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26921por Deng, Ya-Jun, Li, Zhi, Wang, Bo, Li, Jie, Ma, Jun, Xue, Xiong, Tian, Xin, Liu, Quan-Cheng, Zhang, Ying, Yuan, Bin“…Then, we constructed NEAT1-hsa-miR-128-3p-IL17RA, and SNHG1-hsa-miR-128-3p-IL17RA ceRNA networks in addition to ERF-IL17RA, IRF8-IL17RA, POLR2A-IL17RA and ERG-IL17RA transcriptional networks. …”
Publicado 2023
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26922por Yang, Li, Zhou, Lin, Li, Fangyi, Chen, Xiaotong, Li, Ting, Zou, Zijun, Zhi, Yaowei, He, Zhijie“…Then, key genes were analyzed by functional enrichment, protein-protein interaction (PPI), transcription factor (TF)-gene and competing endogenous RNA (ceRNA) network analysis. Subsequently, key genes with diagnostic efficiency and prognostic value were identified by receiver operating characteristic (ROC) curves and survival analysis respectively. …”
Publicado 2023
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26923por Zhang, Zhi-Guo, Shi, Zhen-Duo, Dong, Jia-Jun, Chen, Yu-Ang, Cao, Ming-Yang, Li, Yun-Tian, Ma, Wei-Ming, Hao, Lin, Pang, Kun, Zhou, Jia-He, Zhang, Wen-Da, Dong, Yang, Han, Cong-Hui“…Competing endogenous RNA (ceRNA) network was also visualized using Cytoscape. …”
Publicado 2023
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26924por Niu, Jianfei, Guo, Wei, Lu, Aiyangzi, Han, Guanxiong, Wang, Guanqun, Peng, Bihui, Zhao, Jiping“…Among them, PTEN is involved in forming a ceRNA network containing 3 LncRNAs, 3 miRNAs and 3 mRNAs. …”
Publicado 2023
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26925por Xie, Lin, Yao, Zhihong, Zhang, Ya, Li, Dongqi, Hu, Fengdi, Liao, Yedan, Zhou, Ling, Zhou, Yonghong, Huang, Zeyong, He, Zewei, Han, Lei, Yang, Yihao, Yang, Zuozhang“…Then, the target DEmRNAs and DElncRNAs regulated by the same DEmiRNAs were searched and the OS tumorigenesis-related and OS pulmonary metastasis-related competing endogenous RNA (ceRNA) networks were constructed, respectively. Based on these ceRNA networks and Venn diagram analysis, we obtained 3 DEmiRNAs, 15 DElncRNAs, and 100 DEmRNAs, and eight target pairs including miR-223-5p/(CLSTN2, AC009951.1, LINC01705, AC090673.1), miR-378b/(ALX4, IGSF3, SULF1), and miR-323b-3p/TGFBR3 were involved in both tumorigenesis and pulmonary metastasis of OS. …”
Publicado 2018
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26926“…Finally, we used the Database for Annotation, Visualization and Integrated Discovery (DAVID) and KOBAS software and data from the Gene Expression Omnibus (GEO) database to analyze the possible competing endogenous RNA (ceRNA) network pattern as well as the co-expression network in liver cancer. …”
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26927por Li, Cheng-Yun, Zhang, Wen-Wen, Xiang, Ji-Lian, Wang, Xing-Hua, Wang, Jun-Ling, Li, Jin“…Based on these intersected lncRNAs, the present study constructed a competitive endogenous RNA (ceRNA) network of lncRNAs in ESCC. A total of 81 intersection lncRNAs were identified; 67 of these were included in the ceRNA network. …”
Publicado 2019
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26928por Chen, Zili, Ma, Yifei, Pan, Yaozhen, Zuo, Shi, Zhu, Haitao, Yu, Chao, Zhu, Changhao, Sun, Chengyi“…Furthermore, bioinformatics and luciferase reporter assay identified that RP5-833A20.1 functioned as a competing endogenous RNA (ceRNA) for miR-18a-5p in HCC. CONCLUSION: In this study, we found that RP5‑833A20.1 was downregulated in HCC tissues. …”
Publicado 2019
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26929“…The present findings provide a novel perspective for improved understanding of the lncRNA-associated ceRNA network and may facilitate the development of novel targeted therapeutics in colon cancer.…”
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26930por Zhao, Jun, Su, Yu, Jiao, Jianfei, Wang, Zhengchun, Fang, Xiangchun, He, Xuefeng, Zhang, Xiaofeng, Liu, Zhao, Xu, Xilin“…A competing endogenous RNA network (ceRNA) based on the screened mRNAs, lncRNAs, and related miRNAs was constructed to reveal presumptive biomarkers further. …”
Publicado 2020
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26931“…LPP-AS2 was found to function as a ceRNA to regulate EGFR expression by sponging miR-7-5p in glioma cells. …”
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26932por Du, Chuang, Wang, Yan, Zhang, Yingying, Zhang, Jianhua, Zhang, Linfeng, Li, Jingruo“…Recent studies report that long noncoding RNAs (lncRNAs)-mediated competing endogenous RNAs (ceRNA) play an important role in tumorigenesis and drug resistance of TNBC. …”
Publicado 2020
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26933por Zeng, Yuyang, He, Tao, Liu, Juejun, Li, Zongyuan, Xie, Feijia, Chen, Changzheng, Xing, Yiqiao“…Subsequently, we identified the differentially methylated genes, differentially expressed miRNAs (DEMs) and lncRNAs (DELs), and intersected them with key genes to analyze possible targets of the underlying epigenetic regulatory mechanisms. Finally, the ceRNA network of lncRNAs-miRNAs-mRNAs was constructed using Cytoscape. …”
Publicado 2020
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26934por Limb, Christopher, Liu, Daniel S. K., Veno, Morten T., Rees, Eleanor, Krell, Jonathan, Bagwan, Izhar N., Giovannetti, Elisa, Pandha, Hardev, Strobel, Oliver, Rockall, Timothy A., Frampton, Adam E.“…Therefore, the aim of this systematic review was to describe the roles of circRNAs in PDAC and BTC, their potential as biomarkers, and their function in the wider ceRNA network in regulating microRNAs and the transcriptome. …”
Publicado 2020
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26935por Gong, Peng-Ju, Shao, You-Cheng, Huang, Si-Rui, Zeng, Yi-Fan, Yuan, Xiao-Ning, Xu, Jing-Jing, Yin, Wei-Nan, Wei, Lei, Zhang, Jing-Wei“…Predictions based on the LINC00899/PSMG3-AS1/PAXIP1-AS1- hsa-miR-210-3p-CPEB2 and SNHG16- hsa-miR-190b-BCL11A ceRNA regulation networks indicated that the two genes might act as tumor suppressor and oncogene, respectively. …”
Publicado 2020
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26936por Cao, Fang, Guo, Yu, Zhang, Qiang, Fan, Yinchun, Liu, Qian, Song, Jiancheng, Zhong, Hua, Yao, Shengtao“…After integration of DEmiRNA–DEmRNA and DElncRNA–DEmiRNA relationships, we constructed a ceRNA network, composed of 71 DEmRNAs, 17 DEmiRNAs, and 12 DElncRNAs. …”
Publicado 2020
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26937por Zhu, Jie, Zhou, Yong, Zhu, Shanshan, Li, Fei, Xu, Jiajia, Zhang, Liming, Shu, Hairong“…The circRNA_102049/miR-455-3p/CD80 axis was identified by the ceRNA network and hub genes. In vitro and in vivo experiments were performed to evaluate the functions of circRNA_102049. …”
Publicado 2021
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26938por Chen, Yanfang, Chen, Zheng, Mo, Jian, Pang, Mao, Chen, Zihao, Feng, Feng, Xie, Peigen, Yang, Bu“…The co-expression and competing endogenous RNAs (ceRNAs) networks were constructed to identify hub lncRNAs. …”
Publicado 2021
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26939“…BACKGROUND: Targeting the long non-coding RNAs (LncRNAs)-microRNAs (miRNAs)-mRNA competing endogenous RNA (ceRNA) networks has been proved as an effective strategy to treat multiple cancers, including oral squamous cell carcinoma (OSCC). …”
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26940por Lee, Woo Joo, Shin, Chang Hoon, Ji, Haein, Jeong, Seong Dong, Park, Mi-So, Won, Hong-Hee, Pandey, Poonam R., Tsitsipatis, Dimitrios, Gorospe, Myriam, Kim, Hyeon Ho“…Since LINC00263 was mainly localized in the cytosol and highly enriched in Argonaute 2-immunoprecipitation (Ago2-IP), we hypothesized that LINC00263 acts as a competitive endogenous RNA (ceRNA), and thus sought to identify LINC00263-associated microRNAs. …”
Publicado 2021
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