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27601por Luo, Honglin, Yang, Huizan, Lin, Yong, Zhang, Yongde, Pan, Chuanyan, Feng, Pengfei, Yu, Yanling, Chen, Xiaohan“…LNC_000792, LNC_000215, LNC_000035 and LNC_000310, with cis and/or trans relationships with mRNAs, were also involved in ceRNA network. CONCLUSIONS: These results might represent the first identified expression profile of lncRNAs and mRNAs in tilapia macrophages activated by HSP70 and Sa.…”
Publicado 2017
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27602por Liu, Lingbin, Xiao, Qihai, Gilbert, Elizabeth R., Cui, Zhifu, Zhao, Xiaoling, Wang, Yan, Yin, Huadong, Li, Diyan, Zhang, Haihan, Zhu, Qing“…We also constructed a competing endogenous RNA (ceRNA) network by integrating competing relationships between protein-coding genes and lncRNA transcripts, and identified several lncRNA transcripts predicted to regulate the CASP6, CYP1B1, GADD45, MMP2, and SMAS2 genes. …”
Publicado 2018
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27603por Zhou, Zhixia, Lin, Zhijuan, He, Yuqi, Pang, Xin, Wang, Yin, Ponnusamy, Murugavel, Ao, Xiang, Shan, Peipei, Tariq, Muhammad Akram, Li, Peifeng, Wang, Jianxun“…This indicates that lncR-D63785 acts as a competitive endogenous RNA (ceRNA) of miR-422a and promotes chemoresistance by blocking miR-422-dependent suppression of MEF2D. …”
Publicado 2018
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27604por Han, Yawei, Hong, Yuheng, Li, Liandong, Li, Tengshuai, Zhang, Zhen, Wang, Jingzhao, Xia, Han, Tang, Yutao, Shi, Zhemin, Han, Xiaohui, Chen, Ting, Liu, Qi, Zhang, Mengxia, Zhang, Kun, Hong, Wei, Xue, Yuan“…An lncRNA-mRNA co-expression network, miRNA-mRNA target prediction network, and competing endogenous RNA (ceRNA) network of circRNA-miRNA-mRNA were constructed based on a correlation analysis of the differentially expressed RNA transcripts. …”
Publicado 2018
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27605por Zhu, Yuekun, Xing, Yanwei, Chi, Fengxu, Sun, Weidong, Zhang, Zhiyong, Piao, Daxun“…In addition, SNHG6 positively regulated FOXC1 expression through sponging miR-760 in CRC cells, thus indicating that SNHG6 exerted an oncogenic role in CRC by acting as a ceRNA of miR-760. CONCLUSION: Our results indicate that long non-coding RNA SNHG6 promotes colorectal cancer progression by sequestering miR-760 and activating FOXC1, our findings suggest that SNHG6 may serve as a potential therapeutic target for CRC.…”
Publicado 2018
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27606por Li, Ou, Li, Zhizhen, Tang, Qinghe, Li, Yesheng, Yuan, Shengxian, Shen, Yang, Zhang, Zhenghua, Li, Nianfeng, Chu, Kaijian, Lei, Guanglin“…LSINCT5 also served as a competing endogenous RNA (ceRNA) for miR-4516, resulting in increased STAT3/BclxL expression and attenuated apoptosis. …”
Publicado 2018
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27607por Rui, Xiaohui, Xu, Yun, Jiang, Xiping, Ye, Wenfeng, Huang, Yaqing, Jiang, Jingting“…LncRNA C5orf66-AS1, as a competitive endogenous RNA (ceRNA), regulated the effect of RING1 on the proliferation, apoptosis and cell cycle of cervical cancer cells through adsorbing miR-637. …”
Publicado 2018
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27608por Wang, Aihua, Hu, Jihong, Gao, Changbin, Chen, Guanglong, Wang, Bingcai, Lin, Chufa, Song, Liping, Ding, Yi, Zhou, Guolin“…Heat responsive lncRNA (TCONS_00048391) is an eTM for bra-miR164a, that could be a sponge for miRNA binding and may be a competing endogenous RNA (ceRNA) for the target gene NAC1 (Bra030820), affecting the expression of bra-miR164a in Chinese cabbage. …”
Publicado 2019
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27609por Liu, Xiaoli, Fu, Qingfeng, Li, Shijie, Liang, Nan, Li, Fang, Li, Changlin, Sui, Chengqiu, Dionigi, Gianlorenzo, Sun, Hui“…FOXD2-AS1 acts as a competitive endogenous RNA (ceRNA) for miR-7-5p, up-regulating the expression of telomerase reverse transcriptase (TERT), which further promotes the cancer stem cells features and anoikis resistance in thyroid cancer cells. …”
Publicado 2019
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27610“…The starBase datasets and Cytoscape was used to perform ceRNA (competitive endogenous RNA) network. RESULTS: We demonstrated ZFAS1 was highly expressed in thyroid cancer compared to normal samples. …”
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27611por Xu, Wu, Hu, Guo-Qing, Da Costa, Clive, Tang, Jun-Hai, Li, Qing-Rui, Du, Lei, Pan, Ya-Wen, Lv, Sheng-Qing“…Results: UBE2R2-AS1 acted as a competing endogenous RNA (ceRNA) to target Toll-like receptor 4 (TLR4) mRNA by binding to miR-877-3p. …”
Publicado 2019
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27612por Visioli, Alberto, Giani, Fabrizio, Trivieri, Nadia, Pracella, Riccardo, Miccinilli, Elide, Cariglia, Maria Grazia, Palumbo, Orazio, Arleo, Andrea, Dezi, Fabio, Copetti, Massimiliano, Cajola, Laura, Restelli, Silvia, Papa, Valerio, Sciuto, Antonio, Latiano, Tiziana Pia, Carella, Massimo, Amadori, Dino, Gallerani, Giulia, Ricci, Riccardo, Alfieri, Sergio, Pesole, Graziano, Vescovi, Angelo L., Binda, Elena“…FUND: This work was financially supported by grants from “Ministero della Salute Italiano”(GR-2011-02351534, RC1703IC36 and RC1803IC35) to Elena Binda and from “Associazione Italiana Cancro” (IG-14368) Angelo L. …”
Publicado 2019
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27613por Jia, Yunlong, Duan, Yuqing, Liu, Tianxu, Wang, Xuexiao, Lv, Wei, Wang, Mengjie, Wang, Jiali, Liu, Lihua“…Then, by using bioinformation analysis and luciferase reporter experiment, we identified that TTN-AS1 could function as a competing endogenous RNA (ceRNA) by sponging miR-142-5p to regulate the expression of cyclin-dependent kinase 5 (CDK5) in LUAD. …”
Publicado 2019
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27614“…A microarray (SBC human ceRNA array V1.0) was performed to assess the expression profiles and biological functions of lncRNAs, circRNAs and mRNAs in ESCC and para-cancerous tissues from three patients. …”
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27615por Chen, Yangzong, Bao, Chunchun, Zhang, Xiuxing, Lin, Xinshi, Huang, Hongou, Wang, Zhiqiang“…HCG11 was predominantly enriched in the cytoplasm of glioma cells and acted as a competing endogenous RNAs (ceRNAs) by sponging micro‐496 to upregulate cytoplasmic polyadenylation element binding protein 3 (CPEB3). …”
Publicado 2019
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27616por Hua, Yong-Qiang, Zhu, Yao-Dong, Xie, Guo-Qun, Zhang, Ke, Sheng, Jie, Zhu, Zhen-Feng, Ning, Zhou-Yu, Chen, Hao, Chen, Zhen, Meng, Zhi-Qiang, Liu, Lu-Ming“…Objective: This study is implemented to probe into the function of lncRNA SBF2-AS1 as a competing endogenous RNA (ceRNA) to sponge microRNA-142-3p (miR-142-3p) in modulating TWF1 expression in the gemcitabine resistance of pancreatic cancer. …”
Publicado 2019
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27617“…Experimental evidence, on the other hand, suggests that competing endogenous RNA (ceRNA) crosstalk is rather weak. Extended miRNA-RNA networks could however favour the integration of many crosstalk interactions, leading to significant large-scale effects in spite of the weakness of individual links. …”
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27618“…Through data analysis and experimental verification, we found MDM4, a regulatory factor in p53 pathway, was involved in this ceRNA network. Our findings demonstrated that SNHG12 served as a sponge for miR-129-5p to regulate the expression of MDM4 and p53 pathway in the development of ccRCC.…”
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27619por Wang, Wei, Ge, Liang, Xu, Xiao-Juan, Yang, Ting, Yuan, Yue, Ma, Xiao-Ling, Zhang, Xue-Hong“…Additionally, NEAT1 acted as a ceRNA of miR-144-3p, leading to EZH2 upregulation. …”
Publicado 2019
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27620“…CONCLUSION: KCNQ1OT1 serves as competing endogenous RNA (ceRNA) to up-regulate PCBP2 via sponging miR-145-5p in BC progression.…”
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