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1por Ponomarenko, Mikhail, Rasskazov, Dmitry, Arkova, Olga, Ponomarenko, Petr, Suslov, Valentin, Savinkova, Ludmila, Kolchanov, Nikolay“…We used our Web service involving Fisher's Z-score for candidate SNP markers to find a significant change in a gene's expression. Here we analyzed the change caused by SNPs in the gene's promoter via a change in affinity of the TATA-binding protein for this promoter. …”
Publicado 2015
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3por Smith, Sarah M., Yarwood, Andrew, Fleck, Roland A., Robinson, Colin, Smith, Corinne J.“…This is the first indication that TatA organisation in the inner membrane alters in response to changes in Tat subunit stoichiometry.…”
Publicado 2017
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5por Zhang, Yijun, Fan, Miaomiao, Zhang, Xue, Huang, Feng, Wu, Kang, Zhang, Junsong, Liu, Jun, Huang, Zhuoqiong, Luo, Haihua, Tao, Liang, Zhang, HuiEnlace del recurso
Publicado 2014
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6por Ponomarenko, Petr, Rasskazov, Dmitry, Suslov, Valentin, Sharypova, Ekaterina, Savinkova, Ludmila, Podkolodnaya, Olga, Podkolodny, Nikolay L., Tverdokhleb, Natalya N., Chadaeva, Irina, Ponomarenko, Mikhail, Kolchanov, Nikolay“…Using Web service SNP_TATA_Comparator presented in our previous paper, here we analyzed immediate surroundings of known SNP markers of diseases and identified several candidate SNP markers that can significantly change the affinity of TATA-binding protein for human gene promoters, with circadian consequences. …”
Publicado 2016
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8por Arkova, Olga V, Ponomarenko, Mikhail P, Rasskazov, Dmitry A, Drachkova, Irina A, Arshinova, Tatjana V, Ponomarenko, Petr M, Savinkova, Ludmila K, Kolchanov, Nikolay A“…We also measured half-life (t(1/2)), Gibbs free energy change (ΔG), and the association and dissociation rate constants, k(a )and k(d), of the TBP-DNA complex for these SNPs. …”
Publicado 2015
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9por Chadaeva, Irina V., Ponomarenko, Petr M., Rasskazov, Dmitry A., Sharypova, Ekaterina B., Kashina, Elena V., Zhechev, Dmitry A., Drachkova, Irina A., Arkova, Olga V., Savinkova, Ludmila K., Ponomarenko, Mikhail P., Kolchanov, Nikolay A., Osadchuk, Ludmila V., Osadchuk, Alexandr V.“…With this in mind, one of genome-based developments at the junction of personalized medicine and bioinformatics will be considered in this work, where we used two Web services: (i) SNP_TATA_Comparator to search for alleles with a single nucleotide polymorphism (SNP) that alters the affinity of TATA-binding protein (TBP) for the TATA boxes of human gene promoters and (ii) PubMed to look for retrospective clinical reviews on changes in physiological indicators of reproductive potential in carriers of these alleles. …”
Publicado 2018
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10“…Depolarization and cAMP signals induce preferential transcription of activity-dependent genes containing promoters with proximal CRE/TATA sequences, such as c-fos, Dusp1, Nr4a1, Nr4a2 and Ptgs2, but not genes with proximal CRE/TATA-less promoters (e.g. …”
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11por Bondili, Suresh Kumar, Nandhana, Ravindra, Dhanawat, Aditya, Noronha, Vanita, Joshi, Amit, Patil, Vijay Maruti, Menon, Nandini, Kaushal, Rajiv Kumar, Choughule, Anuradha, Jiwnani, Sabita S, Janu, Amit, Prabhash, Kumar“…BACKGROUND: Pulmonary sarcomatoid carcinoma (PSC) constitutes a heterogeneous group of poorly differentiated non-small cell lung cancers. Since these are rare tumours, we sought to determine the characteristics and clinical outcomes of these patients treated at our centre. …”
Publicado 2022
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12por Ponomarenko, Petr, Chadaeva, Irina, Rasskazov, Dmitry A., Sharypova, Ekaterina, Kashina, Elena V., Drachkova, Irina, Zhechev, Dmitry, Ponomarenko, Mikhail P., Savinkova, Ludmila K., Kolchanov, NikolayEnlace del recurso
Publicado 2017
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13por Tjitro, Ryan, Campbell, Lee A., Basova, Liana, Johnson, Jessica, Najera, Julia A., Lindsey, Alexander, Marcondes, Maria Cecilia GaribaldiEnlace del recurso
Publicado 2019
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14por Zhang, Yijun, Fan, Miaomiao, Geng, Guannan, Liu, Bingfeng, Huang, Zhuoqiong, Luo, Haihua, Zhou, Jie, Guo, Xuemin, Cai, Weiping, Zhang, HuiEnlace del recurso
Publicado 2014
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15“…There is an unmet need to find new molecular therapeutic targets for GIST. TATA-box-binding protein-associated factor 15 (TAF15) contributes to the progress of various tumors, while the role and molecular mechanism of TAF15 in GIST progression are still unknown. …”
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16por Ponomarenko, Mikhail P., Arkova, Olga, Rasskazov, Dmitry, Ponomarenko, Petr, Savinkova, Ludmila, Kolchanov, NikolayEnlace del recurso
Publicado 2016
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17por Chadaeva, Irina V., Ponomarenko, Mikhail P., Rasskazov, Dmitry A., Sharypova, Ekaterina B., Kashina, Elena V., Matveeva, Marina Yu, Arshinova, Tatjana V., Ponomarenko, Petr M., Arkova, Olga V., Bondar, Natalia P., Savinkova, Ludmila K., Kolchanov, Nikolay A.Enlace del recurso
Publicado 2016
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18“…Here we use such a genome-wide annotation for comprehensively studying promoter architecture in yeast, focusing on the distribution of transcription factor binding sites relative to transcription start sites, and the architecture of TATA and TATA-less promoters. For most transcription factors, binding sites are positioned further upstream and vary over a wider range in TATA promoters than in TATA-less promoters. …”
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19por White, Gaye F., Schermann, Sonya M., Bradley, Justin, Roberts, Andrew, Greene, Nicholas P., Berks, Ben C., Thomson, Andrew J.“…Analysis of inter-spin distances suggested that the transmembrane helices of TatA subunits are arranged as a single-walled ring containing a contact interface between Ile(12) on one subunit and Val(14) on an adjacent subunit. …”
Publicado 2010
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20por Tibdewal, Anil, Pathak, Rima, Kumar, Anuj, Anand, Sachith, Ghosh Laskar, Sarbani, Sarin, Rajiv, Chopra, Supriya, Engineer, Reena, Laskar, Siddharth, Murthy, Vedang, Gupta, Tejpal, Agarwal, Jai Prakash“…PURPOSE: Delivery of cancer care during the pandemic required adopting various changes in the standard management. We analyzed the impact of the first wave of the COVID-19 pandemic on radiation oncology treatment practices at Tata Memorial Hospital in India. …”
Publicado 2022
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