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27061por Wang, Hui, Zhong, Jincheng, Wang, Jikun, Chai, Zhixin, Zhang, Chengfu, Xin, Jinwei, Wang, Jiabo, Cai, Xin, Wu, Zhijuan, Ji, Qiumei“…A competing endogenous RNA (ceRNA) network was constructed by integrating the competing relationships among co-differentially expressed mRNAs, miRNAs, lncRNAs and circRNAs. …”
Publicado 2021
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27062por Jia, Guizhi, Wang, Yan, Lin, Chengjie, Lai, Shihui, Dai, Hongliang, Wang, Zhiqian, Dai, Luo, Su, Huizhao, Song, Yanjie, Zhang, Naiwen, Feng, Yukuan, Tang, Bo“…RNA immunoprecipitation (RIP) and RNA pull down were applied to identify the molecular sponge role of LNCAROD for modulation of miR-145-5p via the competing endogenous RNA (ceRNA) mechanism, as well as the interaction between LNCAROD and serine-and arginine-rich splicing factor 3 (SRSF3). …”
Publicado 2021
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27063por Dong, Yang, Ma, Wei-ming, Yang, Wen, Hao, Lin, Zhang, Shao-qi, Fang, Kun, Hu, Chun-hui, Zhang, Qian-jin, Shi, Zhen-duo, Zhang, Wen-da, Fan, Tao, Xia, Tian, Han, Cong-hui“…FN1 was potentially regulated by miR-429, miR-216b and miR-217, and constructed a bridge to C3 and C3AR1 in the ceRNA network, indicating a critical position of FN1. …”
Publicado 2021
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27064“…BACKGROUND: The underlying circular RNAs (circRNAs)-related competitive endogenous RNA (ceRNA) mechanisms of pathogenesis and prognosis in non-small cell lung cancer (NSCLC) remain unclear. …”
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27065por Liu, Ying, Dong, Ying, Dong, Zhaojie, Song, Jiawei, Zhang, Zhenzhou, Liang, Lirong, Liu, Xiaoyan, Sun, Lanlan, Li, Xueting, Zhang, Miwen, Chen, Yihang, Miao, Ran, Zhong, Jiuchang“…Based on theirs high stability with a closed loop structure, circRNAs function as a sponge and bind specific miRNAs to exert inhibitory effects in heart and vasculature, thereby regulating their target gene and protein expression, via competitive endogenous RNA (ceRNA) mechanism. However, the exact roles and underlying mechanisms of circRNAs in hypertension and related cardiovascular diseases remain largely unknown. …”
Publicado 2021
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27066por Rojano, Elena, Jabato, Fernando M., Perkins, James R., Córdoba-Caballero, José, García-Criado, Federico, Sillitoe, Ian, Orengo, Christine, Ranea, Juan A. G., Seoane-Zonjic, Pedro“…Code maintained at https://github.com/ElenaRojano/DomFun. Validation procedure scripts can be found at https://github.com/ElenaRojano/DomFun_project. …”
Publicado 2022
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27067por Chen, Zhihao, Li, Liubing, Li, Ziyuan, Wang, Xi, Han, Mingxiao, Gao, Zongshuai, Wang, Min, Hu, Gangfeng, Xie, Xiaolu, Du, Hong, Xie, Zonggang, Zhang, Haifang“…Moreover we performed pathway enrichment analysis, constructed protein–protein interaction networks, and devised competitive endogenous RNA (ceRNA) networks. Biological targets of the ceRNA networks were evaluated and potential OS biomarkers confirmed by RT-qPCR analysis of the patients’ serum. …”
Publicado 2022
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27068“…DEGs were found to be mainly enriched in inflammation and immune-related signaling pathways through enrichment analysis. The ceRNA network included nine lncRNAs, 13 miRNAs, and 21 mRNAs. …”
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27069por Tian, Weihua, Hao, Xin, Nie, Ruixue, Ling, Yao, Zhang, Bo, Zhang, Hao, Wu, Changxin“…We also constructed a competing endogenous RNA (ceRNA) network based on the key lncRNAs, differentially expressed miRNAs, and differentially expressed mRNAs. …”
Publicado 2022
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27070“…We predicted the potential genes and RNAs related to CRSWNP by constructing a ceRNA network. In addition, we also used 19 hub immune genes to predict the potential drugs of CRSWNP. lncRNA biomarkers in CRSwNP were identified by lncRNAs LASSO regression. …”
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27071“…METHODS: LASSO Cox regression analysis was conducted to construct a prognostic necroptosis-related signature. lncRNA–miRNA–mRNA regulatory axis was constructed with a ceRNA network. qRT-PCR was performed to verify our result. …”
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27072por Li, Zhen, Chen, Zhenyue, Wang, Xiaotan, Li, Zehui, Sun, He, Wei, Jinqiang, Zeng, Xianzhong, Cao, Xuewei, Wan, Chao“…After overlapping the brown module genes with miRNA–mRNA pairs, 27 miRNA–mRNA pairs were obtained. A ceRNA network was constructed with 5505 lncRNA–miRNA–mRNA interactions. …”
Publicado 2022
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27073por Yu, Hongjun, Wang, Chaoqun, Ke, Shanjia, Bai, Miaoyu, Xu, Yanan, Lu, Shounan, Feng, Zhigang, Qian, Baolin, Xu, Yue, Zhou, Menghua, Li, Zihao, Yin, Bing, Li, Xinglong, Hua, Yongliang, Zhou, Yongzhi, Pan, Shangha, Fu, Yao, Ma, Yong“…The correlations between CFHR4 expression levels in HCC and N6-methyladenosine (m6A) modifications and the competing endogenous RNA (ceRNA) regulatory networks were confirmed in TCGA cohort. …”
Publicado 2022
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27074“…Competing endogenous RNAs (ceRNA) regulation network was constructed to reveal their functions. …”
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27075“…The correlation between RAB39B and m6A-related genes in DLBCL was analyzed using TCGA data. The RAB39B ceRNA network was constructed based on starBase and miRNet2.0 databases. …”
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27076por Yuan, Feng, Tang, Yongchang, Cao, Mingbo, Ren, Yupeng, Li, Yuxuan, Yang, Gaoyuan, Ou, Qifeng, Tustumi, Francisco, Levi Sandri, Giovanni Battista, Raissi, Driss, Pocha, Christine, Deng, Meihai, Yao, Zhicheng“…Finally, through multi-data crossover analysis and data analysis of HCC samples further confirmed the existence of the hsa_circ_0039466/miR-96-5p/FOXO1 ceRNA regulatory network and that the axis was closely related to clinical stage. …”
Publicado 2022
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27077por Bai, Qiong, Shi, Min, Sun, Xinli, Lou, Qiu, Peng, Hangya, Qu, Zhuan, Fan, Jiashuang, Dai, Lifen“…Five modules were identified as key modules based on WGCNA, and an m6A regulator–target gene–pathway network and the ceRNA network were constructed in module brown. Moreover, three m6A regulators (FTO, YTHDF2, and CBLL1) were selected as the candidate genes for OP. …”
Publicado 2022
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27078por Tan, Zhibo, Chen, Min, Peng, Feng, Yang, Pengfei, Peng, Zhaoming, Zhang, Zhe, Li, Xin, Zhu, Xiaopeng, Zhang, Lei, Zhao, Yujie, Liu, Yajie“…Moreover, competing endogenous RNAs (ceRNAs) network were established using ENCORI, miRCancer, and Kaplan-Meier plotter. …”
Publicado 2022
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27079por Xie, Yongpeng, Luo, Jiye, Hu, Wenxia, Ye, Chongchong, Ren, Panpan, Wang, Yanli, Li, Xiaomin“…The DEGs of miRNA, cirRNA, lncRNA, and mRNA were screened using DESeq2 software, and the ceRNA regulatory network was constructed using Cytoscape. …”
Publicado 2022
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27080por Jiang, Hong, Zhang, Xia, Wu, Yalan, Zhang, Baozhu, Wei, Juanbing, Li, Jianhua, Huang, Yuxiu, Chen, Lihong, He, Xinqin“…Single gene GSEA result suggested that all five biomarkers were involved in labyrinthine layer morphogenesis and transmembrane transport-related biological processes in EM. A ceRNA regulatory network containing 184 nodes and 251 edges was constructed. …”
Publicado 2022
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