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  1. 6001
    “…To this end, different bioactive molecules, including hyaluronic acid (HA), folic acid (FA), and polyethylene glycol (PEG), were used and compared for surface modification of niosomes to enhance endocytosis. …”
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    Folic Acid-Decorated pH-Responsive Nanoniosomes With Enhanced Endocytosis for Breast Cancer Therapy: In Vitro Studies
  2. 6002
    “…We show that targeting PDGF-Rα/β with CP-673451 in vitro triggers outgrowth of neurite-like processes in GBM cell lines and GBM stem cells (GSCs), suggesting differentiation into neural-like cells, while reducing proliferation and invasion in 3D hyaluronic acid hydrogels. In addition, we report that treatment with CP-673451 improves the anti-tumour effects of temozolomide in vivo using a subcutaneous xenograft mouse model. …”
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    PDGF-R inhibition induces glioblastoma cell differentiation via DUSP1/p38(MAPK) signalling
  3. 6003
    “…Detection of the expression of lymphatic vessel endothelial hyaluronic acid receptor-1 (LYVE-1), Podoplanin, vascular endothelial growth factor receptor-3 (VEGFR-3) and VEGF C to investigate lymphangiogenesis. …”
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    Eplerenone ameliorates lung fibrosis in unilateral ureteral obstruction rats by inhibiting lymphangiogenesis
  4. 6004
    “…In this work, we have developed a liquid chromatography (LC) mass spectrometry (MS) methodology that allows the quantification of all the components of a series of NCs prepared by different techniques, namely dl-α-tocopherol; d-α-tocopherol polyethylene glycol 1000 succinate; benzethonium; lecithin; hexadecyltrimethylammonium; 1,2-dioleoyl-3-trimethylammoniumpropane; caprylic/capric triglycerides; macrogol 15-hydroxystearate; polysorbate 80; polysialic acid; hyaluronic acid; and polyethylene glycol polyglutamic acid. …”
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    Quantification of the actual composition of polymeric nanocapsules: a quality control analysis
  5. 6005
    “…BACKGROUND: Diclofenac etalhyaluronate (DF-HA) is a recently developed analgesic conjugate of diclofenac and hyaluronic acid that has analgesic and anti-inflammatory effects on acute arthritis. …”
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    Analgesic effects and arthritic changes following intra-articular injection of diclofenac etalhyaluronate in a rat knee osteoarthritis model
  6. 6006
    “…Many graphs have been utilized to gain understanding into the problem’s various characteristics including velocity and concentration, among others. Hyaluronate (HA) is considered to be present in porous cartilage surfaces and the viscosity of synovial fluid fluctuates in response to the amount of HA present.…”
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    Significance of Brinkman and Stokes system conjuncture in human knee joint
  7. 6007
    “…FINDINGS / RESULTS: CSE significantly decreased joint swelling, pain behaviors, and serum levels of TNF-α, IL6, hyaluronic acid, and CTX-II. The radiographic findings revealed almost normal joint space with normal radiodensity and diameter in CSE-treated rats. …”
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    Crataegus sinaica defatted methanolic extract ameliorated monosodium iodoacetate-induced oxidative stress andinhibited inflammation in a rat model of osteoarthritis
  8. 6008
    “…BACKGROUND: Hyaluronic acid (HA) soft tissue fillers are used to restore volume loss to the lips and perioral area. …”
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    Safe and Effective Lip Enhancement with VYC-15L in Chinese Adults
  9. 6009
    “…INTRODUCTION: Peptide‐C ampoules (PC) contain peptides, 10% of vitamin C, hyaluronic acid, and Vichy volcanic mineralizing water. …”
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    Topical formulation containing peptides and vitamin C in ampoules improves skin aging signs: Results of a large, international, observational study
  10. 6010
    “…The purpose of this study was to develop poloxamer (P407)-based in-situ thermogellable hydrogels with reducing concentration of P407 by adding hypromellose (HPMC) and with enhancing mucoadhesion of resulting hydrogels by adding hyaluronic acid (HA) for prolonging ocular delivery of hydroxypropyl-β-cyclodextrin (HPβCD)-solubilized testosterone (TES). …”
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    Poloxamer sols endowed with in-situ gelability and mucoadhesion by adding hypromellose and hyaluronan for prolonging corneal retention and drug delivery
  11. 6011
    “…Various nanostructures, including lipid‐, carbon‐, polymeric‐ and metal‐based nanoparticles, are modifiable with CS for DOX delivery, while functionalization of CS‐NPs with ligands such as hyaluronic acid promotes selectivity toward tumor cells and prevents DOX resistance. …”
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    Chitosan‐based nanoscale systems for doxorubicin delivery: Exploring biomedical application in cancer therapy
  12. 6012
    “…Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with intrathecal administration of low- and high-molecular-weight contrast agents (Gd-DTPA and hyaluronic acid conjugated Gd-DTPA) was performed after TBI and head temperature management. …”
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    Hypothermia impairs glymphatic drainage in traumatic brain injury as assessed by dynamic contrast-enhanced MRI with intrathecal contrast
  13. 6013
    “…INTRODUCTION: Autologous mesenchymal stem cells (MSC) implantation suspended in hyaluronic acid (HA) has been proven to delay worsening of articular cartilage degeneration in the knee joint. …”
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    Intra-articular injection of human umbilical cord-derived mesenchymal stem cells in sheep models of meniscectomy-induced osteoarthritis: An experimental study
  14. 6014
    “…Then, two novel aldol reactions, condensing D-erythrose 4-phosphate and glycolaldehyde (GALD) into 2R,3R-stereo allose 6-phosphate by DeoC or 2S,3R-stereo altrose 6-phosphate by TalB(F178Y)/Fsa, were identified for the first time. …”
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    Non-natural Aldol Reactions Enable the Design and Construction of Novel One-Carbon Assimilation Pathways in vitro
  15. 6015
    “…She was given 5 mg intravenous dexamethasone, cetirizine 10 mg, and clindamycin 300 mg by the dermatologist. We gave hyaluronic acid 0.025% mouthwash for oral ulcers and petroleum jelly for the lips. …”
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    A Rare Case of COVID-19-Induced Acute Exacerbation of Oral Dermatitis Herpetiformis in a Geriatric Patient
  16. 6016
    “…Urinary glycosaminoglycan (GAG) analysis revealed increased heparan, dermatan sulphates, and hyaluronic acid. We showed decreased abundance of VPS33A in patient derived fibroblasts and provided evidence that the p.Arg200Pro mutation leads to destablization of the protein and proteasomal degradation. …”
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    Juvenile mucopolysaccharidosis plus disease caused by a missense mutation in VPS33A
  17. 6017
    “…There was also a significant increase in the level of hyaluronic acid (HA) in betamethasone‐injected VFs in comparison to the saline‐injected VFs (p = .006). …”
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    Effects of compound betamethasone on vocal fold wound healing in rabbit model: A preliminary study
  18. 6018
    “…The included studies reported favorable efficacy and safety outcomes for intralesional jet injector-assisted treatment with triamcinolone acetonide/hexacetonide, 5-fluorouracil, bleomycin, or hyaluronic acid. Two high-quality studies showed good efficacy and tolerability of intralesional jet injections with a combination of 5-fluorouracil and triamcinolone acetonide in hypertrophic scars and with saline in boxcar and rolling acne scars. …”
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    Efficacy and safety of needle-free jet injector-assisted intralesional treatments in dermatology—a systematic review
  19. 6019
    “…Hyaluronan synthase-2 (HAS-2) is a key enzyme in synthesizing hyaluronic acid (HA) in vivo. The synthesis of high molecular weight HA catalyzed by HAS-2 serves a vital role in joint movement and homeostasis; however, it is unclear what important role HAS-2 plays in maintaining chondrocyte cytoskeleton morphology and in cartilage degeneration. …”
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    Downregulation of HAS-2 regulates the chondrocyte cytoskeleton and induces cartilage degeneration by activating the RhoA/ROCK signaling pathway
  20. 6020
    “…Finally, ProtheraCytes(®) survive after injection into the knee of a collagenase-induced osteoarthritis mouse model, engrafting mainly in the synovial membrane, probably due to the fact that ProtheraCytes(®) express CD44, a receptor of hyaluronic acid, which is abundantly present in the synovial membrane. …”
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    Evaluation of expanded peripheral blood derived CD34+ cells for the treatment of moderate knee osteoarthritis
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