Mostrando 481 - 500 Resultados de 1,734 Para Buscar 'l2tpd~', tiempo de consulta: 2.01s Limitar resultados
  1. 481
    “…Using a viral-mediated molecular replacement strategy in rat hippocampal slices, we found that AKAP is required for NMDA receptor-dependent LTD solely due to its interaction with calcineurin.…”
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  2. 482
  3. 483
  4. 484
  5. 485
    por Takkala, Petri, Woodin, Melanie A.
    Publicado 2013
    “…Disinhibition-mediated long-term potentiation (LTP) in the CA1 region of the hippocampus involves GABAergic synaptic plasticity at feedforward inhibitory inputs, resulting in the reduced shunting of glutamatergic excitatory currents. …”
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  6. 486
    “…In corticostriatal synapses, LTD (long-term depression) and LTP (long-term potentiation) are modulated by the activation of DA (dopamine) receptors, with LTD being the most common type of long-term plasticity induced using the standard stimulation protocols. …”
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  7. 487
  8. 488
    “…Here, we report that CCNY negatively regulates long-term potentiation (LTP) of synaptic strength through inhibition of AMPA receptor trafficking. …”
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  9. 489
    “…HFS applied 30 min after NE washout induced long-lasting (>4 h) LTP, which was significantly extended in duration relative to HFS alone. …”
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  10. 490
    “…Moreover, a predominant binding of PARP1 to single-strand DNA breaks, occluding its Erk binding sites, suppressed IEG expression and prevented the generation of LTP. These findings outline a PARP1-dependent mechanism required for LTP generation, which may be implicated in long-term memory acquisition and in its deterioration in senescence.…”
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  11. 491
    “…Synapse-specificity of LTP ensures that no interference arises from inputs irrelevant to the memory to be encoded. …”
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  12. 492
    “…Long-term potentiation (LTP) of excitatory synaptic transmission has long been considered a cellular correlate for learning and memory1,2. …”
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  13. 493
    “…Long-term depression (LTD) of parallel fibre/Purkinje cell synapses has been the favoured explanation for cerebellar motor learning such as classical eyeblink conditioning. …”
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  14. 494
    “…Acute application of stearated ht31, a membrane-permeant inhibitor of AKAPs, either during β-AR activation 30 min prior to LTP induction or during LTP induction, attenuated the persistence of LTP. …”
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  15. 495
  16. 496
    “…Here, we show that NMDA-induced long-term depression of synaptic transmission (NMDA-LTD) is accompanied by downregulation of PSD-95 protein levels. …”
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  17. 497
    “…Based on field potential recordings, we show that Nbea(+/−) mice display enhanced LTP of the granule cell population spike, but no differences in basal synaptic transmission, synapse numbers, short-term plasticity, or network inhibition. …”
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  18. 498
    “…We demonstrate further that the optogenetic induction of such LTP in vivo facilitates, while optogenetic long-term depression (LTD) diminishes, the behavioral effect of aggression training, implying a causal role for potentiation at AHiPM→VMHvl(Esr1) synapses in mediating the effect of this training. …”
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  19. 499
  20. 500
    “…Dendritic spines, small protrusions of the dendrites, enlarge upon LTP induction, linking morphological and functional properties. …”
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