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661por Sun, Yunhao, Qiu, Limin, Chen, Jinjin, Wang, Yao, Qian, Jun, Huang, Lirong, Ma, Haitao“…Based on the mechanism that circRNAs could play as ceRNAs to modulate targets expression, circRNA-miRNA and circRNA-miRNA-mRNA networks were constructed in this study. …”
Publicado 2020
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662Comprehensive analysis of TPX2-related ceRNA network as prognostic biomarkers in lung adenocarcinomapor Huo, Chen, Zhang, Meng-Yu, Li, Rui, Zhou, Xi-Jia, Liu, Ting-Ting, Li, Jian-Ping, Liu, Xiao, Qu, Yi-Qing“…Background and aim: Competing endogenous RNA (ceRNA) is believed to play vital roles in tumorigenesis. …”
Publicado 2020
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663“…Then, we established a ceRNA network related to autophagy genes. RESULTS: We screened out 27 differentially expressed genes which were enriched in GO and KEGG pathways related to autophagy and cancers. …”
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664por Fan, Feifei, Ping, Yu, Yang, Li, Duan, Xiaoran, Resegofetse Maimela, Nomathamsanqa, Li, Bingjie, Li, Xiangnan, Chen, Jing, Zhang, Kai, Wang, Liping, Liu, Shasha, Zhao, Xuan, Wang, Hongmin, Zhang, Yi“…Although competing endogenous RNA (ceRNA)‐based profiling has been investigated in patients with LUAD, it has not been specifically used to study metastasis in LUAD. …”
Publicado 2020
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665por Braga, Eleonora A., Fridman, Marina V., Moscovtsev, Alexey A., Filippova, Elena A., Dmitriev, Alexey A., Kushlinskii, Nikolay E.“…Our review focuses on the analysis of regulatory long non-coding RNAs (lncRNAs) competing with protein-coding mRNAs for binding to miRNAs according to the model of competitive endogenous RNA (ceRNA) in OvCa. Analysis of publications showed that most lncRNAs acting as ceRNAs participate in OvCa progression: migration, invasion, epithelial-mesenchymal transition (EMT), and metastasis. …”
Publicado 2020
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666por Wang, Shengran, Tang, Xia, Qin, Litao, Shi, Weili, Bian, Shasha, Wang, Zhaokun, Wang, Qingqing, Wang, Xin, Gu, Jianqin, Hao, Bingtao, Ding, Keyue, Liao, Shixiu“…Accumulating evidence suggests that circular RNAs (circRNAs)—miRNA–mRNA ceRNA regulatory network—may play an important role in neurological disorders, such as Alzheimer’s disease (AD). …”
Publicado 2020
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667Cerina: systematic circRNA functional annotation based on integrative analysis of ceRNA interactions“…Pareto Frontier Analysis was employed to integrate ENCODE mRNA/miRNA data with predicted microRNA response elements to prioritize tissue-specific ceRNA interactions. Using data from several circRNA-disease databases, we demonstrated that Cerina significantly improved the functional relevance of the prioritized ceRNA interactions by several folds, in terms of precision and recall. …”
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668por Liu, Guangdong, Liu, Danian, Huang, Jingjing, Li, Jianxin, Wang, Chuang, Liu, Guangyao, Ge, Shiqiang, Gong, Haidong“…BACKGROUND: Long intergenic non-coding RNAs (lincRNAs) are capable of regulating several tumours, while competitive endogenous RNA (ceRNA) networks are of great significance in revealing the biological mechanism of tumours. …”
Publicado 2021
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669“…Bioinformatics algorithms were used to construct a network of ovarian endometriosis-related competing endogenous RNAs (ceRNAs) and to detect functional lncRNAs. RESULTS: A total of 4,213 mRNAs, 1,474 lncRNAs, and 221 miRNAs were identified as being differentially expressed between EC and EU samples, and an ovarian endometriosis-related ceRNA network was constructed through analysis of these differentially expressed RNAs. …”
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670“…Circular RNAs (circRNAs) have been reported to play important roles in various cardiovascular diseases and can function as competitive endogenous RNAs (ceRNAs). However, their role in human DCM has not been fully elucidated. …”
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671“…Long noncoding RNAs (lncRNAs) can act as microRNA (miRNA) sponges to regulate protein-coding gene expression and therefore form a competing endogenous RNA (ceRNA) network. ceRNA networks have been proven to play vital roles during tumorigenesis and progression. …”
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672por Stecher, David, Hoogewerf, Marieke, Bronkers, Glenn, van Putte, Bart P., Doevendans, Pieter A., Tulleken, Cornelis A.F., van Herwerden, Lex, Pasterkamp, Gerard, Buijsrogge, Marc P.“…OBJECTIVE: This preclinical study determines the feasibility and 6-month patency rates of a new distal coronary connector, the Excimer Laser Assisted Nonocclusive Anastomosis (ELANA) Heart Bypass. METHODS: Twenty Dutch Landrace pigs received either a hand-sewn (n = 8) or an ELANA (n = 12) left internal thoracic artery to left anterior descending artery anastomosis, using off-pump coronary artery bypass grafting. …”
Publicado 2021
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673“…AIM: This study investigates the prophylactic effect of henna on the occurrence of hand-foot syndrome (HFS) in patients receiving capecitabine for breast and colorectal cancer. …”
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674por De Martino, M. Teresa, Tonin, Fabio, Yewdall, N. Amy, Abdelghani, Mona, Williams, David S., Hanefeld, Ulf, Rutjes, Floris P. J. T., Abdelmohsen, Loai K. E. A., van Hest, Jan C. M.“…Furthermore, as proof of principle, we demonstrated the successful implementation of different c-CLEnAs in a flow reactor in which the c-CLEnA nanoreactors retained their full catalytic function even after ten runs. …”
Publicado 2020
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675por Qian, Da, Zheng, Qinghui, Wu, Danping, Ye, Buyun, Qian, Yangyang, Zhou, Tao, Qiu, Jie, Meng, Xuli“…Nonetheless, potential roles of ceRNAs in regulating the metastasis of breast cancer remain unclear. …”
Publicado 2021
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676por Zhang, Yuanfu, Han, Peng, Guo, Qiuyan, Hao, Yangyang, Qi, Yue, Xin, Mengyu, Zhang, Yafang, Cui, Binbin, Wang, Peng“…Competing endogenous RNAs (ceRNA) are transcripts that communicate with and co-regulate each other by competing for the binding of shared microRNAs (miRNAs). …”
Publicado 2021
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677por Liu, Xu-Sheng, Gao, Yan, Wu, Li-Bing, Wan, Hua-Bing, Yan, Peng, Jin, Yang, Guo, Shi-Bo, Wang, Ya-Lan, Chen, Xue-Qin, Zhou, Lu-Meng, Yang, Jian-Wei, Kui, Xue-Yan, Liu, Xiao-Yu, Pei, Zhi-Jun“…Six possible crRNA networks in ESCA were constructed by correlation analysis, and all these ceRNA networks contained GLUT1. CONCLUSION: GLUT1 can be used as a biomarker for the diagnosis and treatment of ESCA, and is related to tumor immune infiltration, m6A modification and ceRNA network.…”
Publicado 2021
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678por Shi, Deyao, Mu, Shidai, Pu, Feifei, Zhong, Binlong, Hu, Binwu, Liu, Jianxiang, He, Tongchuan, Zhang, Zhicai, Shao, Zengwu“…However, the role of the ceRNA regulatory network in the TME of sarcoma remains unclear. …”
Publicado 2021
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679por Qin, Ya-Fei, Li, Guang-Ming, Wang, Grace, Kong, De-Jun, Wang, Hong-Da, Zhao, Yi-Ming, Hao, Jing-Peng, Qin, Hong, Sun, Da-Qing, Wang, Hao“…OBJECTIVE: This study aimed to discover the ceRNAs network in the pathophysiological development of human colorectal cancer (CRC) and to screen biomarkers for target therapy and prognosis by using integrated bioinformatics analysis. …”
Publicado 2021
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680“…Then, a dysregulated circRNA-associated ceRNA network was constructed using the established multistep screening strategy. …”
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