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27301“…Mechanistic analysis showed that LINC00665 might serve as a ceRNA for miR-149-3p to regulate the expression of RNF2. …”
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27302“…CONCLUSION: Therefore, HOTTIP acting as ceRNAs to promote testicular embryonal carcinoma cell proliferation.…”
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27303por Xi, Xiaoyu, Zou, Qin, Wei, Yingying, Chen, Yan, Wang, Xue, Lv, Daojun, Li, Peilin, Wen, Anxiang, Zhu, Li, Tang, Guoqing, Ma, Jideng, Li, Mingzhou, Li, Xuewei, Jiang, Yanzhi“…Multigroup cooperative control relationships were also assessed, and competing endogenous RNA (ceRNA) networks were constructed in the ovarian aging cycle. …”
Publicado 2019
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27304“…Mechanistically, circ-ENO1 acted as a ceRNA to interact with miR-22-3p and upregulate ENO1 expression. …”
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27305“…Potential mechanisms of competitive endogenous RNAs (ceRNAs) were predicted by using bioinformatics analysis and explored by western blot assay, fluorescence in situ hybridization assay, real-time quantitative PCR (RT-qPCR) array, RNA pull-down analysis, AGO2-RIP assay, and dual-luciferase reporter assay. …”
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27306por Shan, Weifeng, Chen, Wei, Zhao, Xian, Pei, Aijie, Chen, Manli, Yu, Yang, Zheng, Yueying, Zhu, Shengmei“…In summary, our results suggested that lncRNA TUG1 may function as a competing endogenous RNA (ceRNA) for miR‐145 to induce cell damage, possibly providing a new therapeutic target in cerebral ischaemia/reperfusion injury.…”
Publicado 2019
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27307por Xiao, Jian, Lin, Linling, Luo, Dakui, Shi, Liang, Chen, Wangwang, Fan, Hao, Li, Zengliang, Ma, Xiang, Ni, Peidong, Yang, Li, Xu, Zekuan“…Mechanistically, TRPM2-AS serves as a microRNA sponge or a competitive endogenous RNA (ceRNA) for tumor suppressive microRNA miR-612 and consequently modulates the derepression of IGF2BP1 and FOXM1. …”
Publicado 2020
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27308por He, Zhi, Yang, Deying, Fan, Xiaolan, Zhang, Mingwang, Li, Yan, Gu, Xiaobin, Yang, Mingyao“…In the development of liver fibrosis, some lncRNAs regulate diverse cellular processes by acting as competing endogenous RNAs (ceRNAs) and binding proteins. Previous investigations demonstrated that overexpression of lncRNAs such as H19, maternally expressed gene 3 (MEG3), growth arrest-specific transcript 5 (GAS5), Gm5091, NR_002155.1, and HIF 1alpha-antisense RNA 1 (HIF1A-AS1) can inhibit the progression of liver fibrosis. …”
Publicado 2020
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27309por Zhou, Rui, Sun, Huiying, Zheng, Siting, Zhang, Jingwen, Zeng, Dongqiang, Wu, Jianhua, Huang, Zhenhua, Rong, Xiaoxiang, Bin, Jianping, Liao, Yulin, Shi, Min, Liao, Wangjun“…The following cell infiltration and competing endogenous RNA (ceRNA) network functional analyses further confirmed the association between the SLS model and stromal activation‐related biological processes. …”
Publicado 2020
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27310“…Some lncRNAs are classified as competitive endogenous RNAs (ceRNAs) that bind to specific miRNAs to prevent interaction with target mRNAs. …”
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27311“…In this review, we summarized the main molecular mechanism of LncRNAs regulating NSCLC metastasis, including three aspects: (a) LncRNAs interact with miRNAs as ceRNAs; (b) LncRNAs bind with target proteins; and (c) LncRNAs participate in the transduction of different signal pathways. …”
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27312por Shen, Yifei, Xu, Jingwen, Pan, Xiaohui, Zhang, Yunkun, Weng, Yiping, Zhou, Dong, He, Shisheng“…Furthermore, using bioinformatics analysis, luciferase reporter, RNA immunoprecipitation, and RNA pull-down assay, we identified that KCNQ1OT1 functions as a competing endogenous RNA (ceRNA) by sponging miR-34c-5p, which inhibited ALDOA expression by directly targeting its 3ʹUTR. …”
Publicado 2020
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27313“…BACKGROUND: It has been proved that lncRNAs could function as CeRNA for miRNAs in tumor growth and metastasis for cervical cancer. …”
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27314“…Mechanically, LINC01094 was a ceRNA of CHEK2 by sponging miR-577. Also, the enhancement of LINC01094 on ccRCC radioresistance was mediated by CHEK2-stabilized FOXM1 protein. …”
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27315“…Mechanistically, we found that circITGA7 acts as miR-198 competitive endogenous RNA (ceRNA) to regulate FGFR1 expression. CONCLUSIONS: In summary, circRNA circITGA7 may play a regulatory role in TC and may be a potential marker for TC diagnosis or progression.…”
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27316por Huang, Lining, Jiang, Xingming, Li, Zhenglong, Li, Jinglin, Lin, Xuan, Hu, Zengtao, Cui, Yunfu“…Insights into the underlying mechanisms of competitive endogenous RNAs (ceRNAs) were determined by bioinformatics analysis, dual-luciferase reporter assays, qRT-PCR arrays, RNA immunoprecipitation (RIP) and rescue experiments. …”
Publicado 2020
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27317“…HP increased lncRNA-PAGBC, which is a competitive endogenous RNA (ceRNA) that binds to the osteogenesis-inhibitory microRNA, miR-133b, to regulate osteogenic differentiation of AMSCs. …”
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27318por Gu, Huijie, Cheng, Xiangyang, Xu, Jun, Zhou, Kaifeng, Bian, Chong, Chen, Guangnan, Yin, Xiaofan“…Mechanistic investigations suggested that circFAT1(e2) served as a competing endogenous RNA (ceRNA) of miR-181b to enhance HK2 expression. On the whole, our study indicated that circFAT1(e2) exerted oncogenic roles in OS and suggested the circFAT1(e2)/miR-181b/HK2 axis might be a potential therapeutic target.…”
Publicado 2020
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27319“…A coding-non-coding gene co-expression (CNC) network and competing endogenous RNA (ceRNA) network analysis revealed that the potential functions of these 10 DE lncRNAs were closely connected with the processes of the immune response. …”
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27320por Xu, Shun, Wang, Jin, Jiang, Jianyuan, Song, Jian, Zhu, Wei, Zhang, Fan, Shao, Minghao, Xu, Haocheng, Ma, Xiaosheng, Lyu, Feizhou“…This lncRNA functioned as a ceRNA for miR-1231-5p/Col1a1 axis and enhanced microglial pyroptosis after SCI by activating the PI3K/AKT pathway. …”
Publicado 2020
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