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  1. 51601
    “…Natural killer (NK) cells, the large granular lymphocytes differentiated from the common lymphoid progenitors, were discovered in early 1970’s. …”
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    The Role of Natural Killer Cells in Autoimmune Diseases
  2. 51602
    “…Compared to the serum of group NS, the serum of group S significantly induced hypercellularity, capsular thickening, and range of motion deficiency in mice shoulders after RCR. …”
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    The Serum from Patients with Secondary Frozen Shoulder Following Rotator Cuff Repair Induces Shoulder Capsule Fibrosis and Promotes Macrophage Polarization and Fibroblast Activation
  3. 51603
    “…This study sets the stage for more granular economic and social research on this growing phenomenon in American medicine. …”
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    A National Survey of postgraduate physician assistant fellowship and residency programs
  4. 51604
    “…The studies also highlights a male predominance of the disease but recent active surveillance suggested that macular form of PKDL shows female-predominance. It is recommended that along with passive case detection, active survey helps in early identification of cases, thus reducing disease transmission in the community. …”
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    Epidemiology of Post-Kala-azar Dermal Leishmaniasis
  5. 51605
    “…When PSI-362 was incorporated as a coating to the granular N fertilizer calcium ammonium nitrate and applied to barley crop, a coordinated stimulation of N uptake and assimilation markers was observed. …”
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    Reducing Nitrogen Input in Barley Crops While Maintaining Yields Using an Engineered Biostimulant Derived From Ascophyllum nodosum to Enhance Nitrogen Use Efficiency
  6. 51606
    “…METHODS: Real-time quantitative polymerase chain reaction (qRT-PCR) was used to detect the expression of miR-664a-3p in granulosa cells, granular tumor cell lines (KGN), and normal ovarian epithelial cell lines (IOSE80) in the polycystic ovary syndrome (PCOS) group and the control group. …”
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    MicroRNA-664a-3p inhibits the proliferation of ovarian granulosa cells in polycystic ovary syndrome and promotes apoptosis by targeting BCL2A1
  7. 51607
    “…The Latarjet procedure showed a lower degree of OA compared to non-operative treatment and the other operative procedures, except for the Bristow procedure and Rockwood capsular shift. The meta-analyses showed comparable development of OA over time among the treatment options. …”
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    Treatment type may influence degree of post-dislocation shoulder osteoarthritis: a systematic review and meta-analysis
  8. 51608
    Publicado 2021
    “…OBJECTIVE: This study aims to explore the clinical characteristics of T-cell large granular lymphocyte leukemia（T-LGLL）patients with STAT3 mutation status and provide a reference for clinical management of such patients. …”
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    STAT3基因突变的T细胞大颗粒淋巴细胞白血病临床特征研究
  9. 51609
    “…We compared the microvascular parameters between groups and explored their association with thickness of macular layers and clinical outcomes. Data were analyzed with General Estimating Equations (GEE) and adjusted for age, sex, and hypertension. …”
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    Foveal Remodeling of Retinal Microvasculature in Parkinson’s Disease
  10. 51610
    “…Pilot column tests using full-sized granular bone char particles can be used to assess treatment performance of fixed-bed contactors, but are costly, time consuming, and require large amounts of test water. …”
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    Modeling and experimental approaches for determining fluoride diffusion kinetics in bone char sorbent and prediction of packed-bed groundwater defluoridator performance
  11. 51611
    “…Accordingly, weaker granular degeneration, vacuolar degeneration, and nucleus deep staining were shown. …”
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    Tea Polyphenols Enhanced the Antioxidant Capacity and Induced Hsps to Relieve Heat Stress Injury
  12. 51612
    “…Surgeries on pathological myopia patients with macular hole retinal detachment were postponed in the COVID-19 pandemic. …”
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    The impact of the COVID-19 pandemic lockdown on rhegmatogenous retinal detachment services—Experiences from the Tongren eye center in Beijing
  13. 51613
    “…BACKGROUD: Treatment remains a challenge in massive and irreparable rotator cuff tears (RCTs), and superior capsular reconstruction (SCR) has become an increasingly popular choice. …”
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    Achilles Tendon Allograft for Superior Capsule Reconstruction in Irreparable Massive Rotator Cuff Tears
  14. 51614
    “…Significantly larger data sets with appropriate levels of granularity could produce more accurate results.…”
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    Traditional versus Microsphere Embolization for Hepatocellular Carcinoma: An Effectiveness Evaluation Using Data Mining
  15. 51615
    “…BACKGROUND: UTP-glucose-1-phosphoryl transferase (UGPase) catalyzes the synthesis of UDP-glucose, which is essential for generating the glycogen needed for the synthesis of bacterial lipopolysaccharide (LPS) and capsular polysaccharide, which play important roles in bacterial virulence. …”
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    Brucella melitensis UGPase inhibits the activation of NF-κB by modulating the ubiquitination of NEMO
  16. 51616
    “…Most identified colistin resistance usually involves modulation of lipid A that decreases or removes early charge-based interaction with colistin through up-regulation of multistep capsular polysaccharide expression. The membrane modifications occur by the addition of cationic phosphoethanolamine (pEtN) or 4-amino-l-arabinose on lipid A that results in decrease in the negative charge on the bacterial surface. …”
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    Current Update on Intrinsic and Acquired Colistin Resistance Mechanisms in Bacteria
  17. 51617
    “…BACKGROUND: MicroRNA (miRNA) play a significant role in the pathogenesis of complex neurodegenerative diseases including age-related macular degeneration (AMD), acting as post-transcriptional gene suppressors through their association with argonaute 2 (AGO2) - a key member of the RNA Induced Silencing Complex (RISC). …”
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    Functional microRNA targetome undergoes degeneration-induced shift in the retina
  18. 51618
    “…Moreover, α-carotene and β-carotene, the main carotenoids of carrots (Daucus carota) are precursors of vitamin A, whose deficiency in the diet can trigger night blindness and macular degeneration. With the aim of increasing the carotenoid content in fruit flesh, three key genes of the carotenoid pathway, phytoene synthase (DcPSY2) and lycopene cyclase (DcLCYB1) from carrots, and carotene desaturase (XdCrtI) from the yeast Xanthophyllomyces dendrorhous, were optimized for expression in apple and cloned under the Solanum chilense (tomatillo) polygalacturonase (PG) fruit specific promoter. …”
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    Daucus carota DcPSY2 and DcLCYB1 as Tools for Carotenoid Metabolic Engineering to Improve the Nutritional Value of Fruits
  19. 51619
    “…INTERPRETATION: Modulation of neoangiogenesis, in an analogous approach to those used to treat aberrant vascularization in cancer and also in the wet form of age-related macular degeneration (AMD), provides an alternative therapeutic strategy for intervention in AD that warrants clinical investigation.…”
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    Reversing pathology in a preclinical model of Alzheimer's disease by hacking cerebrovascular neoangiogenesis with advanced cancer therapeutics
  20. 51620
    “…INTRODUCTION: HIV planning requires granular estimates for the number of people living with HIV (PLHIV), antiretroviral treatment (ART) coverage and unmet need, and new HIV infections by district, or equivalent subnational administrative level. …”
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    Naomi: a new modelling tool for estimating HIV epidemic indicators at the district level in sub‐Saharan Africa
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