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Mostrando 501 - 520 Resultados de 10,542 Para Buscar 'mapacho~', tiempo de consulta: 2.74s Limitar resultados
  1. 501
    por Gómez Vargas, Teresa Mariely
    Publicado 2008
    Tesis Libro
    Prevalencia de Gingivitis en pacientes embarazadas del Centro de Salud Manuel Ávila Camacho de Poza Rica, Ver. : Periodo Agosto 2007 - Enero 2008 /
  2. 502
    “…In this work, the synthesis, characterization and photophysical assays of a new trans-A(2)B-corrole derivative from the naturally occurring quinone are described. β-Lapachone is a naturally occurring quinoidal compound that provides highly fluorescent heterocyclic compounds such as lapimidazoles. …”
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    First report of trans-A(2)B-corrole derived from a lapachone derivative: photophysical, TD-DFT and photobiological assays
  3. 503
    “…β-lapachone, a major component in an ethanol extract of Tabebuia avellanedae bark, is a promising potential therapeutic drug for various tumors, including lung cancer, the leading cause of cancer-related deaths worldwide. …”
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    Sulindac Compounds Facilitate the Cytotoxicity of β-Lapachone by Up-Regulation of NAD(P)H Quinone Oxidoreductase in Human Lung Cancer Cells
  4. 504
    “…In this study, we investigated the effects of β-lapachone on the induction of apoptosis in human gastric carcinoma AGS cells. β-lapachone significantly inhibited cellular proliferation, and some typical apoptotic characteristics such as chromatin condensation and an increase in the population of sub-G1 hypodiploid cells were observed in β-lapachone-treated AGS cells. …”
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    β-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt Pathway
  5. 505
    “…The NAD(P)H:Quinone Oxidoreductase 1 (NQO1) bioactivatable drug, ß-lapachone (ARQ761 in clinical form), can provide tumor-selective and enhanced synergy with BER inhibition. ß-Lapachone undergoes NQO1-dependent futile redox cycling, generating massive intracellular hydrogen peroxide levels and oxidative DNA lesions that stimulate poly(ADP-ribose) polymerase 1 (PARP1) hyperactivation. …”
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    Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone
  6. 506
    “…Reducing NAD(+) pools by inhibiting NAMPT primed pancreatic ductal adenocarcinoma (PDA) cells for poly(ADP ribose) polymerase (PARP1)-dependent cell death induced by the targeted cancer therapeutic, β-lapachone (β-lap, ARQ761), independent of poly(ADP ribose) (PAR) accumulation. β-Lap is bioactivated by NADPH:quinone oxidoreductase 1 (NQO1) in a futile redox cycle that consumes oxygen and generates high levels of reactive oxygen species (ROS) that cause extensive DNA damage and rapid PARP1-mediated NAD(+) consumption. …”
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    NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone
  7. 507
    “…Huntington’s disease (HD) is one of the most devastating genetic neurodegenerative disorders with no effective medical therapy. β-Lapachone (βL) is a natural compound obtained from the bark of the Lapacho tree and has been reported to have beneficial effects on various diseases. …”
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    Amelioration of Huntington's disease phenotypes by Beta-Lapachone is associated with increases in Sirt1 expression, CREB phosphorylation and PGC-1α deacetylation
  8. 508
    “…BACKGROUND: NAD(P)H:quinone oxidoreductase 1 (NQO1) is a two-electron oxidoreductase expressed in multiple tumour types. ARQ 761 is a β-lapachone (β-lap) analogue that exploits the unique elevation of NQO1 found in solid tumours to cause tumour-specific cell death. …”
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    Phase 1 study of ARQ 761, a β-lapachone analogue that promotes NQO1-mediated programmed cancer cell necrosis
  9. 509
    “…OBJECTIVE(S): β-LAPachone (B-LAP) is a natural product with established anti-inflammatory properties. …”
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    β-LAPachone is renoprotective in streptozotocin-induced diabetic mice via regulating the PI3K/Akt/mTOR signaling pathway
  10. 510
    “…Administration of β-Lapachone significantly inhibited tumor growth and prolonged survival in a mouse xenograft model in vivo. …”
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    β-Lapachone Selectively Kills Hepatocellular Carcinoma Cells by Targeting NQO1 to Induce Extensive DNA Damage and PARP1 Hyperactivation
  11. 511
    “…IL6 secretion from immortalized BMSC (iBMSC) was directly regulated by NB cells and is involved in promoting the proliferation and metastasis of NB cells. Beta-Lapachone (ARQ-501, LPC), an ortho-naphthoquinone natural product, significantly prevented the iBMSC-induced malignant transformation effect on NB cells through suppressing the expression and secretion of IL6 from iBMSC in vitro and in vivo. …”
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    Beta-Lapachone Attenuates BMSC-Mediated Neuroblastoma Malignant Transformation by Inhibiting Gal-3/Gal-3BP/IL6 Axis
  12. 512
    Libro
    La tragédie de l'homme : poeme dramatique
  13. 513
    por Zollner, Linda, Boekstegers, Felix, Barahona Ponce, Carol, Scherer, Dominique, Marcelain, Katherine, Gárate-Calderón, Valentina, Waldenberger, Melanie, Morales, Erik, Rojas, Armando, Munoz, César, Retamales, Javier, De Toro, Gonzalo, Kortmann, Allan Vera, Barajas, Olga, Rivera, María Teresa, Cortés, Analía, Loader, Denisse, Saavedra, Javiera, Gutiérrez, Lorena, Ortega, Alejandro, Bertrán, Maria Enriqueta, Bartolotti, Leonardo, Gabler, Fernando, Campos, Mónica, Alvarado, Juan, Moisán, Fabricio, Spencer, Loreto, Nervi, Bruno, Carvajal, Daniel, Losada, Héctor, Almau, Mauricio, Fernández, Plinio, Olloquequi, Jordi, Carter, Alice R., Miquel Poblete, Juan Francisco, Bustos, Bernabe Ignacio, Fuentes Guajardo, Macarena, Gonzalez-Jose, Rolando, Bortolini, Maria Cátira, Acuña-Alonzo, Victor, Gallo, Carla, Ruiz Linares, Andres, Rothhammer, Francisco, Lorenzo Bermejo, Justo
    Publicado 2023
    “…SIMPLE SUMMARY: An association between individual levels of indigenous Chilean Mapuche ancestry and the risk of gallbladder cancer has been reported in observational studies, and the current program for gallbladder prevention in Chile takes the number of Mapuche surnames into account for prophylactic cholecystectomy. …”
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    Gallbladder Cancer Risk and Indigenous South American Mapuche Ancestry: Instrumental Variable Analysis Using Ancestry-Informative Markers
  14. 514
    “…Individual-data results and extensive sensitivity analyses confirmed the association between Mapuche ancestry and gallbladder cancer. Increasing Mapuche proportions were also associated with an increased mortality due to asthma and, interestingly, with a decreased mortality by diabetes. …”
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    Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile
  15. 515
    “…It shows that inmates with a university degree were taller than the rest; that those born legitimate were taller in adulthood; that those (Chilean born) whose surnames were Northern European were also taller than the rest, and in particular than those with Mapuche background; and that those able to read and write were also taller than illiterate inmates. …”
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    Height of Male Prisoners in Santiago de Chile during the Nitrate Era: The Penalty of being Unskilled, Illiterate, Illegitimate and Mapuche
  16. 516
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    Author Correction: Proton range verification with MACACO II Compton camera enhanced by a neural network for event selection
  17. 517
    por Kuri Camacho, Ramón
    Publicado 2001
    Libro
    Tres pensadores mexicanos : cultura católica e identidad nacional
  18. 518
    por Camacho Rivera, Francisco
    Publicado 2007
    Tesis Libro
    TEBOA :Tutor electrónico basado en objetos de aprendizaje
  19. 519
    Publicado 2001
    Libro
    Diálogos nacionales : ¿es posible un pacto nacional? /
  20. 520
    por Hamsun, Knut, 1859-1952
    Publicado 1959
    Libro
    En el pais de los cuentos
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