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4“…Three MT isoforms with distinct metal binding preferences are present in the Roman Snail Helix pomatia. Here, we use nuclear magnetic resonance (NMR) to follow the evolution of Cd(2+) and Cu(+) binding from the reconstructed ancestral Stylommatophora MT to the three H. pomatia MT (HpMT) isoforms. …”
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5por Smyrniotopoulos, Vangelis, Rae, Margaret, Soldatou, Sylvia, Ding, Yuanqing, Wolff, Carsten W., McCormack, Grace, Coleman, Christina M., Ferreira, Daneel, Tasdemir, Deniz“…Antifungal bioactivity-guided fractionation of the organic extract of the sponge Polymastia boletiformis, collected from the west coast of Ireland, led to the isolation of two new sulfated steroid-amino acid conjugates (1 and 2). …”
Publicado 2015
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6por Parameswaran, R., Tan, W. B., Nga, M. E., Soon, G. S. T., Ngiam, K. Y., Brooks, S. A., Sadler, G. P., Mihai, R.“…This study aimed to assess alteration in cellular glycosylation, detected by lectin Helix pomatia agglutinin (HPA) binding, in adrenal cancers and to determine whether such altered glycosylation has prognostic significance. …”
Publicado 2018
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9por Duscher, Dominik, Kiesl, David, Aitzetmüller, Matthias, Schmidt, Manfred, Huemer, Georg M.Enlace del recurso
Publicado 2017
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10Publicado 1993“…Six hundred and eighty-four primary breast cancers from the International (Ludwig) Breast Cancer Study Group (IBCSG) were studied for Helix pomatia lectin (HPA) binding. There was a weak correlation between lymph node-positive and HPA positive (P = 0.04). …”
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11por Nasibova, Aygun, Khalilov, Rovshan, Bayramov, Mahammad, Mustafayev, İslam, Eftekhari, Aziz, Abbasov, Mirheydar, Kavetskyy, Taras, Rosić, Gvozden, Selakovic, Dragica“…A study of grape snails (Helix pomatia) using the electron paramagnetic resonance (EPR) spectroscopy method, where shells were exposed to ionizing gamma radiation, indicated that the effect of radiation up to certain doses results in the emergence of magnetic properties in the organism. …”
Publicado 2023
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12“…We investigated the prognostic significance of Helix pomatia lectin (HPA) staining on disease-free and overall survival in 120 primary breast carcinomas. …”
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13“…The extent of lectin binding by three human melanoma (LOX, FEMX-1 and SESX) and two sarcoma lines (MHMX and OHSX) was related to their potential for experimental metastasis formation in athymic nude mice. The Helix pomatia agglutinin (HPA), which recognises the N-acetyl-D-galactosamine ligand, showed differential binding to the cell lines in a manner that correlated with their ability to give lung colonies after i.v. injection in the mice (P < 0.005). …”
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14por Peiris, Diluka, Ossondo, Marlène, Fry, Simon, Loizidou, Marilena, Smith-Ravin, Juliette, Dwek, Miriam V.“…Affinity purification with the carbohydrate binding protein from Helix pomatia agglutinin (HPA) was coupled to 2-dimensional gel electrophoresis with mass spectrometry to enable the identification of low abundance O-linked glycoproteins from human colorectal cancer specimens. …”
Publicado 2015
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15“…It is well known that the Helix pomatia (edible snail) agglutinin (HPA) lectin shows specificity for terminal αGalNAc residues present, among other locations, in the Forssman pentasaccharide (αGalNAc1→3βGalNAc1→3αGal1→4βGal1→4βGlc). …”
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16por Simplicien, Mathias, Barre, Annick, Benkerrou, Yamina, Van Damme, Els J. M., Rougé, Pierre, Benoist, Hervé“…ABSTRACT: Morniga G is a T/Tn-specific lectin, inducing cell death in Tn-positive leukemias but not in healthy lymphocytes. Helix pomatia lectin (HPA) is another T/Tn-specific lectin, currently used as tool for cancer diagnostics. …”
Publicado 2021
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17por Tzertzinis, George, Ganatra, Mehul B., Ruse, Cristian, Taron, Christopher H., Causey, Bryce, Wang, Liang, Schildkraut, Ira“…Uncharacteristically, the H. pomatia AMP deaminase was determined to be dissimilar to the AMP deaminase family by sequence comparison while demonstrating similarity to the ADGFs despite having AMP as its preferred substrate rather than adenosine.…”
Publicado 2023
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18por Gil-Moreno, Selene, Jiménez-Martí, Elena, Palacios, Òscar, Zerbe, Oliver, Dallinger, Reinhard, Capdevila, Mercè, Atrian, Sílvia“…Snail metallothioneins (MTs) constitute an ideal model to study structure/function relationships in these metal-binding polypeptides. Helix pomatia harbours three MT isoforms: the highly specific CdMT and CuMT, and an unspecific Cd/CuMT, which represent paralogous proteins with extremely different metal binding preferences while sharing high sequence similarity. …”
Publicado 2015
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19por Włostowski, Tadeusz, Kozłowski, Paweł, Łaszkiewicz-Tiszczenko, Barbara, Oleńska, Ewa, Aleksandrowicz, Olgierd“…The objectives of this study were (1) to determine cadmium (Cd) accumulation in the midgut gland of a land snail Helix pomatia L. inhabiting residential areas of the 14 largest cities in Poland, and (2) to examine whether the accumulated Cd exerted any toxic effects. …”
Publicado 2014
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