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13241“…[Image: see text] A series of Mn(II), Fe(II), and Co(II) bisaryloxide dimers ([M(OC(6)H(2)-2,4,6-Cy(3))(2)](2) {M = Mn (1), Fe (2), and Co (3)} were synthesized by the addition of 2,4,6-tricyclohexylphenol (HOC(6)H(2)-2,4,6-Cy(3)) to the silyl amido dimers [M(N(SiMe(3))(2))(2)](2) (M = Mn, Fe, Co; Cy = cyclohexyl). …”
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13242por Waller, Spenser, Powell, Avery, Noel, Randi, Schueller, Michael J., Ferrieri, Richard A.“…Furthermore, radiocarbon flux analysis revealed that ‘new’ carbon partitioning (as (11)C) into the (11)C-radiolabeled amino acid (AA) pool was significantly reduced with HT stress as were yields of [(11)C]-aspartic acid, an important AA in nicotine biosynthesis, and its beta-amido counterpart [(11)C]-asparagine. In contrast, [(12)C]-aspartic acid levels appeared unaffected at 38 °C but were elevated at 43 °C relative to controls. [(12)C]-Asparagine levels were noted to be elevated at both stress temperatures. …”
Publicado 2023
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13243“…Inosine-monophosphate dehydrogenase apparently is a target site of the compounds; similar effects on phosphoribosyl-pyrophosphate amido transferase, orotidine-monophosphate decarboxylase, and both nucleoside and nucleotide kinases were observed. …”
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13244“…METHODS: SV119 was covalently linked with polyethylene glycol-dioleyl amido aspartic acid conjugate (PEG-DOA) to generate a novel functional lipid, SV119-PEG-DOA. …”
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13245por Ahmad Wani, Naiem, Gupta, Vivek K., Kant, Rajni, Aravinda, Subrayashastry, Rai, Rajkishor“…N-Protected derivatives of 1-aminocyclohexaneacetic acid (β(3,3)-Ac(6)c), namely Valeroyl-β(3,3)-Ac(6)c-OH [2-(1-pentanamidocyclohexyl)acetic acid, C(13)H(23)NO(3)], (I), Fmoc-β(3,3)-Ac(6)c-OH [2-(1-{[(9H-fluoren-9-yloxy)carbonyl]amino}cyclohexyl)acetic acid, C(23)H(25)NO(4)], (II), and Pyr-β(3,3)-Ac(6)c-OH {2-[1-(pyrazine-2-amido)cyclohexyl]acetic acid, C(13)H(17)N(3)O(3)}, (III), were synthesized and their conformational properties were determined by X-ray diffraction analysis. …”
Publicado 2014
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13246por Barb, Adam W.“…UDP-[(13)C,(15)N]GlcNAc was synthesized enzymatically in a one-pot reaction from [(13)C]glucose and [(15)N-amido]glutamine. Modifying Fc with recombinantly expressed glycosyltransferases (Gnt1 and Gnt2) and UDP-[(13)C,(15)N]GlcNAc resulted in complete glycoform conversion as judged by mass spectrometry. …”
Publicado 2014
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13247“…In this study, we investigated the effects of aerobic training on the expression of AdipoR1 and AidpoR2 mRNAs in PBMCs, whole body insulin sensitivity, and circulating adiponectins in men. …”
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13248por Valiente, Esmeralda, Bouché, Laura, Hitchen, Paul, Faulds-Pain, Alexandra, Songane, Mario, Dawson, Lisa F., Donahue, Elizabeth, Stabler, Richard A., Panico, Maria, Morris, Howard R., Bajaj-Elliott, Mona, Logan, Susan M., Dell, Anne, Wren, Brendan W.“…We show that the glycosyltransferases 1 and 2 (GT1 and GT2) are responsible for the sequential addition of a GlcNAc and two rhamnoses, respectively, and that GT3 is associated with the incorporation of a novel sulfonated peptidyl-amido sugar moiety whose structure is reported in our accompanying paper (Bouché, L., Panico, M., Hitchen, P., Binet, D., Sastre, F., Faulds-Pain, A., Valiente, E., Vinogradov, E., Aubry, A., Fulton, K., Twine, S., Logan, S. …”
Publicado 2016
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13249“…The lanthanide-doped UCNPs bearing oleate ligands were first exchanged by citrates to generate polyanionic surfaces and then sequentially encapsulated with NH(2)-terminated poly(amido amine) (PAMAM) dendrimers (G4) and chlorine6 (Ce6) using a layer-by-layer (LBL) absorption strategy. …”
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13250“…A novel PNN ligand bearing an orthophenylene group and a primary amine was synthesized with the aid of a palladium-catalyzed amination and reacted with phosphonium dimers [–PR(2)CH(2)CH(OH)–](2)[Br](2) R = Et, iPr, Cy, Ph, xylyl, and o-Tol, and [Fe(OH(2))(6)](2+) to produce a new series of cis-β iron(ii) PNNP′ precatalysts cis-β-[Fe(Br)(CO)(PNNP′)]BPh(4) as a pair of diastereomers. …”
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13251por Zhang, Kaixi, Du, Yu, Si, Zhangyong, Liu, Yang, Turvey, Michelle E., Raju, Cheerlavancha, Keogh, Damien, Ruan, Lin, Jothy, Subramanion L., Reghu, Sheethal, Marimuthu, Kalisvar, De, Partha Pratim, Ng, Oon Tek, Mediavilla, José R., Kreiswirth, Barry N., Chi, Yonggui Robin, Ren, Jinghua, Tam, Kam C., Liu, Xue-Wei, Duan, Hongwei, Zhu, Yabin, Mu, Yuguang, Hammond, Paula T., Bazan, Guillermo C., Pethe, Kevin, Chan-Park, Mary B.“…Here, we report the synthesis of an enantiomeric block co-beta-peptide, poly(amido-D-glucose)-block-poly(beta-L-lysine), with high yield and purity by one-shot one-pot anionic-ring opening (co)polymerization. …”
Publicado 2019
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13252por Hutinet, Geoffrey, Kot, Witold, Cui, Liang, Hillebrand, Roman, Balamkundu, Seetharamsingh, Gnanakalai, Shanmugavel, Neelakandan, Ramesh, Carstens, Alexander B., Fa Lui, Chuan, Tremblay, Denise, Jacobs-Sera, Deborah, Sassanfar, Mandana, Lee, Yan-Jiun, Weigele, Peter, Moineau, Sylvain, Hatfull, Graham F., Dedon, Peter C., Hansen, Lars H., de Crécy-Lagard, Valérie“…In this study, we identify three additional 2′-deoxy-7-deazaguanine modifications, which are all intermediates of the same pathway, in viruses: 2′-deoxy-7-amido-7-deazaguanine (dADG), 2′-deoxy-7-cyano-7-deazaguanine (dPreQ(0)) and 2′-deoxy-7- aminomethyl-7-deazaguanine (dPreQ(1)). …”
Publicado 2019
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13253por Wendler, Felix, Sittig, Maria, Tom, Jessica C., Dietzek, Benjamin, Schacher, Felix H.“…Thereby, we distinguish between methacrylates (NMA, NOeMA), methacrylamides (NMAm, NOeMAm), vinyl naphthol (VN), and post‐polymerization modification based on [(1‐hydroxynaphthalen‐2‐amido)ethyl]amine (NOeMAm, NAmeMAm). These P(MEO(9)MA(x)‐co‐“N”(y)) copolymers typically feature a 4:1 MEO(9)MA to “N” ratio and molar masses in the range of 10 kg mol(−1). …”
Publicado 2020
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13254“…The selective lignin conversion into bio-based organic mono-aromatics is a major general challenge due to complex structure itself/additional macromolecule modifications, caused by the cleavage of the ether chemical bonds during the lignocellulosic biomass organosolv pulping in acidified aqueous ethanol. Herein, the acido-lysis of connected benzyl phenyl (BPE), being a representative model compound with α-O-4 linkage, was investigated in methanol, EtOH and 75 vol% EtOH/water mixture solutions, progressing each time with protonating sulfuric acid. …”
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13255por Ye, Yongheng, Zhang, Lingli, Dai, Yuhu, Wang, Zhi, Li, Cuie, Peng, Yue, Ma, Dong, He, Peiheng“…OBJECTIVE: This study aimed to develop aptamer-anchored hyperbranched poly(amido amine) (HPAA) for the systemic delivery of miRNA-133a-3p and to evaluate its therapeutic potential against bone metastasis of prostate cancer in vivo and in vitro. …”
Publicado 2020
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13256por Wang, Dianwen, Sun, Wenqiang, Yuan, Zhiyang, Sun, Qiang, Fan, Kai, Zhang, Chaopu, Yu, Sibin“…Among these loci, the novel locus qGL11 for grain length and thousand-grain weight was validated in a CSSL-derived segregating population and finely mapped to a 25-kb region that contains an IAA-amido synthetase gene OsGH3.13, This gene exhibited a significant expression difference in the young panicle between the near-isogenic lines that carry the contrasting Zhenshan 97 and Nipponbare alleles at qGL11. …”
Publicado 2021
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13257por Li, Jing, Ma, Xue-Jie, Wu, Xing, Si, Su-Jin, Li, Chong, Yang, Peng-Kun, Li, Guo-Xi, Liu, Xiao-Jun, Tian, Ya-Dong, Kang, Xiang-Tao“…To further investigate the expression of adiponectin and its receptors in follicles after in vitro incubation, and their role in the steroid synthesis of laying hens’ ovaries, we performed qRT-PCR and ELISA to detect the expressions of AdipoQ, AdipoR1, and AidpoR2, and determined the key genes involved in steroidogenesis and the secretion of estradiol (E2) and progesterone (P4) through the in vitro activation of adiponectin (AipoRon) and overexpression or knockdown of AdipoR1 and AdipoR2. …”
Publicado 2021
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13258por Méndez-Hernández, Hugo A., Quintana-Escobar, Ana O., Uc-Chuc, Miguel A., Loyola-Vargas, Víctor M.“…The GH3 family is one of the principal families of early response to auxin genes, exhibiting IAA-amido synthetase activity to maintain optimal levels of free auxin in the cell. …”
Publicado 2021
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13259“…Advancing this area of heterobimetallic chemistry, a new series of sodium ferrates is introduced incorporating the bulky arylsilyl amido ligand N(SiMe(3))(Dipp) (Dipp=2,6‐iPr(2)‐C(6)H(3)). …”
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13260por Kundisch, Almut, Hönning, Alexander, Mutze, Sven, Kreissl, Lutz, Spohn, Frederik, Lemcke, Johannes, Sitz, Maximilian, Sparenberg, Paul, Goelz, Leonie“…METHODS: In a retrospective multi-center cohort study, consecutive emergency non-contrast HCT scans were analyzed by a commercially available ICH detection software (AIDOC, Tel Aviv, Israel). Discrepancies between AI analysis and initial radiology report (RR) were reviewed by a blinded neuroradiologist to determine the number of additional ICHs detected and evaluate reasons leading to errors. …”
Publicado 2021
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