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27841por Huang, Zi-Li, Huang, Xiu-Yan, Huang, Jin, Huang, Xin-Yu, Xu, Yong-Hua, Zhou, Jian, Tang, Zhao-You“…Moreover, we also constructed competing endogenous RNA (ceRNA) network to identify key circRNAs involved in HCC. …”
Publicado 2021
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27842por Kang, Xueran, Chen, Yisheng, Yi, Bin, Yan, Xiaojun, Jiang, Chenyan, Chen, Bin, Lu, Lixing, Sun, Yuxing, Shi, Runjie“…Moreover, the screened pRS-related ceRNA network and circ_0002951/miR-548k/HAS2 pathway provide potential therapeutic targets and biomarkers of laryngocarcinoma. …”
Publicado 2021
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27843“…Moreover, inhibition of CASC19 weakened proinflammatory cytokine (IL-6, IL-8, and TNF-α) production and cell apoptosis but facilitated cell viability. Experiments of the ceRNA mechanism elucidated that miR-152-3p was a sponge for CASC19, and miR-152-3p targeted DDX6, suggesting that CASC19 sponged miR-152-3p to release DDX6. …”
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27844por Saini, Mohit Kumar, Sebastian, Aswathy, Shirotori, Yoshiki, Soulier, Nathan T., Garcia Costas, Amaya M., Drautz-Moses, Daniela I., Schuster, Stephan C., Albert, Istvan, Haruta, Shin, Hanada, Satoshi, Thiel, Vera, Tank, Marcus, Bryant, Donald A.“…Light harvesting is accomplished by the bacteriochlorophyll a-binding, Fenna-Matthews-Olson protein and chlorosomes containing bacteriochlorophyll c. …”
Publicado 2021
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27845por Wu, Wensi, Peng, Yongpai, Zhou, Jiaxin, Zhang, Xiaojun, Cao, Lin, Lin, Wei-jye, Lu, Yanan, Wen, Jing, Wang, Zhi“…The construction of competitive endogenous RNA (ceRNA) networks and the identification of hub genes provided possible therapeutic targets for PND. …”
Publicado 2021
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27846“…CONCLUSIONS: Therefore, MCM3AP-AS1 may serve as a competing endogenous RNA (ceRNA) of miR-126 to upregulate VEGF, thereby regulating cancer cell behaviors in EC.…”
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27847por Wang, Anpeng, Zhang, Te, Wei, Wei, Wang, Hui, Zhang, Zeyu, Yang, Wenming, Xia, Wenjie, Mao, Qixing, Xu, Lin, Jiang, Feng, Dong, Gaochao“…In summary, this work elucidates that LINC00665 accelerates LUAD progression via the miR-195-5p/MYCBP axis by acting as a competing endogenous RNA (ceRNA), suggesting that LINC00665 may represent a potential therapeutic target for clinical intervention of LUAD.…”
Publicado 2021
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27848por Huang, Tianzao, Chen, Yingxian, Zeng, Yile, Xu, Chaoyang, Huang, Jinzhong, Hu, Weipeng, Chen, Xiangrong, Fu, Huangde“…Furthermore, PSMA3-AS1 could act as a competitive endogenous RNA (ceRNA) for miR-411-3p to regulate HOXA10 and thus affecting glioma progression. …”
Publicado 2021
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27849“…The RNA-pull down assay and luciferase assay demonstrated that HAGLR functioned as a ceRNA of miR-130a-3p in SH-SY5Y cells. Overexpression of miR-130a-3p effectively inhibited SH-SY5Y differentiation. …”
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27850“…Circular RNAs (circRNAs) are a form of ncRNA, characterised by a closed loop structure with roles as competing endogenous RNAs (ceRNAs), protein interactors and transcriptional regulators. …”
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27851por Wu, Jun-yi, Qin, Jun, Li, Lei, Zhang, Kun-dong, Chen, Yi-sheng, Li, Yang, Jin, Tao, Xu, Jun-ming“…In addition, PPI and drug-ceRNA networks based on differences in BCPRS were constructed. …”
Publicado 2021
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27852por Kang, Yujuan, Wan, Lin, Wang, Qin, Yin, Yanling, Liu, Jiena, Liu, Lei, Wu, Hao, Zhang, Lei, Zhang, Xin, Xu, Shouping, Pang, Da“…Mechanistically, SNHG1 functioned as a competing endogenous RNA (ceRNA) to promote TERT expression by sponging miR-18b-5p in breast cancer. miR-18b-5p acted as a tumor repressor in breast cancer. …”
Publicado 2021
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27853por Wei, Huamei, Tang, Qianli, Wang, Anmin, Zhang, Ya, Qin, Zebang, Li, Wenchuan, Xu, Zuoming, Wang, Jianchu, Pu, Jian“…MAGI2-AS3 serves as competing endogenous RNA (ceRNA) of miR-519c-3p to regulate TXNIP in HCC. And, TXNIP upregulation weakened the influence of MAGI2-AS3 knockdown on HCC cell behaviors. …”
Publicado 2021
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27854“…Mechanism exploration indicated that circ_RPPH1 acted as ceRNA (competing endogenous RNA) of miR-146b-3p, so as to reduce the inhibitory role of miR-146b-3p on its target E2F2. …”
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27855por Luo, Haixia, Li, Yuanxing, Zhao, Yueyang, Chang, Jingjing, Zhang, Xiu, Zou, Binbin, Gao, Lifang, Wang, Wei“…Subsequently, a competing endogenous RNA (ceRNA) network analysis and real-time PCR validation indicated that hsa_circ_0001955/hsa-miR-6719-3p/CDK1, hsa_circ_0001955/hsa-miR-1277-5p/NEDD4L and hsa_circ_0003954/hsa-miR-15a-3p/SYCP2 were highly correlated with cervical carcinogenesis. …”
Publicado 2021
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27856por Zhou, Yongfang, Zhang, Fei, Xu, Fengyang, Wang, Qiang, Wu, Jianhua, Peng, Wuxun, Dong, Wentao“…In conclusion, lncRNA NEAT1 as a ceRNA can adsorb miR-23b-3p and promote the expression of CYP1A2, which then inhibits the osteogenic differentiation of hBMSCs and promotes the progress of SNFH.…”
Publicado 2021
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27857“…The functional prediction results showed that novel_circ_0001608 and novel_circ_0002886, competing to bind with dre-miR-153b-5p and dre-miR-124-6-5p, might act as competing endogenous RNAs (ceRNAs) to control MamblycephalaGene14755 (pik3r1) and MamblycephalaGene10444 (apip) level, respectively, thus playing an important regulatory role in muscle growth. …”
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27858por Zhou, Junliang, Zhang, Mingyan, Dong, Huanhuan, Wang, Meiqi, Cheng, Yue, Wang, Shuqing, Ma, Wenbo, Xu, Hui“…We found that AC099850.3 was significantly higher in both cluster 1 and high-risk subgroups, which may serve as a potential biomarker for the prognosis of NSCLC patients. Then, based on ceRNA competition mechanisms, the pathway enrichment of 105 acetylation-related lncRNAs was conducted by GO and KEGG analyses. …”
Publicado 2021
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27859Robust Glycogene-Based Prognostic Signature for Proficient Mismatch Repair Colorectal Adenocarcinomapor Li, Yixi, Li, Dehua, Chen, Yang, Lu, Yongping, Zhou, Fangbin, Li, Chunhong, Zeng, Zhipeng, Cai, Wanxia, Lin, Liewen, Li, Qiang, Ye, Mingjun, Dong, Jingjing, Yin, Lianghong, Tang, Donge, Zhang, Gong, Dai, Yong“…RESULTS: We constructed a competing endogenous RNA (ceRNA) regulatory network using RNA-seq. Genes associated with glycosylation pathways were embedded within this scale-free network. …”
Publicado 2021
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27860“…Cell proliferation, cell migration, and xenograft tumor assays were performed to verify the function of LINC00265 subjected to overexpressing and silencing experiments. The ceRNA mechanism with LINC00265/miR-4500/STAT3 was investigated through luciferase and RNA pull-down assays. …”
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