-Christophe, Martin, Seamus J., Martinou, Jean-Claude, Medema, Jan Paul, Mehlen, Patrick, Meier, Pascal, Melino, Sonia, Miao, Edward A., Molkentin, Jeffery D., Moll, Ute M., Muñoz-Pinedo, Cristina, Nagata, Shigekazu, Nuñez, Gabriel, Oberst, Andrew, Oren, Moshe, Overholtzer, Michael, Pagano, Michele, Panaretakis, Theocharis, Pasparakis, Manolis, Penninger, Josef M., Pereira, David M., Pervaiz, Shazib, Peter, Marcus E., Piacentini, Mauro, Pinton, Paolo, Prehn, Jochen H.M., Puthalakath, Hamsa, Rabinovich, Gabriel A., Rehm, Markus, Rizzuto, Rosario, Rodrigues, Cecilia M.P., Rubinsztein, David C., Rudel, Thomas, Ryan, Kevin M., Sayan, Emre, Scorrano, Luca, Shao, Feng, Shi, Yufang, Silke, John, Simon, Hans-Uwe, Sistigu, Antonella, Stockwell, Brent R., Strasser, Andreas, Szabadkai, Gyorgy, Tait, Stephen W.G., Tang, Daolin, Tavernarakis, Nektarios, Thorburn, Andrew, Tsujimoto, Yoshihide, Turk, Boris, Vanden Berghe, Tom, Vandenabeele, Peter, Vander Heiden, Matthew G., Villunger, Andreas, Virgin, Herbert W., Vousden, Karen H., Vucic, Domagoj, Wagner, Erwin F., Walczak, Henning, Wallach, David, Wang, Ying, Wells, James A., Wood, Will, Yuan, Junying, Zakeri, Zahra, Zhivotovsky, Boris, Zitvogel, Laurence, Melino, Gerry, Kroemer, Guido
    Publicado 2018
    “…The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field.…”
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    Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
  15. 1269715
    “…In this complex context, the meaningful engagement and reflection of program staff and collaborators is essential for all aspects of program planning, implementation, reporting, and dissemination. …”
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    3402 A High-Impact, Structured, Collaborative Approach to Implementing and Utilizing the Research Performance Progress Report (RPPR) for a Clinical and Translational Science Award
  16. 1269716
    “…We used two-way ANOVA with Bonferroni’s post-hoc test to analyse autoradiography and SV2A immunostaining data, and the Kruskal-Wallis test, with alpha=0.05, to analyse western blot data. …”
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    O11.3. SYNAPTIC MARKER PROTEIN SV2A IS REDUCED IN SCHIZOPHRENIA IN VIVO AND UNAFFECTED BY ANTIPSYCHOTICS IN RATS
  17. 1269717
    por Duclos, Antoine, Chollet, François, Pascal, Léa, Ormando, Hector, Carty, Matthew J, Polazzi, Stéphanie, Lifante, Jean-Christophe, Bourgoin, Françoise, Holla, Housseyni, Steunou, Sandra, Naudot, Clotilde, Lacombe, Isabelle, Lefevre, Jérémie, Carty, Matthew J, Arimont, Jean-Marc, Foulkes, Charles, David, Patrice, Neyer, Laurence, Gayet, Clément, Hemet, Sandrine, Le Menn, Loïc, Serra-Maudet, Valérie, Abet, Emeric, Poussier, Matthieu, Broli, Jérôme, Papaleo, Domenico, Proske, Jan Martin, Filippi, Valérie, Mazza, Davide, Fraleu Louër, Bénédicte, Gratien, Dominique, Poirier, Hélène, Alves-Neto, Béatrice, Fixot, Kévin, Hournau, Matthieu, Regimbeau, Jean-Marc, Bouviez, Nicolas, Marion, Yoann, Dubois, Anne, Perret-Boire, Sophie, Pezet, Denis, Mariette, Christophe, Brunaud, Laurent, Germain, Adeline, Podevin, Juliette, Riegler, Edwige, Debs, Tarek, Gauzolino, Riccardo, Kianmanesh, Reza, Brek, Amine, Kirzin, Sylvain, Bourdet, Benoît, Suc, Bertrand, Brachet, Dorothée, Cojocarasu, Dumitru, Granger, Philippe, Bageacu, Serban, Bourbon, Michel, Bertolaso, Walter, Caillon, Pierre, Ormando, Hector, Lupinacci, Renato, Oberlin, Olivier, Champault, Axèle, Sigismond, Monique, Frileux, Pascal, Rault, Alexandre, Bourdariat, Raphaël, Lamblin, Antoine, Leclercq, Christine, Pol, Bernard, Adam, Mathilde, Poncet, Gilles, Valette-Lagnel, Catherine, Chollet, François, Colin, Cyrille, Duclos, Antoine, Mensah, Keitly, Michel, Philippe, Pascal, Léa, Payet, Cécile, Polazzi, Stéphanie, Couraud, Sébastien, Lifante, Jean-Christophe, Passot, Guillaume, Peix, Jean-Louis, Piriou, Vincent, Beau, Cédric, Benand, Philippe, Brugiere, Benjamin, Koriche, Dine
    Publicado 2020
    “…Among the intervention hospitals, the effect size was proportional to the degree of control chart implementation witnessed. Highly compliant hospitals experienced a more important reduction in major adverse events (0.84, 0.77 to 0.92), patient death (0.78, 0.63 to 0.97), intensive care stay (0.76, 0.67 to 0.87), and reoperation (0.84, 0.74 to 0.96). …”
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    Effect of monitoring surgical outcomes using control charts to reduce major adverse events in patients: cluster randomised trial
  18. 1269718
    por Abba, A., Accorsi, C., Agnes, P., Alessi, E., Amaudruz, P., Annovi, A., Desages, F. Ardellier, Back, S., Badia, C., Bagger, J., Basile, V., Batignani, G., Bayo, A., Bell, B., Beschi, M., Biagini, D., Bianchi, G., Bicelli, S., Bishop, D., Boccali, T., Bombarda, A., Bonfanti, S., Bonivento, W. M., Bouchard, M., Breviario, M., Brice, S., Brown, R., Calvo-Mozota, J. M., Camozzi, L., Camozzi, M., Capra, A., Caravati, M., Carlini, M., Ceccanti, A., Celano, B., Cela Ruiz, J. M., Charette, C., Cogliati, G., Constable, M., Crippa, C., Croci, G., Cudmore, S., Dahl, C. E., Dal Molin, A., Daley, M., Di Guardo, C., D'Avenio, G., Davignon, O., Del Tutto, M., De Ruiter, J., Devoto, A., Diaz Gomez Maqueo, P., Di Francesco, F., Dossi, M., Druszkiewicz, E., Duma, C., Elliott, E., Farina, D., Fernandes, C., Ferroni, F., Finocchiaro, G., Fiorillo, G., Ford, R., Foti, G., Fournier, R. D., Franco, D., Fricbergs, C., Gabriele, F., Galbiati, C., Garcia Abia, P., Gargantini, A., Giacomelli, L., Giacomini, F., Giacomini, F., Giarratana, L. S., Gillespie, S., Giorgi, D., Girma, T., Gobui, R., Goeldi, D., Golf, F., Gorel, P., Gorini, G., Gramellini, E., Grosso, G., Guescini, F., Guetre, E., Hackman, G., Hadden, T., Hawkins, W., Hayashi, K., Heavey, A., Hersak, G., Hessey, N., Hockin, G., Hudson, K., Ianni, A., Ienzi, C., Ippolito, V., James, C. C., Jillings, C., Kendziora, C., Khan, S., Kim, E., King, M., King, S., Kittmer, A., Kochanek, I., Kowalkowski, J., Krücken, R., Kushoro, M., Kuula, S., Laclaustra, M., Leblond, G., Lee, L., Lennarz, A., Leyton, M., Li, X., Liimatainen, P., Lim, C., Lindner, T., Lomonaco, T., Lu, P., Lubna, R., Lukhanin, G. A., Luzón, G., MacDonald, M., Magni, G., Maharaj, R., Manni, S., Mapelli, C., Margetak, P., Martin, L., Martin, S., Martínez, M., Massacret, N., McClurg, P., McDonald, A. B., Meazzi, E., Migalla, R., Mohayai, T., Tosatti, L. M., Monzani, G., Moretti, C., Morrison, B., Mountaniol, M., Muraro, A., Napoli, P., Nati, F., Natzke, C. R., Noble, A. J., Norrick, A., Olchanski, K., Ortiz de Solorzano, A., Padula, F., Pallavicini, M., Palumbo, I., Panontin, E., Papini, N., Parmeggiano, L., Parmeggiano, S., Patel, K., Patel, A., Paterno, M., Pellegrino, C., Pelliccione, P., Pesudo, V., Pocar, A., Pope, A., Pordes, S., Prelz, F., Putignano, O., Raaf, J. L., Ratti, C., Razeti, M., Razeto, A., Reed, D., Refsgaard, J., Reilly, T., Renshaw, A., Retriere, F., Riccobene, E., Rigamonti, D., Rizzi, A., Rode, J., Romualdez, J., Russel, L., Sablone, D., Sala, S., Salomoni, D., Salvo, P., Sandoval, A., Sansoucy, E., Santorelli, R., Savarese, C., Scapparone, E., Schaubel, T., Scorza, S., Settimo, M., Shaw, B., Shawyer, S., Sher, A., Shi, A., Skensved, P., Slutsky, A., Smith, B., Smith, N. J. T., Stenzler, A., Straubel, C., Stringari, P., Suchenek, M., Sur, B., Tacchino, S., Takeuchi, L., Tardocchi, M., Tartaglia, R., Thomas, E., Trask, D., Tseng, J., Tseng, L., VanPagee, L., Vedia, V., Velghe, B., Viel, S., Visioli, A., Viviani, L., Vonica, D., Wada, M., Walter, D., Wang, H., Wang, M. H. L. S., Westerdale, S., Wood, D., Yates, D., Yue, S., Zambrano, V.
    Publicado 2021
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    The novel Mechanical Ventilator Milano for the COVID-19 pandemic
  19. 1269719
    “…Ce qui indique qu’il faudrait tenir compte de l’apport de la démographie en santé environnementale. …”
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    COVID-19 et Système d’information géographique comme outil de recherche épidémiologique au Maroc
  20. 1269720
    “…MÉTHODES: Cette étude observationnelle et transversale a été menée sous forme d’un questionnaire en ligne accessible sur Carenity, une communauté de patients en ligne, du 3 juin 2020 au 7 octobre 2020. Elle concernait les patients adultes français vivant avec une MC. …”
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    Impact post-déconfinement de la pandémie de COVID-19 sur les patients chroniques en France
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