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501por Shadrack, Daniel M., Deogratias, Geradius, Kiruri, Lucy W., Onoka, Isaac, Vianney, John-Mary, Swai, Hulda, Nyandoro, Stephen S.“…The findings suggest that luteolin could be potent blocker of SARS-CoV-2 cell entry. …”
Publicado 2021
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502por Rajput, Shahid Ali, Shaukat, Aftab, Wu, Kuntan, Rajput, Imran Rashid, Baloch, Dost Muhammad, Akhtar, Rana Waseem, Raza, Muhammad Asif, Najda, Agnieszka, Rafał, Papliński, Albrakati, Ashraf, El-Kott, Attalla F., Abdel-Daim, Mohamed M.“…Group 3, treated with 50 mg/kg BW luteolin (LUTN), and Group 4, treated with 0.75 mg/kg BW aflatoxin B(1) + 50 mg/kg BW luteolin (AFB(1) + LUTN). …”
Publicado 2021
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503por Liu, Qun, Li, Li, Cheng, Haitao, Yao, Lixiang, Wu, Jie, Huang, Hui, Ning, Wei, Kai, Guoyin“…The TabHLH1 transcript was highly induced by salt stress, and the TabHLH1 protein was localized in the nucleus. CGA and luteolin concentrations in TabHLH1-overexpression transgenic lines were significantly higher than those in the wild type, while CGA and luteolin concentrations in TabHLH1-RNA interference (RNAi) transgenic lines were significantly lower. …”
Publicado 2021
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504por Zhou, Yuan, Wu, Rong, Cai, Fei-fei, Zhou, Wen-Jun, Lu, Yi-Yu, Zhang, Hui, Chen, Qi-Long, Sun, Ming-Yu, Su, Shi-Bing“…RESULTS: According to the network XYS-Syndrome-liver fibrosis network, 8 key compounds and 255 combinations were predicted from in XYS. Luteolin, licochalcone A, aloe-emodin and acacetin formula (LLAAF) had a synergistic effect on the proliferation inhibition of hepatic stellate cells compared to individual compounds alone. …”
Publicado 2021
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505por Xie, Yi-Zi, Peng, Chen-Wen, Su, Zu-Qing, Huang, Hui-Ting, Liu, Xiao-Hong, Zhan, Shao-Feng, Huang, Xiu-Fang“…We aimed to evaluate the possibility of luteolin evolving into an ideal drug and explore the underlying molecular mechanisms of luteolin against COVID-19/asthma comorbidity. …”
Publicado 2022
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506por Gong, Benxin, Zheng, Ying, Li, Jiahua, Lei, Huafeng, Liu, Kexin, Tang, Jingyun, Peng, Yanrong“…Hsa_circ_0001326 expression was upregulated in luteolin treat THP-1 derived macrophages. Silence of hsa_circ_0001326 reversed the function of luteolin on macrophages polarization. …”
Publicado 2022
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507“…The present study aims to investigate the effects of ultrasound on the non-covalent interaction of β-lactoglobulin (β-LG) and luteolin (LUT) and to investigate the relationship between allergenicity and human intestinal microbiota. …”
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508“…Multidrug resistance (MDR) remains a critical bottleneck in successful treatment of osteosarcoma (OS). Luteolin is a flavonoid compound that has been verified to increase the sensitivity to antineoplastic drugs in many tumors. …”
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509por Facchinetti, Roberta, Valenza, Marta, Gomiero, Chiara, Mancini, Giulia Federica, Steardo, Luca, Campolongo, Patrizia, Scuderi, Caterina“…We also tested the potential beneficial effect of the anti-inflammatory and neuroprotective composite palmitoylethanolamide and luteolin (co-ultra PEALut), which is known to engage the isoform alfa of the PPARs. …”
Publicado 2022
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510por Jiang, Yuhui, Yang, Wenjuan, Ding, Jiameng, Ji, Jie, Wu, Liwei, Zheng, Yuanyuan, Li, Yan, Cheng, Ziqi, Zhang, Jie, Yu, Qiang, Feng, Jiao, Li, Jingjing, Wu, Jianye, Zhou, Yingqun, Guo, Chuanyong“…BALB/c mice were randomly divided into six groups, including normal controls (NC), luteolin (50 mg/kg), sham procedure, IR+25 mg/kg luteolin, and IR+50 mg/kg luteolin group. …”
Publicado 2022
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511por Ryu, Dajung, Jee, Hye-Jin, Kim, Sang-Yoon, Hwang, Seung-Hwan, Pil, Gam-Bang, Jung, Yi-Sook“…Because of the limitations of classical antidepressants such as side effects, low efficacy, and difficulty in long-term use, new natural medicines and bioactive molecules from plants with greater safety and efficacy have recently attracted attention. Luteolin-7-O-glucuronide (L7Gn), a bioactive molecule present in Perilla frutescens, is known to alleviate severe inflammatory responses and oxidative stress in macrophages. …”
Publicado 2022
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512por Gutiérrez, Rosa Martha Pérez, Gómez, Julio Téllez, Urby, Raúl Borja, Soto, José G Contreras, Parra, Héctor Romo“…The absence of a treatment efficient in the control of type 2 diabetes mellitus requires more functional products to assist treatment. Luteolin (LU) and diosmin (DIO) have been known as bioactive molecules with potential for the treatment of diabetes. …”
Publicado 2022
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513“…In addition, the measurement of apoptosis in PIG1 cells and intracellular reactive oxygen species were measured using quercetin (QU), luteolin (LU), and kaempferol (KA) to protect melanocytes from oxidative stress. …”
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514por Xie, Mingxia, Wang, Hanqing, Gao, Tiantian, Peng, Jun, Meng, Pan, Zhang, Xi, Guo, Dongwei, Liu, Guangya, Shi, Jian, Peng, Qinghua“…Luteolin has been reported to exhibit therapeutic effect on depressive-like behaviors in mice. …”
Publicado 2023
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515por Yu, Yaping, Ding, Shun, Xu, Xiaoqing, Yan, Dongming, Fan, Yonghao, Ruan, Banzhan, Zhang, Xiaodian, Zheng, Liping, Jie, Wei, Zheng, Shaojiang“…PURPOSE: This study aimed to explore the pharmacological mechanism of Dangshen (Codonopsis pilosula) against hepatocellular carcinoma (HCC) based on network pharmacology and bioinformatics, and to verify the anticancer effect of luteolin, the active ingredient of Codonopsis pilosula, on HCC cells. …”
Publicado 2023
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517por Wu, Ling, Lin, Yingda, Gao, Songyu, Wang, Yongfang, Pan, Huiji, Wang, Zhaozhi, Pozzolini, Marina, Yang, Fengling, Zhang, Haiyan, Yang, Yi, Xiao, Liang, Xu, Yuan“…Finally, in vivo mouse tumor models were constructed to further confirm the effects of luteolin on TNBC. Results: Luteolin dramatically suppressed cell proliferation, invasion, and migration while favoring cell apoptosis in a dose- and time-dependent manner. …”
Publicado 2023
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518por Chen, Rui, Hollborn, Margrit, Grosche, Antje, Reichenbach, Andreas, Wiedemann, Peter, Bringmann, Andreas, Kohen, Leon“…We compared the effects of various bioflavonoids (epigallocatechin-3-gallate [EGCG], luteolin, apigenin, myricetin, quercetin, and cyanidin) on the physiological properties and viability of cultured human retinal pigment epithelial (RPE) cells. …”
Publicado 2014
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519por Yang, Daqian, Tan, Xiao, Lv, Zhanjun, Liu, Biying, Baiyun, Ruiqi, Lu, Jingjing, Zhang, Zhigang“…Here we hypothesized that luteolin would attenuate hepatotoxicity induced by acute inorganic mercury exposure. …”
Publicado 2016
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520“…A simple and sensitive HPLC-UV method has been developed for the simultaneous determination of quercetin, luteolin, and apigenin in rat plasma after oral administration of Matricaria chamomilla L. extract. …”
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