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1269921por Xu, Yan, Xiong, Yilin, Liu, Ying, Li, Gangping, Bai, Tao, Zheng, Gen, Hou, Xiaohua, Song, Jun“…Piezo1 flox-mucin2 Cre mice showed decreased mucus expression and increased methylation compared to wild-type mice. Cell experiments showed that mechanical stimulation induced the activation of Piezo1, decreased H3K9me3 and SUV39h1, and upregulated mucin2 expression. …”
Publicado 2023
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1269922por Savona, Michael R., McCloskey, James K., Griffiths, Elizabeth A., Yee, Karen W.L., Al-Kali, Aref, Zeidan, Amer M., Deeg, H. Joachim, Patel, Prapti A., Sabloff, Mitchell, Keating, Mary-Margaret, Dao, Kim-Hien, Zhu, Nancy, Gabrail, Nashat, Fazal, Salman, Maly, Joseph, Odenike, Olatoyosi, Kantarjian, Hagop M., DeZern, Amy E., O'Connell, Casey L., Roboz, Gail J., Busque, Lambert, Wells, Richard A., Amin, Harshad, Randhawa, Jasleen K., Leber, Brian, Hao, Yong, Keer, Harold N., Azab, Mohammad, Garcia-Manero, Guillermo“…Cycles were repeated every 28 days. All patients received oral decitabine/cedazuridine in all subsequent cycles from Cycle 3 onwards until disease progression or unacceptable toxicity. …”
Publicado 2020
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1269923por Merid, Yared, Tekleselasie, Wondwosen, Tesfaye, Emnet, Gadisa, Anteneh, Fentahun, Dessalegn, Abate, Alegntaw, Alemu, Aynalem, Mihret, Adane, Mulu, Andargachew, Gelanew, Tesfaye“…In addition, we measured and compared the levels of binding IgA antibodies to spike RBD of SARS-CoV-2 Wild type, Delta, and Omicron variants in a small subset of unvaccinated and BNT-vaccinated schoolchildren. …”
Publicado 2023
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1269924por Lorza-Gil, Estela, Kaiser, Gabriele, Carlein, Christopher, Hoffmann, Markus D. A., König, Gabriele M., Haug, Sieglinde, Prates Roma, Leticia, Rexen Ulven, Elisabeth, Ulven, Trond, Kostenis, Evi, Birkenfeld, Andreas L., Häring, Hans-Ulrich, Ullrich, Susanne, Gerst, Felicia“…Although NEFA are major components of breastmilk and insulin secretagogues, their role for functional maturation of neonatal beta cells is still unclear. NEFA are the endogenous ligands of fatty acid receptor 1 (FFA1, encoded by Ffar1 in mice), a Gq-coupled receptor with stimulatory effect on insulin secretion. …”
Publicado 2023
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1269925por Aboukheir Aboukheir, Aihab, Villanueva, Emilio Q., Garrett, Joseph R., Moodie, Carla C., Tew, Jenna R., Toloza, Eric M., Fontaine, Jacques P., Baldonado, Jobelle J. A. R.“…Numerical variables were described as the median and interquartile range because all numerical variables were not normally distributed as assessed by the Shapiro–Wilk test of normality. …”
Publicado 2023
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1269926por Krahulec, Stefan, Petschacher, Barbara, Wallner, Michael, Longus, Karin, Klimacek, Mario, Nidetzky, Bernd“…RESULTS: BP10001 and BP000, expressing C. tenuis xylose reductase in NADPH-preferring wild-type form, were used. Glucose and xylose (each at 10 g/L) were converted sequentially, the corresponding q(substrate )values being similar for each strain (glucose: 3.0; xylose: 0.05). …”
Publicado 2010
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1269927“…The standard for allowable radioactive cesium (Cs-134 and Cs-137) of 100 Bq/Kg in general food, 50 Bq/Kg in infant formula and all milk products, and 10 Bq/Kg in drinking water was enforced from April 2012 under the Food Sanitation Law, although a provisional standard on radio-contamination had been applied since the nuclear accident. …”
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1269928por Yuan, Guo-Qiang, Gao, Song, Geng, Yong-Jian, Tang, Yao-Ping, Zheng, Min-Juan, Shelat, Harnath S, Collins, Scott, Wu, Han-Jing, Wu, Yi-Ling“…METHODS: After intragastric administration of TXL (0.1 ml/10 g body weight) to C57BL/6J wild-type mice (n = 8) and ApoE-/- mice (n = 8), total cholesterol, high-density lipoprotein-cholesterol, very-low-density lipoprotein (VLDL)-cholesterol, triglyceride, and blood glucose levels in serum were measured. …”
Publicado 2018
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1269929“…Quantitative real-time polymerase chain reaction (qRT-PCR) was used to detect cell proliferation/cell cycle-related gene expression in cardiac tissue. …”
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1269930por Rajendra, Shanmugarajah, Xuan, Wei, Merrett, Neil, Sharma, Preeti, Sharma, Prateek, Pavey, Darren, Yang, Tao, Santos, Leonardo D., Sharaiha, Omar, Pande, Girish, Cosman, Peter, Wu, Xiaojuan, Wang, Bin“…Patients who were HPV positive mostly had high p16(INK4A) expression, low p53 expression, and wild-type TP53. There were more Tis, T1, and T2 tumors in HPV-positive patients compared with HPV-negative patients (75.7% vs 54.3%; difference, 21.4%; 95% CI, 4.6%-38.2%; P = .02). …”
Publicado 2018
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1269931por Fernandez-Mosquera, Lorena, Yambire, King Faisal, Couto, Renata, Pereyra, Leonardo, Pabis, Kamil, Ponsford, Amy H., Diogo, Cátia V., Stagi, Massimiliano, Milosevic, Ira, Raimundo, Nuno“…Mitochondria are key organelles for cellular metabolism, and regulate several processes including cell death and macroautophagy/autophagy. Here, we show that mitochondrial respiratory chain (RC) deficiency deactivates AMP-activated protein kinase (AMPK, a key regulator of energy homeostasis) signaling in tissue and in cultured cells. …”
Publicado 2019
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1269932por Peltonen, Teemu, Mustonen, Antti, Koskela, Jari, Miettunen, Jouko, Veijola, Juha, Niemelä, Solja“…METHODS: The Northern Finland Birth Cohort 1986 study includes 99% of all births (n=9432) in the region. At age 15–16, data on self-reported daily cigarette smoking and cannabis use was gathered using questionnaires. …”
Publicado 2020
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1269933“…The bulk Cu isotopic compositions, expressed as δ(65)Cu(SRM976) in per mil (‰) relative to NIST SRM976 with combined uncertainties (U, k = 2), of SSC-1, SSC-3 and SSC-4, determined utilizing SN-MC-ICP-MS, are identical within analytical uncertainty at 0.03 ± 0.07‰ (n = 29), 0.04 ± 0.04‰ (n = 28), and 0.05 ± 0.08‰ (n = 29), respectively; the composition of CUPD-1 is 2.14 ± 0.08‰ (n = 28). …”
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1269934por Tumwebaze, Patrick K, Katairo, Thomas, Okitwi, Martin, Byaruhanga, Oswald, Orena, Stephen, Asua, Victor, Duvalsaint, Marvin, Legac, Jennifer, Chelebieva, Sevil, Ceja, Frida G, Rasmussen, Stephanie A, Conrad, Melissa D, Nsobya, Samuel L, Aydemir, Ozkan, Bailey, Jeffrey A, Bayles, Brett R, Rosenthal, Philip J, Cooper, Roland A“…METHODS: In this prospective longitudinal study, P falciparum isolates were collected from patients aged 6 months or older presenting at the Tororo District Hospital (Tororo district, a site with relatively low malaria incidence) or Masafu General Hospital (Busia district, a high-incidence site) in eastern Uganda with clinical symptoms of malaria, a positive Giemsa-stained blood film for P falciparum, and no signs of severe disease. …”
Publicado 2021
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1269935por Eriksson, L. S. E., Nastic, D., Lindqvist, P. G., Imboden, S., Järnbert‐Pettersson, H., Carlson, J. W., Epstein, E.“…In addition, molecular analysis was performed for classification into the four ProMisE subtypes: polymerase‐ϵ exonuclease domain mutations (POLE EDM), mismatch repair proteins deficiency (MMR‐D), protein 53 wild type (p53 wt) and protein 53 abnormal (p53 abn). …”
Publicado 2021
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1269936por Meyers, Michael“…Data were subject to multivariate analyses of variance (MANOVA) and Wilks’ λ criteria using general linear model procedures. …”
Publicado 2021
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1269937por Lalevée, Matthieu, Mansur, Nacime S., Schmidt, Eli, Dibbern, Kevin N., Wagner, Emilio, Wagner, Pablo, Nery, Caio A., Lintz, Francois, Netto, Cesar de Cesar“…Normality was assessed using Shapiro-Wilk tests. Comparisons were made using Student tests for normal variables and Mann-Whitney for non-normals. …”
Publicado 2022
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1269938por Wang, Xiangyu, Guo, Xiaofei, He, Xiaoyun, Di, Ran, Zhang, Xiaosheng, Zhang, Jinlong, Chu, Mingxing“…Thus, we examined the abundance of hypothalamus tissue protein profiles of six FecB mutant homozygous (BB) and six wild-type (WW) ewes at the luteal and follicular phases. …”
Publicado 2022
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1269939
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1269940por Acciarri, R., Adams, C., An, R., Andreopoulos, C., Ankowski, A.M., Antonello, M., Asaadi, J., Hewes, J., Badgett, W., Bagby, L., Baibussinov, B., Baller, B., Barr, G., Barros, N., Bass, M., Bellini, V., Benetti, P., Bertolucci, S., Biery, K., Bilokon, H., Bishai, M., Bitadze, A., Blake, A., Boffelli, F., Bolton, T., Bonesini, M., Bremer, J., Brice, S.J., Bromberg, C., Bugel, L., Calligarich, E., Camilleri, L., Caratelli, D., Carls, B., Cavanna, F., Centro, S., Chen, H., Chi, C., Church, E., Cianci, D., Cocco, A.G., Collin, G.H., Conrad, J.M., Convery, M., De Geronimo, G., Dermenev, A., Dharmapalan, R., Dixon, S., Djurcic, Z., Dytmam, S., Eberly, B., Ereditato, A., Esquivel, J., Evans, J., Falcone, A., Farnese, C., Fava, A., Ferrari, A., Fleming, B.T., Foreman, W.M., Freestone, J., Gamble, T., Garvey, G., Genty, V., Geynisman, M., Gibin, D., Gninenko, S., Goldi, D., Gollapinni, S., Golubev, N., Graham, M., Gramellini, E., Greenlee, H., Grosso, R., Guenette, R., Guglielmi, A., Hackenburg, A., Hanni, R., Hen, O., Hewes, V., Ho, J., Horton-Smith, G., Howell, J., Ivashkin, A., James, C., Jen, C.M., Johnson, R.A., Jones, B.J.P., Joshi, J., Jostlein, H., Kaleko, D., Kalousis, L.N., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kirsanov, M., Kisiel, J., Klein, J., Klinger, J., Kobilarcik, T., Kose, U., Kreslo, I., Kudryavtsev, V.A., Li, Y., Littlejohn, B., Lissauer, D., Livesly, P., Lockwitz, S., Louis, W.C., Luthi, M., Lundberg, B., Mammoliti, F., Mannocchi, G., Marchionni, A., Mariani, C., Marshall, J., Mavrokoridis, K., McCauley, N., McConkey, N., McDonald, K., Meddage, V., Menegolli, A., Meng, G., Mercer, I., Miao, T., Miceli, T., Mills, G.B., Mladenov, D., Montanari, C., Montanari, D., Moon, J., Mooney, M., Moore, C., Moss, Z., Moulai, M.H., Mufson, S., Murrells, R., Naples, D., Nessi, M., Nicoletto, M., Nienaber, P., Norris, B., Noto, F., Nowak, J., Pal, S., Palamara, O., Paolone, V., Papavassiliou, V., Pate, S., Pater, J., Pavlovic, Z., Perkin, J., Picchi, P., Pietropaolo, F., Plonski, P., Pordes, S., Potenza, R., Pulliam, G., Qian, X., Qiuguang, L., Raaf, J.L., Radeka, V., Rameika, R., Rappoldi, A., Raselli, G.L., Ratoff, P.N., Rebel, B., Richardson, M., Rochester, L., Rossella, M., Rubbia, C., von Rohr, C. Rudolf, Russell, B., Sala, P., Scaramelli, A., Schmitz, D.W., Schukraft, A., Seligman, W., Shaevitz, M.H., Sippach, B., Snider, E., Sobczyk, J., Soderberg, M., Soldner-Rembold, S., Spanu, M., Spitz, J., Spooner, N., Stefan, D., St. John, J., Strauss, T., Sulej, R., Sutera, C.M., Szelc, A.M., Tagg, N., Taylor, C.E., Terao, K., Thiesse, M., Thompson, L., Thomson, M., Thorn, C., Torti, M., Tortorici, F., Toups, M., Touramanis, C., Tsai, Y., Usher, T., Van de Water, R.G., Varanini, F., Ventura, S., Vignoli, C., Wachala, T., Weber, M., Whittington, D., Wilson, P., Wolbers, S., Wongjirad, T., Woodruff, K., Xu, M., Yang, T., Yu, B., Zani, A., Zeller, G.P., Zennamo, J., Zhang, C.Enlace del recurso
Publicado 2015