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  1. 1281
    “…BACKGROUND: Succinate dehydrogenase (SDH) and fumarate hydratase (FH) are tricarboxylic acid (TCA) cycle enzymes that are also known to act as tumour suppressor genes. …”
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    No evidence for promoter region methylation of the succinate dehydrogenase and fumarate hydratase tumour suppressor genes in breast cancer
  2. 1282
    por Vora, D. N., Kadav, A. A.
    Publicado 2008
    “…Mean recovery was 99.1% and 98.6% for bisoprolol fumarate and amlodipine besylate, respectively.…”
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    Development and Validation of a Simultaneous HPLC Method for Estimation of Bisoprolol Fumarate and Amlodipine Besylate from Tablets
  3. 1283
    por Pan, Ya-Ru
    Publicado 2007
    “…Weak C—H⋯O inter­actions between uncoordinated carboxyl­ate O atoms of fumaric acid and water mol­ecules contribute to the crystal packing stability.…”
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    catena-Poly[[[tetra­aqua­cadmium(II)]-μ-4,4′-bipyridine] fumarate tetra­hydrate]
  4. 1284
    “…In the title salt, C(16)H(21)N(4) (+)·ClO(4) (−)·0.5C(4)H(4)O(4), fumaric acid mol­ecules, situated across crystallographic inversion centres, are O—H⋯N hydrogen bonded to two protonated 1,4-bis­(4-pyridylmeth­yl)piperazine cations, forming trimolecular units. …”
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    1,4-Bis(4-pyridylmeth­yl)piperazin-1-ium perchlorate fumaric acid hemisolvate
  5. 1285
    por Sharma, R., Mehta, K.
    Publicado 2010
    “…Efavirenz, tenofovir disoproxil fumarate and lamivudine obeyed Beer’s law in the concentration range of 10-60, 5-30 and 5-30 μg/ml, respectively. …”
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    Simultaneous Spectrophotometric Estimation of Tenofovir Disoproxil Fumarate and Lamivudine in Three Component Tablet Formulation Containing Efavirenz
  6. 1286
    “…Thus, novel therapeutics enhancing cellular resistance to free radicals could prove useful for MS treatment. Here, fumaric acid esters (FAE) are a new, orally available treatment option which had already been tested in phase II/III MS trials demonstrating beneficial effects on relapse rates and magnetic resonance imaging markers. …”
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    Online Artículo Texto
    Mechanisms of Oxidative Damage in Multiple Sclerosis and Neurodegenerative Diseases: Therapeutic Modulation via Fumaric Acid Esters
  7. 1287
    “…The optimized bisoprolol fumarate matrix tablets showed prolonged sustained release of bisoprolol fumarate over 6 hours. …”
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    Use of Response Surface Methodology in the Formulation and Optimization of Bisoprolol Fumarate Matrix Tablets for Sustained Drug Release
  8. 1288
    “…Fumaric acid esters (FAE) are oral analogs of fumarate that have recently been shown to decrease relapse rate and disease progression in multiple sclerosis (MS), prompting to investigate their protective potential in other neurological diseases such as amyotrophic lateral sclerosis (ALS). …”
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    Fumaric Acid Esters Stimulate Astrocytic VEGF Expression through HIF-1α and Nrf2
  9. 1289
    “…INTRODUCTION: The objective of the present study was to design ferrous fumarate (FF) sustained release (SR) pellets using of cow ghee (CG) as an important hot-melt coating (HMC) agent. …”
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    Design of sustained release pellets of ferrous fumarate using cow ghee as hot-melt coating agent
  10. 1290
    “…In this article, the 2010 European League against Rheumatism (EULAR) recommendations for the management of rheumatoid arthritis (RA) with synthetic and biological disease-modifying antirheumatic drugs (sDMARDs and bDMARDs, respectively) have been updated. …”
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    EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update
  11. 1291
    “…Tenofovir disoproxil fumarate (TDF) is widely used to treat hepatitis B virus (HBV) patients in the USA and Europe. …”
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    Virologic breakthrough in a patient with chronic hepatitis B by combination treatment with tenofovir disoproxil fumarate and entecavir
  12. 1292
    “…The title compound, poly[di­aqua­tris­(μ(4)-but-2-enedioato)(μ(2)-but-2-enedioic acid)dilanthanum(III)], [La(2)(C(4)H(2)O(4))(3)(C(4)H(4)O(4))(H(2)O)(2)](n), was synthesized by the reaction of lanthanum chloride penta­hydrate with fumaric acid under hydro­thermal conditions. The asymmetric unit comprises an La(III) cation, one and a half fumarate dianions (L (2−)), one a half-mol­ecule of fumaric acid (H(2) L) and one coordinated water mol­ecule. …”
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    Hydro­thermal synthesis and crystal structure of a new lanthanum(III) coordination polymer with fumaric acid
  13. 1293
    “…BACKGROUND: Long-term tenofovir disoproxil fumarate (TDF) treatment for chronic hepatitis B (CHB) is associated with sustained viral suppression and regression of fibrosis and cirrhosis at year 5 (240 weeks) and no TDF resistance through 6 years (288 weeks). …”
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    Seven-Year Efficacy and Safety of Treatment with Tenofovir Disoproxil Fumarate for Chronic Hepatitis B Virus Infection
  14. 1294
    “…BACKGROUND: Fumaric acid esters (FAEs), an oral immunomodulating treatment for psoriasis and multiple sclerosis, have been anecdotally associated with proximal renal tubular dysfunction due to a drug-induced Fanconi syndrome. …”
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    Drug-induced Fanconi syndrome associated with fumaric acid esters treatment for psoriasis: a case series
  15. 1295
    “…BACKGROUND: Delayed-release dimethyl fumarate (DMF), indicated for the treatment of patients with relapsing-remitting multiple sclerosis (MS), is a disease-modifying therapy with potential immunomodulatory and neuroprotective effects. …”
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    Characterizing absolute lymphocyte count profiles in dimethyl fumarate–treated patients with MS: Patient management considerations
  16. 1296
    “…A fixed-dose inhaled corticosteroid/long-acting β(2)-agonist (ICS/LABA) combination of extrafine beclometasone dipropionate and formoterol fumarate (BDP/FF) has been recently approved for use in chronic obstructive pulmonary disease (COPD). …”
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    Extrafine beclometasone diproprionate/formoterol fumarate: a review of its effects in chronic obstructive pulmonary disease
  17. 1297
    “…Sanitizing effectiveness of slightly acidic electrolyzed water (SAEW) and fumaric acid (FA) at different dipping temperatures (25–60 °C), times (1–5 min), and concentrations (5–30 ppm for SAEW and 0.125%–0.5% for FA) on pure cultures of two Gram positive pathogens Staphylococcus aureus (SA) and Listeria monocytogenes (LM) and two Gram negative pathogens Escherichia coli O157:H7 (EC) and Salmonella Typhimurium (ST) was evaluated. …”
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    Fumaric Acid and Slightly Acidic Electrolyzed Water Inactivate Gram Positive and Gram Negative Foodborne Pathogens
  18. 1298
    “…BACKGROUND: Dimethyl fumarate (DMF), working via its metabolite monomethylfumarate (MMF), acts as a potent antioxidant and immunomodulator in animal models of neurologic disease and in patients with multiple sclerosis. …”
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    Fumarate modulates the immune/inflammatory response and rescues nerve cells and neurological function after stroke in rats
  19. 1299
    “…Dimethyl fumarate (DMF) is indicated for the treatment of relapsing multiple sclerosis and may exert therapeutic effects via activation of the nuclear factor (erythroid-derived 2)-like 2 (NRF2) pathway. …”
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    The NRF2 transcriptional target, OSGIN1, contributes to monomethyl fumarate-mediated cytoprotection in human astrocytes
  20. 1300
    “…Here we investigated whether the disease-modifying therapy of relapsing-remitting MS (RRMS) with dimethyl fumarate (DMF) influences the sensitivity of T cells in the peripheral blood of patients towards Treg-mediated suppression. …”
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    Dimethyl Fumarate Therapy Significantly Improves the Responsiveness of T Cells in Multiple Sclerosis Patients for Immunoregulation by Regulatory T Cells
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