“…Results from a recent molecular phylogenetic study of tribe Pisonieae showed that Pisonia is non-monophyletic and comprises three well-supported lineages: one including typical Pisonia and allies (Pisonia s.str.), a clade of species which corresponds to the original description of Ceodes and a third lineage whose single representative was formerly treated under the monotypic genus Rockia. …”
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“…In this paper, we describe two endemic tree species of Pisonia (Caryophyllales: Nyctaginaceae) from Puerto Rico that were erroneously catalogued under the single name Pisonia subcordata var. typica f. gigantophylla, misidentified as P. albida or P. subcordata, and informally named as “P. borinquena” and “P. woodburyana”. …”
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“…This review focuses on the outcomes of four clinical trials of pitolisant to treat narcolepsy. These four trials show that pitolisant is an effective drug to treat EDS and cataplexy in narcolepsy.…”
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“…Twelve new compounds including four isoflavonolignans (1a/1b and 2a/2b), two neolignans (3a/3b), and six isoflavonoids (5–10), together with seven known compounds (4 and 11–16) were isolated from the stems of Pisonia umbellifera. The structures were elucidated on the basis of comprehensive spectroscopic analyses and ECD calculation methods. …”
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“…It is shown that fast pionisation-the process of meson generation, carrying a fixed part of the full velocity-dominates in inclusive spectra of pp collisions. …”
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“…The objective of our study was to evaluate the efficacy of pitolisant, a histamine 3 (H3)-receptor antagonist/inverse agonist, in patients with a high burden of narcolepsy symptoms. …”
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“…The development program of pitolisant was characterized by eight Phase II/III studies. …”
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“…Our research focused on how Pisonia Alba (PA) leaves, which are used to treat wounds, are used to synthesize silver nanoparticles and study their wound healing property. …”
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“…Real-world data collection on pitolisant efficacy and safety is still ongoing. However, pitolisant effectiveness on orgasmolepsy in NT1 has no precedent in the literature. …”
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“…STUDY OBJECTIVES: To asses the long-term safety and efficacy of pitolisant, an histamine H3-receptor antagonist, on narcolepsy. …”
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“…AIM: To assess the non-inferiority of pitolisant, a new compound for the relief of excessive daytime sleepiness (EDS) and cataplexy in narcolepsy, compared with modafinil. …”
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“…It is shown that in the previously suggested rapid pionisation model the height of inclusive spectra and the averaged multiplicity increases as a fourth power and third power, respectively, of the total rapidity (Y=ln( square root s/m/sub p/) in a good agreement with the experimental data, obtained at ISR-CERN. (12 refs).…”
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“…Full-text articles were screened and reviewed to provide an update on pitolisant and other histamine-3 receptor antagonists. …”
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“…This review summarizes the clinical efficacy, safety and tolerability of pitolisant in treating the symptoms of narcolepsy. Randomized and observational studies demonstrate pitolisant to be effective in treating both hypersomnolence and cataplexy while generally being well tolerated at prescribed doses. …”
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“…The pharmacological profile of pitolisant, a histamine H(3) receptor antagonist/inverse agonist, indicates that this compound might reduce body weight and metabolic disturbances. …”
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“…A new species of encyrtid wasp, Ooencyrtus pitosina Polaszek, Noyes & Fusu sp. n., (Hymenoptera: Encyrtidae: Encyrtinae) is described as a gregarious parasitoid in the eggs of the endemic Samoan swallowtail butterfly Papilio godeffroyi (Lepidoptera: Papilionidae) in the Samoan archipelago. …”
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“…The aim of this study was to investigate the influence of pitolisant – H(3) histamine antagonist - on subchronic olanzapine-induced depresion-like symptoms, sedation and hypertriglicerydemia. …”
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