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82“…Effective treatments for improving prognosis of myocardial fibrosis are needed to be further developed. Methyl ferulic acid (MFA), a biologically active monomer extracted and purified from the Chinese herbal medicine, is reported as an attenuator in many diseases. …”
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84“…LPH produced by the chemical process possess 30.3% essential amino acids. This content is comparable with the essential amino acid content of fish protein, a commonly recognized food resource for essential amino acid supplement for human. …”
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85por Watanabe, Noriaki, Takahashi, Kaori, Takahashi, Ryota, Nakamura, Kengo, Kumano, Yusuke, Akaku, Kohei, Tamagawa, Tetsuya, Komai, Takeshi“…Improving geothermal systems through hydraulic stimulation to create highly permeable fractured rocks can induce seismicity. Therefore, the technique must be applied at a moderate intensity; this has led to concerns of insufficient permeability enhancement. …”
Publicado 2021
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86“…The proposed sample preparation procedure avoids the use of perchloric acid and provided accurate results even for silicon determination using an acid digestion with hydrofluoric acid. …”
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87por Wang, Jichao, Sui, Xinyue, Ding, Yamei, Fu, Yingxin, Feng, Xinjun, Liu, Min, Zhang, Youming, Xian, Mo, Zhao, GuangEnlace del recurso
Publicado 2020
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88por De la Rosa, José Maria, Martin-Sanchez, Pedro M., Sanchez-Cortes, Santiago, Hermosin, Bernardo, Knicker, Heike, Saiz-Jimenez, Cesareo“…Their chemical structures as suggested by the data are not related to 3,4-dihydroxyphenylalanine, 5,6-dihydroxyindole or 1,8-dihydroxynaphthalene precursors and likely the building blocks from the melanins have to be based on other phenols that react with the N-terminal amino acid of proteins. The analytical pyrolysis of the acid hydrolysed melanin from O. lascauxensis supports this assumption.…”
Publicado 2017
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89“…In this study, the Dukpyung and the Chubu areas were selected to investigate the migration and enrichment of As and other toxic elements in soils and crop plants in areas covered with black shale. Rock and soil samples digested in 4-acid solution (HCl+HNO(3)+HF+HClO(4)) were analyzed for As and other heavy metals by ICP-AES and ICP-MS, and plant samples by INAA. …”
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90por Ida, Yosuke, Sato, Tatsuya, Umetsu, Araya, Watanabe, Megumi, Furuhashi, Masato, Hikage, Fumihito, Ohguro, Hiroshi“…To elucidate the additive effects of the ROCK inhibitors (ROCK-i), ripasudil (Rip) and Y27632 on bimatoprost acid (BIM-A), a prostaglandin analog (PG), on adipose tissue, two- and three-dimensional (2D or 3D) cultures of 3T3-L1 cells, the most well characterized cells in the field of lipid research, were used. …”
Publicado 2022
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91“…When the sparingly soluble igneous phosphate rock (PR) from Quebec, or when the chemical hydroxyapatite were used as sole phosphorus (P) source, hyphobacteria Rhizobium miluonense Rm3 and Burkholderia anthina Ba8 produced significantly more biofilms than mycorrhizobacteria Rahnella sp. …”
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92por Hori, Akiko, Nishide, Kenji, Yasukuni, Yuki, Haga, Kei, Kakuta, Wataru, Ishikawa, Yasuyuki, Hayes, Matthew J., Ohnuma, Shin-ichi, Kiyonari, Hiroshi, Kimura, Kazuhiro, Kondo, Toru, Sasai, Noriaki“…Overexpression of Prom1 in RPE-1 cells triggers multiple, long, cholesterol-enriched fibres, independently of actin and microtubule polymerisation. A five amino acid stretch located at the carboxyl cytosolic region is essential for fibre formation. …”
Publicado 2019
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93“…Under the action of aqueous acid, the primary phosphate minerals (collophosphate and apatite) and Al-bearing rocks transformed into a typical weathered mineral, sasaite. …”
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94por Nalkurthi, Christina, Schroder, Wayne A., Melino, Michelle, Irvine, Katharine M., Nyuydzefe, Melanie, Chen, Wei, Liu, Jing, Teng, Michele W.L., Hill, Geoffrey R., Bertolino, Patrick, Blazar, Bruce R., Miller, Gregory C., Clouston, Andrew D., Zanin-Zhorov, Alexandra, MacDonald, Kelli P.A.“…CONCLUSIONS: As IL-17 and IgG–Fc binding promote pathogenic macrophage differentiation, together our data demonstrate that ROCK2 inhibition prevents and reverses liver fibrosis through direct and indirect effects on macrophage function and highlight the therapeutic potential of ROCK2 inhibition in liver fibrosis. …”
Publicado 2021
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95“…Under acidic conditions near the surface, carbonate rock microstructure changes can directly reflect structural failure characteristics. …”
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98por Yousif, Mariam H. M., Makki, Batoul, El-Hashim, Ahmed Z., Akhtar, Saghir, Benter, Ibrahim F.“…We characterized the effects of diabetes and/or chronic in vivo administration of Ang-(1-7) on vascular reactivity in the rat corpus cavernosum (CC) and on protein expression levels of potential downstream effectors of the renin-angiotensin-aldosterone system (RAAS) such as angiotensin-converting enzyme (ACE), ACE2, Rho kinases 1 and 2 (ROCK1 and ROCK2), and omega-hydroxylase, the cytochrome-P450 enzyme that metabolizes arachidonic acid to form the vasoconstrictor, 20-hydroxyeicosatetraenoic acid. …”
Publicado 2014
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99por Vernardis, Spyros I., Terzoudis, Konstantinos, Panoskaltsis, Nicki, Mantalaris, Athanasios“…Exposure for 48 hours resulted in reduction in glycolysis, glutaminolysis, the citric acid (TCA) cycle as well as the amino acids pools, suggesting the adaptation of the cells to the new culture conditions, which was also reflected by the expression of the metabolic regulators, mTORC1 and tp53 and correlated with cellular proliferation status. …”
Publicado 2017
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100por Sharif, Muhammad, Baek, Yeong-Bin, Naveed, Ahsan, Stalin, Nattan, Kang, Mun-Il, Park, Sang-Ik, Soliman, Mahmoud, Cho, Kyoung-Oh“…Here, we found that the RhoA/Rho-associated protein kinase (ROCK)/myosin light chain (MLC) signaling pathway was activated in polarized LLC-PK cells during the early infection of PSaV Cowden strain in the presence of bile acid. …”
Publicado 2021
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