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  1. 9941
    “…PATIENTS AND METHODS: A total of 136 ALI patients were divided into survival (n = 86) and death groups (n = 50), or into low/middle‐risk (n = 77) and high‐risk groups (n = 59) according to APACHE II scores. Bioinformatics was used to explore the mechanism of action of miR‐21‐3p in humans. …”
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    Prognostic value of pulmonary ultrasound score combined with plasma miR‐21‐3p expression in patients with acute lung injury
  2. 9942
    por Huang, Xue, Wang, Nan, Duanmu, Ningjie, Fu, Li
    Publicado 2022
    “…The early warning accuracy of the proposed ANGA + RF mathematical model was higher than 95% in contrast to that of the APACHE-II score and the SOFA score. Compared with patients in the severe group, the MRSA infection rate and the levels of procalcitonin (PCT), C-reactive protein (CRP), and activated partial thromboplastin time (APTT) of SA sepsis-lung injury patients were greatly reduced, while thrombin time (TT) and D-D dimer in the death group were considerably increased (p < 0.05), and the PLT level was greatly reduced (p < 0.05). …”
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    Early Warning and Clinical Epidemiological Characteristics of Lung Injury in the Treatment of Infectious Staphylococcus aureus Sepsis by Vancomycin Based on Adaptive Niche Genetic Algorithm and Pulmonary Ultrasound Images
  3. 9943
    “…Based on the optimal cut-off of t‐PAIC = 17.9 ng/mL, we found that patients at or above this threshold had significantly higher lactate levels and scores on the Acute Physiology and Chronic Health Evaluation II (APACHE II) and Sequential Organ Failure Assessment (SOFA). …”
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    Tissue-Type Plasminogen Activator-Inhibitor Complex as an Early Predictor of Septic Shock: A Retrospective, Single-Center Study
  4. 9944
    por Huang, Qinghe, Wang, Yibin, He, Fuyun
    Publicado 2022
    “…Moreover, lnc‐ITSN1‐2 had a positive connection with C‐reactive protein (p = 0.001), acute pathologic and chronic health evaluation (APACHE) II (p = 0.024), and sequential organ failure assessment (SOFA) scores (p = 0.022). …”
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    Blood long non‐coding RNA intersectin 1–2 is highly expressed and links with increased Th17 cells, inflammation, multiple organ dysfunction, and mortality risk in sepsis patients
  5. 9945
    “…RESULTS: In older adults, sepsis, malnutrition, antibiotic prescription and severity (APACHE and SOFA scores) were higher than in the group under 60 years of age. …”
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    Gut microbiota alterations in critically ill older patients: a multicenter study
  6. 9946
    “…The aims of the present study were to investigate whether there was a correlation between brain and subcutaneous glycerol levels and whether the ratio of interstitial glycerol in the brain and subcutaneous tissue (glycerol(brain/sc)) was associated with tissue damage in the brain, measured by using the Rotterdam score, S-100B, neuron-specific enolase (NSE), the Injury Severity Score (ISS), the Acute Physiology and Chronic Health Evaluation Score (APACHE II), and trauma type. A potential association with clinical outcome was explored. …”
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    Correlation of Cerebral and Subcutaneous Glycerol in Severe Traumatic Brain Injury and Association with Tissue Damage
  7. 9947
    “…Factors associated with CAPA included old age (68 years vs. 62, p = .033), active smoking (17.9% vs. 1.8%, p = .014), chronic respiratory diseases (48.1% vs. 26.3%, p = .043), chronic renal failure (25.0% vs. 3.6%, p = .005), chronic corticosteroid treatment (28.6% vs. 1.8%, p < .001), tocilizumab therapy (92.9% vs. 66.1%, p = .008) and high APACHE II at ICU admission (median 13 vs. 10 points, p = .026). …”
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    COVID‐19‐associated pulmonary aspergillosis (CAPA): Risk factors and development of a predictive score for critically ill COVID‐19 patients
  8. 9948
    “…METHODS AND MATERIALS: For all patients admitted in a medical ICU, baseline data (demographic, APACHE II, length of ICU stay, and days of mechanical ventilation) were noted. …”
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    Medication Prescription Errors in the Intensive Care Unit: Prospective Observational Study
  9. 9949
    “…VWB supports programming languages such as Python, Spark, SQL and R for in-depth analysis in Apache Zeppelin notebooks. In addition to variant calls and phenotypic information, VWB hosts rich external variant annotations in the public domain, such as Cancer Hotspots, COSMIC and ClinVar. …”
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    OTHR-45. Kids First Variant WorkBench: application to germline genomic discoveries in the Children's Brain Tumor Network
  10. 9950
    “…METHODS: We conducted a multicentre, double-blind, randomised, placebo-controlled trial involving ANP patients with an Acute Physiology and Chronic Health Evaluation II (APACHE II) score ≥ 8 and a computed tomography (CT) severity score ≥ 5 admitted within 7 days of the advent of symptoms. …”
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    Immune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial
  11. 9951
    “…Logistic regression analysis adjusted for sex, age, education status, and Acute Physiology and Chronic Health Evaluation II (APACHE II) scores showed that pre-admission functional status as assessed by the SF-12 MCS (odds ratio [OR]: 14,2; 95% confidence interval [CI]: 2.5-79.0), SF-12 PCS (OR: 10.6; 95% CI: 1.8-62.7), and EQ-5D-5L (OR: 8.0; 95% CI: 1.5-44.5) were found to be independently associated with mortality. …”
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    Worse pre-admission quality of life is a strong predictor of mortality in critically ill patients
  12. 9952
    “…We observed a significant decrease in the use of deoxycholate amphotericin B (47.4%, 14.8% and 11.9%), and an increase in the use of echinocandins (0%, 2.8% and 49.1%; p < 0.001). The APACHE II score increased over time (median 16, 17.5, and 22, p < 0.001). …”
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    Secular trends of candidemia at a Brazilian tertiary care teaching hospital
  13. 9953
    “…Male sex (aOR: 5.8, 95% CI 1.55-21.42; p < 0.01), APACHE II score (aOR: 1.17, 95% CI 1.06-1.30; p < 0.01) and the corrected anion gap (aOR: 1.14, 95% CI 1.02-1.27; p = 0.02) were identified as predictors of in-hospital death using multivariable logistic regression. …”
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    The frequency of acid-base disorders on admission to the intensive care and its association with in-hospital outcome, Cape Town, South Africa: a retrospective cohort study
  14. 9954
    “…RESULTS: A total of 28,200 patients were enrolled with a median age of 71 years (interquartile range [IQR], 59 to 80). The median APACHE II score was 18 (IQR, 13 to 24) with no significant difference between patients admitted during off-hours and those admitted during office-hours. …”
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    Association between ICU admission during off-hours and in-hospital mortality: a multicenter registry in Japan
  15. 9955
    “…Independent risk factors for AKI in ARDS patients were age (OR 1.027, 95% CI 1.009–1.045), a history of diabetes mellitus (OR 2.110, 95%CI 1.100–4.046) and chronic kidney disease (CKD) (OR 9.328, 95%CI 2.393–36.363), APACHE II score (OR 1.049, 95%CI 1.008–1.092), average lactate level in the first 3 days (OR 1.965, 95%CI 1.287–3.020) and using ECMO support (OR 2.359, 95%CI 1.154–4.824). …”
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    Clinical characteristics of new-onset acute kidney injury in patients with established acute respiratory distress syndrome: A prospective single-center post hoc observational study
  16. 9956
    “…Mean RALE scores increased from 28 (22–37) at baseline to 35 (26–42) (p < 0.001) on D1 of ECMO; increasing RALE was associated with higher baseline APACHE III scores [ß value +0.19 (0.08, 0.30) p = 0.001], and greater reductions in tidal volume [ß value −2.08 (−3.07, −1.10) p < 0.001] after ECMO initiation. …”
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    The impact of reduction in intensity of mechanical ventilation upon venovenous ECMO initiation on radiographically assessed lung edema scores: A retrospective observational study
  17. 9957
    “…There were no differences in age or APACHE‐III scores between the two groups. Overall, 36.0% (318/884) had treatment limitations, but similar between the two groups (35.8% [132/369] vs 36.1% [186/515]; p = 0.92). …”
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    Treatment limitations and clinical outcomes in critically ill frail patients with and without COVID‐19 pneumonitis
  18. 9958
    “…At 12 months, 52/110 (47%) patients had PICS, which was associated with prolonged duration of rehabilitation, higher APACHE scores, and higher mRS and CPC scores at hospital discharge. …”
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    Post-intensive care syndrome in out-of-hospital cardiac arrest patients: A prospective observational cohort study
  19. 9959
    “…Significantly, reasons for incomplete stone removal at once were large stone (>10 mm) (P < 0.001) and higher acute physiology and chronic health evaluation scoring system (APACHE-II) (P = 0.005). CONCLUSIONS: ERCP was recommended with caution in patients ≥ 85 years of age with ABP or higher CCI undergoing endoscopic biliary stone removal. …”
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    Risk factors for complications in elderly patients aged 85 years and over undergoing endoscopic biliary stone removal
  20. 9960
    “…In validation stage II, the SSBD results were obtained in 4 hr, leading to better APACHE II scores (p=0.0035, ANOVA test). Based on the results acquired by SSBD, cultivation results could deviate from the real pathogenic situation with polymicrobial infections. …”
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    Novel fast pathogen diagnosis method for severe pneumonia patients in the intensive care unit: randomized clinical trial
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