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2101por Eudailey, Joshua A., Dennis, Maria L., Parker, Morgan E., Phillips, Bonnie L., Huffman, Tori N., Bay, Camden P., Hudgens, Michael G., Wiseman, Roger W., Pollara, Justin J., Fouda, Genevieve G., Ferrari, Guido, Pickup, David J., Kozlowski, Pamela A., Van Rompay, Koen K. A., De Paris, Kristina, Permar, Sallie R.“…In the present study, we tested the efficacy of a maternal vaccine regimen consisting of a modified vaccinia virus Ankara (MVA) 1086.C gp120 prime-combined intramuscular-intranasal gp120 boost administered during pregnancy and postpartum to confer passive protection on infant rhesus macaques against weekly oral exposure to subtype C simian-human immunodeficiency virus 1157ipd3N4 (SHIV1157ipd3N4) starting 6 weeks after birth. …”
Publicado 2018
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2102por Nadai, Yuka, Held, Kathrin, Joseph, Sarah, Ahmed, Mohamed I. M., Hoffmann, Verena S., Peterhoff, David, Missanga, Marco, Bauer, Asli, Joachim, Agricola, Reimer, Ulf, Zerweck, Johannes, McCormack, Sheena, Cope, Alethea V., Tatoud, Roger, Shattock, Robin J., Robb, Merlin Lee, Sandstroem, Eric G., Hoelscher, Michael, Maboko, Leonard, Bakari, Muhammad, Kroidl, Arne, Wagner, Ralf, Weber, Jonathan, Pollakis, Georgios, Geldmacher, Christof“…Both trials consisted of three immunizations with DNA, followed by two boosts with recombinant Modified Vaccinia Virus Ankara (MVA), either mediating secretion of gp120 (UK003SG) or the presentation of cell membrane bound gp150 envelopes (TMV01) from infected cells, and an additional two boosts with 5 μg of CN54gp140 protein adjuvanted with glucopyranosyl lipid adjuvant (GLA). …”
Publicado 2019
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2103por Pollara, Justin, Jones, Dorothy I., Huffman, Tori, Edwards, R. Whitney, Dennis, Maria, Li, Shuk Hang, Jha, Shalini, Goodman, Derrick, Kumar, Amit, LaBranche, Celia C., Montefiori, David C., Fouda, Genevieve G., Hope, Thomas J., Tomaras, Georgia D., Staats, Herman F., Ferrari, Guido, Permar, Sallie R.“…Detailed comparisons of the HIV-1-specific IgG response were performed on serum from rabbits and RM given identical modified vaccinia virus Ankara-prime/gp120-boost immunization regimens. We found that vaccine-induced neutralizing antibody, gp120-binding antibody levels and immunodominant specificities, antibody-dependent cellular phagocytosis of HIV-1 virions, and antibody-dependent cellular cytotoxicity (ADCC) responses against gp120-coated target cells were similar in rabbits and RM. …”
Publicado 2019
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2104por Vázquez-Ramírez, Daniel, Genzel, Yvonne, Jordan, Ingo, Sandig, Volker, Reichl, Udo“…We here illustrate our strategy for production of the modified vaccinia Ankara (MVA) virus isolate MVA-CR19 in the avian suspension cell line AGE1.CR.pIX at HCD. …”
Publicado 2018
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2105por Green, Christopher A., Sande, Charles J., Scarselli, Elisa, Capone, Stefania, Vitelli, Alessandra, Nicosia, Alfredo, Silva-Reyes, Laura, Thompson, Amber J., de Lara, Catherine M., Taylor, Kathryn S., Haworth, Kathryn, Hutchings, Claire L., Cargill, Tamsin, Angus, Brian, Klenerman, Paul, Pollard, Andrew J.“…The replication-defective chimpanzee adenovirus (PanAd3-RSV) and modified vaccinia virus Ankara (MVA-RSV) vaccines were shown to be safe and immunogenic in young healthy adults. …”
Publicado 2019
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2106“…MATERIAL AND METHODS: This prospective, open-label clinical phase-3 study was conducted at Ankara University Faculty of Medicine, Department of Ophthalmology between April 2019 and April 2021. …”
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2107por Styles, Tiffany M., Gangadhara, Sailaja, Reddy, Pradeep B. J., Sahoo, Anusmita, Shiferaw, Ayalensh, Welbourn, Sarah, Kozlowski, Pamela A., Derdeyn, Cynthia A., Velu, Vijayakumar, Amara, Rama Rao“…Here, we compared the immunogenicity and efficacy of two modified vaccinia Ankara (MVA) vaccines based on variable loop 2 hotspot (V2 HS) optimized C.1086 envelope (Env) sequences, one expressing the membrane anchored gp150 (MVA-150) and the other expressing soluble uncleaved pre-fusion optimized (UFO) gp140 trimer (MVA-UFO) in a DNA prime/MVA boost approach against heterologous tier 2 SHIV1157ipd3N4 intrarectal challenges in rhesus macaques (RMs). …”
Publicado 2022
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2108“…METHODS: A cross-sectional study was performed among health professionals working at a tertiary hospital in Turkey’s capital Ankara. An occupation based stratified sampling was done with taking alpha 0.05 and 1-beta 0.80. …”
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2109por Sacherl, Julia, Kosinska, Anna D., Kemter, Kristina, Kächele, Martin, Laumen, Sabine C., Kerth, Hélène A., Öz, Edanur Ates, Wolff, Lisa S., Su, Jinpeng, Essbauer, Sandra, Sutter, Gerd, Scholz, Martin, Singethan, Katrin, Altrichter, Jens, Protzer, Ulrike“…The therapeutic hepatitis B vaccine TherVacB combines protein priming with a Modified Vaccinia virus Ankara (MVA)-vector boost to break immune tolerance in chronic HBV infection. …”
Publicado 2022
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2110Publicado 2022“…The topics under this symposium and speakers are listed as below: Topic 1: Climate Change: Disaster in the pipeline Dr Dinakaran D, MD, PDF, Assistant professor, Centre for Psychosocial Support in Disaster Management, NIMHANS, Bangalore Topic 2: Climate and its Bearing on Mental Health Dr Ravi kumar N, MD, (Ex-NIMHANS) Consultant Psychiatrist, VARMA Super-speciality Hospital, West Godavari (dt), A.P Topic 3: Does Climate Change increase the prevalence of Mental illness Dr Venkata Lakshmi Narasimha, MD, DM (Ex-NIMHANS) Assistant Professor, Department of Psychiatry, AIIMS, Deoghar, Jharkhand. …”
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2111por Luque Raigón, José Miguel“…En él se generarán colisiones protón-protón en las que se alcanzará una energía centro de masas de 14 TeV y tendrá capacidad de operar a una luminosidad nominal de hasta 1034cm 2s-1. …”
Publicado 2017
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2112por Zhang, Shuyan, Zhang, Weisheng, Martin, Jerome Jeyakumar John, Qadri, Rashad, Fu, Xiaopeng, Feng, Meili, Wei, Lu, Zhang, Anni, Yang, Cheng, Cao, Hongxing“…METHODS: The fruit of two shell types of oil palm, Pisifera (MP) and Tenera (MT), were used to study the changes of fruit souring at different times points of postharvesting, combined with LC-MS/MS metabolomics and RNA-seq transcriptomics techniques to analyze the dynamic changes of free fatty acids during fruit rancidity, and to find out the key enzyme genes and proteins in the process of free fatty acid synthesis and degradation according to metabolic pathways. …”
Publicado 2023
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2113por Fathi, Anahita, Dahlke, Christine, Hardtke, Svenja, Mellinghoff, Sibylle C, Mayer, Leonie, Weskamm, Leonie M, Krähling, Verena, Müller-Kräuter, Helena, Ly, My L, Friedrich, Monika, Hesterkamp, Thomas J, Volz, Asisa, Sutter, Gerd, Becker, Stephan, Addo, Marylyn“…BACKGROUND: Recombinant Modified Vaccinia virus Ankara (MVA) is a replication-deficient viral vector platform with a favorable safety profile that is currently developed for multiple indications, including vaccines against emerging infections. …”
Publicado 2023
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2114por Swadling, Leo, Halliday, John, Kelly, Christabel, Brown, Anthony, Capone, Stefania, Ansari, M. Azim, Bonsall, David, Richardson, Rachel, Hartnell, Felicity, Collier, Jane, Ammendola, Virginia, Del Sorbo, Mariarosaria, Von Delft, Annette, Traboni, Cinzia, Hill, Adrian V. S., Colloca, Stefano, Nicosia, Alfredo, Cortese, Riccardo, Klenerman, Paul, Folgori, Antonella, Barnes, Eleanor“…A recombinant chimpanzee adenoviral (ChAd3) vector and a modified vaccinia Ankara (MVA), encoding the non-structural proteins of HCV (NSmut), used in a heterologous prime/boost regimen induced multi-specific, high-magnitude, durable HCV-specific CD4+ and CD8+ T-cell responses in healthy volunteers, and was more immunogenic than a heterologous Ad regimen. …”
Publicado 2016
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2115por Kahyaoglu, Serkan, Yumuşak, Omer Hamid, Ozyer, Sebnem, Pekcan, Meryem Kuru, Erel, Merve, Cicek, Mahmut Nedim, Erkaya, Salim, Tasci, Yasemin“…MATERIALS AND METHODS: This cross-sectional study was conducted among 84 infertile women with PCOS who were treated with CC at Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara, Turkey, between January 2014 and January 2015. …”
Publicado 2017
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2116por Hartnell, Felicity, Brown, Anthony, Capone, Stefania, Kopycinski, Jakub, Bliss, Carly, Makvandi-Nejad, Shokouh, Swadling, Leo, Ghaffari, Emma, Cicconi, Paola, Del Sorbo, Mariarosaria, Sbrocchi, Roberta, Esposito, Ilaria, Vassilev, Ventzislav, Marriott, Paula, Gardiner, Clair M., Bannan, Ciaran, Bergin, Colm, Hoffmann, Matthias, Turner, Bethany, Nicosia, Alfredo, Folgori, Antonella, Hanke, Tomáš, Barnes, Eleanor, Dorrell, Lucy“…We developed a novel vaccination regimen involving replication-defective and serologically distinct chimpanzee adenovirus (ChAd3, ChAd63) vector priming followed by modified vaccinia Ankara (MVA) boosts, for simultaneous delivery of HCV non-structural (NSmut) and HIV-1 conserved (HIVconsv) region immunogens. …”
Publicado 2019
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2117por Wang, Xiuli, Urak, Ryan, Walter, Miriam, Guan, Min, Han, Tianxu, Vyas, Vibhuti, Chien, Sheng-Hsuan, Gittins, Brenna, Clark, Mary C, Mokhtari, Sally, Cardoso, Angelo, Diamond, Don J, Zaia, John, Forman, Stephen J, Nakamura, Ryotaro“…We plan to initiate a clinical trial at City of Hope using CMV-CD19CAR T cells for patients with intermediate/high-grade B cell non-Hodgkin’s lymphoma immediately after autologous hematopoietic cell transplantation followed by vaccination with a novel CMV vaccine based on Modified Vaccinia Ankara (Triplex) 28 days and 56 days post-T cell infusion.…”
Publicado 2022
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2118por Tekiner, Selda Ayşe, Çullas Ilarslan, Nisa Eda, Günay, Fatih, Ceyhun Peker, Gülsen Ayşe“…MATERIALS AND METHODS: This is a cross-sectional study and we aimed to reach all mothers with babies between 0 and 24 months of age who applied to the Healthy Child Care Policlinic of Ankara University Faculty of Medicine Hospital between July 1 and August 31, 2020 Questionnaires measuring the level of knowledge about COVID-19 disease and breast milk and questionnaires measuring anxiety levels were administered to mothers. …”
Publicado 2022
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2119por Keskin, Müge, Polat, Sefika Burcak, Ates, İhsan, İzdes, Seval, Güner, Hatice Rahmet, Topaloglu, Oya, Ersoy, Reyhan, Cakır, Bekir“…Methods: Our retrospective study included 311 PCR-positive COVID-19 patients over the age of 18 who were hospitalized in Ankara City Hospital Infectious Diseases Department or Intensive Care Unit (ICU) between 15 March 2020 and 15 May 2020. …”
Publicado 2022
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2120por Thogata, Harshitha, Garikipati, Sushmitha, Reddy S, Shanthi, Abhinav Reddy, Pathe, Kumar Jella, Harish“…Methods: This retrospective analysis included individuals who received transcatheter aortic valve replacement (TAVR) at Sri Venkata Sai (SVS) Medical College, Mahabubnagar, Telangana, India, between January 2020 and July 2023. …”
Publicado 2023
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