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26781Exploring the Molecular Mechanisms of Pterygium by Constructing lncRNA–miRNA–mRNA Regulatory Network“…A competitive endogenous RNA (ceRNA) network was constructed to elucidate the molecular mechanisms in pterygium. …”
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26782por Guo, Chao, Gao, Ya-yue, Ju, Qian-qian, Zhang, Chun-xia, Gong, Ming, Li, Zhen-ling“…Furthermore, the network of ceRNA was established with 6 miRNAs and 122 mRNAs. …”
Publicado 2020
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26783por Zhang, Qi, Sun, Lin, Zhang, Qiuju, Zhang, Wei, Tian, Wei, Liu, Meina, Wang, Yupeng“…By integrating this network with the online tool‐based ceRNA network, an HCC‐specific ceRNA network was obtained, and lncRNA‐miRNA‐mRNA regulatory axes were extracted. …”
Publicado 2020
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26784“…In this study, we investigated whether the exosomal lncRNA H19 could act as a competing endogenous RNA (ceRNA) to potentiate osteochondral activity in chondrocytes. …”
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26785“…MicroRNAs linked with these DElncRNAs and DEmRNAs were predicted and a competitive endogenous RNA (ceRNA) network was built. A total of 53 DElncRNAs and 301 DEmRNAs were identified between control and PE samples. …”
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26786Identification of the canonical and noncanonical role of miR-143/145 in estrogen-deficient bone losspor Xu, Rongyao, Shen, Xin, Xie, Hanyu, Zhang, Hengguo, Liu, Dingshan, Chen, Xin, Fu, Yu, Zhang, Ping, Yang, Yi, Cheng, Jie, Jiang, Hongbing“…Methods: We examined the serum, salivary and bone samples from Pre- and Post-menopause women by paired analysis and confirmed canonical ceRNA role of MIR143HG and miR-143/145 complexes in cytoplasm and noncanonical role for SOX2 transcription in nucleus (FISH, qRT-PCR, immunostaining, Luciferase assays and ChIP). …”
Publicado 2021
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26787“…Differentially expressed mRNAs, miRNAs, and lncRNAs were identified between LUAD tissues and normal tissues. A ceRNA regulatory network was constructed on previous differentially expressed mRNAs, miRNAs, and lncRNAs. …”
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26788por Darbeheshti, Farzaneh, Zokaei, Elham, Mansoori, Yaser, Emadi Allahyari, Sima, Kamaliyan, Zeeba, Kadkhoda, Sepideh, Tavakkoly Bazzaz, Javad, Rezaei, Nima, Shakoori, Abbas“…The roles of circRNAs as the competing endogenous RNAs (ceRNAs) to sponge microRNAs (miRNAs) have also been indicated. …”
Publicado 2021
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26789“…The present review introduces two competing endogenous RNA (ceRNA) regulatory networks centered on miR-490-3p and miR-490-5p. …”
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26790“…Circular RNA (circRNA) and their associated competing endogenous RNA (ceRNA) network play critical roles in the pathogenesis of glioma. …”
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26791por Li, Xinsheng, Wang, Jingfan, Qian, Huiming, Wu, Yan, Zhang, Zhengyu, Hu, Zizhong, Xie, Ping“…Next, bioinformatics analyses including competitive endogenous RNA (ceRNA) network, protein–protein interaction network (PPI), and functional enrichment analyses were performed. …”
Publicado 2021
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26792por Peng, Yurui, Xu, Chenxin, Wen, Jun, Zhang, Yuanchuan, Wang, Meng, Liu, Xiaoxiao, Zhao, Kang, Wang, Zheng, Liu, Yanjun, Zhang, Tongtong“…After screening differentially expressed RNAs, we constructed a fatty acid metabolism-related competing endogenous RNA (ceRNA) network based on the miRTarBase, miRDB, TargetScan, and StarBase databases. …”
Publicado 2021
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26793por Bao, Jiapeng, Lin, Changjian, Zhou, Xing, Ma, Diana, Ge, Lujie, Xu, Kai, Moqbel, Safwat Adel Abdo, He, Yuzhe, Ma, Chiyuan, Ran, Jisheng, Wu, Lidong“…Competitive endogenous RNAs (ceRNAs), as a newly identified regulating mechanism, have been demonstrated to play a crucial role in various human diseases. …”
Publicado 2021
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26794“…Furthermore, a ceRNA regulatory pathway, namely lncRNA-AC010198.2/hsa-miR-34b-3p/STC2, was selected by RT-qPCR validation and literature searching. …”
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26795por Singh, Mithilesh, Tripathi, Pranav, Singh, Smriti, Sachan, Manisha, Chander, Vishal, Sharma, Gaurav Kumar, De, Ujjwal Kumar, Kota, Sathish, Putty, Kalyani, Singh, Raj Kumar, Nara, Seema“…Target binding of all ten aptamers was assessed by dot blot and enzyme-linked oligonucleotide assay (ELONA) which revealed that 5A, 6A, 9A, and 10A were superior binders. …”
Publicado 2021
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26796“…After survival analysis based on the expression of the RNAs in the ceRNA network, 8 lncRNAs, 4 miRNAs and 11 mRNAs that were significantly associated with OC patient survival (P<0.05) were obtained. …”
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26797por Chen, Jia, Chen, Yuhan, Du, Xue, Liu, Guojun, Fei, Xiaowei, Peng, Jian Ru, Zhang, Xing, Xiao, Fengjun, Wang, Xue, Yang, Xiao, Feng, Zhichun“…Through rigorous selection of the lncRNA/circRNA-based ceRNA network, we demonstrated that the hub genes reside in UC-MSC- and CB-MNC-infused networks directed to the function of cell adhesion, motor transportation (Cdk13, Lrrn2), immune homeostasis balance, and autophagy (Homer3, Prkcd) relatively. …”
Publicado 2021
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26798por Fan, Jiaxin, Chen, Mengying, Cao, Shuai, Yao, Qingling, Zhang, Xiaodong, Du, Shuang, Qu, Huiyang, Cheng, Yuxuan, Ma, Shuyin, Zhang, Meijuan, Huang, Yizhou, Zhang, Nan, Shi, Kaili, Zhan, Shuqin“…Of these genes, 4 DEFRGs were incorporated into the competitive endogenous RNA (ceRNA) network, including 78 lncRNA-miRNA and 16 miRNA-mRNA interactions. …”
Publicado 2022
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26799por Liu, Lanxiang, Wang, Haiyang, Chen, Xueyi, Zhang, Yangdong, Li, Wenxia, Rao, Xuechen, Liu, Yiyun, Zhao, Libo, Pu, Juncai, Gui, Siwen, Yang, Deyu, Fang, Liang, Xie, Peng“…Subsequently, according to the competitive endogenous RNAs (ceRNA) hypothesis and the biological functions of these intersected genes, two neurodevelopmental ceRNA sub-networks implicating in depression were identified, one including two lncRNAs (4930417H01Rik and AI480526), one miRNA (mmu-miR-883b-3p) and two mRNAs (Adcy1 and Nr4a2), and the other including six lncRNAs (5930412G12Rik, 6430628N08Rik, A530013C23Rik, A930007I19Rik, Gm15489, and Gm16251), one miRNA (mmu-miR-377-3p) and three mRNAs (Six4, Stx16, and Ube3a), and these molecules could be recognized as potential genetic and epigenetic biomarkers in microbial-associated depression. …”
Publicado 2022
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26800por Jiang, Lin, Zhang, Yingjing, Su, Pengfei, Ma, Zhiqiang, Ye, Xin, Kang, Weiming, Liu, Yuqin, Yu, Jianchun“…Competitive endogenous RNA (ceRNA) mechanisms were explored through luciferase assays and RNA immunoprecipitation (RIP) assays. …”
Publicado 2022
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