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28161por Tiansheng, Guo, Junming, Huang, Xiaoyun, Wan, Peixi, Chen, Shaoshan, Du, Qianping, Chen“…Next, we verified that MALAT1 could act as a competing endogenous RNA (ceRNA) by sponging miR-202 in NSCLC and there is a negative correlation between MALAT1 and miR-202. …”
Publicado 2020
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28162por Deng, Guangxu, Mou, Tingyu, He, Jiayong, Chen, Da, Lv, Daojun, Liu, Hao, Yu, Jiang, Wang, Shuang, Li, Guoxin“…CONCLUSION: Taken together, this study revealed that circRHOBTB3 might function as competing endogenous RNA (ceRNA) for miR-654-3p, which could contribute to growth inhibition of GC through activating p21 signaling pathway. …”
Publicado 2020
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28163por He, Yiren, Wang, Yinfeng, Liu, Liu, Liu, Shaojun, Liang, Lichuan, Chen, Yinan, Zhu, Zhiqiang“…Furthermore, mechanistic investigations suggested that circ_0006282 served as a competing endogenous RNA (ceRNA) of miR-155. Moreover, FBXO22 was identified as the functional target of miR-155 and down-expression of circ_0006282 inhibited FBXO22 expression. …”
Publicado 2020
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28164por Zhao, Ranran, Liu, Nan, Han, Fuhui, Li, Hegang, Liu, Jifeng, Li, Lanlan, Wang, Guoyi, He, Jianning“…Circular RNAs (circRNAs) are widely expressed non-coding RNAs that can act as competitive endogenous RNAs (ceRNAs) to bind to miRNAs. Although circRNAs have been studied in many fields, research on their activity in sheep wool follicles is limited. …”
Publicado 2020
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28165“…In other words, NEAT1 acted as a competing endogenous RNA (ceRNA), regulating the miR-34b-5p-GLI1 axis, further affecting the proliferation of DLBCL. …”
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28166“…ZEB1-AS1 has a negative correlation with miR-133a-3p and a positive association with LPAR3 and EGFR through ceRNA analysis. Importantly, ZEB1-AS1 boosted the proliferation and suppressed the apoptosis in TC cells. …”
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28167por Qi, Ying, He, Li, Cui, Xiaohong, Hertel, Laura, Freed, Daniel C., Fu, Tong-Ming, Kauvar, Lawrence M., McVoy, Michael A., Ruan, Qiang“…That certain sera exhibit similar discordances between neutralizing potencies measured using epithelial vs. endothelial cells (Gerna G. et al.J Gen Virol, 89:853–865, 2008) suggested that additional mechanistic differences may also exist between epithelial and endothelial cell entry. …”
Publicado 2020
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28168por Bai, Minghua, Lei, Yutiantian, Wang, Mincong, Ma, Jinlu, Yang, Pengtao, Mou, Xingyi, Dong, Yiping, Han, Suxia“…Mechanically, SNHG17 functioned as a competing endogenous RNA (ceRNA) to up-regulate CD51 expression through competitively sponging microRNA-144 (miR-144), and CD51 was identified as a direct downstream target of miR-144 in CRPC. …”
Publicado 2020
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28169por Luo, Zai, Rong, Zeyin, Zhang, Jianming, Zhu, Zhonglin, Yu, Zhilong, Li, Tengfei, Fu, Zhongmao, Qiu, Zhengjun, Huang, Chen“…Mechanistic analysis demonstrated that circCCDC9 acted as a “ceRNA” of miR-6792-3p to relieve the repressive effect of miR-6792-3p on its target CAV1, then suppressed the tumorigenesis of GC. …”
Publicado 2020
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28170“…Mechanistically, circ-MAT2B was dominantly located in the cytoplasm and acted as a ceRNA to sponge miR-515-5p and increase HIF-1α expression. …”
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28171“…Importantly, an miRNA-mediated competitive endogenous RNA (ceRNA) network was successfully constructed based on the expression profiles of DElncRNAs and DEmRNAs. …”
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28172“…CONCLUSIONS: H3K27ac‐activated LINC00519 acts as a competing endogenous RNA (ceRNA) to promote LUSC progression by targeting miR‐450b‐5p/miR‐515‐5p/YAP1 axis.…”
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28173por Weng, Wanqing, Zhang, Zhongjing, Huang, Weiguo, Xu, Xiangxiang, Wu, Boda, Ye, Tingbo, Shan, Yunfeng, Shi, Keqing, Lin, Zhuo“…CONCLUSIONS: A novel competitive endogenous RNA (ceRNA) network associated with progression of PAAD could be used as a reference for future molecular biology research.…”
Publicado 2020
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28174“…Analysis of the lncRNA-miRNA-mRNA competing endogenous RNA (ceRNA) network between primed, naive hPSCs and EPS cells revealed that hsa-miR-424-5p, has-miR-16-5p, has-miR-27b-3p, has-miR-29c-3p, and KCNQ1OT1 were crucial nodes with high degrees of connectivity. …”
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28175“…Long non-coding RNAs (lncRNAs), as competing endogenous RNAs (ceRNAs), bind to microRNAs (miRNAs) to regulate various biological processes. …”
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28176por Tu, Zewei, Wu, Lei, Wang, Peng, Hu, Qing, Tao, Chuming, Li, Kuangxun, Huang, Kai, Zhu, Xingen“…We also establish a competing endogenous RNA (ceRNA) network based on seven of the twenty-four m6A-related lncRNAs. …”
Publicado 2020
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28177“…Notably, hsa_circ_0000517 regulated SMAD6 expression via acting as a competing endogenous RNA (ceRNA) for miR-326. And the repressive influence on malignant behaviors of HCC cells mediated by hsa_circ_0000517 inhibition was reversed by miR-326 inhibitors. …”
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28178por He, Hui, Wang, Yawei, Ye, Peng, Yi, Dehui, Cheng, Ying, Tang, Haibo, Zhu, Zhi, Wang, Xun, Jin, Shi“…ZFPM2-AS1 regulated the progression of HCC by acting as a competing endogenous RNA (ceRNA) to competitively bind to miR-139 and regulate GDF10 expression. …”
Publicado 2020
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28179“…Here, we further investigated its role in PDAC cells, as well as its mechanism via serving as competing endogenous RNA (ceRNA) for miRNA (miR)-7-5p, which is abundant in pancreas and suppresses the development of PDAC. …”
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28180“…Circular RNAs (circRNAs) are a special type of noncoding RNAs involved in competing endogenous RNA (ceRNA) network, a classic molecular mechanism of the tumorigenesis of human cancers, including BCa. …”
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