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1141por Zhang, Xueying, Xu, Ying, Fu, Lulu, Li, Dandan, Dai, Xiaowei, Liu, Lianlian, Zhang, Jingshun, Zheng, Lianwen, Cui, Manhua“…The differential expression of Hmgn5, Nr5a2, Dll4, Entpd1, Fam50a, and Brms1 were further validated by quantitative reverse transcription polymerase chain reaction (qRT-PCR). …”
Publicado 2018
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1142Identification of Energy Metabolism Genes for the Prediction of Survival in Hepatocellular Carcinomapor Chen, Qinjunjie, Li, Fengwei, Gao, Yuzhen, Xu, Gaoran, Liang, Leilei, Xu, Jingchao“…The risk model showed that high ANLN, ENTPD2, TRIP13, PLAC8, and G6PD expression levels were associated with bad prognosis, and high expression of ADH1C was associated with a good prognosis. …”
Publicado 2020
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1143por Carter, Ben, Zenasni, Zohra, Moat, Stuart J, Hudson, Peter R, Russell, Ian T, McCaddon, AndrewEnlace del recurso
Publicado 2021
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1144por Zheng, Yanjun, Bian, Yuehong, Wu, Richao, Chen, Wei, Fu, Linlin, Li, Ping, Wang, Ying, Yang, Xiao, Zhao, Shigang, Shi, Yuhua“…Seven lncRNAs (NONHSAT101926.2, NONHSAT136825.2, NONHSAT227177.1, NONHSAT010538.2, NONHSAT191377.1, NONHSAT230904.1, ENST00000607307) and 3 mRNAs (EREG, ENTPD6, YAP1) were validated consistent with sequence profile. …”
Publicado 2021
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1145“…Yet, the ectoenzymes of the canonical and non-canonical adenosinergic pathway (ENTPD1 and CD38) are upregulated, suggesting that adenosine is produced by both active adenosinergic pathways. …”
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1146por Chen, Wuzhen, Li, Baizhou, Jia, Fang, Li, Jiaxin, Huang, Huanhuan, Ni, Chao, Xia, Wenjie“…PANX1 expression was also positively correlated with tumor-associated neutrophil (TAN) infiltration in breast cancer TME and TANs highly expressed ENTPD1 (CD39)/NT5E (CD73). Conclusions: This study suggests that high PANX1 expression is associated with high TAN infiltration and adenosine production to induce local immunosuppression in basal-like breast cancer TME.…”
Publicado 2022
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1147por Mondal, Tanmoy, Loffredo, Christopher A., Trnovec, Tomas, Palkovicova Murinova, Lubica, Noreen, Zarish, Nnanabu, Thomas, Conka, Kamil, Drobna, Beata, Ghosh, Somiranjan“…Maximum downregulation (in fold change) was observed in the ENTPD3 gene, and the minimum level of downregulation was in CYP2D6. …”
Publicado 2022
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1148por Nong, Shu-Xiong, Liang, Dong, Ma, Xiao, Luo, Cheng, Li, Long-Chang, Chen, Yu-Shan, Gui, Chun“…Biological enrichment analysis showed that the DEGs were associated with metabolic pathways, and vascular smooth muscle contraction and were mainly involved the MAPK signaling pathway, metabolic pathways, and the PI3K-Akt signaling pathway. The S100A8, ENTPD1, and MMP9 further screened were screened. …”
Publicado 2022
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1149por Liu, Meitong, Zhao, Yaning, Xiao, Zhuoyun, Zhou, Rongmiao, Chen, Xiaodong, Cui, Saijin, Cao, Shiru, Huang, Xi, Chen, Tianyu, Huo, Xiangran, Zhang, Guoqiang, Tian, Ziqiang, Wang, Na“…The expression of CD39 on CD8(+) T cells in the CK(+) region was higher in cancer tissue than in paracancerous tissue (p = 0.011), and high CD39-expressing CD8(+) T cells in the CK(+) region (HR, 2.587; p = 0.033) and high CD39-expressing CD8(+) T cells in the CK(−) region (HR, 3.090; p = 0.008) were independent risk factors for prognosis in ESCC patients; the expression of ENTPD1 was upregulated in ESCC tissues compared to normal tissues (adjusted p < 0.001; log(2) fold change = 1.99), and its expression was significantly positively correlated with the expression of PDCD1, CTLA4, and HAVCR2. …”
Publicado 2023
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1150“…We found that the ten candidate ICD genes (CALR, ENTPD1, FOXP3, HSP90AA1, IFNB1, IFNG, IL6, LY96, PIK3CA, and TLR4) could affect the prognosis of ccRCC (p < 0.05). …”
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1151por Komuro, Hiroyasu, Shinohara, Shuichi, Fukushima, Yasunori, Demachi-Okamura, Ayako, Muraoka, Daisuke, Masago, Katsuhiro, Matsui, Takuya, Sugita, Yusuke, Takahashi, Yusuke, Nishida, Reina, Takashima, Chieko, Ohki, Takashi, Shigematsu, Yoshiki, Watanabe, Fumiaki, Adachi, Katsutoshi, Fukuyama, Takashi, Hamana, Hiroshi, Kishi, Hiroyuki, Miura, Daiki, Tanaka, Yuki, Onoue, Kousuke, Onoguchi, Kazuhide, Yamashita, Yoshiko, Stratford, Richard, Clancy, Trevor, Yamaguchi, Rui, Kuroda, Hiroaki, Doi, Kiyoshi, Iwata, Hisashi, Matsushita, Hirokazu“…An exhausted T-cell (exhausted T (Tex)) cluster characterized by the expression of ENTPD1 (CD39), TOX, PDCD1 (PD1), HAVCR2 (TIM3) and other genes, and by T-cell oligoclonality, was identified. …”
Publicado 2023
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1152por Mallardo, Domenico, Fordellone, Mario, White, Andrew, Ottaviano, Margaret, Sparano, Francesca, Bailey, Michael, Facchini, Arianna Bianca, Ong, Sufey, Maiolino, Piera, Caracò, Corrado, Church, Sarah, Cavalcanti, Ernesta, Warren, Sarah, Budillon, Alfredo, Cesano, Alessandra, Simeone, Ester, Chiodini, Paolo, Ascierto, Paolo Antonio“…The genes positively associated with NLR (CD39 (ENTPD1), PTEN, MYD88, MMP9 and LDH) are involved in processes of immunosuppression, inflammation and tumor-promoting activity. …”
Publicado 2023
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1153por Pizzini, Silvia, Bisognin, Andrea, Mandruzzato, Susanna, Biasiolo, Marta, Facciolli, Arianna, Perilli, Lisa, Rossi, Elisabetta, Esposito, Giovanni, Rugge, Massimo, Pilati, Pierluigi, Mocellin, Simone, Nitti, Donato, Bortoluzzi, Stefania, Zanovello, Paola“…The suppressor activity of miR-182 on ENTPD5 gene was identified for the first time and confirmed in an independent set of samples. …”
Publicado 2013
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1154por Melchiotti, Rossella, Puan, Kia Joo, Andiappan, Anand Kumar, Poh, Tuang Yeow, Starke, Mireille, Zhuang, Li, Petsch, Kerstin, Lai, Tuck Siong, Chew, Fook Tim, Larbi, Anis, Wang, De Yun, Poidinger, Michael, Rotzschke, Olaf“…Regulatory T cells (Treg) can suppress inflammation by hydrolysing this molecule via ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), also termed as CD39. Multiple studies have reported differences in CD39(+) Treg percentages in diseases such as multiple sclerosis, Hepatitis B and HIV-1. …”
Publicado 2014
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1155por Cai, Xiao-Yan, Ni, Xiao-Chun, Yi, Yong, He, Hong-Wei, Wang, Jia-Xing, Fu, Yi-Peng, Sun, Jian, Zhou, Jian, Cheng, Yun-Feng, Jin, Jian-Jun, Fan, Jia, Qiu, Shuang-Jian“…Nucleoside triphosphate diphosphohydrolase-1 (ENTPD1/CD39) is the rate-limiting enzyme in a cascade leading to the generation of immunosuppressive adenosine and plays an important role in tumor progression. …”
Publicado 2016
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1156por Yang, Rui, Elsaadi, Samah, Misund, Kristine, Abdollahi, Pegah, Vandsemb, Esten Nymoen, Moen, Siv Helen, Kusnierczyk, Anna, Slupphaug, Geir, Standal, Therese, Waage, Anders, Slørdahl, Tobias S, Rø, Torstein Baade, Rustad, Even, Sundan, Anders, Hay, Carl, Cooper, Zachary, Schuller, Alwin G, Woessner, Richard, Borodovsky, Alexandra, Menu, Eline, Børset, Magne, Sponaas, Anne Marit“…METHODS: Expression of CD39 and CD73 on BM cells from patients and T-cell proliferation were determined by flow cytometry and adenosine production by Liquid chromatograpy-mass spectrometry (HPCL/MS). ENTPD1 (CD39) mRNA expression was determined on myeloma cells from patients enrolled in the publicly available CoMMpass study. …”
Publicado 2020
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1157por Lei, Dan, Hong, Tao, Li, Longxue, Chen, Lai, Luo, Xiaoquan, Wu, Qinghua, Liu, ZhiyongEnlace del recurso
Publicado 2021
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1158por Karlsson, Ida K., Ericsson, Malin, Wang, Yunzhang, Jylhävä, Juulia, Hägg, Sara, Dahl Aslan, Anna K., Reynolds, Chandra A., Pedersen, Nancy L.“…We identified six significant associations between DNA methylation and level of cognitive abilities at age 65: cg18064256 (PPP1R13L) with processing speed and spatial ability; cg04549090 (NRXN3) with spatial ability; cg09988380 (POGZ), cg25651129 (-), and cg08011941 (ENTPD8) with working memory. The genes are involved in neuroinflammation, neuropsychiatric disorders, and ATP metabolism. …”
Publicado 2021
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1159por Elghzaly, Ashraf A., Sun, Celi, Looger, Loren L., Hirose, Misa, Salama, Mohamed, Khalil, Noha M., Behiry, Mervat Essam, Hegazy, Mohamed Tharwat, Hussein, Mohamed Ahmed, Salem, Mohamad Nabil, Eltoraby, Ehab, Tawhid, Ziyad, Alwasefy, Mona, Allam, Walaa, El-Shiekh, Iman, Elserafy, Menattallah, Abdelnaser, Anwar, Hashish, Sara, Shebl, Nourhan, Shahba, Abeer Abdelmonem, Elgirby, Amira, Hassab, Amina, Refay, Khalida, El-Touchy, Hanan Mohamed, Youssef, Ali, Shabacy, Fatma, Hashim, Abdelkader Ahmed, Abdelzaher, Asmaa, Alshebini, Emad, Fayez, Dalia, El-Bakry, Samah A., Elzohri, Mona H., Abdelsalam, Eman Nagiub, El-Khamisy, Sherif F., Ibrahim, Saleh, Ragab, Gaafar, Nath, Swapan K.“…SNPs correlated (r (2) > 0.8) with lead SNPs from four suggestive loci (ARMC9, DIAPH3, IFLDT1, and ENTPD3) were associated with differential gene expression (3.5 × 10(−95) < p < 1.0 × 10(−2)) across diverse tissues. …”
Publicado 2022
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1160por Li, Houqiang, Sha, Xinyu, Wang, Wenmiao, Huang, Zhanghao, Zhang, Peng, Liu, Lei, Wang, Silin, Zhou, Youlang, He, Shuai, Shi, Jiahai“…Differential analysis of ICIs revealed CD276, ICOS, PDCD1LG2, CD27, TNFRSF18, TNFSF9, ENTPD1, and NT5E to be expressed differently in the low- and high-risk groups. …”
Publicado 2023
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