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Mostrando 301 - 320 Resultados de 10,542 Para Buscar 'mapacho~', tiempo de consulta: 2.89s Limitar resultados
  1. 301
    “…METHODS: To determine whether the disease expression was influenced by the genetic ancestry of CDK cases in native Mapuche of the northwest area of Patagonia in Argentina, we examined mitochondrial DNA and Y-chromosome variation in 53 unrelated individuals. …”
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    Genetic Background and Climatic Droplet Keratopathy Incidence in a Mapuche Population from Argentina
  2. 302
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    Correction: Endogenous Retrovirus EAV-HP Linked to Blue Egg Phenotype in Mapuche Fowl
  3. 303
    Publicado 2014
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    Correction: Endogenous Retrovirus EAV-HP Linked to Blue Egg Phenotype in Mapuche Fowl
  4. 304
    “…Here we present annotation and variant discovery from high-quality complete genome sequences of a cohort of 11 Mapuche-Huilliche individuals (HUI) from Southern Chile. …”
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    Whole Genome Sequence, Variant Discovery and Annotation in Mapuche-Huilliche Native South Americans
  5. 305
    “…We predict that, in average, HAPV is 4.3 cm higher in European than in Mapuche adolescents (P = 0.042), and APV is 0.73 years later in European compared with Mapuche adolescents (P = 0.023). …”
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    Novel loci and Mapuche genetic ancestry are associated with pubertal growth traits in Chilean boys
  6. 306
    “…The Araucanía region of Chile is characterized by a significant rural Indigenous population—the Mapuche people—who preserve their cultural beliefs about the world around them. …”
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    The Commoditization of Ecosystems within Chile’s Mapuche Territory: A Violation of the Human Right to Health
  7. 307
    por Parra Camacho, Miguel Angel
    Publicado 2001
    Tesis Libro
    "Planeación y programación de la infraestructura física educativa"/cMiguel Angel Parra Camacho.
  8. 308
    por Watermann, Patrick, Dringen, Ralf
    Publicado 2023
    “…Cultured astrocytes that had been exposed to β-lapachone in concentrations of up to 3 µM remained viable and showed an almost linear extracellular accumulation of WST1 formazan for the first 60 min, while higher concentrations of β-lapachone caused oxidative stress and impaired cell metabolism. β-lapachone-mediated WST1 reduction was inhibited by the NQO1 inhibitors ES936 and dicoumarol in a concentration-dependent manner, with half-maximal inhibition observed at inhibitor concentrations of about 0.3 µM. β-lapachone-mediated WST1 reduction depended strongly on glucose availability, while mitochondrial substrates such as lactate, pyruvate or ketone bodies allowed only residual β-lapachone-mediated WST1 reduction. …”
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    β-lapachone-mediated WST1 Reduction as Indicator for the Cytosolic Redox Metabolism of Cultured Primary Astrocytes
  9. 309
    “…BACKGROUND: β-Lapachone has antitumor and wound healing-promoting activities. …”
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    β-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryos
  10. 310
    “…RESULTS: Here, we report that reducing NADPH pools by genetically or pharmacologically (bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES) or CB-839) inhibiting glutamine metabolism in mutant Kirsten rat sarcoma viral oncogene homolog (KRAS) PDA sensitizes cell lines and tumors to ß-lapachone (ß-lap, clinical form ARQ761). ß-Lap is an NADPH:quinone oxidoreductase (NQO1)-bioactivatable drug that leads to NADPH depletion through high levels of reactive oxygen species (ROS) from the futile redox cycling of the drug and subsequently nicotinamide adenine dinucleotide (NAD)+ depletion through poly(ADP ribose) polymerase (PARP) hyperactivation. …”
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    Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone
  11. 311
    por de la Torre, Daniel
    Publicado 2010
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    Relative Yield Loss Calculations in Wheat (Triticum durum Desf. cv. Camacho) due to Ozone Exposure
  12. 312
    por Li, Xin, Jia, Xiaoqian, Niu, Hu
    Publicado 2018
    “…PURPOSE: Herein, in our study, nanostructured lipid carrier (NLC) co-delivering β-lapachone (Lapa) and doxorubicin (DOX) was developed (LDNLC) with the aim to overcome the multidrug resistance (MDR) in breast cancer therapy. …”
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    Nanostructured lipid carriers co-delivering lapachone and doxorubicin for overcoming multidrug resistance in breast cancer therapy
  13. 313
    “…In this study, we aimed to design a highly swellable and mechanically robust matrix tablet (SMT) as a gastroretentive drug-delivery system (GRDDS) capable of improving the dissolution behavior of β-lapachone with low aqueous solubility. For the preparation of SMTs, the cogrinding technique and freeze–thaw method were used to disperse β-lapachone in SMTs in an amorphous state and to enhance the swelling and mechanical properties of SMTs, respectively. …”
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    Mechanically Robust Gastroretentive Drug-Delivery Systems Capable of Controlling Dissolution Behaviors of Coground β-Lapachone
  14. 314
    “…The mol­ecular conformation shows little difference with other lapachol derivatives and lapachol itself. The packing is directed by inter­molecular π–π and C—H⋯O inter­actions, as described by Hirshfeld surface analysis. …”
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    Crystal structure and Hirshfeld surface analysis of lapachol acetate 80 years after its first synthesis
  15. 315
    “…Our group has characterised the trypanocidal effect of naphthoquinones and their derivatives, with naphthoimidazoles derived from β-lapachone (N1, N2 and N3) being the most active in vitro. …”
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    Antiparasitic and anti-inflammatory activities of ß-lapachone-derived naphthoimidazoles in experimental acute Trypanosoma cruzi infection
  16. 316
    “…The elucidation of the complexation of lapachol and its derivatives to Fe(2+) cation has been done using the density functional theory (DFT). …”
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    Antioxidant Properties of Lapachol and Its Derivatives and Their Ability to Chelate Iron (II) Cation: DFT and QTAIM Studies
  17. 317
    “…Subsequently, β-Lapachone enhanced ROS levels by overexpressing NQO1, resulting in the transformation of BDOX into DOX. …”
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    Ultrasound Combined with Core Cross-Linked Nanosystem for Enhancing Penetration of Doxorubicin Prodrug/Beta-Lapachone into Tumors
  18. 318
    Libro
    Obra completa
  19. 319
    por Mañach, Jorge, 1898-1961
    Publicado 1933
    Libro
    Martí : el apóstol
  20. 320
    por Camacho Cardona, Mario
    Publicado 1998
    Libro
    Diccionario de arquitectura y urbanismo
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