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281“…BACKGROUND: Modified Vaccinia Ankara (MVA) is a highly attenuated strain of vaccinia virus (VV) that has lost approximately 15% of the VV genome, along with the ability to replicate in most mammalian cells. …”
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283por Hessel, Annett, Schwendinger, Michael, Fritz, Daniela, Coulibaly, Sogue, Holzer, Georg W., Sabarth, Nicolas, Kistner, Otfried, Wodal, Walter, Kerschbaum, Astrid, Savidis-Dacho, Helga, Crowe, Brian A., Kreil, Thomas R., Barrett, P. Noel, Falkner, Falko G.“…METHODOLOGY/PRINCIPAL FINDINGS: For this purpose, the hemagglutinin (HA) and neuraminidase (NA) genes of the influenza A/California/07/2009 (H1N1) strain (CA/07) were inserted into the replication-deficient modified vaccinia Ankara (MVA) virus - a safe poxviral live vector – resulting in MVA-H1-Ca and MVA-N1-Ca vectors. …”
Publicado 2010
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284por Bull, Tim J, Vrettou, Christina, Linedale, Richard, McGuinnes, Catherine, Strain, Sam, McNair, Jim, Gilbert, Sarah C, Hope, Jayne C“…We have evaluated the utility of a viral delivery regimen of non-replicative human Adenovirus 5 and Modified Vaccinia virus Ankara recombinant for early entry MAP specific antigens (HAV) to show protection against challenge in a calf model and extensively screened for differential immunological markers associated with protection. …”
Publicado 2014
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285por Dowall, Stuart D., Graham, Victoria A., Rayner, Emma, Hunter, Laura, Watson, Robert, Taylor, Irene, Rule, Antony, Carroll, Miles W., Hewson, Roger“…The most promising candidate, which has previously been shown to confer protection in the small animal model, is a modified Vaccinia Ankara virus vector expressing the CCHF viral glycoprotein (MVA-GP). …”
Publicado 2016
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286por Volz, Asisa, Jany, Sylvia, Freudenstein, Astrid, Lantermann, Markus, Ludwig, Holger, Sutter, Gerd“…The highly attenuated Modified Vaccinia virus Ankara (MVA) lacks most of the known vaccinia virus (VACV) virulence and immune evasion genes. …”
Publicado 2018
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287por Merad, Yanis, Gaymard, Alexandre, Cotte, Laurent, Perpoint, Thomas, Alfaiate, Dulce, Godinot, Matthieu, Becker, Agathe, Cannesson, Olivier, Batalla, Anne-Sophie, Oria-Yassir, Fatima, Landré, Sophie, Morfin, Florence, Bouscambert, Maude, Valour, Florent, Ader, Florence, Conrad, Anne“…Modified vaccinia virus Ankara vaccine (MVA-BN; Bavarian Nordic) is recommended to contacts of mpox cases up to 14 days post-exposure but the effectiveness of this strategy is unknown. …”
Publicado 2022
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288por Chapman, Rosamund, van Diepen, Michiel, Douglass, Nicola, Hermanus, Tandile, Moore, Penny L., Williamson, Anna-Lise“…The combination of mosaic Gag and CAP256 envelope in an HIV vaccine regimen comprising DNA prime and modified vaccinia Ankara (MVA) boost followed by protein boost has previously been shown to generate robust autologous Tier 2 neutralizing antibodies (nAbs) in rabbits. …”
Publicado 2023
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290“…METHODS: Subjects were recruited from the Sankara Nethralaya Diabetic Retinopathy Epidemiology And Molecular-genetics Study (SN-DREAMS), a cross-sectional study between 2003 and 2006; the data were analyzed for the1414 eligible subjects with diabetes. …”
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291por Rani, Padmaja Kumari, Raman, Rajiv, Gella, Laxmi, Kulothungan, Vaitheeswaran, Sharma, TarunEnlace del recurso
Publicado 2012
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292“…The subjects were newly diagnosed pulmonary TB patients from four districts in East Nusa Tenggara. Knowledge, perception of TB, and other related factors were assessed prior to the treatment. …”
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294por Raadsen, Matthijs P, Dahlke, Christine, Fathi, Anahita, Lamers, Mart M, van den Doel, Petra, Zaeck, Luca M, van Royen, Martin E, de Bruin, Erwin, Sikkema, Reina, Koopmans, Marion, van Gorp, Eric C M, Sutter, Gerd, de Vries, Rory D, Addo, Marylyn M, Haagmans, Bart L“…Modified vaccinia virus Ankara (MVA) is used as a vaccine against monkeypox virus and as a viral vaccine vector. …”
Publicado 2023
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295por Bella, Ángela, Arrizabalaga, Leire, Di Trani, Claudia Augusta, Gonzalez-Gomariz, Jose, Gomar, Celia, Russo-Cabrera, Joan Salvador, Olivera, Irene, Cirella, Assunta, Fernandez-Sendin, Myriam, Alvarez, Maite, Teijeira, Alvaro, Atay, Cigdem, Medina-Echeverz, José, Hinterberger, Maria, Hochrein, Hubertus, Melero, Ignacio, Berraondo, Pedro, Aranda, Fernando“…In order to restore antitumor immunity subverted by tumor cells in this location, we evaluated intraperitoneal administrations of modified vaccinia virus Ankara (MVA) engineered to express single-chain interleukin 12 (scIL-12) to increase antitumor immune responses. …”
Publicado 2023
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297por Zimmerling, Stefan, Waibler, Zoe, Resch, Theresa, Sutter, Gerd, Schwantes, Astrid“…BACKGROUND: Modified vaccinia virus Ankara (MVA) is a highly attenuated virus and a promising vaccine vector with potent immune stimulating properties. …”
Publicado 2013
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298“…This study tested the in vitro efficacy of three formulations of povidone iodine (PVP-I: 4% PVP-I skin cleanser, 7.5% PVP-I surgical scrub, and 1% PVP-I gargle/mouthwash) against a reference virus (Modified vaccinia virus Ankara, MVA) and MERS-CoV. METHODS: According to EN14476, a standard suspension test was used to assess virucidal activity against MVA and large volume plating was used for MERS-CoV. …”
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299por Chiuppesi, Flavia, Wussow, Felix, Scharf, Louise, Contreras, Heidi, Gao, Han, Meng, Zhuo, Nguyen, Jenny, Barry, Peter A., Bjorkman, Pamela J., Diamond, Don J.“…By developing a vaccine strategy based on soluble PC protein and using a previously generated Modified Vaccinia Ankara vector co-expressing all five PC subunits (MVA-PC), we compared HCMV NAb induction by homologous immunization using prime-boost vaccine regimen employing only PC protein or MVA-PC and heterologous immunization using prime-boost combinations of PC protein and MVA-PC. …”
Publicado 2017
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300por Shen, Xiaoying, Basu, Rahul, Sawant, Sheetal, Beaumont, David, Kwa, Sue Fen, LaBranche, Celia, Seaton, Kelly E., Yates, Nicole L., Montefiori, David C., Ferrari, Guido, Wyatt, Linda S., Moss, Bernard, Alam, S. Munir, Haynes, Barton F., Tomaras, Georgia D., Robinson, Harriet L.“…One novel approach comprises priming with DNA and boosting with modified vaccinia virus Ankara (MVA) expressing HIV-1 Env on virus-like particles. …”
Publicado 2017
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