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381por Bumke-Vogt, Christiane, Osterhoff, Martin A., Borchert, Andrea, Guzman-Perez, Valentina, Sarem, Zeinab, Birkenfeld, Andreas L., Bähr, Volker, Pfeiffer, Andreas F. H.“…The flavones apigenin (4′,5,7,-trihydroxyflavone) and luteolin (3′,4′,5,7,-tetrahydroxyflavone) are plant secondary metabolites with antioxidant, antiinflammatory, and anticancer activities. …”
Publicado 2014
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382“…Under the optimal conditions, 151 μg/g luteolin and 104 μg/g apigenin were extracted from the tree peony pod. …”
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383por Cook, Matthew T., Liang, Yayun, Besch-Williford, Cynthia, Goyette, Sandy, Mafuvadze, Benford, Hyder, Salman M.“…Furthermore, LU blocked MPA-induced acquisition of stem cell-like properties by breast cancer cells. CONCLUSIONS: Luteolin effectively blocks progestin-dependent human breast cancer tumor growth and the stem cell-like phenotype in human breast cancer cells.…”
Publicado 2015
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384“…However, some flavonoids such as luteolin may have the potential to induce cytotoxicity in osteoblast-like cells. …”
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385por Paterniti, Irene, Impellizzeri, Daniela, Di Paola, Rosanna, Navarra, Michele, Cuzzocrea, Salvatore, Esposito, EmanuelaEnlace del recurso
Publicado 2016
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386por Zang, Ming-de, Hu, Lei, Fan, Zhi-yuan, Wang, He-xiao, Zhu, Zheng-lun, Cao, Shu, Wu, Xiong-yan, Li, Jian-fang, Su, Li-ping, Li, Chen, Zhu, Zheng-gang, Yan, Min, Liu, Bing-ya“…The effects of luteolin on GC cells and their underlying mechanisms remain unclear. …”
Publicado 2017
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387por Guo, Ying-fang, Xu, Nian-nian, Sun, Weijing, Zhao, Yifan, Li, Cheng-ye, Guo, Meng-yao“…We evaluated the anti-inflammatory effects and mechanism of luteolin, a natural flavonoid with a wide range of pharmacological activities, in a mouse model of S. aureus mastitis. …”
Publicado 2017
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388por Marín, Laura, Gutiérrez-del-Río, Ignacio, Yagüe, Paula, Manteca, Ángel, Villar, Claudio J., Lombó, Felipe“…In the cases of eriodictyol and luteolin, their production in this important type of biotechnology-prone bacteria, the actinomycetes, had not been described in the literature yet.…”
Publicado 2017
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389“…In addition, luteolin combined with LY294002 markedly increased the Bax/Bcl-2 ratio, while when combined with U0126, luteolin had less effects on the Bax/Bcl-2 ratio compared with luteolin treatment alone, suggesting that both the MAPK and PI3K signaling pathways are involved in the apoptosis induced by luteolin. …”
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390“…The aim of the present study was to investigate the underlying molecular mechanisms of the potent cell cycle inhibition and apoptotic effect of luteolin on LoVo human colon cancer cells. In the present study, Cell Counting kit-8 assay revealed that luteolin exerted notable cytotoxicity on LoVo cells in a dose- and time-dependent manner, with a 50% inhibitory concentration value of 66.70 and 30.47 µmol/l at the time points of 24 and 72 h, respectively. …”
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391por Xiao, Boduan, Qin, Yun, Ying, Chang, Ma, Buyun, Wang, Binrong, Long, Fei, Wang, Ruwei, Fang, Ling, Wang, Yigang“…In recent years, oncolytic viruses have attracted increasing interest due to their potent antitumor effects. Luteolin, a natural product, has additionally been observed to exhibit various pharmacological antitumor activities. …”
Publicado 2017
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392“…This current study aimed to elucidate the effects and possible underlying mechanisms of long-term supplementation with dietary luteolin (LU)-enriched artichoke leaf (AR) in high-fat diet (HFD)-induced obesity and its complications (e.g., dyslipidemia, insulin resistance, and non-alcoholic fatty liver disease) in C57BL/6N mice. …”
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393“…LD50 of PFE and luteolin was 540 mg/kg and 150 mg/kg, respectively. …”
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394por Pu, Yansong, Zhang, Tao, Wang, Jianhua, Mao, Zhijun, Duan, Baojun, Long, Yanbin, Xue, Fei, Liu, Dong, Liu, Sida, Gao, Zengzhan“…However, the detail mechanisms of luteolin on GC are poorly understood. Here, we investigated the anticancer effect of luteolin in GC cells in vitro and in vivo. …”
Publicado 2018
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395por Wu, Wanling, Li, Dongye, Zong, Yu, Zhu, Hong, Pan, Defeng, Xu, Tongda, Wang, Tao, Wang, Tingting“…Luteolin (Lut) is a common dietary flavonoid present in Chinese herbal medicines that has been reported to have important anti-inflammatory properties. …”
Publicado 2013
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396por Palombo, Ramona, Caporali, Sabrina, Falconi, Mattia, Iacovelli, Federico, Morozzo Della Rocca, Blasco, Lo Surdo, Alessandro, Campione, Elena, Candi, Eleonora, Melino, Gerry, Bernardini, Sergio, Terrinoni, Alessandro“…Recently, it has been demonstrated that luteolin, in the form of Luteolin-7-O-β-d-glucoside (LUT-7G) is able to induce the keratinocyte differentiation process in vitro. …”
Publicado 2019
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397“…BACE1 inhibitory conjugates derived from two natural products, luteolin (1) and p-hydroxy-cinnamic acid (2), were subjected to systematic structure modifications, including various positions in luteolin segment for conjugation, different linkers (length, bond variation), as well as various substitutions in cinnamic acid segment (various substituents on benzene, and replacement of benzene by heteroaromatics and cycloalkane). …”
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398por Tan, Xin, Yang, Yi, Xu, Jianguo, Zhang, Peng, Deng, Ruming, Mao, Yiguang, He, Jia, Chen, Yibin, Zhang, Yan, Ding, Jiasheng, Li, Haiying, Shen, Haitao, Li, Xiang, Dong, Wanli, Chen, Gang“…Luteolin treatment effectively alleviated brain edema and ameliorated neurobehavioral dysfunction and memory loss in vivo. …”
Publicado 2020
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399“…Three flavonoids derived from the leaves of Capsicum chinense Jacq. were identified as chrysoeriol (1), luteolin-7-O-glucopyranoside (2), and isorhamnetin-7-O-glucopyranoside (3). …”
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400por Che, Denis Nchang, Cho, Byoung Ok, Kim, Ji-su, Shin, Jae Young, Kang, Hyun Ju, Jang, Seon Il“…Here, we investigated the effects of apigenin and luteolin on the production of IL-31 and IL-33 by microglia cells. …”
Publicado 2020
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