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  1. 16281
    “…Four new Glycosyl-NucleoLipid (GNL) analogs featuring either a single fluorocarbon or double hydrocarbon chains were synthesized in good yields from azido thymidine as starting material. Physicochemical studies (surface tension measurements, differential scanning calorimetry) indicate that hydroxybutanamide-based GNLs feature endothermic phase transition temperatures like the previously reported double chain glycerol-based GNLs. …”
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    Glycosyl-Nucleolipids as New Bioinspired Amphiphiles
  2. 16282
    “…The key intermediates are the corresponding multiply fluorinated glucosazide and galactosazide thioglycosides prepared from deoxyfluorinated 1,6-anhydro-2-azido-β-ᴅ-hexopyranose precursors by ring-opening reaction with phenyl trimethylsilyl sulfide. …”
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    Synthesis of multiply fluorinated N-acetyl-D-glucosamine and D-galactosamine analogs via the corresponding deoxyfluorinated glucosazide and galactosazide phenyl thioglycosides
  3. 16283
    “…We report here a novel reductive radical-polar crossover reaction that is a reductive radical-initiated 1,2-C migration of 2-azido allyl alcohols enabled by an azidyl group. …”
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    Reductive radical-initiated 1,2-C migration assisted by an azidyl group
  4. 16284
    “…We presented a facile and scalable route for the synthesis of di-azido sugars via one-pot double inversion of the mono-benzoyl sugars by TBAN(3) and studied the dependency pattern between solvent and protecting groups as well as the configuration of the neighboring and leaving groups. …”
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    Facile and Scalable Route to Access Rare Deoxy Amino Sugars for Nonulosonic Acid Aldolase Biosynthesis
  5. 16285
    “…By setting up a targeted azido-methylamino photo-reaction deep inside the active site of KDM4, engineered to carry p-azido phenylalanine, we reveal a novel “demethylome” that has escaped the traditional methods. …”
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    Activity Guided Azide-methyllysine Photo-trapping for Substrate Profiling of Lysine Demethylases
  6. 16286
    por Gräslund, A, Sahlin, M, Sjöberg, B M
    Publicado 1985
    “…The hypothetic role of the tyrosyl free radical in the enzymatic reaction is not yet elucidated, except in the reaction with the inhibiting substrate analogue 2'-azido-CDP. In this case, the normal tyrosyl radical is destroyed with concomitant appearance of a 2'-azido-CDP-localized radical intermediate. …”
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    The tyrosyl free radical in ribonucleotide reductase.
  7. 16287
    “…A very useful strategy is also the “switching on” of SMM behavior through replacement of bridging hydroxide groups by end-on azido or isocyanato ligands in clusters. Selected examples will be mentioned and critically discussed. …”
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    Coordination Clusters of 3d-Metals That Behave as Single-Molecule Magnets (SMMs): Synthetic Routes and Strategies
  8. 16288
    por Kim, Minwoo, Ma, Eunsook
    Publicado 2010
    “…2-Chloro-, 2-bromo- and 2-azido-1,4,6-androstatriene-3,17-diones were synthesized from 1α,2α-epoxy-4,6-androstadiene-3,17-dione (2) using HCl, HBr and NaN(3), respectively. …”
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    Synthesis of 2- and 7- Substituted C(19) Steroids Having a 1,4,6-Triene or 1,4-Diene Structure and Their Cytotoxic Effects on T47D and MDA-MB231 Breast Cancer Cells
  9. 16289
    “…Sixty male Sprague-Dawley rats were randomly divided into 6 groups including control (C), alcohol (M), alcohol + Golden Bifido (T), alcohol + glutamine (G), alcohol + Medilac-S(®) (N) and alcohol + Golden Bifido + glutamine (L). …”
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    Probiotic and glutamine treatments attenuate alcoholic liver disease in a rat model
  10. 16290
    “…Objective: ´Three formulas and three medicines,’ namely, Jinhua Qinggan Granule, Lianhua Qingwen Capsule, Xuebijing Injection, Qingfei Paidu Decoction, HuaShi BaiDu Formula, and XuanFei BaiDu Granule, were proven to be effective for coronavirus disease 2019 (COVID-19) treatment. …”
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    Network pharmacology for the identification of phytochemicals in traditional Chinese medicine for COVID-19 that may regulate interleukin-6
  11. 16291
    “…BACKGROUND: To evaluate the evidence behind claims that Chinese Herbal Medicine, specifically “three medicines and three formulations” (3M3F, comprising Jinhua Qinggan, Lianhua Qingwen, Xuebijing, Qingfei Paidu, Huashi Baidu, and Xuanfei Baidu), is an effective treatment for COVID‐19. …”
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    Chinese herbal medicine (“3 medicines and 3 formulations”) for COVID‐19: rapid systematic review and meta‐analysis
  12. 16292
    “…In the guidelines on fighting against COVID-19, the National Health Commission of the People's Republic of China has recommended certain TCM formulas, namely Jinhua Qinggan granule (JHQGG), Lianhua Qingwen granule (LHQWG), Qingfei Paidu decoction (QFPDD), Xuanfei Baidu granule (XFBD), Xuebijing injection (XBJ), and Huashi Baidu granule (HSBD) for treating COVID-19 infected individuals. …”
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    Therapeutic mechanisms and impact of traditional Chinese medicine on COVID-19 and other influenza diseases
  13. 16293
    por He, Xiaohua, Wu, Jianxiang, Gao, Chunyan
    Publicado 2020
    “…The chloro groups in PCELG block were transformed into azido groups via azide reactions, and the alkyne-terminated MPEG was grafted to the polypeptide block to afford the final product PAzoMA-b-poly((l-glutamate)-graft-methoxy poly(ethylene glycol)) (PAzoMA-b-(PELG-g-MPEG)) by click reaction. …”
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    Novel amphiphilic graft block azobenzene-containing copolymer with polypeptide block: synthesis, self-assembly and photo-responsive behavior
  14. 16294
    “…These dendrons were reacted with gold nanoparticles stabilized with a combination of a dodecanethiol and 11-azidoundecane-1-thiol. The azido group of the last compound allowed the functionalization of the nanoparticles with the six polybenzylic dendrons by 1,3-dipolar cycloaddition between their alkynyl groups and the terminal azido groups of the thiols. …”
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    Gold Nanoparticles Modification with Liquid Crystalline Polybenzylic Dendrons via 1,3-Dipolar Cycloaddition
  15. 16295
    “…Glycopolymers with mannose units were readily prepared by click chemistry of an azido mannopyranoside derivative and a poly(propargyl acrylate-co-N-vinyl pyrrolidone). …”
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    New amphiphilic glycopolymers by click functionalization of random copolymers – application to the colloidal stabilisation of polymer nanoparticles and their interaction with concanavalin A lectin
  16. 16296
    “…We describe the calixarene-cyclodextrin-coupling via click reaction starting from 5,11,17,23-tetra-tert-butyl-25,27-dipropargylether-26,28-hydroxy-calix[4]arene (calix[4]arene-dipropargylether) (2) onto 6I-azido-6I-deoxycyclomaltoheptaose (3) under microwave assisted conditions. …”
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    Calix[4]arene-click-cyclodextrin and supramolecular structures with watersoluble NIPAAM-copolymers bearing adamantyl units: “Rings on ring on chain”
  17. 16297
    por Okoth, Ronald, Basu, Amit
    Publicado 2013
    “…Post-polymerization modification of the polymer was accomplished by amidation with an azido-amine linker followed by Cu(I)-catalyzed azide–alkyne cycloaddition with propargyl sugars. …”
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    End-labeled amino terminated monotelechelic glycopolymers generated by ROMP and Cu(I)-catalyzed azide–alkyne cycloaddition
  18. 16298
    “…The analogues were prepared using a de novo asymmetric synthetic approach, which featured Pd-π-allylic catalyzed glycosylation for the introduction of a C4″-azido group. Surprisingly replacement of the C4″-acetate with a C4″-amide resulted in analogues that were no longer specific for RSK in cell-based assays.…”
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    De Novo Synthesis and Biological Evaluation of C6″-Substituted C4″-Amide Analogues of SL0101
  19. 16299
    “…A novel series of 2’-oxa-3’-aza-4’a-carbanucleosides, featured with a triazole linker at the 5’-position, has been developed by exploiting a click chemistry reaction of 5’-azido-2’-oxa-3’-aza-4’a-carbanucleosides with substituted alkynes. …”
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    C-5’-Triazolyl-2’-oxa-3’-aza-4’a-carbanucleosides: Synthesis and biological evaluation
  20. 16300
    “…Synthesis of azido(trimethylsilyl)acetylene (6) was performed by treating the iodonium salt 5 with highly soluble hexadecyltributylphosphonium azide (QN(3)) at −40 °C. …”
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    Synthesis, Characterization and Reactions of (Azidoethynyl)trimethylsilane
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