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521“…Objective: To construct ceRNA network and identify pivotal competing endogenous RNAs (ceRNAs) in adrenocortical carcinoma (ACC) using ceRNA network analysis. …”
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522“…The “competitive endogenous RNA (ceRNA)” hypothesis states that lncRNAs competitively bind to miRNAs through their intramolecular miRNA reaction elements (MREs) to construct a wide range of ceRNA regulatory networks. …”
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523Construction and Investigation of a lncRNA-Associated ceRNA Regulatory Network in Cholangiocarcinomapor Long, Junyu, Xiong, Jianping, Bai, Yi, Mao, Jinzhu, Lin, Jianzhen, Xu, Weiyu, Zhang, Hui, Chen, Shuguang, Zhao, Haitao“…Then, a dysregulated lncRNA-related ceRNA network was established by using four public databases. …”
Publicado 2019
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524por Huang, Runzhi, Wu, Jiawen, Zheng, Zixuan, Wang, Guanghua, Song, Dianwen, Yan, Penghui, Yin, Huabin, Hu, Peng, Zhu, Xiaolong, Wang, Haiyun, Lv, Qi, Meng, Tong, Huang, Zongqiang, Zhang, Jie“…Nine of 28 ceRNAs were found to be significant in the Kaplan–Meier analysis. …”
Publicado 2019
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525“…Moreover, gene oncology enrichment analyses for the genes in the ceRNA network were implemented and novel prognostic biomarker lncRNA molecules were identified. …”
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526“…Upon combined biological prediction, a total of 11 differentially expressed circRNAs, 15 differentially expressed miRNAs, and 560 target genes were screened to construct a circRNA-related ceRNA network. GO analysis and KEGG pathway analysis were performed for the 560 target genes. …”
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527por Irgen-Gioro, Shawn, Gururangan, Karthik, Saer, Rafael G., Blankenship, Robert E., Harel, Elad“…Here, we extract the electronic coherence lifetime and frequency using a signal subtraction procedure in two model pigment-protein-complexes (PPCs), light harvesting complex II (LH2) and the Fenna–Matthews–Olson complex (FMO), and find that the coherence lifetimes occur at the same timescale (<100 fs) as energy transport between states at the energy level difference equal to the coherence energy. …”
Publicado 2019
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528“…The present study successfully constructed a circRNA-miRNA-mRNA competing endogenous RNA (ceRNA) network based on four circRNAs, six miRNAs and 111 mRNAs in PDAC. …”
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529“…The gene expression matrix of GSE120356 was calculated by Pearson correlation coefficient, and the 11696 pairs of ceRNA relation were determined. In the ceRNA network, 643 lncRNAs and 147 mRNAs showed methylation difference. …”
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530por Sun, Chong-Bing, Wang, Hong-Yi, Han, Xiao-Qing, Liu, Yong-Ning, Wang, Meng-Chun, Zhang, Hong-Xia, Gu, You-Feng, Leng, Xiao-Gang“…CONCLUSION: These data demonstrate that LINC00511 promotes gastric cancer cell growth by acting as a ceRNA to regulate the miR-124-3p/PDK4 axis, which may be a promising therapeutic target for GC.…”
Publicado 2020
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531por Chen, Yixin, Sun, Feifei, Zhang, Yong, Song, Guang, Qiao, Wei, Zhou, Ke, Ren, Sihua, Zhao, Qian, Ren, Weidong“…Furthermore, functional annotation analysis and protein-protein interaction (PPI) network were carried out to investigate the potential key pathways and identify hub genes in CP. Subsequently, a ceRNA network was established and the key circRNAs were determined by Gene Set Enrichment Analysis (GSEA). …”
Publicado 2020
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532por Chang, Zhengyan, Huang, Runzhi, Fu, Wanting, Li, Jiehan, Ji, Guo, Huang, Jinglei, Shi, Weijun, Yin, Huabin, Wang, Weifeng, Meng, Tong, Huang, Zongqiang, Wei, Qing, Qin, Huanlong“…The metastasis-specific ceRNAs (competitive endogenous RNAs) and tumor-infiltrating immune cells might associate with tumor prognosis and distance metastasis. …”
Publicado 2020
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533por Wang, Qiu‐Yu, Peng, Liu, Chen, Yang, Liao, Lian‐Di, Chen, Jia‐Xin, Li, Meng, Li, Yan‐Yu, Qian, Feng‐Cui, Zhang, Yue‐Xin, Wang, Fan, Li, Chun‐Quan, Lin, De‐Chen, Xu, Li‐Yan, Li, En‐Min“…To systematically pinpoint functional lncRNAs, a computational approach was proposed for identification of lncRNA‐mediated competing endogenous RNAs (ceRNAs) through combining global and local regulatory direction consistency of expression. …”
Publicado 2020
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534“…BACKGROUND: The purpose of this study was to investigate the regulatory mechanisms of ceRNAs in breast cancer (BC) and construct a new five-mRNA prognostic signature. …”
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535“…MATERIAL AND METHODS: In the present work, we constructed relapse-related lncRNA-mediated ceRNA networks in HL. Additionally, we constructed co-expression networks for these relapse-related lncRNAs. …”
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536por Pakwan, Chonthicha, Chitov, Thararat, Chantawannakul, Panuwan, Manasam, Manop, Bovonsombut, Sakunnee, Disayathanoowat, TerdEnlace del recurso
Publicado 2020
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537por Jiang, Zhijun, Zhang, Yu, Liu, Xinyu, Liang, Jingchen, Qiu, Guanhua, Zhu, Xiaoqi, Chen, Jie, Li, Lequn“…Further, we effectively constructed a ceRNA network. The ceRNA network regulated by circ_0130911 might influence the prognosis of HCC by regulating cell cycle-related pathways. …”
Publicado 2020
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538por Jiang, Aimin, Liu, Na, Bai, Shuheng, Wang, Jingjing, Gao, Huan, Zheng, Xiaoqiang, Fu, Xiao, Ren, Mengdi, Zhang, Xiaoni, Tian, Tao, Ruan, Zhiping, Yao, Yu, Liang, Xuan“…A competing endogenous RNA (ceRNA) network was constructed to identify the hub genes involved in the prognosis of BLCA. …”
Publicado 2020
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539“…Finally, we constructed a competitive endogenous RNA (ceRNA) regulation network among lncRNAs, miRNAs, and mRNAs. …”
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540“…In IDD, multiple competing endogenous RNAs (ceRNA, including mRNA, lncRNA, and pseudogenes) can compete to bind with miRNAs. …”
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