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  1. 16641
    “…Here, we demonstrate that a key component of HAART, 3ꞌ-azido-3ꞌ-deoxythymidine (AZT), particularly, its active metabolite AZT-triphosphate (AZT-TP), caused mitochondrial dysfunction, leading to induction of cell death in H9c2 cells derived from rat embryonic myoblasts, which serve as a model for cardiomyopathy. …”
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    Azidothymidine-triphosphate impairs mitochondrial dynamics by disrupting the quality control system
  2. 16642
    “…Combination of site-specific incorporation of a clickable p-azido-L-phenylalanine to Uox and strain-promoted azide-alkyne cycloaddition allowed the conjugation of fatty acid (palmitic acid analog) to Uox with the HSA binding capacity and retained enzyme activity. …”
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    Generation of therapeutic protein variants with the human serum albumin binding capacity via site-specific fatty acid conjugation
  3. 16643
    “…They were used to react with azido-functionalized polystyrene (PS) via Huisgen [3 + 2] cycloaddition ‘click’ chemistry to form two fullerene polymers: one with C(60) tethered to the end of a PS chain (C(60)-1PS) and the other with C(60) tethered at the junction point of two PS chains of identical molecular weight (C(60)-2PS). …”
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    Convenient syntheses of fullerynes for ‘clicking’ into fullerene polymers
  4. 16644
    “…Neste estudo, relatamos dois casos de trombose induzida pelo calor endovenoso que teriam indicação de heparina de baixo peso molecular até a resolução do quadro. Porém, optou-se pelo uso da rivaroxabana (15 mg de 12 em 12h), com resolução completa do trombo em 4 semanas (caso 1) e em 7 dias (caso 2). …”
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    Trombose induzida pelo calor endovenoso: relato de dois casos tratados com rivaroxabana e revisão da literatura
  5. 16645
    “…Cellular evaluation of these agents led to the discovery of an azido-ester that is metabolized to its cognate acyl-coenzyme A (CoA) and affords robust protein labeling profiles. …”
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    Bioorthogonal pro-metabolites for profiling short chain fatty acylation
  6. 16646
    “…Photo-reactive poly(vinyl alcohol) (PRPVA) was synthesized by introduction of phenyl azido groups into poly(vinyl alcohol) (PVA) and applied for surface modification. …”
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    Synthesis of photo-reactive poly (vinyl alcohol) and construction of scaffold-free cartilage like pellets in vitro
  7. 16647
    “…In this study, the transcriptomic data between an alkaline-tolerant (WD20342) and an alkaline-sensitive (Caidao) rice cultivar were compared under alkaline stress conditions. …”
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    Transcriptome analysis of two contrasting rice cultivars during alkaline stress
  8. 16648
    “…The synthetic strategy involved grafting of a phenylacetylene structure onto the carbon fiber surface, onto which O‐acylated 6‐azido‐6‐deoxycellulose and a number of aromatic azides could be covalently attached. …”
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    Interphase Engineering of a Cellulose‐Based Carbon Fiber Reinforced Composite by Applying Click Chemistry
  9. 16649
    “…The mol­ecule of the title compound, C(16)H(17)N(5)O(3), is build up from two fused six-membered rings linked to a 1,2,3-triazole ring, which is attached to an ethyl azido-acetate group. The di­hydro­qinoxalinone portion is planar to within 0.0512 (12) Å and is oriented at a dihedral angle of 87.83 (5)° with respect to the pendant triazole ring. …”
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    Crystal structure and Hirshfeld surface analysis of ethyl 2-{4-[(3-methyl-2-oxo-1,2-di­hydro­quinoxalin-1-yl)meth­yl]-1H-1,2,3-triazol-1-yl}acetate
  10. 16650
    “…For the introduction of the azido group the 5′-position of the nucleosides and a propargyl ether functional group on the 3-hydroxy group of 13α-estrone were chosen. …”
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    Synthesis and Biological Evaluation of Triazolyl 13α-Estrone–Nucleoside Bioconjugates
  11. 16651
    “…We collected combined search query data for the US and the UK from Google Trends, and for China from Baidu Index. A multivariate seasonal autoregressive integrated moving average model was developed to track influenza epidemics using Australian influenza and local search data. …”
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    Predicting seasonal influenza epidemics using cross-hemisphere influenza surveillance data and local internet query data
  12. 16652
    “…To overcome some of these limitations, we proposed an unnatural amino acid aided caging–uncaging strategy for controlling the transduction capability of a viral vector. …”
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    Generation of a caged lentiviral vector through an unnatural amino acid for photo-switchable transduction
  13. 16653
    “…The method involves covalent linking of a target protein to a unique molecule counting oligonucleotide at a 1:1 conjugation ratio based on an azido–cycloalkyne click reaction. The sensitivity of the HaloTag-based barcoding was remarkably higher than that of a conventional luciferase assay. …”
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    HaloTag-based conjugation of proteins to barcoding-oligonucleotides
  14. 16654
    por Kerner, Lukáš, Kosma, Paul
    Publicado 2020
    “…The ensuing selective monodemethylation and hydrogenolysis of the benzyl groups and reduction of the 4-azido group gave the α-ʟ-anomeric arabino- and ribo-configured methyl phosphonate esters. …”
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    Synthesis of C-glycosyl phosphonate derivatives of 4-amino-4-deoxy-α-ʟ-arabinose
  15. 16655
    “…METHODS: Using Internet search query volumes in Baidu (2017), the largest internet search engine in China, we constructed a prefectural panel data (278 prefectures, 52 weeks) and employed dynamic panel GMM system estimation to analyze the relationship between weekly concentration of PM2.5 (Mean = 87 μg·m(− 3)) and the index of suicidal ideation (Mean = 49.9). …”
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    The association between PM2.5 exposure and suicidal ideation: a prefectural panel study
  16. 16656
    “…Risk values ranged from 8.73 (Trinidad) to 1.57 (The Bahamas, Turks and Caicos Islands). All four countries that have documented occurrences of laboratory confirmed rabid bats were ranked highest (Trinidad and Tobago, Grenada, Cuba, Dominican Republic), as well as Haiti. …”
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    Risk Modeling of Bat Rabies in the Caribbean Islands
  17. 16657
    por Li, Chun, He, Jianhua, Duan, Xingwu
    Publicado 2020
    “…Based on the search query from Baidu search engine, three migration attention indexes (MAIs) are constructed to capture public migration attention in cyber space. …”
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    The Relationship Exploration between Public Migration Attention and Population Migration from a Perspective of Search Query
  18. 16658
    “…The title compound, C(19)H(17)ClN(4)O(2), was obtained via a two-step synthesis involving the enol-mediated click Dimroth reaction of 4-azido­anisole with methyl 3-cyclo­propyl-3-oxo­propano­ate leading to the 5-cyclo­propyl-1-(4-meth­oxy­phen­yl)-1H-1,2,3-triazole-4-carb­oxy­lic acid and subsequent acid amidation with 4-chloro­aniline by 1,1′-carbonyl­diimidazole (CDI). …”
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    Synthesis, crystal structure and Hirshfeld surface analysis of N-(4-chloro­phen­yl)-5-cyclo­propyl-1-(4-meth­oxy­phen­yl)-1H-1,2,3-triazole-4-carboxamide
  19. 16659
    “…Using the same molecular insight, we selected the active triphosphate forms of three other anti-viral agents, Alovudine, AZT (an FDA approved HIV/AIDS drug) and Tenofovir alafenamide (TAF, an FDA approved drug for HIV and hepatitis B) for evaluation as inhibitors of SARS-CoV-2 RdRp. …”
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    Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase
  20. 16660
    “…Relevant reference lists, Baidu Scholar and grey literature will also be checked. …”
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    Guipi decoction for insomnia: Systematic review and meta-analysis
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