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1269981por How, Joan, Gallagher, Kathleen M.E., Liu, Yiwen, DeMato, Ashley, Katsis, Katelin, Larson, Rebecca, Leick, Mark B., Neuberg, Donna S., Maus, Marcela V., Hobbs, Gabriela“…Given its size, the spike protein was split into two pools (Spike A or B). IFNγ-producing T-cells were quantified by counting the median spot forming units (SFU) per 2.5x10 (5) PBMCs from duplicate wells. …”
Publicado 2021
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1269982por Nimitha, K J, Singh, Bhupendra, Srivastava, R N, gangwar, Radhe Shyam, Kumar, Rakesh“…This fact can be a complicating factor in the process of treatment adherence and may still increase the perception of pain. The depressive disorder, when associated with physical illness, can cause the emergence of anxiety symptoms. …”
Publicado 2022
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1269983por Johnson, Emma, Campbell, Michael, Reddy, Manoj, Paul, Ryan, Erickson, Brandon, Tjoumakaris, Fotios, Freedman, Kevin, Bishop, Meghan“…The distribution of data was assessed with the Shapiro-Wilk test. Continuous data were assessed with the Student’s t test and Mann-Whitney U tests as appropriate. …”
Publicado 2023
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1269984por Wang, Xiyao, Shi, Wenqiang, Zhao, Shaotong, Gong, Deshun, Li, Shuo, Hu, Cuiping, Chen, Zi-Jiang, Li, Yan, Yan, Junhao“…Different stage C57BL/6J wild-type mouse embryos were collected for immunofluorescence. …”
Publicado 2023
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1269985por Shi, Baolu, Shah, Wasim, Liu, Li, Gong, Chenjia, Zhou, Jianteng, Abbas, Tanveer, Ma, Hui, Zhang, Huan, Yang, Menglei, Zhang, Yuanwei, Ullah, Nadeem, Mahammad, Zubair, Khan, Mazhar, Murtaza, Ghulam, Ali, Asim, Khan, Ranjha, Sha, Jiahao, Yuan, Yan, Shi, Qinghua“…Round spermatids from the littermates of wild-type (WT) and Adad2(Mut/Mut) mice were randomly selected and injected into stimulated WT oocytes. …”
Publicado 2023
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1269986por Magalhães, Henrique Inhauser Riceti, Machado, Felipe Alexandre, Souza, Roberta Figueiroa, Caetano, Marcos Antônio Ferreira, Figliuolo, Vanessa Ribeiro, Coutinho-Silva, Robson, Castelucci, Patricia“…We analyzed the number of calretinin-ir and P2X7 receptor-ir neurons per ganglion, the neuronal profile area (µm²), and corrected total cell fluorescence (CTCF). RESULTS: Cells double labeled for calretinin and P2X7 receptor, cleaved caspase-3, total caspase-3, phospho-NF-κB, or total NF-κB were observed in the WT colitis 24 h and 4 d groups. …”
Publicado 2023
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1269987por Yang, Yi, Nan, Yi, Du, Yu-Hua, Huang, Shi-Cong, Lu, Dou-Dou, Zhang, Jun-Fei, Li, Xia, Chen, Yan, Zhang, Lei, Yuan, Ling“…AIM: To investigate the mechanism of 18β-GRA in inhibiting cell proliferation and promoting autophagy flux in GC cells. …”
Publicado 2023
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1269988por Nelson, Gregory, Fike, John, Limoli, Charles, Obenaus, André, Raber, Jacob, Soltesz, Ivan, Vlkolinský, Roman“…High LET radiation affects all lineages of neural precursor cells and elicits a U-shaped dose–response for cells exhibiting the astrocyte marker GFAP. …”
Publicado 2014
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1269989por Fernández-Triana, Jose L., Whitfield, James B., Rodriguez, Josephine J., Smith, M. Alex, Janzen, Daniel H., Hallwachs, Winnie D., Hajibabaei, Mehrdad, Burns, John M., Solis, M. Alma, Brown, John, Cardinal, Sophie, Goulet, Henri, Hebert, Paul D. N.“…More than half a million specimens of wild-caught Lepidoptera caterpillars have been reared for their parasitoids, identified, and DNA barcoded over a period of 34 years (and ongoing) from Area de Conservación de Guanacaste (ACG), northwestern Costa Rica. …”
Publicado 2014
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1269990“…Unless otherwise noted, all abstracts presented at ENDO are embargoed until the date and time of presentation. …”
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1269991“…Abbreviations: AIEC: adherent-invasive Escherichia coli; AMPK: AMP-activated protein kinase; ATF6: activating transcription factor 6; ATG: autophagy related; Atg16l1[ΔIEC] mice: mice with Atg16l1 depletion specifically in intestinal epithelial cells; Atg16l1[HM] mice: mice hypomorphic for Atg16l1 expression; BCL2: B cell leukemia/lymphoma 2; BECN1: beclin 1, autophagy related; CALCOCO2: calcium binding and coiled-coil domain 2; CASP: caspase; CD: Crohn disease; CGAS: cyclic GMP-AMP synthase; CHUK/IKKA: conserved helix-loop-helix ubiquitous kinase; CLDN2: claudin 2; DAPK1: death associated protein kinase 1; DCs: dendritic cells; DSS: dextran sulfate sodium; EIF2A: eukaryotic translation initiation factor 2A; EIF2AK: eukaryotic translation initiation factor 2 alpha kinase; ER: endoplasmic reticulum; ERBIN: Erbb2 interacting protein; ERN1/IRE1A: ER to nucleus signaling 1; FNBP1L: formin binding protein 1-like; FOXP3: forkhead box P3; GPR65: G-protein coupled receptor 65; GSK3B: glycogen synthase kinase 3 beta; IBD: inflammatory bowel disease; IECs: intestinal epithelial cells; IFN: interferon; IL: interleukin; IL10R: interleukin 10 receptor; IRGM: immunity related GTPase M; ISC: intestinal stem cell; LAMP1: lysosomal-associated membrane protein 1; LAP: LC3-associated phagocytosis; MAP1LC3B: microtubule-associated protein 1 light chain 3 beta; LPS: lipopolysaccharide; LRRK2: leucine-rich repeat kinase 2; MAPK: mitogen-activated protein kinase; MHC: major histocompatibility complex; MIF: macrophage migration inhibitory factor; MIR/miRNA: microRNA; MTMR3: myotubularin related protein 3; MTOR: mechanistic target of rapamycin kinase; MYD88: myeloid differentiation primary response gene 88; NLRP3: NLR family, pyrin domain containing 3; NOD2: nucleotide-binding oligomerization domain containing 2; NPC: Niemann-Pick disease type C; NPC1: NPC intracellular cholesterol transporter 1; OMVs: outer membrane vesicles; OPTN: optineurin; PI3K: phosphoinositide 3-kinase; PRR: pattern-recognition receptor; PTPN2: protein tyrosine phosphatase, non-receptor type 2; PTPN22: protein tyrosine phosphatase, non-receptor type 22 (lymphoid); PYCARD/ASC: PYD and CARD domain containing; RAB2A: RAB2A, member RAS oncogene family; RELA: v-rel reticuloendotheliosis viral oncogene homolog A (avian); RIPK2: receptor (TNFRSF)-interacting serine-threonine kinase 2; ROS: reactive oxygen species; SNPs: single nucleotide polymorphisms; SQSTM1: sequestosome 1; TAX1BP1: Tax1 binding protein 1; Th: T helper 1; TIRAP/TRIF: toll-interleukin 1 receptor (TIR) domain-containing adaptor protein; TLR: toll-like receptor; TMEM173/STING: transmembrane protein 173; TMEM59: transmembrane protein 59; TNF/TNFA: tumor necrosis factor; Treg: regulatory T; TREM1: triggering receptor expressed on myeloid cells 1; UC: ulcerative colitis; ULK1: unc-51 like autophagy activating kinase 1; WT: wild-type; XBP1: X-box binding protein 1; XIAP: X-linked inhibitor of apoptosis.…”
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1269992por Bridgewater, John A, Pugh, Siân A, Maishman, Tom, Eminton, Zina, Mellor, Jane, Whitehead, Amy, Stanton, Louise, Radford, Michael, Corkhill, Andrea, Griffiths, Gareth O, Falk, Stephen, Valle, Juan W, O'Reilly, Derek, Siriwardena, Ajith K, Hornbuckle, Joanne, Rees, Myrddin, Iveson, Timothy J, Hickish, Tamas, Garden, O James, Cunningham, David, Maughan, Timothy S, Primrose, John N“…Safety analyses included all randomly assigned patients. This trial is registered with ISRCTN, number 22944367. …”
Publicado 2020
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1269993por Souza, William M, Amorim, Mariene R, Sesti-Costa, Renata, Coimbra, Lais D, Brunetti, Natalia S, Toledo-Teixeira, Daniel A, de Souza, Gabriela F, Muraro, Stefanie P, Parise, Pierina L, Barbosa, Priscilla P, Bispo-dos-Santos, Karina, Mofatto, Luciana S, Simeoni, Camila L, Claro, Ingra M, Duarte, Adriana S S, Coletti, Thais M, Zangirolami, Audrey B, Costa-Lima, Carolina, Gomes, Arilson B S P, Buscaratti, Lucas I, Sales, Flavia C, Costa, Vitor A, Franco, Lucas A M, Candido, Darlan S, Pybus, Oliver G, de Jesus, Jaqueline G, Silva, Camila A M, Ramundo, Mariana S, Ferreira, Giulia M, Pinho, Mariana C, Souza, Leandro M, Rocha, Esmenia C, Andrade, Pamela S, Crispim, Myuki A E, Maktura, Grazielle C, Manuli, Erika R, Santos, Magnun N N, Camilo, Cecilia C, Angerami, Rodrigo N, Moretti, Maria L, Spilki, Fernando R, Arns, Clarice W, Addas-Carvalho, Marcelo, Benites, Bruno D, Vinolo, Marco A R, Mori, Marcelo A S, Gaburo, Nelson, Dye, Christopher, Marques-Souza, Henrique, Marques, Rafael E, Farias, Alessandro S, Diamond, Michael S, Faria, Nuno R, Sabino, Ester C, Granja, Fabiana, Proença-Módena, Jose Luiz“…We aimed to investigate whether isolates of wild-type P.1 lineage SARS-CoV-2 can escape from neutralising antibodies generated by a polyclonal immune response. …”
Publicado 2021
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1269994por Schultheis, Katherine, Reed, Charles C, Andrade, Viviane M, Kalia, Richa, Tur, Jared, Schouest, Blake, Elwood, Dustin, Maricic, Igor, Doan, Arthur, Eblimit, Zeena, Pezzoli, Patrick, Amante, Dinah, yang, maria, Fader, Joseph g, Ferrer, Roi, Weiner, David, Kim, J Joseph, Humeau, Laurent, Ramos, Stephanie, Smith, Trevor R F, Broderick, Kate“…INO-4802 also neutralized P.1 (1026.6) (Figure 2). pWT, pB.1.351 or INO-4802 induced similar T-cell responses against all variants. INO-4802 skewed towards a TH1-response. …”
Publicado 2021
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1269995“…Blood counts demonstrated a hemoglobin count of 79 g/L, white blood cell count of 0.7×10 (9), platelet count of 58×10 (9)/L, and neutrophil count of 0.2×10 (9)/L. …”
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1269996por Mettu, Niharika B., Ou, Fang-Shu, Zemla, Tyler J., Halfdanarson, Thorvardur R., Lenz, Heinz-Josef, Breakstone, Rimini A., Boland, Patrick M., Crysler, Oxana V., Wu, Christina, Nixon, Andrew B., Bolch, Emily, Niedzwiecki, Donna, Elsing, Alicia, Hurwitz, Herbert I., Fakih, Marwan G., Bekaii-Saab, Tanios“…Adult patients with mCRC who experienced disease progression while receiving fluoropyrimidine, oxaliplatin, irinotecan, bevacizumab, and anti–epidermal growth factor receptor antibody therapy (if the patient had a RAS wild-type tumor) were included. …”
Publicado 2022
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1269997por Jin, Pengfei, Guo, Xiling, Chen, Wei, Ma, Shihua, Pan, Hongxing, Dai, Lianpan, Du, Pan, Wang, Lili, Jin, Lairun, Chen, Yin, Shi, Fengjuan, Liu, Jingxian, Xu, Xiaoyu, Zhang, Yanan, Gao, George F., Chen, Cancan, Feng, Jialu, Li, Jingxin, Zhu, Fengcai“…A total of 26 participants (21.7%) reported solicited adverse reactions within 7 days post boost vaccinations, and all the reported adverse reactions were mild, with 13 (32.5%) in CV/ZF/ZF (D0-D28-M5) regimen, 7 (35.0%) in CV/ZF (D0- M5) regimen, 4 (10.0%) in CV/ZF/ZF (D0-D56-M6) regimen, and 2 (10.0%) in CV/ZF (D0-M6) regimen, respectively. …”
Publicado 2022
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1269998por Romeo, Margarita, Gil-Martín, Marta, Gaba, Lydia, Teruel, Iris, Taus, Álvaro, Fina, Claudia, Masvidal, Maria, Murata, Paola, Fernández-Plana, Julen, Martínez, Alejandro, Pérez, Cristina, García, Yolanda, Rodriguez, Valerie, Cros, Sara, Parera, Marta, Zanui, Montserrat, Catot, Silvia, Pardo, Beatriz, Plaja, Andrea, Esteve, Anna, Barretina-Ginesta, Maria Pilar“…However, within this group, analysis according to BRCA status showed that BRCA mutant patients (n = 35) presented higher rates of progression and worse survival outcomes under subsequent platinum than BRCA wild type patients (n = 39), with statistically significant differences. …”
Publicado 2022
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1269999por Assoune, Gaelle“… </span><br><span style="color:hsl(30,75%,60%);">How to allow them to blossom and develop what we call psycho-social skills? </span><br><span style="color:hsl(30,75%,60%);">How to understand them in order to reduce their stress and promote their learning?…”
Publicado 2023
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1270000por Achard, P., Adriani, O., Aguilar-Benitez, M., Alcaraz, J., Alemanni, G., Allaby, J., Aloisio, A., Alviggi, M.G., Anderhub, H., Andreev, Valery P., Anselmo, F., Arefev, A., Azemoon, T., Aziz, T., Bagnaia, P., Bajo, A., Baksay, G., Baksay, L., Baldew, S.V., Banerjee, S., Barczyk, A., Barillere, R., Bartalini, P., Basile, M., Batalova, N., Battiston, R., Bay, A., Becattini, F., Becker, U., Behner, F., Bellucci, L., Berbeco, R., Berdugo, J., Berges, P., Bertucci, B., Betev, B.L., Biasini, M., Biglietti, M., Biland, A., Blaising, J.J., Blyth, S.C., Bobbink, G.J., Bohm, A., Boldizsar, L., Borgia, B., Bottai, S., Bourilkov, D., Bourquin, M., Braccini, S., Branson, J.G., Brochu, F., Burger, J.D., Burger, W.J., Cai, X.D., Capell, M., Cara Romeo, G., Carlino, G., Cartacci, A., Casaus, J., Cavallari, F., Cavallo, N., Cecchi, C., Cerrada, M., Chamizo, M., Chang, Y.H., Chemarin, M., Chen, A., Chen, G., Chen, G.M., Chen, H.F., Chen, H.S., Chiefari, G., Cifarelli, L., Cindolo, F., Clare, I., Clare, R., Coignet, G., Colino, N., Costantini, S., de la Cruz, B., Cucciarelli, S., van Dalen, J.A., de Asmundis, R., Deglon, P., Debreczeni, J., Degre, A., Dehmelt, K., Deiters, K., della Volpe, D., Delmeire, E., Denes, P., DeNotaristefani, F., De Salvo, A., Diemoz, M., Dierckxsens, M., Dionisi, C., Dittmar, M., Doria, A., Dova, M.T., Duchesneau, D., Duda, M., Echenard, B., Eline, A., El Hage, A., El Mamouni, H., Engler, A., Eppling, F.J., Extermann, P., Falagan, M.A., Falciano, S., Favara, A., Fay, J., Fedin, O., Felcini, M., Ferguson, T., Fesefeldt, H., Fiandrini, E., Field, J.H., Filthaut, F., Fisher, P.H., Fisher, W., Fisk, I., Forconi, G., Freudenreich, K., Furetta, C., Galaktionov, Iouri, Ganguli, S.N., Garcia-Abia, Pablo, Gataullin, M., Gentile, S., Giagu, S., Gong, Z.F., Grenier, Gerald Jean, Grimm, O., Gruenewald, M.W., Guida, M., van Gulik, R., Gupta, V.K., Gurtu, A., Gutay, L.J., Haas, D., Hatzifotiadou, D., Hebbeker, T., Herve, Alain, Hirschfelder, J., Hofer, H., Hohlmann, M., Holzner, G., Hou, S.R., Hu, Y., Jin, B.N., Jones, Lawrence W., de Jong, P., Josa-Mutuberria, I., Kafer, D., Kaur, M., Kienzle-Focacci, M.N., Kim, J.K., Kirkby, Jasper, Kittel, W., Klimentov, A., Konig, A.C., Kopal, M., Koutsenko, V., Kraber, M., Kraemer, R.W., Kruger, A., Kunin, A., Ladron de Guevara, P., Laktineh, I., Landi, G., Lebeau, M., Lebedev, A., Lebrun, P., Lecomte, P., Lecoq, P., Le Coultre, P., Le Goff, J.M., Leiste, R., Levtchenko, M., Levtchenko, P., Li, C., Likhoded, S., Lin, C.H., Lin, W.T., Linde, F.L., Lista, L., Liu, Z.A., Lohmann, W., Longo, E., Lu, Y.S., Luci, C., Luminari, L., Lustermann, W., Ma, W.G., Malgeri, L., Malinin, A., Mana, C., Mans, J., Martin, J.P., Marzano, F., Mazumdar, K., McNeil, R.R., Mele, S., Merola, L., Meschini, M., Metzger, W.J., Mihul, A., Milcent, H., Mirabelli, G., Mnich, J., Mohanty, G.B., Muanza, G.S., Muijs, A.J.M., Musicar, B., Musy, M., Nagy, S., Natale, S., Napolitano, M., Nessi-Tedaldi, F., Newman, H., Nisati, A., Novak, T., Kluge, Hannelies, Ofierzynski, R., Organtini, G., Pal, I., Palomares, C., Paolucci, P., Paramatti, R., Passaleva, G., Patricelli, S., Paul, Thomas Cantzon, Pauluzzi, M., Paus, C., Pauss, F., Pedace, M., Pensotti, S., Perret-Gallix, D., Petersen, B., Piccolo, D., Pierella, F., Pioppi, M., Piroue, P.A., Pistolesi, E., Plyaskin, V., Pohl, M., Pojidaev, V., Pothier, J., Prokofev, D., Quartieri, J., Rahal-Callot, G., Rahaman, Mohammad Azizur, Raics, P., Raja, N., Ramelli, R., Rancoita, P.G., Ranieri, R., Raspereza, A., Razis, P., Ren, D., Rescigno, M., Reucroft, S., Riemann, S., Riles, Keith, Roe, B.P., Romero, L., Rosca, A., Rosier-Lees, S., Roth, Stefan, Rosenbleck, C., Roux, B., Rubio, J.A., Ruggiero, G., Rykaczewski, H., Sakharov, A., Saremi, S., Sarkar, S., Salicio, J., Sanchez, E., Schafer, C., Schegelsky, V., Schopper, H., Schotanus, D.J., Sciacca, C., Servoli, L., Shevchenko, S., Shivarov, N., Shoutko, V., Shumilov, E., Shvorob, A., Son, D., Souga, C., Spillantini, P., Steuer, M., Stickland, D.P., Stoyanov, B., Straessner, A., Sudhakar, K., Sultanov, G., Sun, L.Z., Sushkov, S., Suter, H., Swain, J.D., Szillasi, Z., Tang, X.W., Tarjan, P., Tauscher, L., Taylor, L., Tellili, B., Teyssier, D., Timmermans, Charles, Ting, Samuel C.C., Ting, S.M., Tonwar, S.C., Toth, J., Tully, C., Tung, K.L., Ulbricht, J., Valente, E., Van de Walle, R.T., Vasquez, R., Veszpremi, V., Vesztergombi, G., Vetlitsky, I., Vicinanza, D., Viertel, G., Villa, S., Vivargent, M., Vlachos, S., Vodopianov, I., Vogel, H., Vogt, H., Vorobev, I., Vorobyov, A.A., Wadhwa, M., Wang, Q., Wang, X.L., Wang, Z.M., Weber, M., Wienemann, P., Wilkens, H., Wynhoff, S., Xia, L., Xu, Z.Z., Yamamoto, J., Yang, B.Z., Yang, C.G., Yang, H.J., Yang, M., Yeh, S.C., Zalite, A., Zalite, Yu., Zhang, Z.P., Zhao, J., Zhu, G.Y., Zhu, R.Y., Zhuang, H.L., Zichichi, A., Zimmermann, B., Zoller, M.Enlace del recurso
Publicado 2003
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