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Mostrando 601 - 620 Resultados de 727 Para Buscar 'rock ácido~', tiempo de consulta: 1.33s Limitar resultados
  1. 601
    “…Here, we identified a highly conserved acidic STD-rich motif of INCENP that is phosphorylated during mitosis in vivo and by Plk1 in vitro and is involved in controlling Aurora B activity. …”
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    Cell cycle-independent furrowing triggered by phosphomimetic mutations of the INCENP STD motif requires Plk1
  2. 602
    “…Our summarized review and analysis show that the pharmacological effects of and mechanisms underlying ginsenoside Rg1 activity against cerebral ischemia and reperfusion injury mainly involve 4 sets of mechanisms: anti-oxidant activity and associated apoptosis via the Akt, Nrf2/HO-1, PPARγ/HO-1, extracellular regulated protein kinases (ERK), p38, and c-Jun N-terminal kinase (JNK) pathways (or mitochondrial apoptosis pathway) and the caspase-3/ROCK1/MLC pathway; anti-inflammatory and immune stimulatory-related activities that involve apoptosis or necrosis via MAPK pathways (the JNK1/2 + ERK1/2 and PPARγ/HO-1 pathways), endoplasmic reticulum stress (ERS), high mobility group protein1 (HMGB1)-induced TLR2/4/9 and receptor for advanced glycation end products (RAGE) pathways, and the activation of NF-κB; neurological cell cycle, proliferation, differentiation, and regeneration via the MAPK pathways (JNK1/2 + ERK1/2, PI3K-Akt/mTOR, PKB/Akt and HIF-1α/VEGF pathways); and energy metabolism and the regulation of cellular ATP levels, the blood-brain barrier and other effects via N-methyl-D-aspartic acid (NMDA) receptors, ERS, and AMP/AMPK-GLUT pathways. …”
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    Protective Effects and Target Network Analysis of Ginsenoside Rg1 in Cerebral Ischemia and Reperfusion Injury: A Comprehensive Overview of Experimental Studies
  3. 603
    por Pang, Yefei, Thomas, Peter
    Publicado 2020
    “…These effects were blocked by cyclopiazonic acid (CPA, a SERCA inhibitor), suggesting that SERCA plays a critical role in P4 induction of VSMC relaxation. …”
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    SUN-559 Involvement of Sarco/Endoplasmic Reticulum Ca- ATPase (SERCA) in Membrane Progesterone Receptor Alpha (PAQR7)-Mediated Progesterone Induction of Vascular Smooth Muscle Relaxation
  4. 604
    “…In addition, we choose a popular seaweed extract—fucoidan was extracted from the same brown algae—Sargassum aquifolium collected from Taiwan-Pingtung-Kenting-Chuanfan Rock. In this research, we used acid hydrolysis to prepared two different molecular weight fucoidan, the small molecular fucoidan (Fus) as drug, and the molecular weight approximately 1 kDa fucoidan (Ful) as the nanoparticle gatekeeper, and as targeting molecule for overexpressed P-selectin on the surface of the metastatic tumors. …”
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    Fucoidan with three functions extracted from Sargassum aquifolium integrated rice-husk synthesis dual-imaging mesoporous silica nanoparticle
  5. 605
    por Bassez, Marie-Paule
    Publicado 2018
    “…It is also shown that the H(2) which is released during hydrolysis/oxidation of fayalite/ferrosilite can lead to components of life, such as macromolecules of amino acids which are synthesized from mixtures of (CO, N(2), H(2)O) in Sabatier-Senderens/Fischer-Tropsch & Haber-Bosch reactions or microwave or gamma-ray excitation reactions. …”
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    Water near its Supercritical Point and at Alkaline pH for the Production of Ferric Oxides and Silicates in Anoxic Conditions. A New Hypothesis for the Synthesis of Minerals Observed in Banded Iron Formations and for the Related Geobiotropic Chemistry inside Fluid Inclusions
  6. 606
    “…AOA and AOB abundances separated according to the geologic age of the parent rock with AOB higher in the more weathered, semi-arid soils of Western Australia. …”
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    Ancient landscapes and the relationship with microbial nitrification
  7. 607
    “…Also, treating the tight carbonate rocks with the optimized chelating agent solutions showed effective wormholes with a minimum acid volume. …”
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    Carbonate Stimulation Using Chelating Agents: Improving the Treatment Performance by Optimizing the Fluid Properties
  8. 608
    “…A bio-organic fertilizer (BoF) was prepared using kitchen waste (79%), chita-dhan (unfilled rice grain) biochar (15%), rock phosphate (5%), and a consortium of 10 PGPB (1%) to supplement 30% nitrogen and to replace triple superphosphate (TSP) fertilizer in rice production with an improvement of soil health. …”
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    Bio-Organic Fertilizer: A Green Technology to Reduce Synthetic N and P Fertilizer for Rice Production
  9. 609
    “…Accordingly, the reaction is more than an order of magnitude faster with 8 methanol molecules per Brønsted acidic site than that with 2 molecules, as evident from the evolution of the methyl rock band of the methoxy species and of water as a function of time. …”
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    Methanol loading dependent methoxylation in zeolite H-ZSM-5
  10. 610
    “…Askival is a light‐toned, coarsely crystalline float rock, which was identified near the base of Vera Rubin Ridge in Gale crater. …”
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    Askival: An altered feldspathic cumulate sample in Gale crater
  11. 611
    “…Tick presence was positively associated with deciduous, dry to mesic forests and alfisol-type soils of sandy or loam-sand textures overlying sedimentary rock. Tick absence was associated with grasslands, conifer forests, wet to wet/mesic forests, acidic soils of low fertility and a clay soil texture, and Precambrian bedrock. …”
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    Predicting the Risk of Lyme Disease: Habitat Suitability for Ixodes scapularis in the North Central United States
  12. 612
    “…This study shows that post-depositional processes in tropical forests result in poor preservation of archaeological materials due to acidic conditions and intensive biological activity within the sediments. …”
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    Site Formation Processes and Hunter-Gatherers Use of Space in a Tropical Environment: A Geo-Ethnoarchaeological Approach from South India
  13. 613
    “…Cyanobacterial symbiosis appears to have enabled lichens to overcome size constraints in oligotrophic environments such as acidic, rain‐washed rock surfaces. In the case of the Placopsis fungal symbiont, this has led to an adaptive radiation of more than 60 recognized species from related crustose members of the genus Trapelia. …”
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    Escape from the cryptic species trap: lichen evolution on both sides of a cyanobacterial acquisition event
  14. 614
    por Tan, Jonathan, Sephton, Mark A.
    Publicado 2020
    “…Mars analog sites provide the opportunity to study how life could have exploited such habitable conditions. Acidic iron- and sulfur-rich streams are good geochemical analogues for the late Noachian and early Hesperian, periods of martian history where habitable conditions were widespread. …”
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    Organic Records of Early Life on Mars: The Role of Iron, Burial, and Kinetics on Preservation
  15. 615
    “…Pharmacological inhibition of the GTPase-dynamin and the fatty acid transporter-2 reduced lipid uptake by 28.5 and 35%, respectively. …”
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    Genomics of lipid-laden human hepatocyte cultures enables drug target screening for the treatment of non-alcoholic fatty liver disease
  16. 616
    “…Bacterial lipids are well-preserved in ancient rocks and certain ones have been used as indicators of specific bacterial metabolisms or environmental conditions existing at the time of rock deposition. …”
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    Anaerobic 3-methylhopanoid production by an acidophilic photosynthetic purple bacterium
  17. 617
    “…BACKGROUND: Cyanidiales are unicellular extremophilic red algae that inhabit acidic and high temperature sites around hot springs and have also adapted to life in endolithic and interlithic habitats. …”
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    Establishment of endolithic populations of extremophilic Cyanidiales (Rhodophyta)
  18. 618
    “…IMPORTANCE Pseudomonas aeruginosa is an opportunistic pathogen whose multidrug resistance demands new drug development. Fatty acids are essential for viability, and essential genes are ideal drug targets. …”
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    Analysis of the Plasmid-Based ts-Mutant ΔfabA/pTS-fabA Reveals Its Lethality under Aerobic Growth Conditions That Is Suppressed by Mild Overexpression of desA at a Restrictive Temperature in Pseudomonas aeruginosa
  19. 619
    por King, Ashley J., Daly, Luke, Rowe, James, Joy, Katherine H., Greenwood, Richard C., Devillepoix, Hadrien A. R., Suttle, Martin D., Chan, Queenie H. S., Russell, Sara S., Bates, Helena C., Bryson, James F. J., Clay, Patricia L., Vida, Denis, Lee, Martin R., O’Brien, Áine, Hallis, Lydia J., Stephen, Natasha R., Tartèse, Romain, Sansom, Eleanor K., Towner, Martin C., Cupak, Martin, Shober, Patrick M., Bland, Phil A., Findlay, Ross, Franchi, Ian A., Verchovsky, Alexander B., Abernethy, Feargus A. J., Grady, Monica M., Floyd, Cameron J., Van Ginneken, Matthias, Bridges, John, Hicks, Leon J., Jones, Rhian H., Mitchell, Jennifer T., Genge, Matthew J., Jenkins, Laura, Martin, Pierre-Etienne, Sephton, Mark A., Watson, Jonathan S., Salge, Tobias, Shirley, Katherine A., Curtis, Rowan J., Warren, Tristram J., Bowles, Neil E., Stuart, Finlay M., Di Nicola, Luigia, Györe, Domokos, Boyce, Adrian J., Shaw, Kathryn M. M., Elliott, Tim, Steele, Robert C. J., Povinec, Pavel, Laubenstein, Matthias, Sanderson, David, Cresswell, Alan, Jull, Anthony J. T., Sýkora, Ivan, Sridhar, Sanjana, Harrison, Richard J., Willcocks, Francesca M., Harrison, Catherine S., Hallatt, Daniel, Wozniakiewicz, Penny J., Burchell, Mark J., Alesbrook, Luke S., Dignam, Aishling, Almeida, Natasha V., Smith, Caroline L., Clark, Brett, Humphreys-Williams, Emma R., Schofield, Paul F., Cornwell, Luke T., Spathis, Vassilia, Morgan, Geraint H., Perkins, Mark J., Kacerek, Richard, Campbell-Burns, Peter, Colas, Francois, Zanda, Brigitte, Vernazza, Pierre, Bouley, Sylvain, Jeanne, Simon, Hankey, Mike, Collins, Gareth S., Young, John S., Shaw, Clive, Horak, Jana, Jones, Dave, James, Nick, Bosley, Steve, Shuttleworth, Alan, Dickinson, Paul, McMullan, Ian, Robson, Derek, Smedley, Andrew R. D., Stanley, Ben, Bassom, Richard, McIntyre, Mark, Suttle, Adam A., Fleet, Richard, Bastiaens, Luc, Ihász, Míra B., McMullan, Sarah, Boazman, Sarah J., Dickeson, Zach I., Grindrod, Peter M., Pickersgill, Annemarie E., Weir, Colin J., Suttle, Fiona M., Farrelly, Sarah, Spencer, Ieun, Naqvi, Sheeraz, Mayne, Ben, Skilton, Dan, Kirk, Dan, Mounsey, Ann, Mounsey, Sally E., Mounsey, Sarah, Godfrey, Pamela, Bond, Lachlan, Bond, Victoria, Wilcock, Cathryn, Wilcock, Hannah, Wilcock, Rob
    Publicado 2022
    “…It contains abundant hydrated silicates formed during fluid-rock reactions, and carbon- and nitrogen-bearing organic matter including soluble protein amino acids. …”
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    The Winchcombe meteorite, a unique and pristine witness from the outer solar system
  20. 620
    “…Aluminium (Al)-rich palaeosols—i.e., palaeobauxite deposits—should have formed in karst depressions in carbonate sequences as a result of acidic solutions from oxidative weathering of sulfide minerals during the Great Oxidation Event (GOE), but no GOE-related karst-palaeobauxite deposits have so far been recorded. …”
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    Karst-bauxite formation during the Great Oxidation Event indicated by dating of authigenic rutile and its thorium content
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