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1081por Ginestal, Ricardo, Rubio-Terrés, Carlos, Morán, Olga Durán, Rubio-Rodríguez, Darío, Los Santos, Heidi De, Ordoñez, Cristina, Sánchez-Magro, Isabel“…AIM: To analyze the cost–effectiveness of treatment of relapsing remitting multiple sclerosis (RRMS) with cladribine tablets (CladT) and dimethyl fumarate (DMF) from the perspective of the Spanish National Health System (NHS). …”
Publicado 2023
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1082“…However, the use of disease-modifying therapies has profoundly contributed to the improvement in the morbidity of the disorder. Diroximel fumarate (DRF) is a second-generation drug that has seen success in the treatment of relapsing-remitting MS (RRMS). …”
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1083“…[Image: see text] Crystallization has revolutionized the field of solid-state formulations by modulating the physiochemical and release profile of active pharmaceutical ingredients (APIs). Dimethyl fumarate (DF), an FDA-approved first-line drug for relapsing–remitting multiple sclerosis, has a sublimation problem, leading to loss of the drug during its processing. …”
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1084por Abolfazli, Roya, Sahraian, Mohammad Ali, Tayebi, Atefeh, Kafi, Hamidreza, Samadzadeh, Sara“…Background: This study evaluates the real-world safety and discontinuation rate of Zadiva(®) (generic product of dimethyl fumarate (DMF)) in Iranian patients with relapsing–remitting multiple sclerosis (RRMS), supplementing existing clinical evidence from randomized controlled trials. …”
Publicado 2023
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1085por Lei, Jie, Pan, Yujia, Gao, Rui, He, Bin, Wang, Zifeng, Lei, Xinxing, Zhang, Zijian, Yang, Na, Yan, Min“…Finally, we identified fumarate hydratase (FH) as the direct interacting target of rutaecarpine. …”
Publicado 2023
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1086por Woldemedihn, Gezahegn M, Aberra, Hanna, Desalegn, Hailemichael, Berhe, Nega, Belay, Denekew Bitew, Rueegg, Corina S, Johannessen, Asgeir“…BACKGROUND: Data on renal safety of tenofovir disoproxil fumarate (TDF) treatment among individuals with chronic hepatitis B (CHB) are inconsistent. …”
Publicado 2023
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1087“…OBJECTIVE: To examine the risk of incident hypertension and statin initiation among adult (age ≥18 years) health plan members starting PrEP with tenofovir alafenamide fumarate (TAF) compared with propensity score–matched adults taking tenofovir disoproxil fumarate (TDF). …”
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1088por Wollheim, Frank A“…The 2nd Annual European League Against Rheumatism (EULAR) Congress, held in Prague, 13–16 June 2001, was an impressive event with a record turnout of 8300 delegates. …”
Publicado 2001
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1089por Wollheim, Frank A“…The 3(rd) Annual EULAR Congress, held in Stockholm on 12–15 June 2002, had a turnout of 8300 delegates, almost identical to last year's record attendance level in Prague. …”
Publicado 2002
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1090por Ellrichmann, Gisa, Petrasch-Parwez, Elisabeth, Lee, De-Hyung, Reick, Christiane, Arning, Larissa, Saft, Carsten, Gold, Ralf, Linker, Ralf A.“…Some lines of evidence speak for the contribution of oxidative stress to neuronal tissue damage. The fumaric acid ester dimethylfumarate (DMF) is a new disease modifying therapy currently in phase III studies for relapsing-remitting multiple sclerosis. …”
Publicado 2011
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1091por Maiti, Rituparna, Jaida, Jyothirmai, Rahman, Jalelur, Gaddam, Rajasri, Palani, AnuradhaEnlace del recurso
Publicado 2011
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1092por Pontrelli, Giuseppe, Cotugno, Nicola, Amodio, Donato, Zangari, Paola, Tchidjou, Hyppolite K, Baldassari, Stefania, Palma, Paolo, Bernardi, Stefania“…Our aim is to assess renal function in HIV infected paediatric patients, who may be particularly affected and are likely to take ART for longer than adults, and investigate the long term role of Tenofovir Disoproxil Fumarate (TDF) alone or co-administered with Ritonavir-boosted Protease Inhibitors (PI). …”
Publicado 2012
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1093“…CONCLUSIONS: ACR/EULAR definitions of remission developed for trials are similarly valid in observational studies in RA and could be used in practice.…”
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1094por Kennish, Lauren, Labitigan, Monalyn, Budoff, Sam, Filopoulos, Maria T, McCracken, W Andrew, Swearingen, Christopher J, Yazici, Yusuf“…INTERVENTIONS: The ACR/EULAR RA criteria were applied, with questions followed by a targeted musculoskeletal exam. …”
Publicado 2012
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1095por Kim, Ji Young, Cho, Soo-Kyung, Han, Minkyung, Choi, Yun Young, Bae, Sang-Cheol, Sung, Yoon-Kyoung“…We aimed to investigate the role of bone scintigraphy (BS) in the diagnosis of rheumatoid arthritis (RA) as a supplement to the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) criteria. A total of 156 patients who underwent BS with screening laboratory to confirm RA were enrolled. …”
Publicado 2014
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1096“…Tenofovir disoproxil fumarate (TDF) has demonstrated potent antiviral activity in clinical trials, but data in Asian-Americans from community studies are lacking. …”
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1097“…Herein, we review the pharmacology and efficacy of dimethyl fumarate (BG-12) to date and its role in the evolving marketplace.…”
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1099por Hsieh, Ju-Yi, Liu, Jyung-Hurng, Yang, Pai-Chun, Lin, Chi-Li, Liu, Guang-Yaw, Hung, Hui-Chih“…Among these analogs, mesaconate, trans-aconitate, monomethyl fumarate and monoethyl fumarate were allosteric activators of the enzyme, while oxaloacetate, diethyl oxalacetate, and dimethyl fumarate were found to be allosteric inhibitors of human m-NAD(P)-ME. …”
Publicado 2014
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1100por Jose, Sophie, Hamzah, Lisa, Campbell, Lucy J., Hill, Teresa, Fisher, Martin, Leen, Clifford, Gilson, Richard, Walsh, John, Nelson, Mark, Hay, Phillip, Johnson, Margaret, Chadwick, David, Nitsch, Dorothea, Jones, Rachael, Sabin, Caroline A., Post, Frank A., Ainsworth, Jonathan, Anderson, Jane, Babiker, Abdel, Chadwick, David, Delpech, Valerie, Dunn, David, Fisher, Martin, Gazzard, Brian, Gilson, Richard, Gompels, Mark, Hay, Phillip, Hill, Teresa, Johnson, Margaret, Kegg, Stephen, Leen, Clifford, Nelson, Mark, Orkin, Chloe, Palfreeman, Adrian, Phillips, Andrew, Pillay, Deenan, Post, Frank, Sabin, Caroline, Sachikonye, Memory, Schwenk, Achim, Walsh, John, Hill, Teresa, Huntington, Susie, Josie, Sophie, Phillips, Andrew, Sabin, Caroline, Thornton, Alicia, Dunn, David, Glabay, Adam, Orkin, C., Garrett, N., Lynch, J., Hand, J., de Souza, C., Fisher, M., Perry, N., Tilbury, S., Churchill, D., Gazzard, B., Nelson, M., Waxman, M., Asboe, D., Mandalia, S., Delpech, V., Anderson, J., Munshi, S., Korat, H., Poulton, M., Taylor, C., Gleisner, Z., Campbell, L., Babiker, Abdel, Dunn, David, Glabay, Adam, Gilson, R., Brima, N., Williams, I., Schwenk, A., Ainsworth, J., Wood, C., Miller, S., Johnson, M., Youle, M., Lampe, F., Smith, C., Grabowska, H., Chaloner, C., Puradiredja, D., Walsh, J., Weber, J., Ramzan, F., Mackie, N., Winston, A., Leen, C., Wilson, A., Gompels, M., Allan, S., Palfreeman, A., Moore, A., Chadwick, D., Wakeman, K., Kegg, Stephen, Main, Paul, Mitchell, Hunter, Sachikonye, Memory, Hay, Phillip, Dhillon, Mandip“…Tenofovir disoproxil fumarate (TDF) has been linked to renal impairment, but the extent to which this impairment is reversible is unclear. …”
Publicado 2014
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