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  1. 10501
    “…After matching on age (± 5 years), gender, septic shock, and Apache II score (± 4 points) when polymyxin B was started, 132 patients were included. 44 patients received simultaneous IH plus IV polymyxin B and 88 patients received IV polymyxin B. …”
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    Low-dose intravenous plus inhaled versus intravenous polymyxin B for the treatment of extensive drug-resistant Gram-negative ventilator-associated pneumonia in the critical illnesses: a multi-center matched case–control study
  2. 10502
    “…Logistic model results showed that age, SOFA score, APACHE II score, the number of multiple organ failure (MODS), intracranial infection, the increase of Pcv-aCO2, Pcv-aCO2/Ca-cvO2, and the increase of lactic acid were independent risk factors for death in patients with septic shock (OR values were 1.519, 1.808, 1.781, 1.912, 2.069, 1.848, 1.781, and 1.642, respectively, P < 0.05). …”
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    Relationship between Dynamic Changes of Microcirculation Flow, Tissue Perfusion Parameters, and Lactate Level and Mortality of Septic Shock in ICU
  3. 10503
    “…Conclusions In our study, the COVID-19 ARDS patients who required early invasive ventilatory support and in whom the physiological parameter was more severe (Acute Physiology and Chronic Health Evaluation II (APACHE II) and Sequential Organ Failure Assessment (SOFA) scores) had a better outcome than the late intubation group. …”
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    Clinical Outcomes of COVID-19-Induced Acute Respiratory Distress Syndrome in Patients With Three Different Respiratory Support Modalities: A Retrospective Cohort Study
  4. 10504
    “…RESULTS: The Acute Physiology and Chronic Health Evaluation II (APACHE II) score and Sequential Organ Failure Assessment (SOFA) score in the NRBC-positive group were higher (23.52 ± 9.39 vs. 19.62 ± 7.59; 13.50 (9.00–17.50) vs. 8.00 (6.00–12.00)). …”
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    Investigation of the Possible Causes of NRBC in ICU Patients and the Dynamic Trend of NRBC Count in Survival and Death Patients or with Different Underlying Diseases: A Retrospective Study
  5. 10505
    “…Serum sCD59 levels were positively correlated with serum sC5b-9, TNF-α, IL-6, NSE, S100β, SOFA score and APACHE II score. Moreover, serum sCD59 on day 1, 3, and 7 after ROSC could be used for predicting poor 28-day neurological prognosis and all-cause mortality. …”
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    Predictive value of soluble CD59 for poor 28-day neurological prognosis and all-cause mortality in patients after cardiopulmonary resuscitation: a prospective observatory study
  6. 10506
    “…CanICU had 96% sensitivity/73% specificity with the area under the receiver operating characteristic (AUROC) of 0.94 for 28-day, showing better performance than current prognostic models, including the Acute Physiology and Chronic Health Evaluation (APACHE) or Sequential Organ Failure Assessment (SOFA) score. …”
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    Machine Learning-Based Mortality Prediction Model for Critically Ill Cancer Patients Admitted to the Intensive Care Unit (CanICU)
  7. 10507
    “…Age (P <0.001), Sequential Organ Failure Assessment (SOFA) score (P <0.001), Acute Physiology and Chronic Health Evaluation (APACHE) II score (P <0.001), mechanical ventilation time (P <0.001), history of hypertension (P=0.040), heart disease (P=0.040), sedation (P=0.001), and PaO(2)/FiO(2) (P=0.006) were significantly associated with delirium in univariate analysis. …”
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    Relationship between PaO(2)/FiO(2) and delirium in intensive care: A cross-sectional study
  8. 10508
    “…Round-time admissions were more often medical than surgical (12.6% vs. 6.6%; OR 2.06; 95% CI, 1.83-2.31, P < 0.0001), had more comorbid illness (11.9% vs. 10.5%; OR 1.15; 95% CI, 1.04-1.27, P < 0.008) and higher APACHE II score (22.2 vs. 21.3, P < 0.001), and were more likely to have a primary diagnosis of respiratory failure (37.0% vs. 31.3%, P < 0.001) or sepsis (11.1% vs. 9.0%, P = 0.002). …”
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    Impact of intensive care unit admission during morning bedside rounds and mortality: a multi-center retrospective cohort study
  9. 10509
    “…Disease severity, as measured by Sequential Organ Failure Assessment (SOFA) score or Acute Physiology and Chronic Health Evaluation (APACHE) IV score, was not a significant confounding variable. …”
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    A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Cohorts
  10. 10510
    “…To control for comorbidities, the threshold was examined in the low-acuity patients only (APACHE-II score <21, Charlson co-morbidity index <5, or Pitt bacteremia score <4). …”
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    1643. Pharmacodynamics (PD) of Daptomycin (DAP) in Combination Therapy for Enterococcal Bloodstream Infection (BSI)
  11. 10511
    por Raza, Tasleem
    Publicado 2019
    “…The factors associated with mortality include Acute Physiology and Chronic Health Evaluation (APACHE) - II or Sequential Organ Failure Assessment (SOFA) score, vasopressors support, and prolonged hospital stay.(2,3) In most patients with rheumatological disorders, the underlying disease is known at the time of admission. …”
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    Rheumatology in ICU
  12. 10512
    “…Measurements and results (means ± SD): Twenty-four patients aged 49±17 years, admission APACHE II 13±5, were included. Admission PaO(2)/FIO(2), alveolar-arterial oxygen difference (DA-aO(2)) and PaCO(2) were 104±48, 447±120 and 40±10 mmHg, respectively. …”
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    Non-invasive pressure support ventilation in severe community-acquired pneumonia
  13. 10513
    “…RESULTS: Baseline variables that met criteria for significant independent predictors of D28 ACM and CR at EFU in the final selected regression model are in Fig 1 and Fig 2, respectively. As expected, APACHE II score, renal impairment, elderly age, and mechanical ventilation were significant predictors for both outcomes. …”
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    1574. Multivariate Regression Analysis to Determine Independent Predictors of Treatment Outcomes in the RESTORE-IMI 2 Trial
  14. 10514
    “…The CURB-65 (confusion, urea, respiratory, rate, blood pressure plus age ≥65 years), Acute Physiology and Chronic Health Evaluation (APACHE) II and pH value were significantly higher in older patients than in patients who were under 60 years old. …”
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    The effect of age on the clinical and immune characteristics of critically ill patients with COVID-19: A preliminary report
  15. 10515
    “…METHODS: Twenty-five septic ICU patients (19 m, 6f) aged 32–86 years with the mean APACHE II score of 20.2 (range 11–33), suffering mainly from perioperative intra-abdominal or respiratory infections and septic shock (n = 18), were investigated over three days after the start of extended 3-h i.v. infusions of meropenem q8h. …”
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    Impact of cumulative fluid balance on the pharmacokinetics of extended infusion meropenem in critically ill patients with sepsis
  16. 10516
    “…The features age, gender, SaO(2), PaO(2), FIO(2), admission diagnosis, Apache IV, mechanical ventilation (MV), and ICU mortality were extracted. …”
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    Mortality Prediction Using SaO(2)/FiO(2) Ratio Based on eICU Database Analysis
  17. 10517
    “…Furthermore, H3K18la protein expression correlated positively with APACHE II scores, SOFA scores on day 1, ICU stay, mechanical ventilation time and serum lactate (ρ=0.42, 0.63, 0.39, 0.51 and 0.48, respectively, ρ=0.012, 0.000, 0.019, 0.003 and 0.003, respectively). …”
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    Lactylated Histone H3K18 as a Potential Biomarker for the Diagnosis and Predicting the Severity of Septic Shock
  18. 10518
    “…Não houve diferença na proporção de casos positivos para amostras de guano ou swab-orofaríngeo ou entre morcegos machos e fêmeas (valor Z -0,66). CONCLUSÃO: De modo geral os dados indicam para a presença de vírus da família Coronaviridae entre morcegos, nectarívoros abrigam estes vírus em maior proporção e estes animais estão em áreas urbanas indicando a necessidade de realizar o monitoramento dos morcegos e das variantes de Sars-Covs circulantes.…”
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    DESCRIÇÃO DE VÍRUS PERTENCENTES A FAMÍLIA CORONAVIRIDAE EM MORCEGOS NO CERRADO CENTRAL-BRASILEIRO
  19. 10519
    “…High mortality was predicted by baseline severity of illness (median APACHE II score 23, range 21–33.25). Choice of lenient or strict PD targets (ie 100%fT >MIC or 100%fT >4XMIC) had the largest impact on probability of target attainment (PTA), whereas presence or intensity of CKRT had minimal impact on PTA. …”
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    Pharmacokinetics of piperacillin and tazobactam in critically Ill patients treated with continuous kidney replacement therapy: A mini‐review and population pharmacokinetic analysis
  20. 10520
    por Szegedi, Peter
    Publicado 2021
    “…. • Local NVMe SSD: High-speed local flash storage ideal for large databases, high performance computing (HPC), and big data workloads such as Apache Spark and Hadoop. • Block volumes: Standard block storage services offering 60 IOPS per Gb, up to a maximum of 32,000 IOPS per volume, backed by Oracle's highest performance SLA. • Parallel file systems: HPC requires larger data sets and higher performance than standard enterprise file servers can provide. …”
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    Oracle Data Science Cloud
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