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Mostrando 1 - 20 Resultados de 1,051 Para Buscar 'corin.', tiempo de consulta: 0.18s Limitar resultados
  1. 1
    “…Genetic factors relate to corin remain unclear. The purpose of the current study was to comprehensively examine the associations among CORIN SNPs, methylations, serum corin levels and hypertension. …”
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    Associations between potentially functional CORIN SNPs and serum corin levels in the Chinese Han population
  2. 2
    “…Corin deficiency impairs fecal sodium excretion in mice. …”
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    Corin Deficiency Diminishes Intestinal Sodium Excretion in Mice
  3. 3
    “…It has been well documented that corin is a critical protease involved in the regulation of blood pressure and cardiac function. …”
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    Serum corin is associated with the risk of chronic heart failure
  4. 4
    “…The study aimed to determine whether corin may be a predictor of PE in a high-risk group—women with long-term PGDM. …”
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    Corin—The Early Marker of Preeclampsia in Pregestational Diabetes Mellitus
  5. 5
    “…In corin-deficient mice on normal- and high-salt diets, sweat and salt excretion is reduced. …”
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    The protease corin regulates electrolyte homeostasis in eccrine sweat glands
  6. 6
    “…The objective of this publication is to evaluate the results of TAA in a series of patients treated with corin system total ankle replacement METHODS: 26 TAA were implanted from Jan / 13 to Aug / 16, (26 patients - 15F: 58% / 11M: 42%) (mean age: 55 years: min 37a / max 69a) using the implants Zennith from Corin (UK). …”
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    Brazilian Experience with Zennith – Corin System Total Ankle Replacement
  7. 7
    “…We created corin conditional knockout (cKO), in which the Corin gene was selectively disrupted in the kidney (kcKO) or heart (hcKO). …”
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    Renal Corin Is Essential for Normal Blood Pressure and Sodium Homeostasis
  8. 8
    “…INTRODUCTION: Corin is a protease in the natriuretic peptide system. …”
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    Corin deficiency impairs cardiac function in mouse models of heart failure
  9. 9
    “…Corin is a protease that activates atrial natriuretic peptide, a cardiac hormone important in the control of blood pressure and salt-water balance. …”
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    Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice
  10. 10
    “…It remains unknown if corin has a role in regulating adipose tissue function. …”
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    Corin Deficiency Alters Adipose Tissue Phenotype and Impairs Thermogenesis in Mice
  11. 11
    por Lee, Sun Jung, Lee, Dong Hee, Kim, Ha Won
    Publicado 2020
    “…Activated corin cleaves pro-ANP to ANP, which regulates water–sodium balance and lowers blood pressure. …”
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    Novel Antihypertension Mechanism of β-Glucan by Corin and ANP-Mediated Natriuresis in Mice
  12. 12
    “…BACKGROUND: Corin is a transmembrane protease that activates ANP and BNP (atrial and B‐type natriuretic peptides). …”
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    Recombinant Soluble Corin Improves Cardiac Function in Mouse Models of Heart Failure
  13. 13
    “…Corin deficiency prevents ANP activation and causes hypertension and heart disease. …”
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    Corin: A Key Mediator in Sodium Homeostasis, Vascular Remodeling, and Heart Failure
  14. 14
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    Falling corin and ANP activity levels accelerate development of heart failure and cardiac fibrosis
  15. 15
    “…Altered expression of corin, a cardiac transmembrane serine protease, has been linked to dilated and ischemic cardiomyopathy. …”
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    Corin Overexpression Reduces Myocardial Infarct Size and Modulates Cardiomyocyte Apoptotic Cell Death
  16. 16
    “…RESULTS: The final diagnostic model included age, sex, cigarette smoking, family history of stroke, history of hypertension, systolic blood pressure, total cholesterol, high-density lipoprotein cholesterol, fasting glucose, and serum corin. The diagnostic model exhibited good discrimination in both training (AUC: 0.910, 95% CI: 0.884–0.936) and testing (AUC: 0.907, 95% CI: 0.881–0.934) samples. …”
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    A Prediction Model for Rapid Identification of Ischemic Stroke: Application of Serum Soluble Corin
  17. 17
    “…In conclusion, acute myocardial infarction induces rapid increases in plasma corin and decreases in cardiac corin levels. In the early phase of acute myocardial infarction, plasma corin levels are inversely correlated with heart function and may reflect the severity of myocardial damage.…”
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    Increases in plasma corin levels following experimental myocardial infarction reflect the severity of ischemic injury
  18. 18
    “…MicroRNAs (miRNAs) are pervasive regulators of gene expression, but their potential role in regulating corin activity has not been elucidated. Our aim was to systematically identify and characterize miRNA regulators of corin activity in human cardiomyocytes. …”
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    Functional Screening Identifies MicroRNA Regulators of Corin Activity and Atrial Natriuretic Peptide Biogenesis
  19. 19
    “…INTRODUCTION: Proprotein convertase subtilisin/kexin-6 (PCSK6) is a secretory protein that activates corin in the heart. Higher circulating levels of corin are associated with improved cardiovascular outcomes in patients with acute myocardial infarction. …”
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    Serum PCSK6 and corin levels are not associated with cardiovascular outcomes in patients undergoing coronary angiography
  20. 20
    por Kitamura, Mitsunobu
    Publicado 2022
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    Upstream Enzyme of Natriuretic Peptide Pathway: Is Soluble Corin a Predictor of Future Stroke Events?
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