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  1. 10421
    “…More than 3 derailed parameters were associated with 100 % intervention (Mean 3.47, SD-1.23). High APACHE III score on admission (>40) was associated with increased intervention (p = 0.001). …”
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    Study of the occurrence of intra-abdominal hypertension and abdominal compartment syndrome in patients of blunt abdominal trauma and its correlation with the clinical outcome in the above patients
  2. 10422
    “…Obese patients (body mass index (BMI) ≥35 kg/m(2)) were matched with non-obese patients (BMI <30 kg/m(2)) based on renal function, age and acute physiology and chronic health evaluation (APACHE)-II score at admission. All patients in this study received a loading dose of 25 mg/kg then a maintenance dose based on renal function according to the protocol. …”
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    Daily vancomycin dose requirements as a continuous infusion in obese versus non-obese SICU patients
  3. 10423
    “…In 9 RCTs, with a total of 489 patients, Tα1 administered once per day decrease APACHE II score significantly (SMD −0.80, 95 % CI −1.14 to −0.47, p < 0.0001) while Tα1 twice per day showed no effect (SMD 0.30, 95 % CI-0.10 to 0.70, p = 0.14). …”
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    The efficacy of thymosin α1 as immunomodulatory treatment for sepsis: a systematic review of randomized controlled trials
  4. 10424
    “…Among medical patients, when corrected for age groups and APACHE-II scores, there were no statistically significant associations between baseline plasma levels and 6-month mortality, except for zinc (HR 1.06, 95% CI 1.00–1.12, P = 0.026). …”
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    Glutamine, fish oil and antioxidants in critical illness: MetaPlus trial post hoc safety analysis
  5. 10425
    “…A positive linear relationship existed between the levels of CD14(++)CD16(+) monocytes and the Acute Physiology and Chronic Health Evaluation (APACHE) II score as well as Sequential Organ Failure Assessment (SOFA) score. …”
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    Adipose-derived mesenchymal stem cells modulate CD14(++)CD16(+) expression on monocytes from sepsis patients in vitro via prostaglandin E2
  6. 10426
    “…RESULTS: Significantly more patients with than without diabetes were 65 years of age or older; patients with diabetes were also more likely to weigh ≥75 kg at baseline (57.1% vs 44.5%), to have renal impairment (48.5% vs 30.2%), or to have APACHE II scores ≥10 (33.8% vs 17.0%). More patients with diabetes had comorbidities and an increased incidence of complicating factors in both cIAI and cUTI. …”
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    Analysis of patients with diabetes and complicated intra-abdominal infection or complicated urinary tract infection in phase 3 trials of ceftolozane/tazobactam
  7. 10427
    por Iizuka, Yusuke, Sanui, Masamitsu, Sasabuchi, Yusuke, Lefor, Alan Kawarai, Hayakawa, Mineji, Saito, Shinjiro, Uchino, Shigehiko, Yamakawa, Kazuma, Kudo, Daisuke, Takimoto, Kohei, Mayumi, Toshihiko, Azuhata, Takeo, Ito, Fumihito, Yoshihiro, Shodai, Hayakawa, Katsura, Nakashima, Tsuyoshi, Ogura, Takayuki, Noda, Eiichiro, Nakamura, Yoshihiko, Sekine, Ryosuke, Yoshikawa, Yoshiaki, Sekino, Motohiro, Ueno, Keiko, Okuda, Yuko, Watanabe, Masayuki, Tampo, Akihito, Saito, Nobuyuki, Kitai, Yuya, Takahashi, Hiroki, Kobayashi, Iwao, Kondo, Yutaka, Matsunaga, Wataru, Nachi, Sho, Miike, Toru, Takahashi, Hiroshi, Takauji, Shuhei, Umakoshi, Kensuke, Todaka, Takafumi, Kodaira, Hiroshi, Andoh, Kohkichi, Kasai, Takehiko, Iwashita, Yoshiaki, Arai, Hideaki, Murata, Masato, Yamane, Masahiro, Shiga, Kazuhiro, Hori, Naoto
    Publicado 2017
    “…Patients who received IVIgG were more severely ill than those who did not (Acute Physiology and Chronic Health Evaluation (APACHE) II score 24.2 ± 8.8 vs 22.6 ± 8.7, p < 0.001). …”
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    Low-dose immunoglobulin G is not associated with mortality in patients with sepsis and septic shock
  8. 10428
    “…Acute Physiology and Chronic Health Evaluation (APACHE) IV, lactate, and glucose were associated with renal and liver dysfunction in multivariate analysis (p < 0.001), with a U-shaped relationship for glucose. …”
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    The association of early combined lactate and glucose levels with subsequent renal and liver dysfunction and hospital mortality in critically ill patients
  9. 10429
    “…However, PRG had a higher age at diagnosis (74 vs. 64 years, p = 0.037), a higher APACHE II score (12 vs. 7, p = 0.002), lower disease-free survival (p = 0.001), a higher recurrence rate (56.5 vs. 19%, p = 0.002), a higher distant metastasis rate (39.1 vs. 13.8%, p = 0.015), and a higher local recurrence rate (43.5 vs. 5.2%, p < 0.001) than did OBG. …”
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    Outcome of colon cancer initially presenting as colon perforation and obstruction
  10. 10430
    “…In multivariable analysis, APACHE II score (adjusted odds ratio [aOR] 1.13; 95% CI, 1.08–1.19, P < 0.001), coronary artery disease (CAD) (aOR 5.7; 95% CI, 1.2–27.8, P = 0.03), prior opportunistic infection (OI) (aOR 2.6; 95% CI, 1.2–5.6, P = 0.015) and duration of HIV infection (aOR 1.07 per year; 95% CI, 1.01–1.14, P = 0.025) were independently associated with DNR status. …”
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    What Determines Do-Not-Resuscitate Status in Critically Ill HIV Patients?
  11. 10431
    “…Patients with carbapenem-resistant VARI had significantly greater ICU costs than patients with carbapenem-susceptible isolates (6053 USD (IQR 3806–7824) vs 3131 USD (IQR 2108–7551), p = 0.04) and after correction for adequacy of initial antibiotics and APACHE II score, showed a trend towards increased risk of in-hospital death (HR 2.82, 95% CI 0.75–6.75, p = 0.15). …”
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    Ventilator-associated respiratory infection in a resource-restricted setting: impact and etiology
  12. 10432
    “…Charlson Comorbidity Index, Elixhauser Comorbidity Index, APACHE prognostic system), but also important studies on chronic diseases (e.g. epidemiology of mental disorders and its correlates by the U.S. …”
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    Mapping of global scientific research in comorbidity and multimorbidity: A cross-sectional analysis
  13. 10433
    “…Demographics, mechanical ventilation time, stay at intensive care unit, hospitalization period, time of first weaning, success of weaning, ventilator-related pneumonia (VRP), total doses of drugs, re-intubation frequency, Acute Physiology and Chronic Health Evaluation II (APACHE II), Sequential Organ Failure Assessment (SOFA) scores and mortality rates of patients were compared. …”
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    The Effect of Daily Sedation-Weaning Application on Morbidity and Mortality in Intensive Care Unit Patients
  14. 10434
    “…The main factors independently associated with increased mortality were (i) pre-MV factors: age, Apache II scores, heart failure (odds ratio [OR], 1.42; 95% confidence interval [CI], 0.54–3.73; P < 0.001); (ii) patient management factors: positive end-expiratory pressure (OR, 2.69; 95% CI, 0.84–8.61; P < 0.001); (iii) Factors occurring over the course of MV: PaO(2)/FiO(2) ratio < 100 (OR, 1.66; 95% CI, 0.67–4.11; P < 0.001) and development of renal failure (OR, 2.33; 95% CI, 2.05–2.42; P < 0.001) and hepatic failure (OR, 2.07; 95% CI, 1.91–2.24; P < 0.001) after initiation of MV. …”
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    Factors determining outcomes in adult patient undergoing mechanical ventilation: A “real-world” retrospective study in an Indian Intensive Care Unit
  15. 10435
    “…A Web-based survey system was developed using a Linux, Apache, MySQL, PHP stack solution. The Web survey was set up to include four questionnaires: the Chinese-version Fagerstrom Tolerance Questionnaire, the Chinese-version Alcohol Use Disorders Identification Test, the Betel Nut Dependency Scale, and a sociodemographic form with several chronic diseases. …”
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    Tobacco-Smoking, Alcohol-Drinking, and Betel-Quid-Chewing Behaviors: Development and Use of a Web-Based Survey System
  16. 10436
    “…The findings reflected that in comparison to single UTI, XBJ and UTI combination therapy could significantly lower 28-day mortality (RR = 0.54, 95% CI [0.39, 0.73], P < 0.0001), shorten duration of mechanical ventilation (SMD = −1.13, 95% CI [−1.30, −0.95], P < 0.00001), reduce length of ICU stay (SMD = −0.84, 95% CI [−1.00, −0.67], P < 0.00001), and decrease APACHE II score (SMD = −1.09, 95% CI [−1.49, −0.69], P < 0.00001). …”
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    Efficacy and Safety of Xuebijing Injection Combined With Ulinastatin as Adjunctive Therapy on Sepsis: A Systematic Review and Meta-Analysis
  17. 10437
    “…There was no significant difference between the two groups in baseline characteristics, including gender, age, underlying disease, comorbidities, APACHE II score, SOFA score, and PaO2/FiO2 ratio (P > 0.05). …”
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    Diagnostic value of cardiopulmonary ultrasound in elderly patients with acute respiratory distress syndrome
  18. 10438
    “…Data gathered on demographics, APACHE II, Charlson score, modified Child-Turcotte-Pugh classification (CTP), mortality at 6 weeks, re-bleeding within 7 days, readmissions (30 and 90 days), incidence of infections at admission and follow-up. …”
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    1582. Is Antibiotic Prophylaxis Needed for All Acute Variceal Bleeds in Decompensated Cirrhosis? A Retrospective Pilot Study
  19. 10439
    “…At baseline, Charlson’s co-morbidity and APACHE II scores were comparable. Initial antibiotic prescriptions were similar, and the majority were for respiratory (67.0% vs. 68.2%) or urinary (17% vs. 19.6%) infections. …”
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    186. Effective Antimicrobial StewaRdship StrategIES (ARIES): Cluster-Randomized Trial of a Clinical Decision Support System to Supplement Antibiotic Prospective Review and Feedback
  20. 10440
    “…Patients treated with HD were more likely to present with colitis (19.2 vs. 29.5%, P = 0.01) and have higher infection severity based on IDSA (P < 0.01), Zar (P < 0.01), and American College of Gastroenterology (P < 0.02) criteria. Modified APACHE II scores were similar between SD and HD groups (median: 12.2 vs. 12.9, P = 0.17). …”
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    1110. A multicenter Evaluation of Outcomes Associated With Oral Vancomycin Dose in Patients With Clostridium difficile Infection
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