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581por Liakath-Ali, Kif, Polepalli, Jai S., Lee, Sung-Jin, Cloutier, Jean-Francois, Südhof, Thomas C.“…Five decades ago, long-term potentiation (LTP) of synaptic transmission was discovered at entorhinal cortex→dentate gyrus (EC→DG) synapses, but the molecular determinants of EC→DG LTP remain largely unknown. …”
Publicado 2022
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582por Trześniewska-Ofiara, Zuzanna, Mendrycka, Mariola, Cudo, Andrzej, Szmulik, Magdalena, Woźniak-Kosek, AgnieszkaEnlace del recurso
Publicado 2022
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586por Alexandre, Cristina M, Bubb, Kerry L, Schultz, Karla M, Lempe, Janne, Cuperus, Josh T, Queitsch, Christine“…We identified environmental conditions that reveal or mask the increased variation in ltp2 hypomorphs, and found that increased expression of its closest paralog LTP1 is necessary for ltp2 phenotypes. …”
Publicado 2023
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587por Indolfi, Cristiana, Dinardo, Giulio, Klain, Angela, Contieri, Marcella, Umano, Giuseppina Rosaria, Decimo, Fabio, Abbadessa, Salvatore, Vitulano, Carolina, Ciprandi, Giorgio, Miraglia del Giudice, Michele“…RESULTS: About 52% of the test population was sensitized to at least one LTP molecule. For all the LTPs analyzed, sensitization increased over time. …”
Publicado 2023
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588por Belardo, Carmela, Boccella, Serena, Perrone, Michela, Fusco, Antimo, Morace, Andrea Maria, Ricciardi, Federica, Bonsale, Roozbe, ELBini-Dhouib, Ines, Guida, Francesca, Luongo, Livio, Bagetta, Giacinto, Scuteri, Damiana, Maione, Sabatino“…Consistently, electrophysiological analysis showed LTP recovery in the DG of the hippocampus, while the Ach level and ChoA-T were normalized. …”
Publicado 2023
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589por Alegre-Zurano, Laia, Caceres-Rodriguez, Alba, Berbegal-Sáez, Paula, Lassalle, Olivier, Manzoni, Olivier, Valverde, Olga“…A single dose of cocaine abolishes endocannabinoid-mediated long-term depression (eCB-LTD) in the nucleus accumbens (NAc) within 24 h of administration. …”
Publicado 2023
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591“…Both the acute ex vivo application of METH to hippocampal slices and systemic administration of METH decreased LTP. Interestingly, the acute ex vivo application of METH at a concentration of 30 or 60 µM increased baseline synaptic transmission as well as decreased LTP. …”
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592por Li, Hongda, Zhong, Xiaofen, Chau, Kevin Fongching, Williams, Emily Cunningham, Chang, Qiang“…We generated knockin mice that lack NAIP of MeCP2, and show here the Mecp2 phospho-mutant mice perform better in hippocampus-dependent memory tests, present enhanced LTP at two synapses in the hippocampus, and show increased excitatory synaptogenesis. …”
Publicado 2011
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593por Stepan, Jens, Dine, Julien, Fenzl, Thomas, Polta, Stephanie A., von Wolff, Gregor, Wotjak, Carsten T., Eder, Matthias“…There exists substantial evidence that some forms of explicit learning in mammals require long-term potentiation (LTP) at hippocampal CA3-CA1 synapses. While CA1 LTP has been well characterized at the monosynaptic level, it still remains unclear how the afferent systems to the hippocampus can initiate formation of this neuroplastic phenomenon. …”
Publicado 2012
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594por Suárez, Luz M., Cid, Elena, Gal, Beatriz, Inostroza, Marion, Brotons-Mas, Jorge R., Gómez-Domínguez, Daniel, de la Prida, Liset Menéndez, Solís, José M.“…While kainic acid is a popular method to induce seizures and to potentially affect synaptic plasticity, it can also produce physiological-like oscillations and trigger some forms of long-term potentiation (LTP). Here, we examine whether induction of LTP is altered in hippocampal slices prepared from rats with different sensitivity to develop status epilepticus (SE) by systemic injection of kainic acid. …”
Publicado 2012
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595por Pai, Balagopal, Siripornmongcolchai, Taweeporn, Berentsen, Birgitte, Pakzad, Ashraf, Vieuille, Christel, Pallesen, Ståle, Pajak, Maciej, Simpson, T. Ian, Armstrong, J. Douglas, Wibrand, Karin, Bramham, Clive R.“…A major goal is to identify changes in miRNA expression underlying protein synthesis-dependent forms of synaptic plasticity such as long-term potentiation (LTP). Previous analyses focused on changes in miRNA levels in total lysate samples. …”
Publicado 2014
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596por Petrini, Enrica Maria, Ravasenga, Tiziana, Hausrat, Torben J., Iurilli, Giuliano, Olcese, Umberto, Racine, Victor, Sibarita, Jean-Baptiste, Jacob, Tija C., Moss, Stephen J., Benfenati, Fabio, Medini, Paolo, Kneussel, Matthias, Barberis, Andrea“…Postsynaptic long-term potentiation of inhibition (iLTP) can rely on increased GABA(A) receptors (GABA(A)Rs) at synapses by promoted exocytosis. …”
Publicado 2014
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597por Koprowski, Robert“…This article is a review of the book “Methods in Research and Development of Biomedical Devices” (ISBN: 9789814434997, 98USD/65GBP, 177 pages) edited by Kelvin K L Wong, Jiyuan Tu, Zhonghua Sun and Don W Dissanayake published by the World Scientific Publishing Co. Pte. Ltd. in 2013. The content of the book and its importance for biomedical engineering have been discussed in this invited review.…”
Publicado 2014
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598“…This hypothesis was based on preliminary experiments using electrical stimulation of the whiskers pad performed in alert mice showing that after a 8 Hz LTD-inducing protocol, the cerebellar LTD accompanied by a delayed response in the wild type (WT) mice is missing in Ube3a(m−/p+) mice and that the LTD induced in the barrel cortex following the same peripheral stimulation in wild mice is reversed into a LTP in the Ube3a(m−/p+) mice. …”
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599por Brachet, Anna, Norwood, Stephanie, Brouwers, Jos F., Palomer, Ernest, Helms, J. Bernd, Dotti, Carlos G., Esteban, José A.“…In this paper, we addressed the question of the role of cholesterol in synaptic changes during long-term potentiation (LTP). We found that N-methyl-d-aspartate–type glutamate receptor (NMDAR) activation during LTP induction leads to a rapid and sustained loss or redistribution of intracellular cholesterol in the neuron. …”
Publicado 2015
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600por Klöppel, Stefan, Lauer, Eliza, Peter, Jessica, Minkova, Lora, Nissen, Christoph, Normann, Claus, Reis, Janine, Mainberger, Florian, Bach, Michael, Lahr, Jacob“…LTP-like plasticity measured by visual evoked potentials (VEP) can be induced in the intact human brain by presenting checkerboard reversals. …”
Publicado 2015
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