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  1. 7861
    “…[Image: see text] A commercially available ruthenium(II) PNP-type pincer catalyst (Ru-Macho) promotes the formation of α-chiral tert-butanesulfinylamines from racemic secondary alcohols and Ellman’s chiral tert-butanesulfinamide via a hydrogen borrowing strategy. …”
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    From Racemic Alcohols to Enantiopure Amines: Ru-Catalyzed Diastereoselective Amination
  2. 7862
    “…DADApy is freely available under the open-source Apache 2.0 license.…”
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    DADApy: Distance-based analysis of data-manifolds in Python
  3. 7863
    “…The pdb-tools are implemented in Python, without any external dependencies, and are freely available under the open-source Apache License at https://github.com/haddocking/pdb-tools/ and on PyPI.…”
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    pdb-tools: a swiss army knife for molecular structures
  4. 7864
    “…Moreover, we confirmed that the increase of cellular NAD(+) by NQO1 enzymatic action using the substrate β-Lapachone suppressed caerulein-induced AP with down-regulating TLR4-mediated inflammasome signalling, and thereby reducing the inflammatory responses and pancreatic cell death. …”
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    NAD(+) augmentation ameliorates acute pancreatitis through regulation of inflammasome signalling
  5. 7865
    “…RESULTS: One hundred sixteen patients were included, 58 with EA and 58 controls without EA, where matching was performed on age and APACHE-II score. The median age was 66 (Q1–Q3, 57–75) and median APACHE II score was 18 (Q1–Q3, 13–22). …”
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    Association of Epileptiform Activity With Outcomes in Toxic-Metabolic Encephalopathy
  6. 7866
    por Wang, Chengli, Ma, Li, Zhang, Wei
    Publicado 2023
    “…At admission, the JAAM, ISTH, CDSS, CRUSADE, and APACHE II scores were independently linked with SIC patients’ prognosis (all p < 0.05) in a multivariate logistic regression analysis. …”
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    Comparison of the prognostic value of four different critical illness scores in patients with sepsis-induced coagulopathy
  7. 7867
    “…Delta nCD64 (nCD64 T48 – nCD64 T0), %delta nCD64 [(nCD64 T48 – nCD64 T0)/nCD64 T0 x 100%], APACHE II and SOFA scores were calculated and examined. …”
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    Neutrophil CD64–a prognostic marker of sepsis in intensive care unit: a prospective cohort study
  8. 7868
    “…The areas under the ROC curve (AUC) for APACHE II score, Gal-3-T72, and BNP-T72 were 0.687, 0.799, and 0.723, respectively. …”
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    Serum Galectin-3 Predicts Mortality in Venoarterial Extracorporeal Membrane Oxygenation Patients
  9. 7869
    “…However, their prognosis was equivalent to that of the other ICU patients. ARDS, APACHE II and McCabe scores were independent predictors of evolution to chronicity.…”
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    The distinct clinical profile of chronically critically ill patients: a cohort study
  10. 7870
    “…Glycaemia in patients with high BMI and APACHE II scores may be more difficult to control using intensive insulin therapy protocols. …”
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    Tight glycaemic control: a prospective observational study of a computerised decision-supported intensive insulin therapy protocol
  11. 7871
    “…Severity of illness scores and mortality prediction models were compared (UK Acute Physiology and Chronic Health Evaluation [APACHE] II, Stuivenberg Hospital Acute Renal Failure [SHARF] T0, SHARF II0 and the Mehta model). …”
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    Case mix, outcome and activity for patients with severe acute kidney injury during the first 24 hours after admission to an adult, general critical care unit: application of predictive models from a secondary analysis of the ICNARC Case Mix Programme Database
  12. 7872
    “…The Acute Physiology and Chronic Health Evaluation (APACHE) II score, Simplified Acute Physiology Score (SAPS) II and ICNARC score were evaluated for discrimination (the ability to distinguish survivors from nonsurvivors); and the APACHE II, SAPS II and ICNARC mortality probabilities were evaluated for calibration (the accuracy of the estimated probability of survival). …”
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    Admission factors associated with hospital mortality in patients with haematological malignancy admitted to UK adult, general critical care units: a secondary analysis of the ICNARC Case Mix Programme Database
  13. 7873
    “…Independent predictive factors for mortality were low-muscle area, sex, and APACHE II score, whereas BMI and admission diagnosis were not. …”
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    Low skeletal muscle area is a risk factor for mortality in mechanically ventilated critically ill patients
  14. 7874
    “…The temperature categories (≤35.5°C, 35.6–36.5°C, 36.6–37.5°C, 37.6–38.5°C, 38.6–39.5°C, ≥39.6°C) were based on the temperature data of the Acute Physiology and Chronic Health Evaluation II (APACHE II) scoring. We compared patient characteristics, physiological data, and mortality between groups. …”
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    The impact of body temperature abnormalities on the disease severity and outcome in patients with severe sepsis: an analysis from a multicenter, prospective survey of severe sepsis
  15. 7875
    “…Th17/Treg ratio was positively correlated with APACHE II score, SOFA score, and Lung Injury Score, while negatively correlated with PaO(2)/FiO(2). …”
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    The ratio of Th17/Treg cells as a risk indicator in early acute respiratory distress syndrome
  16. 7876
    “…Aggregation correlated inversely with SOFA and APACHE II scores (n = 34; p < 0.05). Thr855 phosphorylation of MYPT from unstimulated platelets was not decreased in patients with septic shock (n = 22 to 24). …”
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    Attenuated platelet aggregation in patients with septic shock is independent from the activity state of myosin light chain phosphorylation or a reduction in Rho kinase-dependent inhibition of myosin light chain phosphatase
  17. 7877
    “…The plasma levels of the biomarkers were measured and the APACHE II and SOFA scores were calculated within 24 hours of patient enrollment into our study. …”
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    The Cold-Inducible RNA-Binding Protein (CIRP) Level in Peripheral Blood Predicts Sepsis Outcome
  18. 7878
    “…The optimal cutoff values were risk class 3.5 for RESP and 35.5 for APACHE II score, and both showed 70.0% sensitivity and 84.6% specificity. …”
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    Performance of Multiple Risk Assessment Tools to Predict Mortality for Adult Respiratory Distress Syndrome with Extracorporeal Membrane Oxygenation Therapy: An External Validation Study Based on Chinese Single-center Data
  19. 7879
    “…We also examined admission Acute Physiology and Chronic Health Evaluation (APACHE) II score, haloperidol use, and days of benzodiazepine use in post hoc analyses. …”
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    Antipsychotic prescribing patterns during and after critical illness: a prospective cohort study
  20. 7880
    “…Logistic and linear regression analyses were used for other clinical outcomes. RESULTS: Mean APACHE II score was 24 ± 8 and 6-month mortality was 35.6%. …”
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    Skeletal muscle quality as assessed by CT-derived skeletal muscle density is associated with 6-month mortality in mechanically ventilated critically ill patients
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