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  1. 10161
    “…B10 or CD19(+)CD24(hi)CD27(hi) cells were negatively correlated with the severity index (APACHE II score), inflammatory markers (C-reactive protein, CD64 index), and cytokines (IL-6, IL-17, TNF-α). …”
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    Decreased levels of regulatory B cells in patients with acute pancreatitis: association with the severity of the disease
  2. 10162
    “…Downregulation of miR-23a-3p was significantly negatively correlated with risk scores of GRACE (Global Registry of Acute Coronary Events) and APACHE II (Acute Physiology and Chronic Health Evaluation II). …”
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    Value of Serum miR-23a, miR-30d, and miR-146a Biomarkers in ST-Elevation Myocardial Infarction
  3. 10163
    “…In a binary logistic regression model, age, male sex, APACHE III score, and premorbid psychiatric disorder (OR 1.8, CI 1.1–3.0; p=0.023) were all independently associated with the presence of delirium. …”
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    Impact of a Premorbid Psychiatric Disorder on the Incidence of Delirium during ICU Stay, Morbidity, and Long-Term Mortality
  4. 10164
    “…Patients with PaO(2)/F(I)O(2) ≤ 240 had a lower APACHE-II score at ICU admission; however, at pneumonia onset they had higher CPIS, SOFA score, acute respiratory distress syndrome criteria and incidence of shock, and less microbiological confirmation of pneumonia (117, 69% vs. 71, 85%, p = 0.008), compared to patients with PaO(2)/FIO(2) > 240. …”
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    Ventilator-Associated Pneumonia and PaO(2)/F(I)O(2) Diagnostic Accuracy: Changing the Paradigm?
  5. 10165
    “…Temperature amplitude in groups B and C upon entry was negatively correlated with SAPS II (r = − 0.72 and − 0.84, p < 0.003) and APACHE II scores (r = − 0.70 and − 0.63, p < 0.003), respectively, as well as duration of ICU and hospital stay in group B (r = − 0.62 and − 0.64, p < 0.003) and entry SOFA score in group C (r = − 0.82, p < 0.003). …”
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    Determining rhythmicity and determinism of temperature curves in septic and non-septic critically ill patients through chronobiological and recurrence quantification analysis: a pilot study
  6. 10166
    “…There were no significant differences in age, sex, APACHE II score, or admission diagnosis. POCUS group used fewer resources per patient in the first 5 days of hospitalization: chest radiography (2.6 ± 2.0 vs 4.1 ± 3.5, P = 0.01), additional ultrasound evaluations performed by a radiology specialist (0.6 ± 0.7 vs 1.1 ± 0.7, P = 0.002), and computed tomography studies (0.5 ± 0.6 vs 0.9 ± 0.7, P = 0.007). …”
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    Impact of an ultrasound-driven diagnostic protocol at early intensive-care stay: a randomized-controlled trial
  7. 10167
    “…The mean of Acute Physiology and Chronic Health Evaluation (APACHE) II scores at intensive care unit (ICU) admission was 21.7 ± 8.3 (range 11–37). …”
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    Rescue fecal microbiota transplantation for antibiotic-associated diarrhea in critically ill patients
  8. 10168
    “…The median age was 49 (35–58) years, 50% were female and 93.3% were Caucasian. Median APACHE II score was 9 (5–12). Persons who inject drugs (PWID) comprised 50%. …”
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    200. Real-World Experience with Dalbavancin for Complicated Gram-Positive Infections: A Multicenter Evaluation
  9. 10169
    “…We evaluated primary outcomes of gross days of antimicrobial use, percent of antibiotic-free days and days of individual antimicrobial use, adjusted for APACHE scores and ECMO duration. RESULTS: When adjusted for days on ECMO, mean antibiotic days decreased after implementation of the protocol; for vancomycin (0.27 vs. 0.02, P < 0.0003), cefepime (0.15 vs. 0.02, P < 0.02), meropenem (0.09 vs. 0, P < 0.02), zosyn (0.16 vs. 0, P < 0.002), caspofungin (0.346, 0.138 P < 0.003). …”
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    1077. Reduce Anti-Microbial Use in Extracorporeal Membrane Oxygenation: Reduce AMMO Study
  10. 10170
    “…Q1 ICUs, adjusted by APACHE II score (OR, 2.332; 95% CI: 1.463–3.717; p < 0.001) or SSI score (OR, 2.445; 95% CI: 1.468–4.074; p = 0.001). …”
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    ICU Physicians' Perception of Patients' Tolerance Levels in Light Sedation Impacts Sedation Practice for Mechanically Ventilated Patients
  11. 10171
    “…This study aimed to identify suitable blood biomarker (MR-proADM, PCT, CRP and lactate) or clinical score (SOFA and APACHE II) combinations to address this unmet clinical need. …”
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    Biomarkers and clinical scores to aid the identification of disease severity and intensive care requirement following activation of an in-hospital sepsis code
  12. 10172
    por Tam, Catherine WY, Shum, HP, Yan, WW
    Publicado 2019
    “…Logistic regression analysis identified the following independent predictors of poor outcome (GOS 1–3 at 3 months): age >55 years old, acute physiology and chronic health evaluation IV (APACHE IV) score >50, World Federation of Neurosurgical Societies (WFNS) grade >3, Fisher grade >2, presence of intracranial hemorrhage (ICH)/intraventricular hemorrhage (IVH), use of mannitol, use of loop diuretic aneurysms, involving posterior circulation, and hypernatremia >146 mmol/L. …”
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    Impact of Dysnatremia and Dyskalemia on Prognosis in Patients with Aneurysmal Subarachnoid Hemorrhage: A Retrospective Study
  13. 10173
    “…Subgroup analysis will be carried out for patients with and without septic shock at presentation, and for patients whose initial APACHE II scores are > 20 versus ≤ 20. DISCUSSION: In addition to an estimate of the clinical effectiveness of an OA approach for SCIAS, an understanding of its cost effectiveness will be required prior to its adoption in any resource-constrained environment. …”
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    Protocol for a parallel economic evaluation of a trial comparing two surgical strategies in severe complicated intra-abdominal sepsis: the COOL-cost study
  14. 10174
    “…Receiver operating characteristic curve analysis showed that the plasma levels of IL-17 and IL-23 at 2 or 7 days post ROSC were able to predict the mortality of PCAS patients, and positively correlated with Acute Physiology and Chronic Health Evaluation (APACHE)-II score and time to ROSC. CONCLUSION: These results provide the first evidence that the elevated plasma IL-17 and IL-23 levels are associated with poor outcome in PCAS patients. …”
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    High plasma levels of pro-inflammatory factors interleukin-17 and interleukin-23 are associated with poor outcome of cardiac-arrest patients: a single center experience
  15. 10175
    “…The majority were male (60%), mechanically ventilated > 48 h (59.4%), mean age of 48 (+/− 16), mean acute physiology and chronic health evaluation II (APACHE II) at admission 9.4 (+/− 4.6), median length of stay 3 (2–28 days). …”
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    Post traumatic stress symptoms, anxiety, and depression in patients after intensive care unit discharge – a longitudinal cohort study from a LMIC tertiary care centre
  16. 10176
    “…Their median age was 66 years; 47 were males; 46 were critically ill with a median APACHE II score of 18 (2–32); and 91 received antibiotic treatment, mainly with carbapenems (56%), before being diagnosed with a S. maltophilia infection. …”
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    Stenotrophomonas maltophilia Infections: Clinical Characteristics and Factors Associated with Mortality of Hospitalized Patients
  17. 10177
    “…RESULTS: A total of 43 patients were included (G1 = 28 [65.1%]; G2 = 10 [23.3%] and G3 = 5 [11.6%]), with a mean age of 65 years (range: 52-72), 62% males, APACHE II 18 (15-24), SOFA 6 (4-7). Arterial hypertension (30.2%) and obesity (25.6%) were the most frequent comorbidities. …”
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    Infección grave por coronavirus SARS-CoV-2: experiencia en un hospital de tercer nivel con pacientes afectados por COVID-19 durante la pandemia 2020
  18. 10178
    “…RESULTS: Forty-two patients were recruited, median APACHE-II score was 23 [15–31] and 28-day mortality 23%. …”
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    Hypoxia-related parameters during septic shock resuscitation: Pathophysiological determinants and potential clinical implications
  19. 10179
    “…RESULTS: Among these patients, the median age was 28 years, median BMI 28 kg/m(2) median sequential organ failure assessment (SOFA) score 9, and median acute physiology and chronic health evaluation (APACHE) III score 74. All patients received lung-protective mechanical ventilation with high positive end-expiratory pressure and low plateau pressures. …”
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    Adenovirus-associated Acute Respiratory Distress Syndrome: Need for a Protocol-based Approach
  20. 10180
    “…In subgroup analysis, the ultrafiltration volume was lower in DNC than CBC group (1,932.26±749.39 DNC vs. 2,640.00±996.24 CBC, P=0.004), when ACC time less than or equal to 90 minutes. The apache score was better in DNC group (4.75±3.41, P=0.041), when ACC time greater than 90 min. …”
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    del Nido cardioplegia in surgery for aortic root disease: a historically controlled study
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