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1681por Weinberger, Daniel M., Trzciński, Krzysztof, Lu, Ying-Jie, Bogaert, Debby, Brandes, Aaron, Galagan, James, Anderson, Porter W., Malley, Richard, Lipsitch, Marc“…There are 91 known capsular serotypes of Streptococcus pneumoniae. The nasopharyngeal carriage prevalence of particular serotypes is relatively stable worldwide, but the host and bacterial factors that maintain these patterns are poorly understood. …”
Publicado 2009
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1682por Augustin, Albert“…RETAANE(®) 15mg (anecortave acetate suspension) is under investigation to treat exudative age-related macular degeneration (AMD), the single largest cause of blindness in the Western world, affecting over 15 million people in the USA. …”
Publicado 2006
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1683por Spitzer, Martin S, Ziemssen, Focke, Bartz-Schmidt, Karl U, Gelisken, Faik, Szurman, Peter“…Ranibizumab, a humanized antigen-binding fragment (Fab) that binds all isoforms of VEGF-A, significantly slows down loss of vision and causes significant visual improvement in many patients with choroidal neovascularization (CNV) due to exudative age-related macular degeneration (AMD). These benefits of intravitreal ranibizumab apply to all angiographic subtypes of neovascular AMD and across all lesion sizes when the drug is injected at monthly intervals as shown in two pivotal phase III trials (ANCHOR and MARINA). …”
Publicado 2008
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1684“…Diabetic retinopathy (DR) and diabetic macular edema (DME) are leading causes of blindness in the working-aged population of most developed countries. …”
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1685“…Some authors have reported its use in postoperative cystoid macular edema. Many of the studies on the use of TA in controlling intraocular inflammation and concomitant macular edema showed its effect to be transient in many patients requiring reinjection. …”
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1686“…PURPOSE: This essay reviews the experimental treatments and new imaging modalities that are currently being explored by investigators to help treat patients with age-related macular degeneration (AMD). DESIGN: Interpretative essay. …”
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1687“…In these refractory complicated cases the use of capsular flaps can represent a useful tool to save the implant and achieve definitive healing. …”
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1688“…Eight fresh-frozen knees were dissected, and the lateral soft tissues prepared into three distinct structures: a broad tissue band linking the iliotibial band (ITB) to the patella, and two capsular ligaments: patellofemoral and patellomeniscal. …”
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1689“…To retrospectively review our experience in infants with glanular hypospadias or hooded prepuce without meatal anomaly, who underwent circumcision with the plastibell device. …”
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1690“…Several computational models of the cerebellum have been proposed to explain the mechanisms of time representation, and they commonly point to the granular layer network. This article will review these computational models and discuss the possible computational power of the cerebellum.…”
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1691por Driessen, Niels J. B., Cox, Martijn A. J., Bouten, Carlijn V. C., Baaijens, Frank P. T.“…In this study, a framework is proposed to investigate remodelling of angular collagen fiber distribution in cardiovascular tissues. …”
Publicado 2007
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1692“…Fundus examination revealed macular holes and multiple areas of RPE hyperpigmentation in the periphery in both eyes. …”
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1693“…Indirect ophthalmoscopy and biomicroscopy revealed exudative macular edema as well as tumor-like telangiectatic vessels and exudation in temporal periphery. …”
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1694“…CONCLUSIONS: The transient beneficial effects of IVT on diabetic macular edema are not repeated with second injections. …”
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1695“…Granular cell tumor is a rare tumor of unknown etiology that more commonly affects the oral cavity but can also occur at other sites. …”
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1696“…Idiopathic eruptive macular pigmentation (IEMP) is a rather under-reported condition of unknown etiology. …”
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1697por Baas, Dominique C., Despriet, Dominiek D., Gorgels, Theo G. M. F., Bergeron-Sawitzke, Julie, Uitterlinden, André G., Hofman, Albert, van Duijn, Cornelia M., Merriam, Joanna E., Smith, R. Theodore, Barile, Gaetano R., ten Brink, Jacoline B., Vingerling, Johannes R., Klaver, Caroline C. W., Allikmets, Rando, Dean, Michael, Bergen, Arthur A. B.“…BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of irreversible visual loss in the developed countries and is caused by both environmental and genetic factors. …”
Publicado 2010
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1698por Parmalee, Nancy L., Schubert, Carl, Merriam, Joanna E., Allikmets, Kaija, Bird, Alan C., Gillies, Mark C., Peto, Tunde, Figueroa, Maria, Friedlander, Martin, Fruttiger, Marcus, Greenwood, John, Moss, Stephen E., Smith, Lois E.H., Toomes, Carmel, Inglehearn, Chris F., Allikmets, Rando“…PURPOSE: To find the gene(s) responsible for macular telangiectasia type 2 (MacTel) by a candidate-gene screening approach. …”
Publicado 2010
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1699“…Antivascular endothelial growth factor (anti-VEGF) therapies represent the standard of care for most patients presenting with neovascular (wet) age-related macular degeneration (neovascular AMD). Anti-VEGF drugs require repeated injections and impose a considerable burden of care, and not all patients respond. …”
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1700“…We report a 51-year-old Vietnam War veteran with an unusual variant of macular amyloidosis presenting as poikilodermatous skin lesions. …”
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