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50por Kinsella, Paul M., Karapanagiotidis, Theo, Nicholson, Suellen, Williamson, Deborah A.Enlace del recurso
Publicado 2022
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51por Bolton, Jessica, Chaudhury, Sidhartha, MacGill, Randall S., Early, Angela M., King, C. Richter, Locke, Emily, Neafsey, Daniel E., Bergmann-Leitner, Elke S.“…Profiling of serological responses to establish the landscape of antibody specificities in individuals exposed to pathogens or vaccines is crucial for (a) revealing humoral immune correlates of protection; (b) uncovering markers of pathogen exposure; and (c) identifying antigens and epitopes associated with disease vs. • The newly developed protocol outlines high-throughput profiling of serological responses using a multiplex testing platform with subsequent computational analysis. • The protocol is a modification of the basic assay development manual from the manufacturer of the MESO QuickPlex SQ 120 instrument (MSD, Gaithersburg, MD) and can be used for synthetic peptides as well as full length proteins. • The protocol can be applied to map serological responses to pathogens or pathogen-derived antigens to establish serological profiles in search for biomarkers or immune correlates.…”
Publicado 2021
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53“…The fact that steric isomers are acted upon selectively by immune sera may be supposed to play a significant part in the serological specificity of carbohydrates such as those discovered in bacterial antigens.…”
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55“…Marked disparity was found between the reactions of peptides and corresponding amides indicating differences between acid and other polar groups in their influence on serological specificity.…”
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56por Stein, George J.“…The results indicate that treatment of the spirochetes of relapsing fever with saponin yields a relatively stable antigenic preparation which may prove useful in the serological diagnosis of this disease.…”
Publicado 1944
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58por Davison, Peter F., Levine, Lawrence, Drake, Maurice P., Rubin, Albert, Bump, Susan“…Tropocollagen preparations from carp, buffalo fish, rats, calves, sheep, and humans have been studied by electron microscopy and serologic methods. Tropocollagens from each species appeared identical by electron microscopy but they were readily distinguished (except between sheep and calves) by C'-fixation tests with rabbit antisera against the various tropocollagens. …”
Publicado 1967
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