“…Instead, we delivered plasmids encoding neuronal transcription factors (Brn2, Ascl1, Myt1l) to primary mouse embryonic fibroblasts with a bioreducible linear poly(amido amine). The low toxicity and high transfection efficiency of this gene carrier allowed repeated dosing to sustain high transgene expression levels. …”
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“…Surprisingly, 4 adopts a solvent-separated ion pair arrangement in contrast to the contacted ion variants of 3-ortho and 3-meta. Aided by DFT calculations on model systems, discussion focuses on the different basicities, amido or alkyl, and steps, exhibited in these reactions, and how the structures and bonding within these isolated key metallic intermediates (prior to any electrophilic interception step), specifically the interactions involving the alkali metal, influence the regioselectivity of the Zn−H exchange process.…”
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“…An ester linkage, rather than an amido one, was found to be optimal for neuritogenic activity. …”
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“…The semi-synthetic in vitro system we use include common cationic DNA-compacting agents, poly(amido amine) (PAMAM) dendrimers and the surfactant hexadecyltrimethylammonium bromide (CTAB), which we apply to linearized plasmid DNA encoding for the luciferase reporter gene. …”
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“…The structure clearly shows the mer-η(4) O,O,N,N-binding mode of the N,N′-bis-(2-cyano-ethyl­propeno­yl)-1,2-di­amido­benzene ligand stabilizing the Zn centre of a distorted octa­hedral environment. …”
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“…High-temperature-mediated hypocotyl elongation additionally involves localized changes in auxin metabolism, mediated by the indole-3-acetic acid (IAA)-amido synthetase Gretchen Hagen 3 (GH3).17 [10]. …”
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“…The objectives of this study were to: (1) develop a bioactive multifunctional composite (BMC) via nanoparticles of amorphous calcium phosphate (NACP), 2-methacryloyloxyethyl phosphorylcholine (MPC), dimethylaminohexadecyl methacrylate (DMAHDM) and nanoparticles of silver (NAg); and (2) investigate the effects of combined BMC + poly (amido amine) (PAMAM) on remineralization of demineralized root dentin in a cyclic artificial saliva/lactic acid environment for the first time. …”
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“…In this study, we investigated the potential value of amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides (ASOs) targeting YB-1 (YB-1 ASO(A)) as an antiangiogenic cancer therapy. …”
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“…Reported here are mechanistic and computational studies of CS(2) release from a series of dithiocarbamate anions (DTCs), where R(2)N represents several different secondary amido groups. The various DTCs under physiologically relevant conditions show a tremendous range of reactivities toward CS(2) dissociation with decay lifetimes ranging from ∼2 s for imidazolidyldithiocarbamate (ImDTC(–)) to ∼300 s for diisopropyldithiocarbamate (DIDTC(–)) to >24 h for pyrrolidinyldithiocarbamate (PDTC(–)) in pH 7.4 phosphate buffer solution at 37 °C. …”
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“…Also, presence of odorous substances (toiletries, fruits, dirty clothes, etc.), water, and amido-bond-containing organic compounds (typical organic amines, legal drugs, and different amino acids) shows little effect upon the sensing. …”
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“…Although IOX did not decolorize any dyes in the absence of redox mediator, significant decolorization of Orange G, Indigo Carmine, Amido Black, and Remazol Brilliant Blue R (RBBR) was observed in the presence of iodide. …”
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“…Available experimental results were indecisive regarding the amido‐group binding in the Cu(II) equatorial plane in solutions, but the examination of the relative stability of Cu(l‐Asn)(2) conformers in 30 binding modes confirms the glycine‐like mode as the most stable one. …”
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“…Under the catalysis of HOBT/EDCL, the mono-amido-functionalized pillar[5]arenes were amidated with ferrocene carboxylic acid to constructed ferrocene-based [1]rotaxanes, respectively. …”
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“…To obtain a high-efficiency drug and gene co-delivery system to HNE-1 tumor therapy, a polymeric prodrug (PAAs-MTX) with chemotherapeutic sensibilization was synthesized consisting of a GSH-response hyperbranched poly(amido amine) (PAAs) and an antitumor drug of methotrexate (MTX). …”
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“…[Image: see text] The redox noninnocence of the TAML scaffold in cobalt-TAML (tetra-amido macrocyclic ligand) complexes has been under debate since 2006. …”
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“…[Image: see text] The intrinsically fluorescent highly hydrophilic multifunctional aliphatic terpolymer, maleic acid (MA)-co-2-(N-(hydroxymethyl)acrylamido)succinic acid (NHASA)-co-N-(hydroxymethyl)acrylamide (NHMA), that is, 1, was designed and synthesized via C–C/N–C-coupled in situ allocation of a fluorophore monomer, that is, NHASA, composed of amido and carboxylic acid functionalities in the polymerization of two nonemissive MA and NHMA. …”
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“…The peptide nanoassemblies were formed by self-assembly of a newly synthesized peptide bolaamphiphile bis(N-α-amido-threonine) 1,7 heptane dicarboxylate (ThrC7). …”
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“…A series of 17 compounds (12–16 b) with 2,4,5-trisubstitutedthiazole scaffold having 5-aryl group, 4-carboxylic acid/ester moiety, and 2-amino/amido/ureido functional groups were synthesised, characterised, and evaluated for their carbonic anhydrase (CA)-III inhibitory activities using the size exclusion Hummel–Dreyer method (HDM) of chromatography. …”
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“…Data is citable and archived persistently, providing a comprehensive embodiment of entire simulation pipelines (calculations performed, codes used, data generated) in the form of graphs that allow retracing and reproducing any computed result. When an AiiDA database is shared on Materials Cloud, peers can browse the interconnected record of simulations, download individual files or the full database, and start their research from the results of the original authors. …”
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“…Strong N‐to‐Ga π donation from the amido substituent is reflected in a very short N−Ga distance (1.961(2) Å), while the P⋅⋅⋅Ga contact (3.076(1) Å) is well outside the sum of the respective covalent radii. …”
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