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  1. 1
    “…We developed a live attenuated L. mexicana Cen(−/−)(LmexCen(−/−)) strain as a vaccine candidate that showed excellent efficacy, characterized by reduced Th2 and enhanced Th1 responses in C57BL/6 and BALB/c mice, respectively, compared to wild-type L. mexicana (LmexWT) infection. …”
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    Leishmania mexicana centrin knockout parasites promote M1-polarizing metabolic changes
  2. 2
    “…Immunization with LmexCen(−/−) is also efficacious against challenge with WT L. mexicana parasites in genetically different BALB/c and C57BL/6 mouse models. …”
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    Centrin-deficient Leishmania mexicana confers protection against New World cutaneous leishmaniasis
  3. 3
    “…While C57BL/6 mice infected in the ear with L. major mount a vigorous Th1 response and resolve their lesions, the Th1 response in C57BL/6 mice infected with L. mexicana is more limited, resulting in chronic, non-healing lesions. …”
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    Leishmania mexicana Induces Limited Recruitment and Activation of Monocytes and Monocyte-Derived Dendritic Cells Early during Infection
  4. 4
    “…Using flow cytometry, we identified Tex cells subtypes based on PD-1, CXCR5 and TIM-3 expressions in draining lymph nodes (dLNs) and lesion sites of C57BL/6 mice infected with L. mexicana at 30-, 60- and 90-days post-infection. …”
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    CXCR5 and TIM-3 expressions define distinct exhausted T cell subsets in experimental cutaneous infection with Leishmania mexicana
  5. 5
    por Buxbaum, Laurence U.
    Publicado 2013
    “…Infection with the intracellular protozoan parasite Leishmania mexicana causes chronic disease in C57BL/6 mice, in which cutaneous lesions persist for many months with high parasite burdens (10(7)–10(8) parasites). …”
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    Leishmania mexicana Infection Induces IgG to Parasite Surface Glycoinositol Phospholipids that Can Induce IL-10 in Mice and Humans
  6. 6
    “…We have recently demonstrated that MAP kinase phosphatase 2 (MKP-2) deficient C57BL/6 mice, unlike their wild-type counterparts, are unable to control infection with the protozoan parasite Leishmania mexicana. …”
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    T Cell Hypo-Responsiveness against Leishmania major in MAP Kinase Phosphatase (MKP) 2 Deficient C57BL/6 Mice Does Not Alter the Healer Disease Phenotype
  7. 7
    por Trujillo, Rafael, 1895-
    Publicado 1957
    “…bl.…”
    Libro
    Adolfo de la Huerta y los Tratados de Bucareli
  8. 8
    Publicado 1987
    “…Local cellular responses to cutaneous infection with Leishmania mexicana amazonensis were examined in susceptible (BALB/c) and resistant (C57BL/6) mouse strains by immunocytochemical and electron microscopic studies. …”
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    Cutaneous leishmaniasis. The defect in T cell influx in BALB/c mice
  9. 9
    “…In contrast, the comparison of C57BL/6_La-arg(-) vs. C57BL/6_La-WT revealed only 30 modulated transcripts, including some related to the immune response but none related to amino acid transport or l-arginine metabolism. …”
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    Dual transcriptome analysis reveals differential gene expression modulation influenced by Leishmania arginase and host genetic background
  10. 10
    Publicado 1993
    “…These events lead to outgrowth of either protective CD4+ T cells in the C57BL/6 mouse, which cures, or exacerbative cells in the BALB/c mouse, which succumbs to disease. …”
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    Leishmania major-specific, CD4+, major histocompatibility complex class II-restricted T cells derived in vitro from lymphoid tissues of naive mice
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