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  1. 1121
    “…Moreover, fumarate replenishment to the sdhA mutant significantly increased its virulence toward C. elegans. …”
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    A multi-omic analysis reveals the role of fumarate in regulating the virulence of enterohemorrhagic Escherichia coli
  2. 1122
    “…The integrated ACR/EULAR and US scoring system can improve the diagnosis of patients with clinical SS.…”
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    Combined classification system based on ACR/EULAR and ultrasonographic scores for improving the diagnosis of Sjögren's syndrome
  3. 1123
    “…The ability of Rhizopus oryzae to produce fumaric acid in the presence of glycerol and/or various monosaccharides as carbon sources was examined for seventeen different strains of this fungi. …”
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    A co-utilization strategy to consume glycerol and monosaccharides by Rhizopus strains for fumaric acid production
  4. 1124
    “…We previously described the novel synthesis of a copper high-aspect ratio structure (CuHARS) biohybrid material using cystine. While extremely stable in water, CuHARS is completely (but slowly) degradable in cellular media. …”
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    Integration of a Copper-Containing Biohybrid (CuHARS) with Cellulose for Subsequent Degradation and Biomedical Control
  5. 1125
    por Ojha, Smriti, Kumar, Babita
    Publicado 2018
    “…Purpose: The objective of this study was to synthesize and statistically optimize dimethyl fumarate (DMF) loaded solid lipid nanoparticles (SLNs) for better management of multiple sclerosis (MS). …”
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    Preparation and Statistical Modeling of Solid Lipid Nanoparticles of Dimethyl Fumarate for Better Management of Multiple Sclerosis
  6. 1126
    “…The current study aimed to rationally develop and characterize pH-sensitive controlled release hydrogels by graft polymerization of gelatin (Gel) and hydroxypropyl methyl cellulose (HPMC) in the presence of glutaraldehyde (GA) using quetiapine fumarate for the treatment of schizophrenia. The prepared hydrogels discs were subjected to various physicochemical studies including: swelling, diffusion, porosity, sol-gel analysis, Fourier transform infrared spectroscopy, differential scanning calorimetry, and scanning electron microscopy. …”
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    Pharmacokinetic evaluation of quetiapine fumarate controlled release hybrid hydrogel: a healthier treatment of schizophrenia
  7. 1127
    “…We identified that C93 of GPX4 is readily post‐translationally modified by fumarates that accumulate in conditions of FH (−/−), and that C93 modification represses GPX4 activity. …”
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    Fumarate hydratase inactivation in hereditary leiomyomatosis and renal cell cancer is synthetic lethal with ferroptosis induction
  8. 1128
    “…An altered response to DNA damage is commonly associated with genomic instability, a hallmark of cancer. Fumarate hydratase (FH) was recently characterised as a DNA repair factor required in non-homologous end-joining (NHEJ) through the local production of fumarate. …”
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    Fumarate hydratase loss promotes mitotic entry in the presence of DNA damage after ionising radiation
  9. 1129
    “…The membrane-embedded quinol:fumarate reductase (QFR) in anaerobic bacteria catalyzes the reduction of fumarate to succinate by quinol in the anaerobic respiratory chain. …”
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    Structural insights into the electron/proton transfer pathways in the quinol:fumarate reductase from Desulfovibrio gigas
  10. 1130
    “…OBJECTIVE: To elucidate the immunomodulatory effects of dimethyl fumarate (DMF) on B cells in patients with relapsing MS receiving DMF as a “1st-line” vs “2nd-line” therapy. …”
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    Dimethyl fumarate as a first- vs second-line therapy in MS: Focus on B cells
  11. 1131
    “…METHODS: We studied subjects who, after a median of 4.2 years of ART, replaced zidovudine or stavudine with tenofovir disoproxil fumarate while continuing lamivudine and an NNRTI. …”
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    Drug resistance outcomes of long-term ART with tenofovir disoproxil fumarate in the absence of virological monitoring
  12. 1132
    “…BACKGROUND: Formoterol fumarate inhalation solution (FFIS; Perforomist(®)) is a long-acting β(2)-agonist (LABA) marketed in the US as a nebulized COPD maintenance treatment. …”
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    Long-term safety and efficacy of formoterol fumarate inhalation solution in patients with moderate-to-severe COPD
  13. 1133
    “…Abnormalities in tricarboxylic acid (TCA) cycle function were related to a variety of pathological processes. Fumarate hydratase (FH) is a required enzyme in the TCA cycle. …”
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    Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro
  14. 1134
    “…Here, we present the crystal structure of the mitochondrial isoform of class I fumarate hydratase (FH) from Leishmania major and compare it to the previously determined cytosolic Leishmania major isoform. …”
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    Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate
  15. 1135
    “…Aclidinium bromide/formoterol fumarate (AB/FF) 400/12 µg is a twice-daily long-acting muscarinic receptor antagonist and long-acting β(2) agonist (LAMA/LABA) dual-bronchodilator maintenance therapy used to relieve symptoms and reduce future risk of exacerbations in adults with chronic obstructive pulmonary disease (COPD). …”
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    Aclidinium bromide in fixed-dose combination with formoterol fumarate in the management of COPD: an update on the evidence base
  16. 1136
    “…High throughput screening of clinically used drugs identified Dimethyl fumarate (DMF) as protective in FA patient cells. Here we demonstrate that DMF significantly increases frataxin gene (FXN) expression in FA cell model, FA mouse model and in DMF treated humans. …”
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    Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich’s Ataxia
  17. 1137
    “…Dimethyl fumarate (DMF) is a first-line-treatment for relapsing-remitting multiple sclerosis (RRMS). …”
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    Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes
  18. 1138
    “…Here we aim to evaluate the immunomodulatory effect of dimethyl fumarate (DMF), an FDA approved small molecule drug, in the house dust mite (HDM)‐induced experimental model of allergic asthma. …”
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    Dimethyl fumarate abrogates dust mite‐induced allergic asthma by altering dendritic cell function
  19. 1139
    “…Tenofovir disproxil fumarate (TDF) has been shown to affect neurogenesis in brains of mice and mitochondria in neurons. …”
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    Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice
  20. 1140
    “…Tenofovir disoproxil fumarate (TDF) is thought to cause varying degrees of hypophosphatemia in patients with chronic hepatitis B (CHB). …”
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    Risk factors associated with hypophosphatemia in chronic Hepatitis B patients treated with tenofovir disoproxil fumarate
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