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27361por Yousefi, Maryam, Peymani, Maryam, Ghaedi, Kamran, Irani, Shiva, Etemadifar, Masoud“…The results of the expression profiles of six nodes of the two ceRNA networks shown that linc01128, hsa-miR-24-3p and hsa-miR-30c-5p expression were significantly downregulated. …”
Publicado 2022
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27362por Cercato, Maria Cecilia, Colella, Elvira, Fabi, Alessandra, Bertazzi, Isabella, Giardina, Barbara Giuseppa, Di Ridolfi, Paolo, Mondati, Mara, Petitti, Patrizia, Bigiarini, Liciano, Scarinci, Virginia, Franceschini, Alessandro, Servoli, Francesca, Terrenato, Irene, Cognetti, Francesco, Sanguineti, Giuseppe, Cenci, Cristina“…METHODS: We conducted a preliminary, open, uncontrolled, real-life study in the oncology and radiotherapy departments of Istituto di Ricovero e Cura a Carattere Scientifico National Cancer Institute Regina Elena, Rome, Italy. We recruited adult Italian-speaking patients who then completed the DNM diary from the start of treatment. …”
Publicado 2022
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27363por Shen, Ruoyi, Cai, Xin, Shen, Dan, Zhang, Ruochen, Zhang, Weijie, Zhang, Yang, Li, Yue, Wang, Anqi, Zeng, Yuanyuan, Zhu, Jianjie, Liu, Zeyi, Huang, Jian-an“…Moreover, miR-335-3p/CTHRC1 axis was intensively possible to be a critical regulator in the effect of LINC00518 on LUAD via visual ceRNA network. Importantly the progress of LUAD was relevant to the active CTHRC1 which was realized by the target of LINC00518 to miR-335-3p. …”
Publicado 2022
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27364“…Next, according to the mechanistic studies, circ‐0008003 functioned as a ceRNA of ZNF281 in NSCLC by acting as the endogenous sponge for miR‐488, which was proved to be a tumour suppressor in NSCLC. …”
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27365por Chen, Sheng“…Moreover, circ_000166 could act as the ceRNA of miR-296 and competitively bind to miR-296, leading to an increase in the expression of the SGLT2 gene regulated by miR-296. …”
Publicado 2022
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27366“…CircRNA can regulate the expression of target genes through competitive binding with microRNA, thus playing the biological role of endogenous RNA (CeRNA). Many studies have shown that circRNAs plays an important role in malignant tumors, autoimmune system diseases, coronary heart disease and other diseases. …”
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27367por Feng, Yifei, Wang, Xiaoyuan, Huang, Changzhi, Zhang, Dongsheng, Liu, Tingwei, Zhang, Chuan, Zhang, Yue, Ji, Dongjian, Tang, Junwei, Sun, Yueming“…Further study revealed that circTMEM59 played the role of competing endogenous RNAs (ceRNAs) by binding to miR-668-3p to increase the expression of inhibitor of DNA binding 4 (ID4) in CRC. …”
Publicado 2022
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27368por Yang, Yanyan, Li, Min, Liu, Yan, Wang, Zhibin, Fu, Xiuxiu, He, Xingqiang, Wang, Qi, Li, Xiao-xin, Ma, Huibo, Wang, Kun, Zou, Lu, Wang, Jian-xun, Yu, Tao“…Mechanistically, Punisher was further proved to serve as a ceRNA which directly binds to miR-664a-5p and consequently regulates its target OPA1, and finally contributes to the biological function of VSMCs. …”
Publicado 2022
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27369Georoutes as a Basis for Territorial Development of the Pacific Coast of South America: a Case Study“…This work aims to propose three geological routes (georoutes) in the Santa Elena province as a base for geotourism development. …”
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27370por Zhang, Long, Zhou, Changfan, Jiang, Xiaoyu, Huang, Shuntao, Li, Yiheng, Su, Tao, Wang, Guowei, Zhou, You, Liu, Min, Xu, Dequan“…Mechanistically, bioinformatics database prediction, luciferase screening, RNA immunoprecipitation (RIP), RNA-pull down, and FISH co-localization experiments revealed that the circ0001470 acted as a competing endogenous RNA (ceRNA) through sponging miR-140-3p to regulate downstream PTGFR expression. …”
Publicado 2022
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27371“…Then, we screened aberrantly methylated lncRNAs that negatively regulated lncRNA expression and mapped them to the ceRNA relationship for further validation. 29 lncRNAs were identified as diagnostic biomarkers for their corresponding cancer types, with lncRNA AC027601 was identified as a new KIRC-associated biomarker, and lncRNA ACTA2-AS1 was regarded as a carcinogenic factor of KIRP. …”
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27372“…INTRODUCTION: Competing endogenous RNA (ceRNA) appears to be an important post-transcriptional manner that regulates gene expression through a miRNA-mediated mechanism. …”
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27373“…The correlation between has-miR-150 and CASC1 (for the case of bladder cancer) was then analyzed, and the related ceRNA network was mapped. A negative relationship between CASC1 expression and has-miR-150 expression was found in cases of bladder cancer. …”
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27374por Solomonov, Aleksei V., Marfin, Yuriy S., Tesler, Alexander B., Merkushev, Dmitry A., Bogatyreva, Elizaveta A., Antina, Elena V., Rumyantsev, Evgeniy V., Shimanovich, Ulyana“…Merkushev, Elizaveta A. Bogatyreva, Elena V. Antina, Evgeniy V. Rumyantsev, and Ulyana Shimanovich “Spanning BODIPY fluorescence with self-assembled micellar clusters”, Colloids and Surfaces B: Biointerfaces, 216, 2022, 112532. …”
Publicado 2022
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27375por Chang, Cherry Yin-Yi, Yang, Li, Tse, Joe, Lo, Lun-Chien, Tseng, Chung-Chen, Sun, Li, Lai, Ming-Tsung, Chen, Ping-Ho, Hwang, Tritium, Chen, Chih-Mei, Tsai, Fuu-Jen, Sheu, Jim Jinn-Chyuan“…It has been known that UCA1 can function as a ceRNA to sponge and inhibit miRNAs, resulting in loss-of-control on downstream target genes. …”
Publicado 2022
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27376por Li, Yuan, Lei, Chiseng, Xie, Yude, Zhang, Jie, Wang, Ningxia, He, Weili, Qu, Shaohua“…Based on the 38 up-regulated circRNAs and 14 down-regulated circRNAs, we constructed competing endogenous RNA (ceRNA) networks, from which the has-miR-6794-5p has been identified to enriched in the up-regulated network and correlated with the circNFIX directly. …”
Publicado 2022
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27377“…Finally, we designed a hub competitive endogenous RNA(ceRNA) network of disease-associated lncRNAs, miRNAs, and mRNAs. …”
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27378por Feng, Junkai, Hu, Menglong, Li, Zongkuo, Hu, Guiming, Han, Yuting, Zhang, Yan, Zhang, Min, Ren, Jingli“…CKS2 upregulation was associated with the immune microenvironment, mRNA methylation, and competing endogenous RNAs (ceRNAs). CKS2 can serve as a diagnostic and prognostic biomarker for stages I–III invasive non-mucinous lung adenocarcinoma and modulate the effect of paclitaxel and carboplatin by regulating microtubule binding and influencing carboplatin binding to DNA.…”
Publicado 2022
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27379por Muñoz-Abril, Laia, Torres, Maria de Lourdes, Valle, Carlos A., Rubianes-Landázuri, Francisco, Galván-Magaña, Felipe, Canty, Steven W. J., Terán, Martin A., Brandt, Margarita, Chaves, Jaime A., Grewe, Peter M.“…A total of 164 yellowfin tuna from Cabo San Lucas, México, and the Galápagos Islands and Santa Elena, Ecuador, were analysed using 18,011 single nucleotide polymorphisms. …”
Publicado 2022
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27380“…Our data suggested that LINC00174 aggravated LUSC progression via serving as a competing endogenous RNA (ceRNA) to sponge miR-185-5p and ultimately upregulate NFIX, which offered a promising novel target for LUSC therapy.…”
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