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  1. 27761
    “…CONCLUSIONS: CircCEP128 functions as a ceRNA for miR-145-5p, which could up regulates SOX11 and further promotes cell proliferation and inhibits cell apoptosis of bladder cancer.…”
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    Circular RNA CEP128 acts as a sponge of miR-145-5p in promoting the bladder cancer progression via regulating SOX11
  2. 27762
    “…Luciferase reporter gene assay, RIP assay, and rescue experiments demonstrated that DSCR8 functioned as a competing endogenous RNA (ceRNA) by sponging miR-485-5p in HCC cells. Furthermore, gain- and loss-of-function studies showed that miR-485-5p activated Wnt/β-catenin signal pathway by targeting Frizzled-7 (FZD7). …”
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    Long non-coding RNA DSCR8 acts as a molecular sponge for miR-485-5p to activate Wnt/β-catenin signal pathway in hepatocellular carcinoma
  3. 27763
    “…Based on the target prediction, we constructed a circRNA-miRNA-mRNA competing endogenous RNA (ceRNA) network and elucidated circRNAs through Kyoto Encyclopedia of Genes and Genomes and Gene Ontology analyses. …”
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    Expression Profile Analysis of Circular RNAs in Ovarian Endometriosis by Microarray and Bioinformatics
  4. 27764
    “…Some C. elegans lincRNAs play cis roles to modulate the expression of their neighboring genes, and several lincRNAs play trans roles as ceRNAs against microRNAs. We also examine the regulation of lincRNA expression by transcription factors, and we dissect the pathway by which two transcription factors, UNC-30 and UNC-55, together control the expression of linc-73. …”
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    Systematic evaluation of C. elegans lincRNAs with CRISPR knockout mutants
  5. 27765
    “…The competitive endogenous RNA (ceRNA) network, including 6 circRNAs, 47 miRNAs and 90 mRNAs, indicated that the potential “housekeeping” function of circRNAs is dysregulated in hepatic I/R injury. …”
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    Comprehensive circRNA expression profile during ischemic postconditioning attenuating hepatic ischemia/reperfusion injury
  6. 27766
    “…Mechanistically, vIRF1 inhibits p53 function to increase the expression of DNA methyltransferase 1 (DNMT1) and DNA methylation of the promoter of pre-miR-218-1, a precursor of miR-218-5p, and increases the expression of a long non-coding RNA OIP5 antisense RNA 1 (lnc-OIP5-AS1), which acts as a competing endogenous RNA (ceRNA) of miR-218-5p to inhibit its function and reduce its stability. …”
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    Oncogenic KSHV-encoded interferon regulatory factor upregulates HMGB2 and CMPK1 expression to promote cell invasion by disrupting a complex lncRNA-OIP5-AS1/miR-218-5p network
  7. 27767
    “…Further experiments revealed that ZEB1-AS1 acted as competing endogenous RNA (ceRNA) of miR-141-3p: forced expression of ZEB1-AS1 reduced the expression of miR-141-3p to activate Zinc-finger Ebox Binding Homeobox 1 (ZEB1) in RLE-6TN cells. …”
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    lncRNA ZEB1-AS1 promotes pulmonary fibrosis through ZEB1-mediated epithelial–mesenchymal transition by competitively binding miR-141-3p
  8. 27768
    “…Finally, we found that cTFRC acts as a competing endogenous RNA (ceRNA) for miR-107 to regulate TFRC expression. CONCLUSIONS: cTFRC may exert regulatory functions in BC and may be a potential marker of BC diagnosis or progression. …”
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    Circular RNA cTFRC acts as the sponge of MicroRNA-107 to promote bladder carcinoma progression
  9. 27769
    por Sun, Zhenyu, Zhang, Tianfang, Chen, Bo
    Publicado 2019
    “…Mechanistic investigations demonstrated that MALAT1, as a competing endogenous RNA (ceRNA), regulated osteosarcoma proliferation and metastasis through competitively binding to miR-34a/c-5p and miR-449a/b. …”
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    Long Non-Coding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1) Promotes Proliferation and Metastasis of Osteosarcoma Cells by Targeting c-Met and SOX4 via miR-34a/c-5p and miR-449a/b
  10. 27770
    “…Moreover, Rik‐201 and Rik‐203 functioned as the competing endogenous RNA (ceRNA) to repress the function of miR‐96 and miR‐467a‐3p, respectively, and modulate the expression of Sox6 to further regulate neural differentiation. …”
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    LncRNA Riken‐201 and Riken‐203 modulates neural development by regulating the Sox6 through sequestering miRNAs
  11. 27771
    “…Under the GGA scheme, there are three ferromagnetic-half-metal (FM-HM) materials, Bi(2)CrCoO(6), Bi(2)CrNiO(6) and Bi(2)FeNiO(6), and three FiM-HM materials, Bi(2)FeZnO(6), Bi(2)CrZnO(6) and Bi(2)CoZnO(6). With implementation of the Coulomb interaction correction (GGA + U), we find two stable half-metallic materials: Bi(2)CrNiO(6) and Bi(2)CrZnO(6). …”
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    Half-Metallic Property Induced by Double Exchange Interaction in the Double Perovskite Bi(2)BB′O(6) (B, B′ = 3d Transitional Metal) via First-Principles Calculations
  12. 27772
    “…CONCLUSIONS: WWC2-AS1 was highly expressed in RIF, may function as a ceRNA in the regulation of FGF2 by binding miR-16. …”
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    LncRNA WWC2-AS1 functions AS a novel competing endogenous RNA in the regulation of FGF2 expression by sponging miR-16 in radiation-induced intestinal fibrosis
  13. 27773
    “…Signaling to specific miRNAs by acting as endogenous sponge (ceRNA) was the main form that regulates the target gene expression during cardiac remodeling. …”
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    Long Noncoding RNAs in Pathological Cardiac Remodeling: A Review of the Update Literature
  14. 27774
    por Guan, Yong-jun, Ma, Jian-ying, Song, Wei
    Publicado 2019
    “…We used the robust rank aggregation method to identify differentially expressed circRNAs (DEcircRNAs) and a ceRNA network was constructed based on circRNA–miRNA pairs and miRNA–mRNA pairs. …”
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    Identification of circRNA–miRNA–mRNA regulatory network in gastric cancer by analysis of microarray data
  15. 27775
    “…In conclusion, our results revealed that PFAR functions as a competitive endogenous RNA (ceRNA) by acting as a sponge for miR-15a, revealing a potential regulatory network involving PFAR and miR-15a with a role in the modulation of YAP1-Twist expression. …”
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    LncRNA PFAR contributes to fibrogenesis in lung fibroblasts through competitively binding to miR-15a
  16. 27776
    por Yang, Jue, Zhang, Yongqiang, Song, Hui
    Publicado 2019
    “…We further found that RP11-424C20.2 may act as a competing endogenous RNA (ceRNA) to increase UHRF1 expression through sponging miR-378a-3p. …”
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    A disparate role of RP11-424C20.2/UHRF1 axis through control of tumor immune escape in liver hepatocellular carcinoma and thymoma
  17. 27777
    “…Meanwhile, a potential competing endogenous RNA (ceRNA) mechanism through a circRNA-miRNA-mRNA network was applied to annotate potential functions of these common differentially expressed circRNAs, and these predicted miRNAs or mRNAs might be involved in nigericin damage. …”
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    High-throughput sequencing of circRNAs reveals novel insights into mechanisms of nigericin in pancreatic cancer
  18. 27778
    “…Finally, we enrolled the differentially expressed mRNAs derived from the identical spinal cord, these validated circRNAs and their putative miRNA targets for ceRNA analysis and screened a promising circRNA-miRNA-mRNA pathway in the development of morphine tolerance. …”
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    Circular RNA expression profile in the spinal cord of morphine tolerated rats and screen of putative key circRNAs
  19. 27779
    “…Wound healing, Transwell assays, flow cytometry, Western blot, luciferase reporter assay and RNA immunoprecipitation (RIP) results demonstrated lncRNA HCP5 acted as a ceRNA to regulate GEM-resistance PC cells’ proliferation, invasion, migration, cell apoptosis and autophagy by targeting HDGF via miR-214-3p. …”
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    Long Noncoding RNA HCP5 Regulates Pancreatic Cancer Gemcitabine (GEM) Resistance By Sponging Hsa-miR-214-3p To Target HDGF
  20. 27780
    “…Downregulated expression of LINC01093 was associated with poor prognosis. A ceRNA network involving LINC01093, miR-96-5p and zinc finger AN1-type containing 5 (ZFAND5) was established. …”
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    Integrated bioinformatics analysis reveals role of the LINC01093/miR-96-5p/ZFAND5/NF-κB signaling axis in hepatocellular carcinoma
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